The origin recognition complex, SIR1, and the S phase requirement for silencing

Science

Volumn 276, Issue 5318, 1997, Pages 1547-

  Fox, Catherine A ^a,b   Ehrenhofer Murray, Ann E ^a   Loo, Stephen ^a   Rine, Jasper ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL CYCLE S PHASE; COMPLEX FORMATION; DNA REPLICATION; GENETIC TRANSCRIPTION; MOLECULAR RECOGNITION; PRIORITY JOURNAL; SILENCER GENE; TELOMERE;

ALDOSE-KETOSE ISOMERASES; CHROMATIN; CHROMOSOMES, FUNGAL; DNA REPLICATION; DNA, FUNGAL; DNA-BINDING PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; ORIGIN RECOGNITION COMPLEX; RECOMBINANT FUSION PROTEINS; S PHASE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SILENT INFORMATION REGULATOR PROTEINS, SACCHAROMYCES CEREVISIAE; TELOMERE; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

EID: 1842367918     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.276.5318.1547     Document Type: Article

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42. We thank D. Gottschling for constructs and the members of our laboratory for stimulating discussions. Supported by a grant from the National Institutes of Health (GM31105) (J.R.), by postdoctoral fellowships from the California Division of the American Cancer Society and the Leukemia Society of America (C.A.F.), by postdoctoral grants from the Swiss National Science Foundation and the Janggen-Pöhn Foundation (A.E.E.-M.), and by a Howard Hughes Medical Research Institute predoctoral fellowship (S.L.). C.A.F. thanks M. D. Sheets for discussion and support. Core support was provided by a National Institute of Environmental Health Sciences Mutagenesis Center grant to B. N. Ames.