Substitution of a conserved amino acid residue alters the ligand binding properties of peroxisome proliferator activated receptors

FEBS Letters

Volumn 463, Issue 3, 1999, Pages 205-210

  Causevic, Mirsada ^a   Wolf, C Roland ^a   Palmer, Colin N A ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Diabetes; Fatty acid; Fluorescence; Nuclear receptor; Peroxisome proliferator; Thiazolidinedione

Indexed keywords

CELL NUCLEUS RECEPTOR; FATTY ACID; GLUTAMIC ACID; GLYCINE; PARINARIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; FLUORESCENCE; LIGAND BINDING; LIPID METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; ESCHERICHIA COLI; FATTY ACIDS, UNSATURATED; FLUORESCENT DYES; GENE EXPRESSION; GLUTAMIC ACID; HUMANS; LIGANDS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS;

EID: 0033437183     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)01618-X     Document Type: Article

References (30)

1. Issemann I., Green S. Nature. 347:1990;645-650.
2. Palmer C.N.A., Hsu M.H., Griffin K.J., Raucy J.L., Johnson E.F. Mol. Pharmacol. 53:1998;14-22.
3. Kersten S., Seydoux J., Peters J.M., Gonzalez F.J., Desvergne B., Wahli W. J. Clin. Invest. 103:1999;1489-1498.
4. Lee S.S., Pineau T., Drago J., Lee E.J., Owens J.W., Kroetz D.L., Fernandez S.P., Westphal H., Gonzalez F.J. Mol. Cell. Biol. 15:1995;3012-3022.
5. Peters J.M., Cattley R.C., Gonzalez F.J. Carcinogenesis. 18:1997;2029-2033.
6. Lim H., Gupta R.A., Ma W.G., Paria B.C., Moller D.E., Morrow J.D., DuBois R.N., Trzaskos J.M., Dey S.K. Genes Dev. 13:1999;1561-1574.
7. Saltiel A.R., Olefsky J.M. Diabetes. 45:1996;1661-1669.
8. Ricote M., Huang J., Fajas L., Li A., Welch J., Najib J., Witztum J.L., Auwerx J., Palinski W., Glass C.K. Proc. Natl. Acad. Sci. USA. 95:1998;7614-7619.
9. Ricote M., Li A.C., Willson T.M., Kelly C.J., Glass C.K. Nature. 391:1998;79-82.
10. Mueller E., Sarraf P., Tontonoz P., Evans R.M., Martin K.J., Zhang M., Fletcher C., Singer S., Spiegelman B.M. Mol. Cell. 1:1998;465-470.
11. Sarraf P., Mueller E., Jones D., King F.J., DeAngelo D.J., Partridge J.B., Holden S.A., Chen L.B., Singer S., Fletcher C., Spiegelman B.M. Nat. Med. 4:1998;1046-1052.
12. Sarraf P., Mueller E., Smith W.M., Wright H.M., Kum J.B., Aaltonen L.A., de la Chapelle A., Spiegelman B.M., Eng C. Mol. Cell. 3:1999;799-804.
13. Tontonoz P., Graves R.A., Budavari A.I., Erdjument B.H., Lui M., Hu E., Tempst P., Spiegelman B.M. Nucleic Acids Res. 22:1994;5628-5634.
14. Tontonoz P., Hu E., Spiegelman B.M. Cell. 79:1994;1147-1156.
15. Tontonoz P., Hu E., Graves R.A., Budavari A.I., Spiegelman B.M. Genes Dev. 8:1994;1224-1234.
16. Forman B.M., Tontonoz P., Chen J., Brun R.P., Spiegelman B.M., Evans R.M. Cell. 83:1995;803-812.
17. Kliewer S.A., Lenhard J.M., Willson T.M., Patel I., Morris D.C., Lehmann J.M. Cell. 83:1995;813-819.
18. Lehmann J.M., Moore L.B., Smith O.T., Wilkison W.O., Willson T.M., Kliewer S.A. J. Biol. Chem. 270:1995;12953-12956.
19. Jiang C., Ting A.T., Seed B. Nature. 391:1998;82-86.
20. Hsu M.H., Palmer C.N.A., Griffin K.J., Johnson E.F. Mol. Pharmacol. 48:1995;559-567.
21. Palmer C.N., Hsu M.H., Muerhoff A.S., Griffin K.J., Johnson E.F. J. Biol. Chem. 269:1994;18083-18089.
22. Forman B.M., Chen J., Evans R.M. Proc. Natl. Acad. Sci. USA. 94:1997;4312-4317.
23. Palmer C.N.A., Wolf C.R. FEBS Lett. 431:1998;476-480.
24. Young P.W., Buckle D.R., Cantello B., Chapman H., Clapham J.C., Coyle P.J., Haigh D., Hindley R.M., Holder J.C., Kallender H., Latter A.J., Lawrie K., Mossakowska D., Murphy G.J., Cox L.R., Smith S.A. J. Pharmacol. Exp. Ther. 284:1998;751-759.
25. English N., Palmer C.N.A., Alworth W.L., Kang L., Hughes V., Wolf C.R. Biochem. J. 316:1997;279-283.
26. Palmer C.N.A., Axen E., Hughes V., Wolf C.R. J. Biol. Chem. 273:1998;18109-18116.
27. Sha R.S., Kane C.D., Xu Z., Banaszak L.J., Bernlohr D.A. J. Biol. Chem. 268:1993;7885-7892.
28. Brzozowski A.M., Pike A.C., Dauter Z., Hubbard R.E., Bonn T., Engstrom O., Ohman L., Greene G.L., Gustafsson J.A., Carlquist M. Nature. 389:1997;753-758.
29. Xu H.E., Lambert M.H., Montana V.G., Parks D.J., Blanchard S.G., Brown P.J., Sternbach D.D., Lehmann J.M., Wisely G.B., Willson T.M., Kliewer S.A., Milburn M.V. Mol. Cell. 3:1999;397-403.
30. Nolte R.T., Wisely G.B., Westin S., Cobb J.E., Lambert M.H., Kurokawa R., Rosenfeld M.G., Willson T.M., Glass C.K., Milburn M.V. Nature. 395:1998;137-143.