Mutational analysis of potential zinc-binding residues in the active site of the enterococcal D-Ala-D-Ala dipeptidase VanX

Biochemistry

Volumn 36, Issue 34, 1997, Pages 10498-10505

  McCafferty, Dewey G ^a   Lessard, Ivan A D ^a   Walsh, Christopher T ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; BACTERIAL ENZYME; CARBOXYPEPTIDASE; DIPEPTIDASE; GLUTAMIC ACID; HISTIDINE; HYBRID PROTEIN; MALTOSE BINDING PROTEIN; MUTANT PROTEIN; RECOMBINANT DNA; THERMOLYSIN; VANCOMYCIN; ZINC;

AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; ENTEROCOCCUS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL PROTEINS; BINDING SITES; CARRIER PROTEINS; CIRCULAR DICHROISM; CONSERVED SEQUENCE; DIPEPTIDASES; DNA MUTATIONAL ANALYSIS; ENTEROCOCCUS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; KINETICS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MONOSACCHARIDE TRANSPORT PROTEINS; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; SERINE-TYPE D-ALA-D-ALA CARBOXYPEPTIDASE; THERMOLYSIN; THROMBIN; ZINC;

BACILLUS THERMOPROTEOLYTICUS; BACTERIA (MICROORGANISMS); ENTEROCOCCUS; ERINACEIDAE; MURINAE; STREPTOMYCES; STREPTOMYCES ALBUS G;

EID: 0030779872     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970543u     Document Type: Article

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