메뉴 건너뛰기




Volumn 287, Issue 1, 1999, Pages 93-101

Peptides derived from HIV-1 Vif: A non-substrate based novel type of HIV-1 protease inhibitors

Author keywords

Aspartic protease inhibitor; HIV 1; HIV PR; Peptide mapping; Vif

Indexed keywords

PEPSIN A; PROTEINASE; PROTEINASE INHIBITOR; VIF PROTEIN; VIRUS PROTEIN;

EID: 0033582949     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.2585     Document Type: Article
Times cited : (27)

References (39)
  • 1
    • 0029618847 scopus 로고
    • Avian sarcoma leukemia virus protease linked to the adjacent gag polyprotein is enzymatically active
    • Arad G., Almog N., Bar-Meir R., Chorev M., Kotler M. Avian sarcoma leukemia virus protease linked to the adjacent gag polyprotein is enzymatically active. Virology. 214:1995;439-444.
    • (1995) Virology , vol.214 , pp. 439-444
    • Arad, G.1    Almog, N.2    Bar-Meir, R.3    Chorev, M.4    Kotler, M.5
  • 2
    • 0032426645 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Vif derived peptides inhibit the viral protease and arrest virus production
    • Baraz L., Friedler A., Blumenzweig I., Nussinov O., Chen N., Steinitz M., Gilon C., Kotler M. Human immunodeficiency virus type 1 Vif derived peptides inhibit the viral protease and arrest virus production. FEBS Letters. 441:1998;419-426.
    • (1998) FEBS Letters , vol.441 , pp. 419-426
    • Baraz, L.1    Friedler, A.2    Blumenzweig, I.3    Nussinov, O.4    Chen, N.5    Steinitz, M.6    Gilon, C.7    Kotler, M.8
  • 3
    • 0029916638 scopus 로고    scopus 로고
    • Saquinavir: An HIV proteinase inhibitor
    • Bragman K. Saquinavir: an HIV proteinase inhibitor. Advan. Exp. Med. Biol. 394:1996;305-317.
    • (1996) Advan. Exp. Med. Biol. , vol.394 , pp. 305-317
    • Bragman, K.1
  • 4
    • 0029742789 scopus 로고    scopus 로고
    • Synthesis and biological activity of NK-1 selective N-backbone cyclic analogs of the C-terminal hexapeptide of substance P
    • Byk G., Halle D., Zeltser I., Bitan G., Selinger Z., Gilon C. Synthesis and biological activity of NK-1 selective N-backbone cyclic analogs of the C-terminal hexapeptide of substance P. J. Med. Chem. 39:1996;3174.
    • (1996) J. Med. Chem. , vol.39 , pp. 3174
    • Byk, G.1    Halle, D.2    Zeltser, I.3    Bitan, G.4    Selinger, Z.5    Gilon, C.6
  • 5
    • 0029821868 scopus 로고    scopus 로고
    • Characterization of HIV-1 vif particle incorporaton
    • Camur D., Trono D. Characterization of HIV-1 vif particle incorporaton. J. Virol. 70:1996;6106-6111.
    • (1996) J. Virol. , vol.70 , pp. 6106-6111
    • Camur, D.1    Trono, D.2
  • 6
    • 0030015293 scopus 로고    scopus 로고
    • Vif-negative human immunodeficiency virus type 1 persistently replicates in primary macrophages producing attenuated progeny virus
    • Chowdhury L. H., Chao W., Potash M. J., Sova P., Gendelman H. E., Volsky D. J. Vif-negative human immunodeficiency virus type 1 persistently replicates in primary macrophages producing attenuated progeny virus. J. Virol. 70:1996;5336-5345.
    • (1996) J. Virol. , vol.70 , pp. 5336-5345
    • Chowdhury, L.H.1    Chao, W.2    Potash, M.J.3    Sova, P.4    Gendelman, H.E.5    Volsky, D.J.6
  • 7
    • 0028952146 scopus 로고
    • HIV population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy
    • Coffin J. HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy. Science. 267:1995;483-489.
    • (1995) Science , vol.267 , pp. 483-489
    • Coffin, J.1
  • 8
    • 0032577444 scopus 로고    scopus 로고
    • HIV-1 auxiliary proteins: Making connections in a dying cell
    • Cullen B. R. HIV-1 auxiliary proteins: making connections in a dying cell. Cell. 93:1998;685-692.
    • (1998) Cell , vol.93 , pp. 685-692
    • Cullen, B.R.1
  • 10
    • 0032546817 scopus 로고    scopus 로고
    • HIV-1 regulatory/accessory genes: Keys to unraveling viral and host cell biology
    • Emerman M., Malim M. H. HIV-1 regulatory/accessory genes: keys to unraveling viral and host cell biology. Science. 280:1998;1880-1884.
    • (1998) Science , vol.280 , pp. 1880-1884
    • Emerman, M.1    Malim, M.H.2
  • 12
    • 0032554629 scopus 로고    scopus 로고
    • Backbone cyclic peptide, which mimics the Nuclear Localization Signal of HIV-1 MA, inhibits nuclear import and virus production in non-dividing cells
    • Friedler A., Zakai N., Karni O., Broder Y. C., Baraz L., Kotler M., Loyter A., Gilon C. Backbone cyclic peptide, which mimics the Nuclear Localization Signal of HIV-1 MA, inhibits nuclear import and virus production in non-dividing cells. Biochemistry. 37:1998;5616-5622.
    • (1998) Biochemistry , vol.37 , pp. 5616-5622
    • Friedler, A.1    Zakai, N.2    Karni, O.3    Broder, Y.C.4    Baraz, L.5    Kotler, M.6    Loyter, A.7    Gilon, C.8
  • 13
    • 0026155124 scopus 로고
    • Backbone cyclization: A new method for conferring conformational constraint on peptides
    • Gilon C., Halle D., Chorev M., Selinger Z., Byk G. Backbone cyclization: a new method for conferring conformational constraint on peptides. Biopolymers. 31:1991;745-750.
    • (1991) Biopolymers , vol.31 , pp. 745-750
    • Gilon, C.1    Halle, D.2    Chorev, M.3    Selinger, Z.4    Byk, G.5
  • 15
    • 0027953516 scopus 로고
    • Subcellular localization of the vif protein of human immunodeficiency virus type 1
    • Goncalves J., Jallepalli P., Gabuzda D. H. Subcellular localization of the vif protein of human immunodeficiency virus type 1. J. Virol. 68:1994;704-712.
    • (1994) J. Virol. , vol.68 , pp. 704-712
    • Goncalves, J.1    Jallepalli, P.2    Gabuzda, D.H.3
  • 16
    • 0001241103 scopus 로고    scopus 로고
    • Cyclic HIV protease inhibitors: Design and synthesis of orally bioavailable, pyrazole p2/p2′ cyclic ureas with improved potency
    • Han Q., Chang C. H., Li R., Ru Y., Jadhav P. K., Lam P. Y. S. Cyclic HIV protease inhibitors: design and synthesis of orally bioavailable, pyrazole p2/p2′ cyclic ureas with improved potency. J. Med. Chem. 41:1998;2019-2028.
    • (1998) J. Med. Chem. , vol.41 , pp. 2019-2028
    • Han, Q.1    Chang, C.H.2    Li, R.3    Ru, Y.4    Jadhav, P.K.5    Lam, P.Y.S.6
  • 17
    • 0031821459 scopus 로고    scopus 로고
    • Nelfinavir: A review of its therapeutic efficacy in HIV infection
    • Jarvis B., Faulds D. Nelfinavir: a review of its therapeutic efficacy in HIV infection. Drugs. 56:1998;147-167.
    • (1998) Drugs , vol.56 , pp. 147-167
    • Jarvis, B.1    Faulds, D.2
  • 19
    • 0029943637 scopus 로고    scopus 로고
    • Design and synthesis of substrate-based peptidomimetic human immunodeficiency virus protease inhibitors containing the hydroxymethylcarbonyl isostere
    • Kiso Y. Design and synthesis of substrate-based peptidomimetic human immunodeficiency virus protease inhibitors containing the hydroxymethylcarbonyl isostere. Biopolymers. 40:1996;235-244.
    • (1996) Biopolymers , vol.40 , pp. 235-244
    • Kiso, Y.1
  • 20
    • 0032537482 scopus 로고    scopus 로고
    • Resistance to HIV protease inhibitors: A comparison of enzyme inhibition and antiviral potency
    • Klabe R. M., Bacheler L. T., Ala P. J., Erickson-Viitanen S., Meek J. L. Resistance to HIV protease inhibitors: a comparison of enzyme inhibition and antiviral potency. Biochemistry. 37:1998;8735-8742.
    • (1998) Biochemistry , vol.37 , pp. 8735-8742
    • Klabe, R.M.1    Bacheler, L.T.2    Ala, P.J.3    Erickson-Viitanen, S.4    Meek, J.L.5
  • 21
  • 22
    • 0026757343 scopus 로고
    • HIV-1 Gag-protease fusion proteins are enzymatically active
    • Kotler M., Arad G., Huges S. H. HIV-1 Gag-protease fusion proteins are enzymatically active. J. Virol. 66:1992;6781-6783.
    • (1992) J. Virol. , vol.66 , pp. 6781-6783
    • Kotler, M.1    Arad, G.2    Huges, S.H.3
  • 24
    • 0029840569 scopus 로고    scopus 로고
    • Ritonavir
    • Lea A. P., Faulds D. Ritonavir. Drugs. 52:1996;541-546.
    • (1996) Drugs , vol.52 , pp. 541-546
    • Lea, A.P.1    Faulds, D.2
  • 25
    • 0028805216 scopus 로고
    • The vif protein of human and simian immunodeficiency viruses is packaged into virions and associates with viral core structures
    • Liu H., Wu X., Newman M., Shaw G., Hahn B., Kappes J. The vif protein of human and simian immunodeficiency viruses is packaged into virions and associates with viral core structures. J. Virol. 69:1995;7630-7638.
    • (1995) J. Virol. , vol.69 , pp. 7630-7638
    • Liu, H.1    Wu, X.2    Newman, M.3    Shaw, G.4    Hahn, B.5    Kappes, J.6
  • 26
    • 0025099455 scopus 로고
    • Novel fluorogenic substrates for assaying retroviral proteases by resonance energy transfer
    • Matayoshi E. D., Wang G. T., Krafft G. A., Erickson J. Novel fluorogenic substrates for assaying retroviral proteases by resonance energy transfer. Science. 247:1990;954-958.
    • (1990) Science , vol.247 , pp. 954-958
    • Matayoshi, E.D.1    Wang, G.T.2    Krafft, G.A.3    Erickson, J.4
  • 27
    • 0031003928 scopus 로고    scopus 로고
    • HIV accessory proeins as therapeutic targets
    • Miller R. H., Sarver N. HIV accessory proeins as therapeutic targets. Nature Med. 3:1997;389-394.
    • (1997) Nature Med. , vol.3 , pp. 389-394
    • Miller, R.H.1    Sarver, N.2
  • 31
    • 0002881829 scopus 로고    scopus 로고
    • Mimicking extended conformations of protease substrates: Designing cyclic peptidomimetics to inhibit HIV-1 protease
    • Reid R. C., Fairlie D. P. Mimicking extended conformations of protease substrates: designing cyclic peptidomimetics to inhibit HIV-1 protease. Advan. Amino Acid Mimetics Peptidomimetics. 1:1997;77-107.
    • (1997) Advan. Amino Acid Mimetics Peptidomimetics , vol.1 , pp. 77-107
    • Reid, R.C.1    Fairlie, D.P.2
  • 33
    • 0029863567 scopus 로고    scopus 로고
    • Inhibition and catalytic mechanism of HIV-1 aspartic protease
    • Silva A. M., Cachau R. E., Sham H. L., Erickson J. W. Inhibition and catalytic mechanism of HIV-1 aspartic protease. J. Mol. Biol. 255:1996;321-346.
    • (1996) J. Mol. Biol. , vol.255 , pp. 321-346
    • Silva, A.M.1    Cachau, R.E.2    Sham, H.L.3    Erickson, J.W.4
  • 34
    • 0029056704 scopus 로고
    • Aberrant Gag protein composition of human immunodeficiency virus type 1 vif mutants produced in lymphocytes
    • Simm M., Shahabuddin M., Chao W., Allan J. S., Volsky D. J. Aberrant Gag protein composition of human immunodeficiency virus type 1 vif mutants produced in lymphocytes. J. Virol. 69:1995;4582-4586.
    • (1995) J. Virol. , vol.69 , pp. 4582-4586
    • Simm, M.1    Shahabuddin, M.2    Chao, W.3    Allan, J.S.4    Volsky, D.J.5
  • 35
    • 0001903028 scopus 로고
    • The complexities of AIDS: An assessment of the HIV protease as a therapeutic target
    • Tomasselli A. G., Howe W. J., Sawyer T. K., Wlodawer A., Heinrikson R. L. The complexities of AIDS: an assessment of the HIV protease as a therapeutic target. Chim. Oggi. 5:1991;6-27.
    • (1991) Chim. Oggi , vol.5 , pp. 6-27
    • Tomasselli, A.G.1    Howe, W.J.2    Sawyer, T.K.3    Wlodawer, A.4    Heinrikson, R.L.5
  • 36
    • 0029150052 scopus 로고
    • HIV accessory proteins: Leading roles for the supporting cast
    • Trono D. HIV accessory proteins: leading roles for the supporting cast. Cell. 82:1995;189-192.
    • (1995) Cell , vol.82 , pp. 189-192
    • Trono, D.1
  • 37
    • 0027179103 scopus 로고
    • Vif is crucial for HIV-1 provural DNA synthesis in infected cells
    • Von-Schwedler U., Song J., Aiken C., Trono D. Vif is crucial for HIV-1 provural DNA synthesis in infected cells. J. Virol. 67:1993;4945-4955.
    • (1993) J. Virol. , vol.67 , pp. 4945-4955
    • Von-Schwedler, U.1    Song, J.2    Aiken, C.3    Trono, D.4
  • 39
    • 0028986487 scopus 로고
    • Targeting HIV-1 protease: A test of drug-design methodologies
    • West M. L., Fairlie D. P. Targeting HIV-1 protease: a test of drug-design methodologies. Trends Pharm. Sci. 16:1995;67-75.
    • (1995) Trends Pharm. Sci. , vol.16 , pp. 67-75
    • West, M.L.1    Fairlie, D.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.