Are differences in interleukin 10 production associated with joint damage?

Rheumatology

Volumn 39, Issue 11, 2000, Pages 1180-1188

  Huizinga, T W J ^a   Keijsers, V ^a   Yanni, G ^b   Hall, M ^b   Ramage, W ^b   Lanchbury, J ^b   Pitzalis, C ^b   Drossaers Bakker, W K ^a   Westendorp, R G J ^a   Breedveld, F C ^a   Panayi, G ^b   Verweij, C L ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Genotypes; Interleukin 10; Joint damage

Indexed keywords

INTERLEUKIN 10; MESSENGER RNA; PROTEIN;

ADULT; AGED; ALLELE; ARTICLE; BIOPSY; BONE EROSION; COHORT ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; FOOT; GENE LOCUS; GENETIC POLYMORPHISM; GENOTYPE; HAND; HUMAN; JOINT DESTRUCTION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROMOTER REGION; PROSPECTIVE STUDY; PROTEIN SYNTHESIS; RHEUMATOID ARTHRITIS; SCORING SYSTEM; SYNOVIUM; X RAY;

EID: 0033693715     PISSN: 14620324     EISSN: None     Source Type: Journal    
DOI: 10.1093/rheumatology/39.11.1180     Document Type: Article

References (44)

1. Two inhibitors of pro-inflammatory cytokine release, interleukin-10 and interleukin-4, have contrasting effects on release of soluble p75 tumor necrosis factor receptor by cultured monocytes
2. Regulatory effects of IL-13 on synovial fluid macrophages and blood monocytes from patients with inflammatory arthritis
3. Inhibitory effects of interleukin-10 on synovial cells of rheumatoid arthritis
4. Interleukin-10 suppresses the development of collagen type II-induced arthritis and ameliorates sustained arthritis in rats
5. Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis: Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction
6. Regulatory role of interleukin 10 in joint inflammation and cartilage destruction in murine streptococcal cell wall (SCW) arthritis. More therapeutic benefit with IL-4/IL-10 combination therapy than with IL-10 treatment alone
7. V-H usage and somatic hypermutation in peripheral blood B cells of patients with rheumatoid arthritis (RA)
8. IL-10 and arthritis
9. Systemic viral interleukin-10 gene delivery prevents cartilage invasion by human rheumatoid synovial tissue engrafted in scid mice
10. Genetic influence on cytokine production and fatal meningococcal disease
11. Genetic influence on cytokine production in meningococcal disease
12. Anti-inflammatory cytokine profile and mortality in febrile patients
13. In vivo production of interleukin-10 by non-T cells in rheumatoid arthritis, Sjogren's syndrome, and systemic lupus erythematosus: A potential mechanism of B lymphocyte hyperactivity and autoimmunity
14. Dysregulation of interleukin-10 production in relatives of patients with systemic lupus erythematosus
15. Interleukin 10 secretion in relation to human IL-10 locus haplotypes
16. Polymorphic haplotypes of the interleukin-10 5' flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis
17. An investigation of polymorphism in the IL-10-gene promoter
18. TNFα gene polymorphisms in RA: Association with susceptibility to, or severity of, disease?
19. The severity of RA: A 6-year follow-up study of younger women with symptoms of recent onset
20. Reduction of the risk of rheumatoid arthritis among women who take oral contraceptives
21. Long-term course and outcome of functional capacity in rheumatoid arthritis: The effect of disease activity and radiologic damage over time
22. Radiographic progression on radiographs of hands and feet during the first 3 years of rheumatoid arthritis measured according to Sharp's method (van der Heijde modification)
23. Determination of TNF and IL-10 production in a whole-blood stimulation system: Assessment of laboratory error and individual variation
24. I1 10 inhibits cytokine synthesis by human monocytes: An autoregulatory role of I1 10 produced by monocytes
25. Expression of mRNA for Cox1 and Cox2 in human tissues
26. Quantification of mRNA by PCR
27. Biotinylated DRB sequence-specific oligonucleotides. Comparison to serologic HLA-DR typing of organ donors in Eurotransplant
28. Neuropsychiatric SLE is associated with imbalance in IL-10 promoter haplotypes
29. IL-10 gene promoter polymorphisms in rheumatoid arthritis
30. IL-10 promoter polymorphisms in RA and Felty's syndrome
31. IL-10. A potential therapy for allergic inflammation?
32. Studies with IL-10(-/-) mice: An overview
33. IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes
34. Interleukin-10 microsatellite polymorphisms and IL-10 locus alleles in rheumatoid arthritis susceptibility
35. In RA IL-10 production by T cell stimulation of mononuclear cells strongly correlates with (progression) of joint destruction
36. Patterns of radiological progression in early rheumatoid arthritis: Results of an 8 year prospective study
37. Apoptosis in rheumatoid arthritis: P53 overexpression in rheumatoid arthritis synovium
38. Invasive fibroblast-like synoviocytes in rheumatoid arthritis: Passive responders or transformed aggressors?
39. Genetic variation in the interleukin 10 gene promoter and systemic lupus erythematosus
40. Haplotype associated with low IL-10 production in patients with severe asthma
41. Interleukin-10 promoter polymorphisms in Southern Chinese patients with systemic lupus erythematosus
42. Cytokine gene polymorphisms associating with severe acute graft-versus-host disease in HLA-identical sibling transplants
43. Microsatellite alleles and SNP combine to form four major haplotype families at the human IL-10 locus
44. Genetic control of arthritis onset, severity and chronicity in a model for rheumatoid arthritis in rats