Caspase inhibition by baculovirus P35 requires interaction between the reactive site loop and the β-sheet core

Journal of Biological Chemistry

Volumn 274, Issue 37, 1999, Pages 25995-26002

  Zoog, Stephen J ^a   Bertin, John ^a,b   Friesen, Paul D ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; PROTEIN P35; UNCLASSIFIED DRUG; VIRUS ENZYME;

ARTICLE; BACULOVIRUS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME STRUCTURE; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; STOICHIOMETRY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BIOPOLYMERS; CASPASE 3; CASPASES; CYSTEINE PROTEINASE INHIBITORS; DNA PRIMERS; HYDROLYSIS; INHIBITOR OF APOPTOSIS PROTEINS; MUTAGENESIS; SPODOPTERA; SUBSTRATE SPECIFICITY; VIRAL PROTEINS;

DNA VIRUSES; UNIDENTIFIED BACULOVIRUS;

EID: 0033543616     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.37.25995     Document Type: Article

References (43)

1. Green, D. R. (1998) Cell 94, 695-698
2. Nicholson, D. W., and Thornberry, N. A. (1997) Trends Biochem. Sci. 22, 299-306
3. Cryns, V., and Yuan, J. (1998) Genes Dev. 12, 1551-1571
4. Thornberry, N. A., and Lazebnik, Y. (1998) Science 281, 1312-1316
5. Clem, R. J., Fechheimer, M., and Miller, L. K. (1991) Science 254, 1388-1390
6. Hershberger, P. A., Dickson, J. A., and Friesen, P. D. (1992) J. Virol. 66, 5525-5533
7. Bertin, J., Mendrysa, S. M., LaCount, D. J., Gaur, S., Krebs, J. F., Armstrong, R. C., Tomaselli, K. J., and Friesen, P. D. (1996) J. Virol. 70, 6251-6259
8. LaCount, D. J., and Friesen, P. D. (1997) J. Virol. 71, 1530-1537
9. Hay, B. A., Wolff, T., and Rubin, G. M. (1994) Develop. 120, 2121-2129
10. Sugimoto, A., Friesen, P. D., and Rothman, J. H. (1994) EMBO J. 13, 2023-2028
11. Rabizadeh, S., LaCount, D. J., Friesen, P. D., and Bredesen, D. E. (1993) J. Neurochem. 61, 2318-2321
12. Beidler, D. R., Tewari, M., Friesen, P. D., Poirier, G., and Dixit, V. M. (1995) J. Biol. Chem. 270, 16526-16528
13. Xue, D., and Horvitz, H. R. (1995) Nature 377, 248-251
14. Martinou, I., Fernandez, P. A., Missotten, M., White, E., Allet, B., Sadoul, R., and Martinou, J. C. (1995) J. Cell Biol. 128, 201-208
15. Robertson, N. M., Zangrilli, J., Fernandes-Alnemri, T., Friesen, P. D., Litwack, G., and Alnemri, E. S. (1997) Cancer Res. 57, 43-47
16. Izquierdo, M., Grandien, A., Criado, L. M., Rabies, S., Leonardo, E., Albar, J. P., de Buitrago, G. G., and Martinez, A. C. (1999) EMBO J. 18, 156-166
17. Davidson, F. F., and Steller, H. (1998) Nature 391, 587-591
18. Jacobson, M. D. (1998) Curr. Biol. 8, 418-421
19. Bump, N. J., Hackett, M., Hugunin, M., Seshagiri, S., Brady, K., Chen, P., Ferenz, C., Franklin, S., Ghayur, T., Li, P., Licari, P., Mankovich, J., Shi, L., Greenberg, A. H., Miller, L. K., and Wong, W. W. (1995) Science 269, 1885-1888
20. Zhou, Q., Krebs, J. F., Snipas, S. J., Price, A., Alnemri, E. S., Tomaselli, K. J., and Salvesen, G. S. (1998) Biochemistry 37, 10757-10765
21. Ahmad, M., Srinivasula, S. M., Wang, L., Litwack, G., Fernandes-Alnemri, T., and Alnemri, E. S. (1997) J. Biol. Chem. 272, 1421-1424
22. Thornberry, N. A., Ranon, T. A., Peterson, E. P., Rasper, D. M., Timkey, T., Garcia-Calvo, M., Houtzager, V. M., Nordstrom, P. A., Roy, S., Vaillancourt, J. P., Chapman, K. T., and Nicholson, D. W. (1997) J. Biol. Chem. 272, 17907-17911
23. Fisher, A., dela Cruz, W., Zoog, S. J., Schneider, C. L., and Friesen, P. D. (1999) EMBO J. 18, 2031-2039
24. Hershberger, P. A., LaCount, D. J., and Friesen, P. D. (1994) J. Virol. 68, 3467-3477
25. Kunkel, T. A., Roberts, J. D., and Zakour, R. A. (1987) Methods Enzymol. 154, 367-382
26. Vaughn, J. L., Goodwin, R. H., Thompkins, G. L., and McCawley, P. (1977) In Vitro 13, 213-217
27. Schietsl, R. H., and Gietz, R. D. (1989) Curr. Genet. 19, 339-346
28. Breeden, L., and Nasmyth, K. (1985) Cold Spring Harbor Symp. Quant. Biol. 50, 643-650
29. Guarente, L. (1983) Methods Enzymol. 101, 181-191
30. Miller, J. H. (1972) CSH Laboratory Press, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
31. Fields, S. A., and Ok-Kyu, S. (1989) Nature 340, 245-246
32. Huang, Z. J., Curtin, K. D., and Roshbash, M. (1995) Science 267, 1169-1172
33. Huang, L., Ichimaru, E., Pestonjamasp, K., Cui, X., Nakamura, H., Lo, G. Y. H., Lin, F. I. K., Luna, E. J., and Fyrthmayr, H. (1998) Biochem. Biophys. Res. Commun. 248, 548-553
34. Bartel, P. L., Roecklein, J. A., SenGupta, D., and Fields, S. (1996) Nat. Genet. 12, 72-77
35. Whisstock, J., Skinner, R., and Lesk, A. M. (1998) Trend Biochem. Sci. 23, 63-67
36. Merrit, E. A., and Murphy, M. E. P. (1994) Acta Crystallogr. Sect. D 50, 869-873
37. Mittl, P. R. E., Di Marco, S., Krebs, J. F., Bai, X., Karanewsky, D. S., Priestle, J. P., Tomaselli, K. J., and Grutter, M. G. (1997) J. Biol. Chem. 272, 6539-6547
38. Rotonda, J., Nicholson, D. W., Fazil, K. M., Gallant, M., Gareau, Y., Labelle, M., Peterson, E. P., Rasper, D. M., Ruel, R., Vaillancourt, J. P., Thornberry, N. A., and Becker, J. W. (1996) Nature Struct. Biol. 3, 619-625
39. Walker, N. P., Talanian, R. V., Brady, K. D., Dang, L. C., Bump, N. J., Ferenz, C. R., Franklin, S., Ghayur, T., Hackett, M. C., Hammill, L. D., et al. (1994) Cell 78, 343-352
40. Wilson, K. P., Black, J. A., Thomson, J. A., Kim, E. E., Griffith, J. P., Navia, M. A., Murcko, M. A., Chambers, S. P., Aldape, R. A., Raybuck, S. A., and Livingston, D. J. (1994) Nature 370, 270-275
41. Cartier, J. L., Hershberger, P. A., and Friesen, P. D. (1994) J. Virol. 68, 7728-7737
42. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950
43. Bacon, D. J., and Anderson, W. F. (1988) J. Mol. Graphics 6, 219-220