A histone variant, Htz1p, and a Sir1p-like protein, Esc2p, mediate silencing at HMR

Molecular Cell

Volumn 6, Issue 4, 2000, Pages 769-780

  Dhillon, Namrita ^a   Kamakaka, Rohinton T ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; NUCLEAR PROTEIN; NUCLEAR PROTEIN ESC2P; NUCLEAR PROTEIN SIR1P; UNCLASSIFIED DRUG;

ARTICLE; CHROMATIN STRUCTURE; GENE LOCUS; GENE SILENCING; MUTANT; NONHUMAN; SILENCER GENE; SILENT GENE; YEAST;

EID: 0033638234     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)00076-9     Document Type: Article

References (50)

1. Chromatin assembly: Biochemical identities and genetic redundancy
2. A conserved histone variant enriched in nucleoli of mammalian cells
3. Analysis of a histone H2A variant from fission yeast: Evidence for a role in chromosome stability
4. Yeast heterochromatin is a dynamic structure that requires silencers continuously
5. The two-hybrid system: A method to identify and clone genes for proteins that interact with a protein of interest
6. Targeting of SIR1 protein establishes transcriptional silencing at HM loci and telomeres in yeast
7. Regions of variant histone His2AvD required for Drosophila development
8. The boundaries of the silenced HMR domain in Saccharomyces cerevisiae
9. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit
10. Yeast histone H4 N-terminal sequence is required for promoter activation in vivo
11. Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci
12. The origin recognition complex, SIR1, and the S phase requirement for silencing
13. A region of the Sir1 protein dedicated to recognition of a silencer and required for interaction with the Orc1 protein in Saccharomyces cerevisiae
14. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites
15. Yeast heterochromatin: Regulation of its assembly and inheritance by histones
16. The regulation of euchromatin and heterochromatin by histones in yeast
17. Sir2 links chromatin silencing, metabolism, and aging
18. Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: A molecular model for the formation of heterochromatin in yeast
19. Forkhead genes in transcriptional silencing, cell morphology and the cell cycle. Overlapping and distinct functions for fkh1 and fkh2 in Saccharomyces cerevisiae
20. Silencers are required for inheritance of the repressed state in yeast
21. A likely histone H2A.F/Z variant in Saccharomyces cerevisiae
22. SUMO-1: Ubiquitin gains weight
23. Silencers and locus control regions: Opposite sides of the same coin
24. Chromatin structure of transcriptionally competent and repressed genes
25. Sir- and silencer-independent disruption of silencing in Saccharomyces by Sas10p
26. Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast
27. A nucleolar protein that affects mating efficiency in Saccharomyces cerevisiae by altering the morphological response to pheromone
28. Histone H2A.Z is widely but nonrandomly distributed in chromosomes of Drosophila melanogaster
29. All four core histone N-termini contain sequences required for the repression of basal transcription in yeast
30. Genetic analysis of Rap1p/Sir3p interactions in telomeric and HML silencing in Saccharomyces cerevisiae
31. Silencers and domains of generalized repression
32. A synthetic silencer mediates SIR-dependent functions in Saccharomyces cerevisiae
33. Cse4p is a component of the core centromere of Saccharomyces cerevisiae
34. Role of DNA replication in the repression of silent mating type loci in yeast
35. Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1
36. A rapid method for localized mutagenesis of yeast genes
37. Epigenetic inheritance of transcriptional states in S. cerevisiae
38. Immunofluorescence methods for yeast
39. High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating-type locus HMRa
40. Gene overexpression in studies of Saccharomyces cerevisiae
41. HMR-l is an origin of replication and a silencer in Saccharomyces cerevisiae
42. Histone variants in mouse centromeric chromatin
43. Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex
44. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
45. Purification and characterization of CAF-l, a human cell factor required for chromatin assembly during DNA replication in vitro
46. An unusual form of transcriptional silencing in yeast ribosomal DNA
47. Temporal and spatial association of histone H2A variant hv1 with transcriptionally competent chromatin during nuclear development in Tetrahymena thermophila
48. The SIR1 gene of Saccharomyces cerevisiae and its role as an extragenic suppressor of several mating-defective mutants
49. Epigenetic switching of transcriptional states: Cis- and trans-acting factors affecting establishment of silencing at the HMR locus in Saccharomyces cerevisiae
50. Role of interactions between the origin recognition complex and SIR1 in transcriptional silencing