The transmembrane sequence of human histocompatibility leukocyte antigen (HLA)-C as a determinant in inhibition of a subset of natural killer cells

Journal of Experimental Medicine

Volumn 189, Issue 8, 1999, Pages 1265-1274

  Davis, Daniel M ^a   Mandelboim, Ofer ^a   Luque, Isabel ^a   Baba, Eishi ^a   Boyson, Jonathan ^a   Strominger, Jack L ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

Class I MHC protein; Cysteine; NK cells; NK receptors; Transmembrane sequence

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

AMINO ACID SEQUENCE; ANTIGEN RECOGNITION; ARTICLE; HLA SYSTEM; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; NATURAL KILLER CELL; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; B-LYMPHOCYTES; CLONE CELLS; CLONING, MOLECULAR; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HLA-C ANTIGENS; HUMANS; KILLER CELLS, NATURAL; LYMPHOCYTE SUBSETS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; RECEPTORS, CELL SURFACE; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT;

EID: 0033583430     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.189.8.1265     Document Type: Article

References (51)

1. Trinchieri, G. 1989. Biology of natural killer cells. Adv. Immunol. 47:187-376.
2. Ljunggren, H.-G., and K. Karre. 1990. In search of the missing self: MHC molecules and NK recognition. Immunol. Today. 11:7-10.
3. Karre, K. 1997. How to recognise a foreign submarine. Immunol. Rev. 155:5-9.
4. Malnati, M.S., P. Lusso, E. Ciccone, A. Moretta, L. Moretta, and E.O. Long. 1993. Recognition of virus-infected cells by natural killer cell clones is controlled by polymorphic target cell elements. J. Exp. Med. 178:961-969.
5. Colonna, M., and J. Samaridis. 1995. Cloning of immunoglobulin superfamily members associated with HLA-C allele and HLA-B recognition by human natural killer cells. Science. 268:405-408.
6. Wagtmann, N., R. Biassoni, C. Cantoni, S. Verdiani, M.S. Malnati, M. Vitale, C. Bottino, L. Moretta, A. Moretta, and E.O. Long. 1995. Molecular clones of the p58 NK cell receptor reveal immunoglobulin related molecules with diversity in both the extra- and intra-cellular domains. Immunity. 2:439-449.
7. D'Andrea, A., C. Chang, K. Franz-Bacon, T. McClanahan, J.H. Phillips, and L.L. Lanier. 1995. Molecular cloning of NKB1: a natural killer cell receptor for HLA-B haplotype. J. Immunol. 155:2306-2310.
8. Lanier, L.L., B.C. Corliss, J. Wu, C. Leong, and J.H. Phillips. 1998. Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells. Nature. 391: 703-707.
9. Moretta, A., S. Sivori, M. Vitale, D. Pende, L. Morelli, R. Augugliaro, C. Bottino, and L. Moretta. 1995. Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells. J. Exp. Med. 182:875-884.
10. Colonna, M., F. Navarro, T. Bellon, M. Liano, P. Garcia, J. Samaradis, L. Angman, M. Cella, and M. Lopez-Botet. 1997. A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J. Exp. Med. 186:1809-1818.
11. Cosman, D., N. Fanger, L. Borges, M. Kubin, W. Chin, L. Peterson, and M.-L. Hsu. 1997. A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. Immunity. 7:273-282.
12. Borges, L., M.-L. Hsu, N. Fanger, M. Kubin, and D. Cosman. 1997. A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules. J. Immunol. 159:5192-5196.
13. Selvakumar, A., U. Steffans, and B. Dupont. 1996. NK cell receptor gene of the KIR family with two IG domains but highest homology to KIR receptors with three IG domains. Tissue Antigens. 48:285-295.
14. Cantoni, C., S. Verdiani, M. Falco, A. Pessino, M. Cilli, R. Conte, D. Pende, M. Ponte, M.S. Mikaelsson, L. Moretta, et al. 1998. p49, a putative HLA class I-specific inhibitory NK receptor belonging to the imniunoglobulin superfamily. Eur. J. Immunol. 28:1980-1990.
15. Lopez-Botet, M., J.J. Perez-Villar, M. Carretero, A. Rodriguez, I. Melero, T. Bellon, M. Liano, and F. Navarro. 1997. Structure and function of the CD94 C-type lectin receptor complex involved in recognition of HLA class I molecules. Immunol Rev. 155:165-174.
16. Borrego, F., M. Ulbert, E.H. Weiss, J.E. Coloigen, and A.G. Brooks. 1998. Recognition of human histocompatibility leukocyte antigen (HLA-E) complexed with HLA class I signal sequence-derived peptide by CD94/NKG2 confers protection from natural killer cell-mediated lysis. J. Exp. Med. 187: 813-818.
17. Braud, V.M., D.S. Allan, C.A. O'Callaghan, K. Soderstrom, A. D'Andrea, G.S. Ogg, S. Lazetic, N.T. Young, J.I. Bell, L.L. Lanier, et al. 1998. HLA-E binds to natural killer cell receptors CD94/NKG2A, B, and C. Nature. 391:795-799.
18. Lee, N., M. Liano, M. Carretero, A. Ishitani, F. Navarro, M. Lopez-Botet, and D.E. Geraghty. 1998. HLA-E is a major ligand for the natural killer inhibitory receptor CD94/ NKG2. Proc. Natl. Acad. Sci. USA. 95:5199-5204.
19. Phillips, J.H., J.E. Gumperz, P. Parham, and L.L. Lanier. 1995. Superantigen dependent, cell mediated cytotoxicity inhibited by MHC class I receptors on T lymphocytes. Science. 268:403-405.
20. Mandelboim, O., D.M. Davis, H.T. Reyburn, M. ValesGomez, E.G. Sheu, L. Pazmany, and J.L. Strominger. 1996. Enhancement of class II-restricted T cell responses by costimulatory NK receptors for class I MHC proteins. Science. 274: 2097-2100.
21. Valiante, N.M., M. Uhrberg, H.G. Shilling, K. Lienart-Weidenbach, K.L. Arnett, A. D'Andrea, J.H. Phillips, L.L. Lanier, and P. Parham. 1997. Functionally and structurally distinct NK cell receptor repertoires in peripheral blood of two human donors. Immunity. 7:739-751.
22. Uhrberg, M., N.M. Valiante, B.P. Shum, H.G. Shilling, K. Lienert-Weidenbach, B. Corliss, D. Tyan, L.L. Lanier, and P. Parham. 1997. Human diversity in killer cell inhibitory receptor genes. Immunity. 7:753-763.
23. Renard, V., A. Cambiaggi, F. Vely, M. Blery, L. Olcese, S. Olivero, M. Bouchet, and E. Vivier. 1997. Transduction of cytotoxic signals in natural killer cells: a general model of fine tuning between activatory and inhibitory pathways in lymphocytes. Immunol. Rev. 155:205-221.
24. Lanier, L.L. 1997. NK cells: from no receptors to too many. Immunity. 6:371-378.
25. Lanier, L.L. 1998. NK cell receptors. Adv. Immunol. 16: 359-393.
26. McMaster, M.T., C.L. Librach, Y. Zhou, K.-H. Lim, M.J. Janatpour, R. DeMars, S. Kovats, C. Damsky, and S.J. Fisher. 1995. Human placental HLA-G expression is restricted to differentiated cytotrophoblasts. J. Immunol. 154:3771-3778.
27. Pazmany, L., O. Mandelboim, M. Vales-Gomez, D.M. Davis, H.T. Reyburn, and J.L. Strominger. 1996. Protection from natural killer cell-mediated lysis by HLA-G expression on target cells. Science. 274:792-795.
28. Mandelboim, O., H.T. Reyburn, M. Vales-Gomez, L. Pazmany, M. Colonna, G. Borsellino, and J.L. Strominger. 1996. Protection from lysis by natural killer cells of group 1 and 2 specificity is mediated by residue 80 in human histocompatibility leukocyte antigen C alleles and also occurs with empty major histocompatibility complex molecules. J. Exp. Med. 184:913-922.
29. Davis, D.M., H.T. Reyburn, L. Pazmany, I. Chiu, O. Mandelboim, and J.L. Strominger. 1997. Impaired spontaneous endocytosis of HLA-G. Eur. J. Immunol. 27:2714-2719.
30. Shimizu, Y., and R.J. DeMars. 1989. Production of human cells expressing individual transferred HLA-A, -B, -C, genes using an HLA-A, -B, -C, null human cell line. J. Immunol. 142:3320-3328.
31. Parham, P., C.J. Barnstable, and W.F. Bodmer. 1979. Use of monoclonal antibody (W6/32) in structural studies of HLA-A,B,C antigens. J. Immunol. 23:342-349.
32. Mandelboim, O., L. Pazmany, D.M. Davis, M. Vales-Gomez, H.T. Reyburn, B. Rybalov, and J.L. Strominger. 1997. Multiple receptors for HLA-G on human natural killer cells. Proc. Natl. Acad. Sci. USA. 94:14666-14670.
33. Giacomini, P., A. Beretta, M.R. Nicotra, G. Ciccarelli, A. Martayan, C. Cerboni, L. Lopalco, D. Bini, L. Delfino, G.B. Ferrara, et al. 1997. HLA-C heavy chains free of β2-microglobulin: distribution in normal tissues and neoplastic lesions of non-lymphoid origin and interferon-γ responsiveness. Tissue Antigens. 50:555-566.
34. Brodsky, F.M., W.F. Bodmer, and P. Parham. 1979. Characterization of a monoclonal anti-beta 2-microglobulin anti-body and its use in the genetic and biochemical analysis of major histocompatibility antigens. Eur. J. Immunol. 9:536-545.
35. Lanier, L.L., J.E. Gumperz, P. Parham, I. Melero, M. Lopez-Botet, and J.H. Phillips. 1995. The NKB1 and HP3E4 NK cell receptors are structurally distinct glycoproteins and independently recognise polymorphic HLA-B and HLA-C molecules. J. Immunol. 154:3320-3327.
36. Melero, I., A. Salmeron, M.A. Balboa, J. Aramburu, and M. Lopez-Botet. 1994. Tyrosine kinase-dependent activation of human NK cell functions upon stimulation through a 58-kDa surface antigen selectively expressed on discrete subsets of NK cell and T lymphocytes. J. Immunol. 152:1662-1673.
37. + natural killer (NK) cells by expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition. J. Exp. Med. 172:1589-1598.
38. Rajagopalan, S., and E.O. Long. 1998. Zinc bound to the killer cell-inhibitory receptor modulates the negative signal in human NK cells. J. Immunol. 161:1299-1305.
39. Sentman, C.L., M.Y. Olsson-Alheim, U. Lendahl, and K. Karre. 1996. Influence of glycosylphosphatidylinositol-linked H-2Dd molecules on target cell protection and natural killer cell specificity in transgenic mice. Eur. J. Immunol. 26:2127-2132.
40. Bohuslav, J., T. Cinek, and V. Horejsi. 1993. Large, detergent-resistant complexes containing murine antigens Thy-1 and Ly-6 and protein tyrosine kinase p56lck. Eur. J. Immunol. 23:825-831.
41. Heldin, C.-H. 1995. Dimerization of cell surface receptors in signal transduction. Cell. 80:213-223.
42. Klemm, J.D., S.L. Schreiber, and G.R. Crabtree. 1998. Dimerization as a regulatory mechanism in signal transduction. Annu. Rev. Immunol. 16:569-592.
43. Szollosi, J., V. Horejsi, L. Bene, P. Angelisova, S. Damjanovich. 1996. Supramolecular complexes of MHC class I, MHC class II, CD20 and tetraspan molecules (CD53, CD81, and CD82) at the surface of a B cell line JY. J. Immunol. 157: 2939-2946.
44. Skov, S. 1998. Intracellular signal transduction mediated by ligation of MHC class I molecules. Tissue Antigens. 51:215-223.
45. Wagner, N., P. Engel, M. Vega, and T.F. Tedder. 1994. Ligation of MHC class I and class II molecules can lead to heterologous desensitization of signal transduction pathways that regulate homotypic adhesion in human lymphocytes. J. Immunol. 152:5275-5287.
46. Tscherning, T., and M.H. Claesson. 1994. Signal transduction via MHC class-I molecules in T cells. Scand. J. Immunol. 39:117-121.
47. Kaufman, J.F., M.S. Krangel, and J.L. Strominger. 1984. Cysteines in the transmembrane region of major histocompatibility antigens are fatty acylated via thioester bonds. J. Biol. Chem. 259:7230-7238.
48. Simons, K., and E. Ikonen. 1997. Functional rafts in cell membranes. Nature. 387:569-572.
49. Dan, N., and S.A. Safran. 1998. Effect of lipid characteristics on the structure of transmembrane proteins. Biophys. J. 75: 1410-1414.
50. Hasegawa, M., T. Sugimura, K. Kuraishi, Y. Shindo, and A. Kitahara. 1992. Microviscosity in AOT reverse micellar core determined with a viscosity sensitive fluorescence probe. Chem. Lett. 7:1373-1380.
51. Davis, D.M., D. McLoskey, D.J. Birch, P.R. Gellert, R.S. Kittlety, and R.M. Swart. 1996. The fluorescence and circular dichroism of proteins in reverse micelles: application to the photophysics of human serum albumin and N-acetyl-1-tryptophanamide. Biophys. Chem. 60:63-77.