HMR-I is an origin of replication and a silencer in Saccharomyces cerevisiae

Genetics

Volumn 151, Issue 2, 1999, Pages 521-529

  Rivier, David H ^a   Ekena, Joanne L ^a   Rine, Jasper ^b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME DELETION; DNA REPLICATION ORIGIN; GENE FUNCTION; GENE SILENCING; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SILENCER GENE;

DNA REPLICATION; DNA, FUNGAL; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; REPLICATION ORIGIN; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES CEREVISIAE;

EID: 0032956283     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. ABRAHAM, J., J. FELDMAN, K. A. NASMYTH, J. N. STRATHERN, A. J. KLAR et al., 1983 Sites required for position-effect regulation of mating-type information in yeast. Cold Spring Harbor Symp. Quant. Biol. 47: 989-998.
2. ABRAHAM, J., K. A. NASMYTH, J. N. STRATHERN, A. J. KLAR and J. B. HICKS, 1984 Regulation of mating-type information in yeast. Negative control requiring sequences both 5′ and 3′ to the regulated region. J. Mol. Biol. 176: 307-331.
3. APARICIO, O. M., and D. E. GOTTSCHLING, 1994 Overcoming telomeric silencing: a trans-activator competes to establish gene expression in a cell cycle-dependent way. Genes Dev. 8: 1133-1146.
4. APARICIO, O. M., B. L. BILLINGTON and D. E. GOTTSCHLING, 1991 Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae. Cell 66: 1279-1287.
5. BOSCHERON, C., L. MAILLET, S. MARCAND, M. TSAI-PFLUGFELDER, S. M. GASSER et al., 1996 Cooperation at a distance between silencers and proto-silencers at the yeast HML locus. EMBO J. 15: 2184-2195.
6. BRAND, A. H., L. BREEDEN, J. ABRAHAM, R. STERNGLANZ and K. NASMYTH, 1985 Characterization of a "silencer" in yeast: a DNA sequence with properties opposite to those of a transcriptional enhancer. Cell 41: 41-48.
7. BRAND, A. H., G. MICKLEM and K. NASMYTH, 1987 A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation. Cell 51: 709-719.
8. BREWER, B. J., and W. L. FANGMAN, 1987 The localization of replication origins on ARS plasmids in S. cerevisiae. Cell 51: 463-471.
9. BRYK, M., M. BANERJEE, M. MURPHY, K. E. KNUDSEN, D. J. GARFINKEL et al., 1997 Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast. Genes Dev. 11: 255-269.
10. BUCHMAN, A. R., W. J. KIMMERLY, J. RINE and R. D. KORNBERG, 1988a Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae. Mol. Cell. Biol. 8: 210-225.
11. BUCHMAN, A. R., N. F. LUE and R. D. KORNBERG, 1988b Connections between transcriptional activators, silencers, and telomeres as revealed by functional analysis of a yeast DNA-binding protein. Mol. Cell. Biol. 8: 5086-5099.
12. DILLIN, A., and J. RINE, 1997 Separable functions of ORC5 in replication initiation and silencing in Saccharomyces cerevisiae. Genetics 147: 1053-1062.
13. DUBEY, D. D., L. R. DAVIS, S. A. GREENFEDER, L. Y. ONG, J. G. ZHU et al., 1991 Evidence suggesting that the ARS elements associated with silencers of the yeast mating-type locus HML do not function as chromosomal DNA replication origins. Mol. Cell. Biol. 11: 5346-5355.
14. FELDMAN, J. B., J. B. HICKS and J. R. BROACH, 1984 Identification of sites required for repression of a silent mating type locus in yeast. J. Mol. Biol. 178: 815-834.
15. FOSS, M., F. J. MCNALLY, P. LAURENSON and J. RINE, 1993 Origin recognition complex (ORC) in transcriptional silencing and DNA replication in S. cerevisiae. Science 262: 1838-1844.
16. GARDNER, K. A., J. RINE and C. A. FOX, 1999 A region of the Sir1 protein dedicated to recognition of a silencer and required for interaction with the Orc1 protein in Saccharomyces cerevisiae. Genetics 151: 31-44.
17. GIETZ, R. D., and R. H. SCHIESTL, 1991 Applications of high efficiency lithium acetate transformation of intact yeast cells using single-stranded nucleic acids as carrier. Yeast 7: 253-263.
18. GOTTSCHLING, D. E., O. M. APARICIO, B. L. BILLINGTON and V. A. ZAKIAN, 1990 Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell 63: 751-762.
19. GRUNSTEIN, M., 1997 Molecular model for telomeric heterochromatin in yeast. Curr. Opin. Cell. Biol. 9: 383-387.
20. GRUNSTEIN, M., 1998 Yeast heterochromatin: regulation of its assembly and inheritance by histones. Cell 93: 325-328.
21. GUTHRIE, C., and G. R. FINK, 1991 Guide to Yeast Genetics and Molecular Biology. Academic Press, San Diego.
22. HECHT, A., T. LAROCHE, S. STRAHL-BOLSINGER, S. M. GASSER and M. GRUNSTEIN, 1995 Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast. Cell 80: 583-592.
23. HECHT, A., S. STRAHL-BOLSINGER and M. GRUNSTEIN, 1996 Spreading of transcriptional repressor SIR3 from telomeric heterochromatin. Nature 383: 92-96.
24. KIMMERLY, W. J., and J. RINE, 1987 Replication and segregation of plasmids containing cis-acting regulatory sites of silent mating-type genes in Saccharomyces cerevisiae are controlled by the SIR genes. Mol. Cell. Biol. 7: 4225-4237.
25. KIMMERLY, W., A. BUCHMAN, R. KORNBERG and J. RINE, 1988 Roles of two DNA-binding factors in replication, segregation and transcriptional repession mediated by a yeast silencer. EMBO J. 7: 2241-2253.
26. LAURENSON, P., and J. RINE, 1992 Silencers, silencing, and heritable transcriptional states. Microbiol. Rev. 56: 543-560.
27. LOO, S., and J. RINE, 1994 Silencers and domains of generalized repression. Science 264: 1768-1771.
28. LOO, S., P. LAURENSON, M. FOSS, A. DILLIN and J. RINE, 1995 Roles of ABF1, NPL3, and YCL54 in silencing in Saccharomyces cerevisiae. Genetics 141: 889-902.
29. LUSTIG, A. J., 1998 Mechanisms of silencing in Saccharomyces cerevisiae. Curr. Opin. Genet. Dev. 8: 233-239.
30. MCNALLY, F. J., and J. RINE, 1991 A synthetic silencer mediates SIR-dependent functions in Saccharomyces cerevisiae. Mol. Cell. Biol. 11: 5648-5659.
31. MORETTI, P., K. FREEMAN, L. COODLY and D. SHORE, 1994 Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1. Genes Dev. 8: 2257-2269.
32. NEWLON, C. S., and J. F. THEIS, 1993 The structure and function of yeast ARS elements. Curr. Opin. Genet. Dev. 3: 752-758.
33. PILLUS, L., and J. RINE, 1989 Epigenetic inheritance of transcriptional states in S. cerevisiae. Cell 59: 637-647.
34. RENAULD, H., O. M. APARICIO, P. D. ZIERATH, B. L. BILLINGTON, S. K. CHHABLANI et al., 1993 Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage. Genes Dev. 7: 1133-1145.
35. RINE, J., and I. HERSKOWITZ, 1987 Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics 116: 9-22.
36. RIVIER, D. H., and J. RINE, 1992a An origin of DNA replication and a transcription silencer require a common element. Science 256: 659-663.
37. RIVIER, D. H., and J. RINE, 1992b Silencing: the establishment and inheritance of stable, repressed transcription states. Curr. Opin. Genet. Dev. 2: 286-292.
38. ROY, A., F. EXINGER and R. LOSSON, 1990 cis- and trans-acting regulatory elements of the yeast URA3 promoter. Mol. Cell. Biol. 10: 5257-5270.
39. SHERMAN, F., 1991 Getting started with yeast. Methods Enzymol. 194: 3-21.
40. SHORE, D., and K. NASMYTH, 1987 Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements. Cell 51: 721-732.
41. SIKORSKI, R. S., and P. HIETER, 1989 A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27.
42. SMITH, J. S., and J. D. BOEKE, 1997 An unusual form of trancriptional silencing in yeast ribosomal DNA. Genes Dev 11: 241-254.
43. STRAHL-BOLSINGER, S., A. HECHT, K. LUO and M. GRUNSTEIN, 1997 SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev. 11: 83-93.
44. SUSSEL, L., D. VANNIER and D. SHORE, 1993 Epigenetic switching of transcriptional states: cis- and trans-acting factors affecting establishment of silencing at the HMR locus in Saccharomyces cerevisiae. Mol. Cell. Biol. 13: 3919-3928.
45. TRIOLO, T., and R. STERNGLANZ, 1996 Role of interactions between the origin recognition complex and SIR1 in transcriptional silencing. Nature 381: 251-253.