Interleukin-10 promoter polymorphisms in rheumatoid arthritis and Felty's syndrome

British Journal of Rheumatology

Volumn 37, Issue 9, 1998, Pages 988-991

  Coakley, G ^a   Mok, C C ^a   Hajeer, A H ^a   Ollier, W E R ^a   Turner, D ^a   Sinnott, P J ^a   Hutchinson, I V ^a   Panayi, G S ^a   Lanchbury, J S ^a  

^a NONE

Author keywords

IL 10; Polymorphism; Rheumatoid arthritis

Indexed keywords

INTERLEUKIN 10; RESTRICTION ENDONUCLEASE;

ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; FELTY SYNDROME; GENE FREQUENCY; GENETIC POLYMORPHISM; HAPLOTYPE; HEREDITY; HUMAN; MAJOR CLINICAL STUDY; OLIGONUCLEOTIDE PROBE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; RHEUMATOID ARTHRITIS;

EID: 0031716610     PISSN: 02637103     EISSN: None     Source Type: Journal    
DOI: 10.1093/rheumatology/37.9.988     Document Type: Article

References (16)

1. Florentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 1989;170:2081-95.
2. de Waal Malefyt R, Abrams J, Bennett B, Figdor CG, de Vries JE. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 1991;174:1209-20.
3. Go NF, Castle BE, Barrett R et al. Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells. J Exp Med 1990;172:1625-31.
4. Rousset F, Garcia E, Defranc T et al. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc Natl Acad Sci USA 1992;89:1890-3.
5. Lapadula G, Iannone F, Dell'Accio F, Covelli M, Pipitone V. Interleukin-10 in rheumatoid arthritis. Clin Exp Rheumatol 1995;13:629-32.
6. Cush JJ, Splawski JB, Thomas R et al. Elevated interleukin-10 levels in patients with rheumatoid arthritis. Arthritis Rheum 1995;38:96-104.
7. Schulze-Koops H, Davis LS, Kavanaugh AF, Lipsky PE. Elevated cytokine messenger RNA levels in the peripheral blood of patients with rheumatoid arthritis suggest different degrees of myeloid cell activation. Arthritis Rheum 1997;40:639-47.
8. Cohen SB, Katsikis PD, Chu CQ et al. High level of interleukin-10 production by the activated T cell population within the rheumatoid synovial membrane. Arthritis Rheum 1995;38:946-52.
9. Bucht A, Larsson P, Weisbrot L et al. Expression of interferon-gamma (IFN-gamma), IL-10, IL-12 and transforming growth factor-beta (TGF-beta) mRNA in synovial fluid cells from patients in the early and late phases of rheumatoid arthritis (RA). Clin Exp Immunol 1996;103:357-67.
10. Isomaki P, Luukkainen R, Saario R, Toivanen P, Punnonen J. Interleukin-10 functions as an antiinflammatory cytokine in rheumatoid synovium. Arthritis Rheum 1996;39:386-95.
11. van Roon JA, van Roy JL, Gmelig-Meyling FH, Lafeber FP, Bijlsma JW. Prevention and reversal of cartilage degradation in rheumatoid arthritis by interleukin-10 and interleukin-4. Arthritis Rheum 1996;39:829-35.
12. Bowman SJ, Corrigall V, Panayi GS, Lanchbury JS. Hematologic and cytofluorographic analysis of patients with Felty's syndrome. A hypothesis that a discrete event leads to large granular lymphocyte expansions in this condition. Arthritis Rheum 1995;38:1252-9.
13. Turner DM, Williams DM, Sankaran D, Lazarus M, Sinnott PJ, Hutchinson IV. An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet 1997;24:1-8.
14. Kube D, Platzer C, von Knethen A et al. Isolation of the human interleukin 10 promoter. Characterization of the promoter activity in Burkitt's lymphoma cell lines. Cytokine 1995;7:1-7.
15. Westendorp RG, Langermans JA, Huizinga TW et al. Genetic influence on cytokine production and fatal meningococcal disease. Lancet 1997;349:170-3.
16. Eskdale J, Wordsworth P, Bowman S, Field M, Gallagher G. Association between polymorphisms at the human IL-10 locus and systemic lupus erythematosus. Tissue Antigens 1997;49:635-9.