Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptors

Molecular and Cellular Biology

Volumn 16, Issue 6, 1996, Pages 2594-2605

  Imhof, Markus O ^a   McDonnell, Donald P ^a  

^a DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID RECEPTOR; PROGESTERONE RECEPTOR;

ARTICLE; HORMONAL REGULATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION;

EUKARYOTA; MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 0029953663     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.6.2594     Document Type: Article

References (88)

1. Altschul, S. F., W. Gish, W. Miller, E. W. Myers, and D. J. Lipman. 1990. Basic local alignment search tool. J. Mol. Biol. 215:403-410.
2. Arany, Z., W. R. Sellers, D. M. Livingston, and R, Eckner. 1994. E1A-associated p300 and CREB-associated CBP belong to a conserved family of coactivators. Cell 77:799-800.
3. Berger, S., B. Piña, N. Silverman, G. A. Marcus, J. Agapite, J. L. Regier, S. J. Triezenberg, and L. Guarente. 1992. Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains. Cell 70:251-265.
4. Bork, P., and M. Sudol. 1994. The WW domain: a signalling site in dystrophin? Trends Biochem. Sci. 19:531-533.
5. Cavaillès, V., S. Dauvois, P. S. Danielian, and M. G. Parker. 1994. Interaction of proteins with transcriptionally active estrogen receptors. Proc. Natl. Acad. Sci. USA 91:10009-10013.
6. Chen, H. I., and M. Sudol. 1995. The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules. Proc. Natl. Acad. Sci. USA 92:7819-7823.
7. Chen, J.-L., L. D. Attardi, C. P. Verrijzer, K. Yokoraori, and R. Tjian. 1994. Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators. Cell 79:93-105.
8. Chen, Z.. J. Hagler, V. J. Palombella, F. Melandri, D. Scherer, D. Ballard, and T. Maniatis. 1995. Signal-induced site-specific phosphorylation targets IκBα to the ubiquitin-proteasome pathway. Genes Dev. 9:1586-1597.
9. Christianson, T. W., R. S. Sikorski, M. Dante, J. H. Shero, and P. Hieter. 1992. Multifunctional yeast high-copy-number shuttle vectors. Gene 110:119-122.
10. Chrivia, J. C., R. P. S. Kwok, N. Lamb, M. Hagiwara, M. R. Montminy, and R. H. Goodman. 1993. Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature (London) 365:855-859.
11. Clechanover, A. 1994. The ubiquitin-proteasome proteolytic pathway. Cell 79:13-21.
12. Dana, S. L., P. A. Hoener, D. A. Wheeler, C. B. Lawrence, and D, P. McDonnell. 1994. Novel estrogen response elements identified by genetic selection in yeast are differentially responsive to estrogens and antiestrogens in mammalian cells. Mol. Endocrinol. 8:1193-1207.
13. Desaintes, C., S. Hallez, P. Van Alphen, and A. Burny. 1992. Transcriptional activation of several heterologous promoters by the E6 protein of human papillomavirus type 16. J. Virol. 66:325-333.
14. Douglass, J., C. T. McMurray, J. E. Garrett, J. P. Adelman, and L. Calavetta. 1989. Characterization of the rat prodynorphin gene. Mol. Endocrinol. 3:2070-2078.
15. Eisenmann, D. M., K. M. Arndt, S. L. Ricupero, J. W. Rooney, and F. Winston. 1992. SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae. Genes Dev. 6:1319-1331.
16. Evans, R. M. 1988. The steroid and thyroid hormone receptor superfamily. Science 240:889-895.
17. Fuller, P. J. 1991. The steroid receptor superfamily: mechanisms of diversity. FASEB J. 5:3092-3099.
18. Garabedian, M. J., and K. R. Yamamoto. 1992. Genetic dissection of the signaling domain of a mammalian steroid receptor in yeast. Mol. Biol. Cell 3:1245-1257.
19. Ge, H., and R. G. Roeder. 1994. Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes. Cell 78:513-523.
20. Gstaiger, M., L. Knoepfel, O. Georglev, W. Schaffner, and C. M. Hovens. 1995. A B-cell coactivator of octamer-binding transcription factors. Nature (London) 373:360-362.
21. Gu, J., K. Ren, R. Dubner, and M. J. Iadarola. 1994. Cloning of a DNA binding protein that is a tyrosine kinase substrate and recognizes an upstream initiator-like sequence in the promoter of the preprodynorphin gene. Mol. Brain Res. 24:77-88.
22. Gunning, P., J. Leavitt, G. Muscat, S.-Y. Ng, and L. Kedes. 1987. A human β-actin expression vector system directs high-level accumulation of antisense transcripts. Proc. Natl. Acad. Sci. USA 84:4831-4835.
23. Halachmi, S., E. Marden, G. Martin, H. MacKay, C. Abbondanza, and M. Brown. 1994. Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription. Science 264:1455-1458.
24. Haviv, I., D. Vaizel, and Y. Shaul. 1995. The X protein of hepatitis B virus coactivatcs potent activation domains. Mol. Cell. Biol. 15:1079-1085.
25. Hochstrasser, M. 1995. Ubiquitin, proteasomes, and the regulation of intracellular protein degradation. Curr. Opin. Cell Biol. 7:215-223.
26. Hoeck, W., P. Hofer, and B. Groner. 1992. Overexpression of the glucocorticoid receptor represses transcription from hormone responsive and nonresponsive promoters. J. Steroid Biochem. Mol. Biol. 41:283-289.
27. Hofmann, K., and P. Bucher. 1995. The rsp5-domain is shared by proteins of diverse functions. FEBS Lett. 358:153-157.
28. Hug, H., and T. F. Sarre. 1993. Protein kinase C isoenzymes: divergence in signal transduction? Biochem. J. 291:329-343.
29. Huibregtse, J. M., M. Scheffner, S. Beaudenon, and P. M. Howley. 1995. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc. Natl. Acad. Sci. USA 92:2563-2567. (Correction, 92:5249.)
30. Huibregtse, J. M., M. Scheffner, and P. M. Howley. 1993. Cloning and expression of the cDNA For E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. Mol. Cell. Biol. 13:775-784.
31. Huibregtse, J. M., M. Scheffner, and P. M. Howley. 1993. Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53. and ubiquitination of associated proteins. Mol. Cell. Biol. 13:4918-4927.
32. 31a.Imhof, M. O., and D. P. McDonnell. Unpublished results.
33. 31b.Imhof, M. O., and D. Su, and D. P. McDonnell. Unpublished results.
34. Ing, N., J. Beekman, S. Tsai, M.-J. Tsai, and B. O'Malley. 1992. Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II). J. Biol. Chem. 267:17617-17623.
35. II30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor. Cell 79:107-117.
36. Klein-Hitpass, L., N. L. Weigel, G. F. Allan, D. Riley, R. Rodriguez, W. T. Schrader, M.-J. Tsai, and B. W. O'Malley. 1990. The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex. Cell 60:247-257.
37. Kralli, A, S. P. Bohen, and K. R. Yamamoto. 1995. LEM1. an ATP-binding-cassette transporter, selectively modulates the biological potency of steroid hormones. Proc. Natl. Acad. Sci. USA 92:4701-4705.
38. Kretzschmar, M., K. Kaiser, F. Lottspeich, and M. Meisterernst. 1994. A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators. Cell 78:525-534.
39. Kumar, S., Y. Tomooka, and M. Noda. 1992. Identification of a set of genes with developmentally down-regulated expression in the mouse brain. Biochem. Biophys. Res. Commun. 185:1155-1161.
40. Lawrence, C. W. 1991. Classical mutagenesis techniques. Methods Enzymol. 194:273-281.
41. Le Douarin, B., C. Zechel, J.-M. Garnier, Y. Lutz, L. Tora, B. Pierrat, D. Heery, H. Gronemeyer, P. Chambon, and R. Losson. 1995. The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. EMBO J. 14:2020-2033.
42. Lee, J. W., H.-S. Choi, J. Gyuris, R. Brent, and D. D. Moore. 1995. Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. Mol. Endocrinol. 9:243-254.
43. Lewin, B. 1990. Commitment and activation at Pol II promoters: a tail of protein-protein interactions. Cell 61:1161-1164.
44. Maldonado, E., and D. Reinberg. 1995. News on initiation and elongation of transcription by RNA polymerase II. Curr. Opin. Cell Biol. 7:352-361.
45. Martin, K. J., J. W. Lillie, and M. R. Green. 1990. Evidence for interaction of different eukaryotic transcriptional activators with distinct cellular targets. Nature (London) 346:147-152.
46. Martinez, E., and W. Wahli. 1991. Characterization of hormone response elements, p. 125-153. In M. G. Parker (ed.), Nuclear hormone receptors. Academic Press, London.
47. McDonnell, D. P., D. L. Clemm, and M. O. Imhof. 1994. Definition of the cellular mechanisms which distinguish between hormone and antihormone activated steroid receptors. Semin. Cancer Biol. 5:327-336.
48. II28: three subunits of the human transcription factor TFIID. EMBO J. 14:1520-1531.
49. Metzger, D., J. H. White, and P. Chambon. 1988. The human oestrogen receptor functions in yeast. Nature (London) 334:31-36.
50. Meyer, M.-E., H. Gronemeyer, B. Turcotte, M.-T. Bocquel, D. Tasset, and P. Chambon. 1989. Steroid hormone receptors compete for factors that mediate their enhancer function. Cell 57:433-442.
51. Mitchell, P. J., and R. Tjian. 1989. Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science 245:371-378.
52. 2+-dependent manner. Mol. Brain Res. 28:29-36.
53. Muller, M., C. Baniahmad, C. Kaltschmidt, R. Schüle, and R. Renkawitz. 1991. Co-operative transactivation of steroid receptors, p. 155-174. In M. G. Parker (ed.), Nuclear hormone receptors. Academic Press, London.
54. 51a.Nomura, N. Unpublished results (GenBank accession number D42055).
55. Norris, J., D. Fan, C. Aleman, J. R. Marks, P. A. Futreal, R. W. Wiseman, J. D. Iglehart, P. L. Deininger, and D. P. McDonnell. 1995. Identification of a new subclass of Alu DNA repeats which can function as estrogen receptor-dependent transcriptional enhancers. J. Biol. Chem. 270:22777-22782.
56. Oñate, S. A., S. Y. Tsai, M.-J. Tsai, and B. W. O'Malley. 1995. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270:1354-1357.
57. Palombella, V. J., O. J. Rando, A. L. Goldberg, and T. Maniatis. 1994. The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB Cell 78:773-785.
58. Pierrat, B., D. M. Heery, P. Chambon, and R. Losson. 1994. A highly conserved region in the hormone-binding domain of the human estrogen receptor functions as an efficient transactivation domain in yeast. Gene 143:193-200.
59. Piña, B., S. Berger, G. A. Marcus, N. Silverman, J. Agapite, and L. Guarente. 1993. ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2. Mol. Cell. Biol. 13:5981-5989.
60. Poon, D., Y. Bai, A. M. Campbell, S. Bjorklund. Y.-J. Kim, S. Zhou, R. D. Kornberg, and P. A. Weil. 1995. Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 92:8224-8228.
61. Ptashne, M., and A. A. F. Gann. 1990. Activators and targets. Nature (London) 346:329-331.
62. IIs in a multisubunit complex required for activated transcription. Nature (London) 371:523-527.
63. Roberts, S. G. E., and M. R. Green. 1994. Activator-induced conformational change in general transcription factor TFIIB. Nature (London) 371:717-720.
64. Rohzyk, K., and Y. Kassir. 1992. A simple and highly efficient procedure for rescuing autonomous plasmids from yeast. Nucleic Acids Res. 20:3790.
65. Rolfe, M., P. Beer-Roraero, S. Glass, J. Eckstein, I. Berdo, A. Theodoras, M. Pagano, and G. Draetta. 1995. Reconstitution of p53-ubiquitinylation reactions from purified components: the role of human ubiquitin-conjugating enzyme UBC4 and E6-associated protein (E6AP). Proc. Natl. Acad. Sci. USA 92:3264-3268.
66. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual. 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
67. Scheffner, M., J. M. Huibregtse, and P. M. Howley. 1994. Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53. Proc. Natl. Acad. Sci. USA 91:8797-8801.
68. Scheffner, M., U. Nuber, and J. M. Huibregtse. 1995. Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade. Nature (London) 373:81-83.
69. II110 subunit of the TFIID complex. J. Biol. Chem. 270:21331-21338.
70. Sherman, F. 1991. Getting started with yeast. Methods Enzymol. 194:3-21.
71. Sikorski, R. S., and P. Hitter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27.
72. Strubin, M., J. W. Newell, and P. Matthias. 1995. OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. Cell 80:497-506.
73. Struhl, K. 1993. Yeast transcription factors. Curr. Opin. Cell Biol. 5:513-520.
74. Sudol, M., H. I. Chen, C. Bougeret, A. Einbond, and P. Bork. 1995. Characterization of a novel protein-binding module - the WW domain. FEBS Lett. 369:67-71.
75. 2+/phospholipid-binding fold. Cell 80:929-938.
76. Tassel, D., L. Tora, C. Fromental, E. Scheer, and P. Chambon. 1990. Distinct classes of transcriptional activating domains function by different mechanisms. Cell 62:1177-1187.
77. Tjian, R., and T. Maniatis. 1994. Transcriptional activation: a complex puzzle with few easy pieces. Cell 77:5-8.
78. Traeckner, E. B.-M., S. Wilk, and P. A. Baeuerle. 1994. A proteasome inhibitor prevents activation of NF-κB and stabilizes a newly phosphorylated form of IκBα that is still bound to NF-κB. EMBO J. 13:5433-5441.
79. Vegeto, E., G. F. Allan, W. T. Schrader, M.-J. Tsai, D. P. McDonnell, and B. W. O'Malley. 1992. The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor. Cell 69:703-713.
80. Verrijzer, C. P., J.-L. Chen, K. Yokomori, and R. Tjian. 1995. Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II. Cell 81:1115-1125.
81. II150: similarity to yeast gene TSM-1 and specific binding to core promoter DNA. Science 264:933-941.
82. 78a.Wagner, B., M. O. Imhof, and D. P. McDonnell. Unpublished results.
83. Wilson, A. C., K. LaMarco, M. G. Peterson, and W. Herr. 1993. The VP16 accessory protein HCF is a family of polypeptides processed from a large precursor protein. Cell 74:115-125.
84. Winston, F. 1992. Analysis of SPT genes: a genetic approach toward analysis of TFIID. histones, and other transcription factors of yeast, p. 1271-1293. In S. L. McKnight and K. R. Yamamoto (ed.), Transcriptional regulation. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
85. Winston, F., and P. L. Minehart. 1986. Analysis of the SPT3 gene and identification of its product, a positive regulator of Ty transcription. Nucleic Acids Res. 14:6885-6900.
86. Xiao, H., A. Pearson, B. Conlombe, R. Truant, S. Zhang, J. L. Regier, S. J. Triezenberg, D. Reinberg, O. Flores, C. J. Ingles, and J. Greenblatt 1994. Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53. Mol. Cell. Biol. 14:7013-7024.
87. Yu, L, P. M. Loewenstein, Z. Zhang, and M. Green. 1995. In vitro interaction of the human immunodeficiency virus type 1 Tat transactivator and the general transcription factor TFIIB with the cellular protein TAP. J. Virol. 69:3017-3023.
88. Yu, L., Z. Zhang, P. M. Loewenstein, K. Desai, Q. Tang, D. Mao, J. S. Symington, and M. Green. 1995. Molecular cloning and characterization of a cellular protein that interacts with the human immunodeficiency virus type 1 Tat transactivator and encodes a strong transcriptional activation domain. J. Virol. 69:3007-3016.