Chemicals in diesel exhaust particles generate reactive oxygen radicals and induce apoptosis in macrophages

Journal of Immunology

Volumn 163, Issue 10, 1999, Pages 5582-5591

  Hiura, Timothy S ^a   Kaszubowski, Martin P ^a   Li, Ning ^a   Nel, Andre E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIESEL FUEL; OXYGEN RADICAL; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; EXHAUST GAS; IMMUNOTOXICITY; MACROPHAGE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL DEATH; CELL LINE; ENZYME ACTIVATION; FREE RADICALS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MACROPHAGES; MACROPHAGES, ALVEOLAR; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHAGOCYTOSIS; REACTIVE OXYGEN SPECIES; TUMOR CELLS, CULTURED; VEHICLE EMISSIONS;

EID: 0033571350     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. Nel, A. E., D. Diaz-Sanchez, D. Ng, T. Hiura, and A. Saxon. 1998. Enhancement of allergic inflammation by the interaction between diesel exhaust particles and the immune system. J. Allergy Clin. Immunol. 102:539.
2. Peterson, B., and A. Saxon. 1996. Global increases in allergic respiratory disease: the possible role of diesel exhaust particles. Ann. Allergy Asthma Immunol. 77: 263.
3. Diaz-Sanchez, D., A. R. Dotson, H. Takenaka, and A. Saxon. 1994. Diesel exhaust particles induce local IgE production in vivo and alter the pattern of IgE messenger RNA isoforms. J. Clin. Invest. 94:1417.
4. Diaz-Sanchez, D. 1997. The role of diesel exhaust particles and their associated polyaromatic hydrocarbons in the induction of allergic airway disease. Allergy 52:52.
5. Li, X. Y., P. S. Gilmour, K. Donaldson, and W. MacNee. 1996. Free radical activity and pro-inflammatory effects of particulate air pollution (PM10) in vivo and in vitro. Thorax 51:1216.
6. Fleming, D. M., and D. L. Crombie. 1987. Prevalence of asthma and hay fever in England and Wales. Br. Med. J. 294:279.
7. Aberg, N. 1989. Asthma and allergic rhinitis in Swedish conscripts. Clin. Exp. Allergy 19:59.
8. Burney, P. J. 1988. Asthma death in England and Wales 1931-1985: evidence for true increase in asthma mortality. J. Epidemiol. Community Health 42:316.
9. Haahtela, T., H. Lindholm, F. Bjorksten, K. Koskenvuo, and L. A. Laitinen. 1990. Prevalence of asthma in Finnish young men. Br. Med. J. 301:266.
10. Yunginger, J. W., R. C. Reed, and E. J. O'Connell. 1992. A community based study of the epidemiology of asthma. Am. Rev. Respir. Dis. 146:888.
11. Miyamoto, T. 1997. Epidemiology of pollution-induced airway disease in Japan. Allergy 52(Suppl. 38):30.
12. Anonymous. 1998. Forecasted state-specific estimates of self-reported asthma prevalence-United States. Morbid. Mortality Wkly. Rep. 47:1022.
13. 2-type pattern. J. Immunol. 158:2406.
14. Diaz-Sanchez, D., A. Tsien, A. Casillas, A. R. Dotson, and A. Saxon. 1996. Enhanced nasal cytokine production in human beings after in vivo challenge with diesel exhaust particles. J. Allergy Clin. Immunol. 98:114.
15. Muranaka, M., S. Suzuki, K. Koizumi, S. Takafuji, T. Miyamoto, R. Ikemori, and H. Tokiwa. 1986. Adjuvant activity of diesel exhaust particulates for the production of IgE antibody in mice. J. Allergy Clin. Immunol. 77:616.
16. Fujimaki, H., O. Nohara, T. Ichinse, N. Watanabe, and S. Saito. 1994. IL-4 production in mediastinal lymph node cells in mice intratracheally instilled with diesel exhaust particulates and antigen. Toxicology 92:261.
17. Fujimaki, H., K. Saneyoshi, F. Shiraishi, T. Imai, and T. Endo. 1997. Inhalation of diesel exhaust enhances antigen-specific IgE antibody production in mice. Toxicology 116:227.
18. Miyabara, Y., H. Takano, T. Ichinose, H. Lim, and M. Sagai. 1998. Diesel exhaust enhances allergic airway inflammation and hyperresponsiveness in mice. Am. J. Respir. Crit. Care Med. 157:1.
19. Takano, H., T. Yoshikawa, T. Ichinose, Y. Miyabara, K. Imaoka, and M. Sagai. 1997. Diesel exhaust particles enhance antigen-induced airway inflammation and local cytokine expression in mice. Am. J. Respir. Crit. Care Med. 156:36.
20. Bates, D., C. Pope, M. Thun, M. Namboodiri, D. Dockery, J. Evans, F. Speizer, and C. Heath. 1995. Particulate air pollution as a predictor of mortality in a prospective cohort study of US adults. Am. J. Respir. Crit. Care Med. 151:669.
21. Wordley, J., S. Walters, and J. G. Ayres. 1997. Short term variations in hospital admissions and mortality and particulate air pollution. Occup. Environ. Med. 54:108.
22. Barfknecht, T. R., R. A. Hites, E. L. Cavaliers, and W. G. Thilly. 1982. Human cell mutagenicity of polycyclic aromatic hydrocarbon components of diesel emissions. Dev. Toxicol. Environ. Sci. 10:277.
23. Takenaka, H., K. Zhang, D. Diaz-Sanchez, A. Tsien, and A. Saxon. 1995. Enhanced human IgE results from exposure to the aromatic hydrocarbons in diesel exhaust: diesel effects on B cell IgE productions. J. Allergy Clin. Immunol. 95: 103.
24. Ng, D., N. Kokot, T. Hiura, M. Faris, A. Saxon, and A. Nel. 1998. Macrophage activation by polycyclic aromatic hydrocarbons: evidence for the involvement of stress-activated protein kinases, AP-1 and anti-oxidant response element. J. Immunol. 161:942.
25. Terada, N., K. Maesako, K. Hiruma, N. Hamano, G. Houki, A. Konno, T. Ikeda, and M. Sai. 1997. Diesel exhaust particulates enhance eosinophil adhesion to nasal epithelial cells and cause degranulation. Int. Arch. Allergy Immunol. 114: 167.
26. Yang, H. M., J. Y. C. Ma, V. Castranova, and J. K. H. Ma. 1997. Effects of diesel exhaust particles on the release of interleukin-1 and tumor necrosis factor-α from rat alveolar macrophages. Exp. Lung Res. 23:269.
27. Bayram, H., J. L. Devalia, R. J. Sapsford, T. Ohtoshi, Y. Miyabara, M. Sagai, and R. J. Davies. 1998. The effect of diesel exhaust particles on cell function and release of inflammatory mediators from human bronchial epithelial cells in vitro. Am. J. Respir. Cell. Mol. Biol. 18:441.
28. Li, H., C. D. Banner, G. G. Mason, R. N. Westerholm, and J. J. Rafter. 1996. Determination of polycyclic aromatic compounds and dioxin receptor ligands present in diesel exhaust particulate extracts. Atmospheric Environ. 30:3537.
29. Casellas, M., P. Fernandez, J. M. Bayona, and A. M. Solanas. 1995. Bioassay-directed chemical analysis of genotoxic components in urban airborne particulate matter from Barcelona (Spain). Chemosphere 30:725.
30. Clunies-Ross, C., B. R. Stanmore, and G. J. Millar. 1996. Dioxins in diesel exhaust. Nature 381:379.
31. Ichinose, T., Y. Yajima, M. Nagashima, S. Takenoshita, Y. Nagamachi, and M. Sagai. 1997. Lung carcinogenesis and formation of 8-hydroxy-deoxyguanosine in mice by diesel exhaust particles. Carcinogenesis 18:185.
32. Park, J. Y. K., M. K. Shigenaga, and B. N. Ames. 1996. Induction of cytochrome P4501A1 by 2,3,7,8-tetrachlorodibenxo-p-dioxin or indolo(3,2-b)carbazole is associated with oxidative DNA damage. Proc. Natl. Acad. Sci. USA 93:2322.
33. Pinkus, R., L. M. Weiner, and V. Daniel. 1996. Role of oxidants and antioxidants in the induction of AP-1, NF-κB, and glutathione S-transferase gene expression. J. Biol. Chem. 271:13422.
34. Kumagai, Y., T. Arimoto, M. Shinyashiki, N. Shimojo, Y. Nakai, T. Yoshikawa, and M. Sagai. 1997. Generation of reactive oxygen species during interaction of diesel exhaust particle components with NADPH-cytochrome p450 reductase and involvement of the bioactivation in the DNA damage. Free Radical Biol. Med. 22:479.
35. Marshall, M. V., T. L. McLemore, R. R. Martin, N. P. Wray, D. L. Busbee, E. T. Cantrell, M. S. Arnott, and A. C. Griffin. 1979. Benzo(a)pyrene activation and detoxification by human pulmonary alveolar macrophages and lymphocytes. In Polynuclear Aromatic Hydrocarbons: Chemistry and Biological Effects. Eds. A. Bjorseth and A. J. Dennis. Battelle Press, p. 299.
36. McLemore, T. L., R. R. Martin, K. L. Toppell, D. L. Busbee, and E. T. Cantrell. 1977. Comparison of aryl hydrocarbon hydroxylase in cultured blood lymphocytes and pulmonary macrophages. J. Clin. Invest. 60:1017.
37. McLemore, T. L., G. A. Warr, and R. R. Martin. 1977. Induction of aryl hydrocarbon hydroxylase in human pulmonary macrophages by benzanthracene. Cancer Lett. 2:327.
38. Harris, C. C., I. C. Hsu, G. D. Stoner, B. F. Trump, and J. K. Selkirk. 1978. Human pulmonary alveolar macrophages metabolize benzo(a)pyrene to proximate and ultimate mutagens. Nature 272:633.
39. Stohs, S. J., and M. Bacchi. 1993. In vitro induction of reactive oxygen species by 2,3,7,8-tetrachlorodibenzo-p-dioxin, endrin and lindane in rat peritoneal macrophages, and hepatic mitochondria and microsomes. Free Radical Biol. Med. 14:11.
40. Whitlock, J. P., S. T. Okino, L. Dong, H. P. Ko, R. Clarke-Katzenberg, Q. Ma, and H. Li. 1996. Induction of cytochrome P4501A1: a model for analyzing mammalian gene transcription. FASEB J. 10:809.
41. Hiura, T. S., S. J. Kempiak, and A. E. Nel. 1999. Activation of the human RANTES gene promoter in a macrophage cell line by lipopolysaccharide dependent on stress-activated protein kinases and the IκB kinase cascade: implications for exacerbation of allergic inflammation by environmental pollutants. Clin. Immunol. 20:287.
42. Hossain, A., S. Tsuchiya, M. Minegishi, M. Osada, S. Ikawa, F. A. Tezuk, M. Kaji, T. Konno, M. Watanabe, and H. Kikuchi. 1998. The Ah receptor is not involved in 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated apoptosis in human leukemic T cell lines. J. Biol. Chem. 273:19853.
43. 2-terminal kinase 1 by benzo(a)pyrene. Cancer Res. 58:2102.
44. Hahon, N., J. A. Booth, F. Green, and T. R. Lewis. 1985. Influenza virus infection in mice after exposure to coal dust and diesel engine emissions. Environ. Res. 37:44.
45. Druihle, A., B. Wallaert, A. Tsicopoulos, J. Lapa e Silva, I. Tillie-Leblond, A. Tonnel, and M. Pretolani. 1998. Apoptosis, proliferation, and expression of Bcl-2, Fas, and Fas ligand in bronchial biopsies from asthmatics. Am. J. Respir. Cell. Mol. Biol. 19:747.
46. Grashoff, W. F., J. K. Sont, P. J. Sterk, P. S. Hiemstra, W. I. de Boer, J. Stolk, J. Han, and J. M. Van Krieken. 1997. Chronic obstructive pulmonary disease: role of bronchiolar mast cells and macrophages. Am. J. Pathol. 151:1785.
47. Onodera, S., K. Suzuki, T. Matsuno, K. Kaneda, M. Takagi, and J. Nishihira. 1997. Macrophage migration inhibitory factor induces phagocytosis of foreign particles by macrophages in autocrine and paracrine fashion. Immunology 92: 131.
48. Yang, H., Y. C. Ma, V. Castranova, and J. K. H. Ma. 1997. Effects of diesel exhaust particles on the release of interleukin-1 and tumor necrosis factor-α from rat alveolar macrophages. Exp. Lung Res. 23:269.
49. Boersma, A.W., K. Nooter, R. G. Oostrum, and G. Stoter. 1996. Quantification of apoptotic cells with fluorescein isothiocyanate-labeled annexin V in Chinese hamster ovary cell cultures treated with cisplatin. Cytometry 24:123.
50. Thornberry, N. A., and Y. Lazebnik. 1998. Caspases: enemies within. Science 281:1312.
51. Susin, S. A., N. Zamsani, and G. Kroemer. 1998. Mitochondria as regulators of apoptosis: doubt no more. Biochim. Biophys. Acta. 1366:151.
52. Ashkenazi, A., and V. M. Dixit. 1998. Death receptors: signaling and modulation. Science 281:1305.
53. 2 in cultured endothelial cells probes. Arch. Biochem. Biophys. 302:348.
54. Cross, A. R., and O. T. Jones. 1991. Enzymatic mechanisms of superoxide production. Biochim. Biophys. Acta 1057:281.
55. Goldsmith, C.-A. W., A. Imrich, H. Danaee, Y. Y. Ning, and L. Kobzik. 1998. Analysis of air pollution particulate-mediated oxidant stress in alveolar macrophages. J. Toxicol. Environ. Health. 54:529.
56. Mayer, M., and M. Noble. 1994. N-acelyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro. Proc. Natl. Acad. Sci. USA 91:7496.
57. Faris, M., K. M. Latinas, S. J. Kempiak, G. A. Koretzky, and A. E. Nel. 1998. Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter. Mol. Cell. Biol. 18:5414.
58. Ishizuka, T., N. Terada, P. Gerwins, E. Hamelmann, A. Oshiba, G. R. Fanger, G. L. Johnson, and E. W. Gelfand. 1997. Mast cell tumor necrosis factor α production is regulated by MEK kinases. Proc. Natl. Acad. Sci. USA 94:6358.
59. Sagai, M., A. Furuyama, and T. Ichinose. 1996. Biological effects of diesel exhaust particles (DEP). III. Pathogenesis of asthma like symptoms in mice. Free Radical Biol. Med. 21:199.