High incidence of chromosomal imbalances and gene amplifications in the classical follicular variant of follicle center lymphoma

Blood

Volumn 88, Issue 4, 1996, Pages 1437-1444

  Bentz, Martin ^a   Werner, Claudius A ^b   Döhner, Hartmut ^b   Joos, Stefan ^b   Barth, Thomas F E ^b   Siebert, Reiner ^b   Schröder, Martin ^b   Stilgenbauer, Stephan ^b   Fischer, Konstanze ^b   Möller, Peter ^b   Lichter, Peter ^b  

^a Medizinische Klinik und Poliklinik V   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ADULT; AGED; ARTICLE; CHROMOSOME 12; CHROMOSOME 18; CHROMOSOME 7; CHROMOSOME 8; CHROMOSOME TRANSLOCATION; CLINICAL ARTICLE; CYTOGENETICS; DNA HYBRIDIZATION; DNA PROBE; FEMALE; GENE AMPLIFICATION; GENOME; HUMAN; HUMAN TISSUE; MALE; NONHODGKIN LYMPHOMA; ONCOGENE MYC; PRIORITY JOURNAL; SOUTHERN BLOTTING; X CHROMOSOME;

EID: 9444227674     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.4.1437.bloodjournal8841437     Document Type: Article

References (38)

1. Brill NE, Baehr G. Rosenthal N: Generalized giant lymph follicle hyperplasia of lymph nodes and spleen. A hitherto undescribed disease. JAMA 84:668, 1925
2. Symmers D: Follicular lymphadenopathy with splenomegaly. A newly recognized disease of the lymphatic system. Arch Pathol 3:816, 1927
3. Harris NL, Jaffe ES, Stein H, Banks PM, Chan JKC, Cleary ML, Delsol G, De Wolf-Peeters C, Falini B, Gatter KC, Grogan TM, Isaacson PG, Knowles DM, Mason DY, Müller-Hermelink H-K, Pileri SA, Pins MA, Ralfkiaer E, Warnke RA: A revised European-American classification of lymphoid neoplasms: A proposal from the International Lymphoma Study Group. Blood 84:1361, 1994
4. Warnke RA, Weiss LM, Chan JKC, Cleary ML, Dorfman RF: Tumors of the Lymph Nodes and Spleen. Washington, DC, Armed Forces Institute of Pathology, 1995.
5. Yunis JJ, Frizzera G, Oken MM, McKenna J, Theologidcs A, Arnesen M: Multiple recurrent genomic defects in follicular lymphoma - A possible model for cancer. N Engl J Med 316:79, 1987
6. McDonnell TJ, Deane N, Platt FM, Nunez G, Jaeger U, McKearn JP, Korsmeyer SJ: BCL-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation. Cell 57:79, 1989
7. Hockenberry D, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ: BCL-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334, 1990
8. McDonnell TJ, Korsmeyer SJ: Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14;18). Nature 349:254, 1991
9. Tilly H, Rossi A, Stamatoullas A, Lenormand B, Bigorgne C, Kunlin A, Monconduit M, Bastard C: Prognostic value of chromosome abnormalities in follicuiar lymphoma. Blood 84:1043, 1994
10. Autio K, Elonen E, Teerenhovi L, Knuutila S: Cytogenetic and immunologic characterization of mitotic cells in chronic lymphocytic leukemia. Eur J Haematol 39:289, 1987
11. Bentz M, Huck K, du Manoir S, Joos S, Werner CA, Fischer K, Donner H, Lichter P: Comparative genomic hybridization in chronic B-cell leukemias reveals a high incidence of chromosomal gains and losses. Blood 85:3610, 1995
12. Le Beau MM: Detecting genetic changes in human tumor cells: Have scientists "gone fishing?" Blood 81:1979, 1993
13. Bentz M, Döhner H, Cabot G, Lichter P: Fluorescence in situ hybridization in leukemias: The FISH are spawning! Leukemia 8:1447, 1994
14. Kallioniemi A, Kallioniemi O-P, Sudar D, Rutovitz D, Gray JW, Waldman F, Pinkel D: Comparative genomic hybridization for molecular cylogenetic analysis of solid tumors. Science 258:818, 1992
15. Du Manoir S, Speicher MR, Joos S, Schröck E, Popp S, Döhner H, Kovacs G, Robert-Nicoud M, Lichter P, Cremer T: Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization. Hum Genet 90:590, 1993
16. Joos S, Scherthan H, Speicher MR, Schlegel J, Cremer T, Lichter P: Detection of amplified genomic sequences by reverse chromosome painting using genomic tumor DNA as probe. Hum Genet 90:584, 1993
17. Sambrook J, Frisch EF, Maniatis T (eds): Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory, 1989
18. Lichter P, Bentz M, Du Manoir S, Joos S: Comparative genomic hybridization, in Verma R, Babu A (eds): Human Chromosomes. New York, NY, McGraw-Hill, 1995
19. Bentz M, Döhner H, Huck K, Schütz B, Ganser A, Joos S, Du Manoir S, Lichter P: Comparative genomic hybridization in the investigation of myeloid leukemias. Genes Chromosom Cancer 12:193, 1995
20. Du Manoir S, Schröck E, Bentz M, Speicher MR, Joos S, Ried T, Lichter P, Cremer T: Quantitative analysis of comparative genomic hybridization. Cytometry 19:27, 1995
21. Schröck E, Thiel G, Lozanova T, Du Manoir S, Meffert M-C, Jauch A, Speicher MR, Nürnberg P, Vogel S, Jänisch W, Donis-Keller H, Ried T, Witkowski R, Cremer T: Comparative genomic hybridization of human malignant gliomas reveals multiple amplification sites and nonrandom chromosomal gains and losses. Am J Pathol 144:1203, 1994
22. Dreyling MH, Bohlander SK, Adeanju MO, Olopade OL: Detection of CDKN2 deletions in tumor cell lines and primary gliomas by interphase fluorescence in situ hybridization. Cancer Res 55:984, 1995
23. Joos S, Falk M, Lichter P, Haluska FG, Henglein B, Lenoir GM, Bornkamm GW: Variable breakpoints in Burkitt lymphoma cells with chromosomal t(8; 14) translocation separate c-myc and the IgH locus up to several hundred kb. Hum Mol Genet 1:625, 1992.
24. Hopman AHN, Poddighe P, Moesker O, Ramaekers FCS: Interphase cytogenetics: An approach to the detection of genetic aberrations in tumors, in Herrington M, McGee A (eds): Diagnostic Molecular Pathology. A Practical Approach. New York, NY, IRL, 1992
25. Lichter P, Umeda PK, Levin JE, Vosberg H-P: Partial characterization of the human β-myosin heavy chain gene which is expressed in heart and skeletal muscle. Eur J Biochem 160:419, 1986
26. Liu Y, Hernandez AM, Shibata D: BCL2 translocation frequency rises with age in humans. Proc Natl Acad Sci USA 91:8910, 1994
27. Limpens J, Stad R, Vos C, de Vlaam C, de Jong D, van Ommen G-JB, Schuuring E, Kluin P: Lymphoma-associated translocation t(14;18) in blood B cells of normal individuals. Blood 85:2528, 1995
28. Mitelman F: Catalog of Chromosome Aberrations in Cancer. New York, NY, Wiley-Liss, 1994
29. Johansson B, Mertens F, Mitelman F: Cytogenetic evolution patterns in Non-Hodgkin's Lymphomas. Blood 86:3905, 1995
30. Isola J, DeVries S, Chu L, Ghazvini S, Waldman F: Analysis of changes in DNA sequence copy number by comparative genomic hybridization in archival paraffin-embedded tumor samples. Am J Pathol 145:1301, 1994
31. Speicher M, Prescher G, Du Manoir S, Jauch A, Horsthemke B, Bornfeld N, Becher R, Cremer T: Chromosomal gains and losses in uveal melanomas detected by comparative genomic hybridization. Cancer Res 54:3817, 1994
32. Kallioniemi A, Kallioniemi OP, Piper J, Tanner M, Stokke T, Chen L, Smith HS, Pinkel D, Gray JW, Waldman FM: Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. Proc Natl Acad Sci USA 91:2156, 1994
33. Joos S, Bergerheim USR, Pan Y, Matsuyama H, Bentz M, Du Manoir S, Lichter P: Mapping of chromosomal gains and losses in prostate cancer by comparative genomic hybridization. Genes Chromosom Cancer 14:267, 1995
34. GDB™ Human Genome Database [database online]. Baltimore, MD: Johns Hopkins University, 1990-. Updated daily. Available from internet: <URL:http://gdbwww.gdb.org/gdb/browser/ docs/topq.html>
35. Strasser A, Harris AW, Bath ML, Cory S: Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2. Nature 348:331, 1990
36. Joos S, Otano-Joos MI, Ziegler S, Brüderlein S, Du Manoir S, Bentz M, Möller P, Lichter P: Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and the REL gene. Blood 87:1571, 1996
37. Houldsworth D, Mathew S, Rao PH, Dyomina K, Louie DC, Parsa N, Offit K, Chaganti RSK: Rel proto-oncogene is frequently amplified in extranodal diffuse large cell lymphoma. Blood 87:25, 1996
38. Mitelman F (ed): ISCN (1995): An international system for human cytogenetic nomenclature. Basel, Switzerland, Karger, 1995