T-cell development: A role for self-peptides in positive selection

Current Biology

Volumn 9, Issue 9, 1999, Pages

  Janeway Jr , Charles A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0033529036     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(99)80209-7     Document Type: Review

References (24)

1. von Boehmer H: Positive selection of lymphocytes. Cell 1994, 76:219-228.
2. Nossal GJ: Negative selection of lymphocytes. Cell 1994, 76:229-239.
3. Laufer TM, DeKoning J, Markowitz JS, Lo D, Glimcher LH: Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex. Nature 1996, 383:81-85.
4. van Meerwijk JP, Marguerat S, Lees RK, Germain RN, Fowlkes BJ, MacDonald HR: Quantitative impact of thymic clonal deletion on the T cell repertoire. J Exp Med 1997, 185:377-383.
5. Merkenschlager M, Graf D, Lovatt M, Bommhardt U, Zamoyska R, Fisher AG: How many thymocytes audition for selection? J Exp Med 1997, 186:1149-1158.
6. Ignatowicz L, Kappler J, Marrack P: The repertoire of T cells shaped by a single MHC/peptide ligand. Cell 1996, 84:521-529.
7. Miyazaki T, Wolf P, Tourne S, Waltzinger C, Dierich A, Barois N, Ploegh H, Benoist C, Mathis D: Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway. Cell 1996, 84:531-541.
8. Bevan MJ: In thymic selection, peptide diversity gives and takes away. Immunity 1997, 7:175-178.
9. Barton GM, Rudensky AY: Requirement for diverse, low-abundance peptides in positive selection of T cells. Science 1999, 283:67-70.
10. Baldwin KK, Reay PA, Wu L, Farr A, Davis MM: A T cell receptor-specific blockade of positive selection. J Exp Med 1999, 189:13-24.
11. + T cells induced by major histocompatibility complex binding peptides in fetal thymic organ culture. J Exp Med 1993, 177:1469-1473.
12. + T cells in the thymus. Cell 1993, 73:1041-1049.
13. Hogquist KA, Jameson SC, Heath WR, Howard JL, Bevan MJ, Carbone FR: T cell receptor antagonist peptides induce positive selection. Cell 1994, 76:17-27.
14. Ashton-Rickardt PG, Bandeira A, Delaney JR, Van Kaer L, Pircher HP, Zinkernagel RM, Tonegawa S: Evidence for a differential avidity model of T cell selection in the thymus. Cell 1994, 76:651-663.
15. Jameson SC, Hogquist KA, Bevan MJ: Specificity and flexibility in thymic selection. Nature 1994, 369:750-752.
16. Sebzda E, Wallace VA, Mayer J, Yeung RS, Mak TW, Ohashi PS: Positive and negative thymocyte selection induced by different concentrations of a single peptide. Science 1994, 263:1615-1618.
17. Hogquist KA, Tomlinson AJ, Kieper WC, McGargill MA, Hart MC, Naylor S, Jameson SC: Identification of a naturally occurring ligand for thymic positive selection. Immunity 1997, 6:389-399.
18. Hu Q, Bazemore-Walker CR, Girao C, Opferman JT, Sun J, Shabanowitz J, Hunt DF, Ashton-Rickardt PG: Specific recognition of thymic self-peptides induces the positive selection of cytotoxic T lymphocytes. Immunity 1997, 7:221-231.
19. + T cell selection in mice lacking invariant chain expression. J Exp Med 1993, 177:1699-1712.
20. Rudensky A, Preston-Hurlburt P, Hong SC, Barlow A, Janeway CA Jr: Sequence analysis of peptides bound to MHC class II molecules. Nature 1991, 353:622-627.
21. Sant'Angelo DB, Waterbury PG, Cohen BE, Martin WD, Van Kaer L, Hayday AC, Janeway CA Jr: The imprint of intrathymic self-peptides on the mature T cell receptor repertoire. Immunity 1997, 7:517-524.
22. Grubin CE, Kovats S, deRoos P, Rudensky AY: Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides. Immunity 1997, 7:197-208.
23. Rudensky A, Rath S, Preston-Hurlburt P, Murphy DB, Janeway CA Jr: On the complexity of self. Nature 1991, 353:660-662.
24. Nakagawa T, Roth W, Wong P, Nelson A, Farr A, Deussing J, Villadangos JA, Ploegh H, Peters C, Rudensky AY: Cathepsin L: Critical role in Ii degradation and CD4 T cell selection in the thymus. Science 1998, 280:450-453.