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Volumn 8, Issue 5, 1999, Pages 549-556

Endothelin antagonists for hypertension and renal disease

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIN; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST;

EID: 0033404490     PISSN: 10624821     EISSN: None     Source Type: Journal    
DOI: 10.1097/00041552-199909000-00003     Document Type: Review
Times cited : (32)

References (89)
  • 1
    • 0022067275 scopus 로고
    • Characterization of a coronary vasoconstrictor produced by cultured endothelial cells
    • 1 Hickey KA, Rubanyi GM, Paul RJ, Highsmith RF. Characterization of a coronary vasoconstrictor produced by cultured endothelial cells. Am J Physiol 1985; 248:C550-C556.
    • (1985) Am J Physiol , vol.248
    • Hickey, K.A.1    Rubanyi, G.M.2    Paul, R.J.3    Highsmith, R.F.4
  • 2
    • 0023859136 scopus 로고
    • A novel potent vasoconstrictor peptide produced by vascular endothelial cells
    • 2 Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988; 332:411-415.
    • (1988) Nature , vol.332 , pp. 411-415
    • Yanagisawa, M.1    Kurihara, H.2    Kimura, S.3    Tomobe, Y.4    Kobayashi, M.5    Mitsui, Y.6
  • 3
    • 0028307066 scopus 로고
    • Constitutive endothelin-1 overexpression promotes smooth muscle cell proliferation via an external autocrine loop
    • 3 Alberts GF, Peifley KA, Johns A, Kleha JF, Winkles JA. Constitutive endothelin-1 overexpression promotes smooth muscle cell proliferation via an external autocrine loop. J Biol Chem 1994; 269:10112-10118.
    • (1994) J Biol Chem , vol.269 , pp. 10112-10118
    • Alberts, G.F.1    Peifley, K.A.2    Johns, A.3    Kleha, J.F.4    Winkles, J.A.5
  • 4
    • 0029120520 scopus 로고
    • Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin-1 gene expression
    • 4 Fujisaki H, Ito H, Hirata Y, Tanaka M, Hata M, Lin M, et al. Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin-1 gene expression. J Clin Invest 1995; 96:1059-1065.
    • (1995) J Clin Invest , vol.96 , pp. 1059-1065
    • Fujisaki, H.1    Ito, H.2    Hirata, Y.3    Tanaka, M.4    Hata, M.5    Lin, M.6
  • 5
    • 0031590298 scopus 로고    scopus 로고
    • Angiotensin II increases vascular and renal endothelin-1 and functional endothelin converting enzyme activity in vivo: Role of ETA-receptors for endothelin regulation
    • 5 Barton M, Shaw S, d'Uscio LV, Moreau P, Lüscher TF. Angiotensin II increases vascular and renal endothelin-1 and functional endothelin converting enzyme activity in vivo: role of ETA-receptors for endothelin regulation. Biochem Biophys Res Commun 1997; 238:861-865.
    • (1997) Biochem Biophys Res Commun , vol.238 , pp. 861-865
    • Barton, M.1    Shaw, S.2    D'Uscio, L.V.3    Moreau, P.4    Lüscher, T.F.5
  • 6
    • 0027257160 scopus 로고
    • Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes
    • 6 Ito H, Hirata Y, Adachi S, Tanaka M, Tsujino M, Koike A, et al. Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes. J Clin Invest 1993; 92:398-403.
    • (1993) J Clin Invest , vol.92 , pp. 398-403
    • Ito, H.1    Hirata, Y.2    Adachi, S.3    Tanaka, M.4    Tsujino, M.5    Koike, A.6
  • 7
    • 0028929832 scopus 로고
    • Endothelin receptor subtype B mediates autoinduction of endothelin-1 in rat mesangial cells
    • 7 Iwasaki S, Homma T, Matsuda Y, Kon V. Endothelin receptor subtype B mediates autoinduction of endothelin-1 in rat mesangial cells. J Biol Chem 1995; 270:6997-7003.
    • (1995) J Biol Chem , vol.270 , pp. 6997-7003
    • Iwasaki, S.1    Homma, T.2    Matsuda, Y.3    Kon, V.4
  • 8
    • 0033068028 scopus 로고    scopus 로고
    • Pathophysiology of endothelin in the cardiovascular system
    • 8 Miyauchi T, Masaki T. Pathophysiology of endothelin in the cardiovascular system. Annu Rev Physiol 1999; 61:391-415. Excellent up-to-date review of the molecular actions and pathophysiologic significance of endothelin in cardiovascular disease.
    • (1999) Annu Rev Physiol , vol.61 , pp. 391-415
    • Miyauchi, T.1    Masaki, T.2
  • 9
    • 0013543367 scopus 로고
    • The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three separate genes
    • 9 Inoue A, Yanagisawa M, Kimura S, Kasuya Y, Miyauchi T, Goto K, Masaki T. The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci U S A 1989; 86:2863-2867.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 2863-2867
    • Inoue, A.1    Yanagisawa, M.2    Kimura, S.3    Kasuya, Y.4    Miyauchi, T.5    Goto, K.6    Masaki, T.7
  • 10
    • 0024433980 scopus 로고
    • A novel peptide, vasoactive intestinal contractor, of a new (endothelin) peptide family. Molecular cloning, expression and biological activity
    • 10 Saida K, Mitsui Y, Ishida N. A novel peptide, vasoactive intestinal contractor, of a new (endothelin) peptide family. Molecular cloning, expression and biological activity. J Biol Chem 1989; 264:14613-14616.
    • (1989) J Biol Chem , vol.264 , pp. 14613-14616
    • Saida, K.1    Mitsui, Y.2    Ishida, N.3
  • 11
    • 0025847317 scopus 로고
    • cDNA cloning and chromosomal assignment of the endothelin-2 gene: Vasoactive intestinal contractor peptide is rat endothelin-2
    • 11 Bloch KD, Hong CC, Eddy RL, Shows TB, Quertermous T. cDNA cloning and chromosomal assignment of the endothelin-2 gene: vasoactive intestinal contractor peptide is rat endothelin-2. Genomics 1991; 10:236-242.
    • (1991) Genomics , vol.10 , pp. 236-242
    • Bloch, K.D.1    Hong, C.C.2    Eddy, R.L.3    Shows, T.B.4    Quertermous, T.5
  • 13
    • 0026699032 scopus 로고
    • Physiological fluid shear stress causes downregulation of endothelin-1 mRNA in bovine aortic endothelium
    • 13 Malek A, Izumo S. Physiological fluid shear stress causes downregulation of endothelin-1 mRNA in bovine aortic endothelium. Am J Physiol 1992; 263:C389-396.
    • (1992) Am J Physiol , vol.263
    • Malek, A.1    Izumo, S.2
  • 14
    • 0032005875 scopus 로고    scopus 로고
    • Reduced extracellular pH increases endothelin-1 secretion by human renal microvascular endothelial cells
    • Interesting report demonstrating a role of pH as a regulator of endothelin release with important clinical implications on acid-base disturbances
    • 14 Wesson De, Simoni J, Green DF. Reduced extracellular pH increases endothelin-1 secretion by human renal microvascular endothelial cells. J Clin Invest 1998; 101:578-583. Interesting report demonstrating a role of pH as a regulator of endothelin release with important clinical implications on acid-base disturbances.
    • (1998) J Clin Invest , vol.101 , pp. 578-583
    • Wesson, De.1    Simoni, J.2    Green, D.F.3
  • 15
    • 0031878495 scopus 로고    scopus 로고
    • Stimulatory interaction between vascular endothelial growth factor and endothelin-1 on each gene expression
    • 15 Matsuura A, Yamochi W, Hirata K, Kawashima S, Yokoyama M. Stimulatory interaction between vascular endothelial growth factor and endothelin-1 on each gene expression. Hypertension 1998; 32:89-95.
    • (1998) Hypertension , vol.32 , pp. 89-95
    • Matsuura, A.1    Yamochi, W.2    Hirata, K.3    Kawashima, S.4    Yokoyama, M.5
  • 17
    • 0029747169 scopus 로고    scopus 로고
    • Endothelin-1 modulates the expression of adhesion molecules on fibroblast-like synovial cells (FLS)
    • 17 Schwarting A, Schlaak J, Lotz J, Pfers I, Meyer BK, Mayer W. Endothelin-1 modulates the expression of adhesion molecules on fibroblast-like synovial cells (FLS). Scand J Rheumatol 1996; 25:246-256.
    • (1996) Scand J Rheumatol , vol.25 , pp. 246-256
    • Schwarting, A.1    Schlaak, J.2    Lotz, J.3    Pfers, I.4    Meyer, B.K.5    Mayer, W.6
  • 18
    • 0025100874 scopus 로고
    • Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide
    • 18 Boulanger C, Lüscher TF. Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide. J Clin Invest 1990; 85:587-590.
    • (1990) J Clin Invest , vol.85 , pp. 587-590
    • Boulanger, C.1    Lüscher, T.F.2
  • 19
    • 0028121671 scopus 로고
    • Role of cyclic nucleotides in the regulation of endothelin-1 production by human endothelial cells
    • 19 Stewart D, Cernacek P, Mohamed F, Blais D, Cianflone K, Monge JC. Role of cyclic nucleotides in the regulation of endothelin-1 production by human endothelial cells. Am J Physiol 1994; 266:H944-H951.
    • (1994) Am J Physiol , vol.266
    • Stewart, D.1    Cernacek, P.2    Mohamed, F.3    Blais, D.4    Cianflone, K.5    Monge, J.C.6
  • 20
    • 0029889793 scopus 로고    scopus 로고
    • Endogenous atrial natriuretic peptide inhibits endothelin-1 secretion in dogs with severe congestive heart failure
    • 20 Wada A, Tsutamato T, Maeda Y, Kanamori T, Matsuda Y, Kinoshita M. Endogenous atrial natriuretic peptide inhibits endothelin-1 secretion in dogs with severe congestive heart failure. Am J Physiol 1996.
    • (1996) Am J Physiol
    • Wada, A.1    Tsutamato, T.2    Maeda, Y.3    Kanamori, T.4    Matsuda, Y.5    Kinoshita, M.6
  • 21
    • 0032521501 scopus 로고    scopus 로고
    • Oestrogen and progesterone inhibit the stimulated production of endothelin-1
    • 21 Morey AK, Razandi M, Pedram A, Hu RM, Prins BA, Levin ER. Oestrogen and progesterone inhibit the stimulated production of endothelin-1. Biochem J 1998; 330:1097-1105.
    • (1998) Biochem J , vol.330 , pp. 1097-1105
    • Morey, A.K.1    Razandi, M.2    Pedram, A.3    Hu, R.M.4    Prins, B.A.5    Levin, E.R.6
  • 22
    • 0026534801 scopus 로고
    • Role of mast cell chymase in the extracellular processing of big-endothelin-1 to endothelin-1 in the perfused rat lung
    • 22 Wypij DM, Nichols JS, Novak PJ, Stacy L, Berman J, Wiseman JS. Role of mast cell chymase in the extracellular processing of big-endothelin-1 to endothelin-1 in the perfused rat lung. Biochem Pharmacol 1992; 43:845-853.
    • (1992) Biochem Pharmacol , vol.43 , pp. 845-853
    • Wypij, D.M.1    Nichols, J.S.2    Novak, P.J.3    Stacy, L.4    Berman, J.5    Wiseman, J.S.6
  • 23
    • 0009059902 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel metalloprotease that cleaves big-endothelin-1 to produce active endothelin-1
    • 23 Ikeda K, Emoto N, Matsuura A, Raharjo SB, Nurhantara Y, Alimsordjono H, Matsuo M. Molecular cloning and characterization of a novel metalloprotease that cleaves big-endothelin-1 to produce active endothelin-1 (abstract). Circulation 1998; 98:1-745.
    • (1998) Circulation , vol.98 , pp. 1-745
    • Ikeda, K.1    Emoto, N.2    Matsuura, A.3    Raharjo, S.B.4    Nurhantara, Y.5    Alimsordjono, H.6    Matsuo, M.7
  • 24
    • 0030700341 scopus 로고    scopus 로고
    • Novel activity of endothelin-converting enzyme: Hydrolysis of bradykinin
    • This study and the study of Johnson et al. [25] first demonstrated that endothelin converting enzyme is not selective for the conversion of big endothelin-1 but also inactivates bradykinin, substance P, and insulin
    • 24 Hoang MV, Turner AJ. Novel activity of endothelin-converting enzyme: hydrolysis of bradykinin. Biochem J 1998; 327:23-26. This study and the study of Johnson et al. [25] first demonstrated that endothelin converting enzyme is not selective for the conversion of big endothelin-1 but also inactivates bradykinin, substance P, and insulin.
    • (1998) Biochem J , vol.327 , pp. 23-26
    • Hoang, M.V.1    Turner, A.J.2
  • 25
    • 0033548194 scopus 로고    scopus 로고
    • Hydrolysis of peptide hormones by endothelin-converting enzyme-1. A comparison with neprilysin
    • 25 Johnson GD, Stevenson T, Ahn K. Hydrolysis of peptide hormones by endothelin-converting enzyme-1. A comparison with neprilysin. J Biol Chem 1999; 274:4053-4058.
    • (1999) J Biol Chem , vol.274 , pp. 4053-4058
    • Johnson, G.D.1    Stevenson, T.2    Ahn, K.3
  • 27
    • 0032212244 scopus 로고    scopus 로고
    • Endothelin-1 induces production of the neutrophil chemotactic factor interleukin-8 by human brain-derived endothelial cells
    • 27 Hofman FM, Chen P, Jeyaseelan R, Incardona F, Fisher M, Zidovetzki R. Endothelin-1 induces production of the neutrophil chemotactic factor interleukin-8 by human brain-derived endothelial cells. Blood 1998; 92:3064-3072.
    • (1998) Blood , vol.92 , pp. 3064-3072
    • Hofman, F.M.1    Chen, P.2    Jeyaseelan, R.3    Incardona, F.4    Fisher, M.5    Zidovetzki, R.6
  • 28
    • 0032488543 scopus 로고    scopus 로고
    • Angiotensin II and endothelin-1 increase fibroblast growth factor-2 mRNA expression in vascular smooth muscle cells
    • 28 Peifley KA, Winkles JA. Angiotensin II and endothelin-1 increase fibroblast growth factor-2 mRNA expression in vascular smooth muscle cells. Biochem Biophys Res Commun 1998; 242:202-208.
    • (1998) Biochem Biophys Res Commun , vol.242 , pp. 202-208
    • Peifley, K.A.1    Winkles, J.A.2
  • 29
    • 0008970149 scopus 로고    scopus 로고
    • Endothelin-1 stimulates collagen synthesis in cultured human cardiac fibroblasts via the ETA receptor
    • 29 Hafizi S, Wharton J, Chester AH, Polak JM, Jacoub MH. Endothelin-1 stimulates collagen synthesis in cultured human cardiac fibroblasts via the ETA receptor (abstract). Circulation 1998; 98:1-79.
    • (1998) Circulation , vol.98 , pp. 1-79
    • Hafizi, S.1    Wharton, J.2    Chester, A.H.3    Polak, J.M.4    Jacoub, M.H.5
  • 30
    • 0029941111 scopus 로고    scopus 로고
    • Endothelin-1 induces increased fibronectin expression in human bronchial epithelial cells
    • 30 Marini M, Carpi S, Bellini A, Patalano F, Mattoli S. Endothelin-1 induces increased fibronectin expression in human bronchial epithelial cells. Biochem Biophys Res Commun 1996; 220:896-899.
    • (1996) Biochem Biophys Res Commun , vol.220 , pp. 896-899
    • Marini, M.1    Carpi, S.2    Bellini, A.3    Patalano, F.4    Mattoli, S.5
  • 31
    • 0025668415 scopus 로고
    • The endothelin peptides ET-1, ET-2, ET-3 and sarafatoxin S6c are comitogenic with platelet derived growth factor for vascular smooth muscte cells
    • 31 Weissberg PL, Witchel C, Davenport AP, Herketh TR, Metcalfe JC. The endothelin peptides ET-1, ET-2, ET-3 and sarafatoxin S6c are comitogenic with platelet derived growth factor for vascular smooth muscte cells. Atherosclerosis 1990; 83:257-262.
    • (1990) Atherosclerosis , vol.83 , pp. 257-262
    • Weissberg, P.L.1    Witchel, C.2    Davenport, A.P.3    Herketh, T.R.4    Metcalfe, J.C.5
  • 32
    • 0032577069 scopus 로고    scopus 로고
    • Astrocyte progression from G1 to S phase of the cell cycle depends upon multiple protein interaction
    • 32 Pedram A, Razandi M, Hu RM, Levin ER. Astrocyte progression from G1 to S phase of the cell cycle depends upon multiple protein interaction. J Biol Chem 1998; 273:13966-13972.
    • (1998) J Biol Chem , vol.273 , pp. 13966-13972
    • Pedram, A.1    Razandi, M.2    Hu, R.M.3    Levin, E.R.4
  • 33
    • 0033582962 scopus 로고    scopus 로고
    • Molecular mechanisms of endothelin-1-induced cell-cycle progression. Involvement of extracellular signal-regulated kinase, protein kinase C, and phosphatidylinositol e-kinase at distinct points
    • This study demonstrated the involvement of kinases as downstream mediators of endothelin-1-induced progression of the cell cycle
    • 33 Suzuki E, Nagata D, Kakoki M, Hayakawa H, Goto A, Omata M, Hirata Y. Molecular mechanisms of endothelin-1-induced cell-cycle progression. Involvement of extracellular signal-regulated kinase, protein kinase C, and phosphatidylinositol e-kinase at distinct points. Circ Res 1999; 84:611-619. This study demonstrated the involvement of kinases as downstream mediators of endothelin-1-induced progression of the cell cycle.
    • (1999) Circ Res , vol.84 , pp. 611-619
    • Suzuki, E.1    Nagata, D.2    Kakoki, M.3    Hayakawa, H.4    Goto, A.5    Omata, M.6    Hirata, Y.7
  • 34
    • 0028987867 scopus 로고
    • Possible role of endothelin in endothelial regulation of vascular tone
    • 34 Masaki T. Possible role of endothelin in endothelial regulation of vascular tone. Annu Rev Pharmacol Toxicol 1995;235-255.
    • (1995) Annu Rev Pharmacol Toxicol , pp. 235-255
    • Masaki, T.1
  • 35
    • 2642701219 scopus 로고
    • Endothelin activates the dihydropyridine-sensitive voltage-dependent Ca(2+) channel in vascular smooth muscle
    • 35 Goto K, Kasuya Y, Matsuki N, Takuwa Y, Kurihara H, Ishikawa T, et al. Endothelin activates the dihydropyridine-sensitive voltage-dependent Ca(2+) channel in vascular smooth muscle. Proc Natl Acad Sci U S A 1989; 86:3915-3918.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 3915-3918
    • Goto, K.1    Kasuya, Y.2    Matsuki, N.3    Takuwa, Y.4    Kurihara, H.5    Ishikawa, T.6
  • 36
    • 0024581086 scopus 로고
    • Endothelin-1 and endothelin-3 release EDRF from isolated perfused arterial vessels of the rat and rabbit
    • 36 Warner TD, Mitchell JA, de Nucci G, Vane JR. Endothelin-1 and endothelin-3 release EDRF from isolated perfused arterial vessels of the rat and rabbit. J Cardiovasc Pharmacol 1989; 13:S85-S88.
    • (1989) J Cardiovasc Pharmacol , vol.13
    • Warner, T.D.1    Mitchell, J.A.2    De Nucci, G.3    Vane, J.R.4
  • 37
    • 0027299798 scopus 로고
    • Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells
    • 37 Hirata Y, Emori T, Eguichi S, Kanno K, Imai T, Ohta K, Marumo F. Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells. J Clin Invest 1993; 91:1367-1372.
    • (1993) J Clin Invest , vol.91 , pp. 1367-1372
    • Hirata, Y.1    Emori, T.2    Eguichi, S.3    Kanno, K.4    Imai, T.5    Ohta, K.6    Marumo, F.7
  • 38
    • 0031739910 scopus 로고    scopus 로고
    • Autocrine role for the endothelin-B receptor in the secretion of adrenomedullin
    • B-receptor mediated autocrine regulation of the endothelium-derived vasodilator adrenomedullin
    • B-receptor mediated autocrine regulation of the endothelium-derived vasodilator adrenomedullin.
    • (1998) Hypertension , vol.32 , pp. 917-922
    • Jougasaki, M.1    Schirger, J.A.2    Simari, R.D.3    Burnett J.C., Jr.4
  • 39
    • 0030667291 scopus 로고    scopus 로고
    • Endothelin-1 as an autocrine/paracrine spoptosis survival factor for endothelial cells
    • 39 Shichiri M, Kato M, Marumo F, Hirata Y. Endothelin-1 as an autocrine/paracrine spoptosis survival factor for endothelial cells. Hypertension 1997; 30:1198-1203.
    • (1997) Hypertension , vol.30 , pp. 1198-1203
    • Shichiri, M.1    Kato, M.2    Marumo, F.3    Hirata, Y.4
  • 40
    • 0032570314 scopus 로고    scopus 로고
    • Endothelin-1 inhibits endothelin-converting enzyme-1 expression in cultured rat pulmonary endothelial cells
    • 40 Naomi S, Iwaoka T, Disashi T, Inoue J, Kanesaka Y, Tokunaga H, Tomita K. Endothelin-1 inhibits endothelin-converting enzyme-1 expression in cultured rat pulmonary endothelial cells. Circulation 1998; 97:234-236.
    • (1998) Circulation , vol.97 , pp. 234-236
    • Naomi, S.1    Iwaoka, T.2    Disashi, T.3    Inoue, J.4    Kanesaka, Y.5    Tokunaga, H.6    Tomita, K.7
  • 42
    • 0032986924 scopus 로고    scopus 로고
    • Endothelium-independent vascular relaxation mediating ETB receptor in rabbit mesenteric arteries
    • First study providing evidence for an endothelium-independent component of ETB-mediated vasodilatation involving prostanoids
    • 42 Iwasaki T, Notoya M, Hayasaki-Kajiwara Y, Shimaramura T, Naya N, Ninomiya M, Nakajima M. Endothelium-independent vascular relaxation mediating ETB receptor in rabbit mesenteric arteries. Am J Physiol 1999; 276:H383-H390. First study providing evidence for an endothelium-independent component of ETB-mediated vasodilatation involving prostanoids.
    • (1999) Am J Physiol , vol.276
    • Iwasaki, T.1    Notoya, M.2    Hayasaki-Kajiwara, Y.3    Shimaramura, T.4    Naya, N.5    Ninomiya, M.6    Nakajima, M.7
  • 44
    • 0032951516 scopus 로고    scopus 로고
    • Elevation of blood pressure by genetic and pharmacological disruption of the ETB receptor in mice
    • 44 Ohuchi T, Kuwaki T, Ling GY, Dewit D, KH J, Onedora M, et al. Elevation of blood pressure by genetic and pharmacological disruption of the ETB receptor in mice. Am J Physiol 1999; 276:R1071-R1077.
    • (1999) Am J Physiol , vol.276
    • Ohuchi, T.1    Kuwaki, T.2    Ling, G.Y.3    Dewit, D.4    KH, J.5    Onedora, M.6
  • 46
    • 0030317635 scopus 로고    scopus 로고
    • The role of endothelin in coronary atherosclerosis
    • 46 Mathew V, Hasdai D, Lerman A. The role of endothelin in coronary atherosclerosis. Mayo Clin Proc 1996; 71:769-777.
    • (1996) Mayo Clin Proc , vol.71 , pp. 769-777
    • Mathew, V.1    Hasdai, D.2    Lerman, A.3
  • 48
    • 0031613530 scopus 로고    scopus 로고
    • ETA receptor blockade prevents increased tissue endothelin-1, vascular hypertrophy and endothelial dysfunction in salt-sensitive hypertension
    • 48 Barton M, d'Uscio L, Shaw S, Meyer P, Moreau P, Lüscher TF. ETA receptor blockade prevents increased tissue endothelin-1, vascular hypertrophy and endothelial dysfunction in salt-sensitive hypertension. Hypertension 1998;499-504.
    • (1998) Hypertension , pp. 499-504
    • Barton, M.1    D'Uscio, L.2    Shaw, S.3    Meyer, P.4    Moreau, P.5    Lüscher, T.F.6
  • 49
    • 0033528717 scopus 로고    scopus 로고
    • Chronic endothelin receptor antagonism preserves coronary endothelial function in experimental hypercholesterolemia
    • 49 Best BJ, McKenna CJ, Hasdai D, Holmes DR Jr, Lerman A. Chronic endothelin receptor antagonism preserves coronary endothelial function in experimental hypercholesterolemia. Circulation 1999; 99:1747-1752.
    • (1999) Circulation , vol.99 , pp. 1747-1752
    • Best, B.J.1    McKenna, C.J.2    Hasdai, D.3    Holmes D.R., Jr.4    Lerman, A.5
  • 50
    • 0032564279 scopus 로고    scopus 로고
    • Endothelin ETA receptor blockade restores NO-mediated endothelial function and inhibits atherosclerosis in apoE-deficient mice
    • 50 Barton M, Haudenschild CC, d'Uscio LV, Shaw S, Münter K, Lüscher TF. Endothelin ETA receptor blockade restores NO-mediated endothelial function and inhibits atherosclerosis in apoE-deficient mice. Proc Natl Acad Sci U S A 1998; 95:14367-14372.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 14367-14372
    • Barton, M.1    Haudenschild, C.C.2    D'Uscio, L.V.3    Shaw, S.4    Münter, K.5    Lüscher, T.F.6
  • 51
    • 0032474287 scopus 로고    scopus 로고
    • EndothelinA receptor blockade improves nitric oxide-mediated vasodilation in monocrotaline-induced pulmonary hypertension
    • 51 Prie S, Stewart DJ, Dupuis J. EndothelinA receptor blockade improves nitric oxide-mediated vasodilation in monocrotaline-induced pulmonary hypertension. Circulation 1998; 97:169-174.
    • (1998) Circulation , vol.97 , pp. 169-174
    • Prie, S.1    Stewart, D.J.2    Dupuis, J.3
  • 53
    • 0027200293 scopus 로고
    • Effect of increased availability of endothelium-derived nitric oxide precursor on endothelium-dependent vascular relaxation in normal subjects and in patients with essential hypertension
    • 53 Panza JA, Casino PR, Badar DM, Quyyumi AA. Effect of increased availability of endothelium-derived nitric oxide precursor on endothelium-dependent vascular relaxation in normal subjects and in patients with essential hypertension. Circulation 1993; 87:1475-1481.
    • (1993) Circulation , vol.87 , pp. 1475-1481
    • Panza, J.A.1    Casino, P.R.2    Badar, D.M.3    Quyyumi, A.A.4
  • 54
    • 0002868866 scopus 로고    scopus 로고
    • Blood pressure independent effects of chronic selective ETA-receptor blockade in L-NAME-induced hypertension
    • 54 d'Uscio LV, Shaw S, Moreau P, Barton M, Lüscher TF. Blood pressure independent effects of chronic selective ETA-receptor blockade in L-NAME-induced hypertension. J Hypertens 1998; 16 (suppl. 2):S90.
    • (1998) J Hypertens , vol.16 , Issue.SUPPL. 2
    • D'Uscio, L.V.1    Shaw, S.2    Moreau, P.3    Barton, M.4    Lüscher, T.F.5
  • 55
    • 0031037765 scopus 로고    scopus 로고
    • Blood pressure and vascular effects of endothelin blockade in chronic nitric-oxide deficient hypertension
    • 55 Moreau P, Takase H, Kung CF, Shaw S, Lüscher TF. Blood pressure and vascular effects of endothelin blockade in chronic nitric-oxide deficient hypertension. Hypertension 1997; 29:763-769.
    • (1997) Hypertension , vol.29 , pp. 763-769
    • Moreau, P.1    Takase, H.2    Kung, C.F.3    Shaw, S.4    Lüscher, T.F.5
  • 56
    • 0032478272 scopus 로고    scopus 로고
    • Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade
    • 56 Verhaar MC, Strachan FE, Newby DE, Cruden NL, Koomans HA, Rabelink TJ, Webb DJ. Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade. Circulation 1998; 97:752-756.
    • (1998) Circulation , vol.97 , pp. 752-756
    • Verhaar, M.C.1    Strachan, F.E.2    Newby, D.E.3    Cruden, N.L.4    Koomans, H.A.5    Rabelink, T.J.6    Webb, D.J.7
  • 57
    • 0027161483 scopus 로고
    • Potential role of endothelin in hypertension. Controversy on endothelin in hypertension
    • 57 Lüscher TF, Seo BG, Bühler FR. Potential role of endothelin in hypertension. Controversy on endothelin in hypertension. Hypertension 1993; 21:752-757.
    • (1993) Hypertension , vol.21 , pp. 752-757
    • Lüscher, T.F.1    Seo, B.G.2    Bühler, F.R.3
  • 58
    • 0027959070 scopus 로고
    • Effect of a nonselective endothelin antagonist on vascular remodeling in deoxycorticosterone acetate-salt hypertensive rats. Evidence for a role of endothelin in vascular hypertrophy
    • 58 Li JS, Lariviere R, Schiffrin EL. Effect of a nonselective endothelin antagonist on vascular remodeling in deoxycorticosterone acetate-salt hypertensive rats. Evidence for a role of endothelin in vascular hypertrophy. Hypertension 1994; 24:183-185.
    • (1994) Hypertension , vol.24 , pp. 183-185
    • Li, J.S.1    Lariviere, R.2    Schiffrin, E.L.3
  • 59
    • 0030776737 scopus 로고    scopus 로고
    • Angiotensin II increases tissue endothelin and induces vascular hypertrophy: Reversal by ETA-antagonist
    • 59 Moreau P, d'Uscio LV, Takase H, Shaw S, Barton M, Lüscher TF. Angiotensin II increases tissue endothelin and induces vascular hypertrophy: reversal by ETA-antagonist. Circulation 1997; 96:1593-1597.
    • (1997) Circulation , vol.96 , pp. 1593-1597
    • Moreau, P.1    D'Uscio, L.V.2    Takase, H.3    Shaw, S.4    Barton, M.5    Lüscher, T.F.6
  • 60
    • 0028944170 scopus 로고
    • Effect of chronic treatment of adult spontaneously hypertensive rats with an endothelin antagonist
    • 60 Li JS, Schiffrin EL. Effect of chronic treatment of adult spontaneously hypertensive rats with an endothelin antagonist. Hypertension 1995; 25:495-500.
    • (1995) Hypertension , vol.25 , pp. 495-500
    • Li, J.S.1    Schiffrin, E.L.2
  • 61
    • 33745399219 scopus 로고    scopus 로고
    • Effect of endothelin antagonism on blood pressure and vascular structure in renovascular hypertensive rats
    • 61 Li JS, Knafo L, Turgeon A, Garcia R, Schiffrin EL. Effect of endothelin antagonism on blood pressure and vascular structure in renovascular hypertensive rats. Am J Physiol 1996; 271:H88-H93.
    • (1996) Am J Physiol , vol.271
    • Li, J.S.1    Knafo, L.2    Turgeon, A.3    Garcia, R.4    Schiffrin, E.L.5
  • 62
    • 0009012571 scopus 로고    scopus 로고
    • Endothelin in hypertension: A role for receptor antagonists?
    • 62 Moreau P. Endothelin in hypertension: a role for receptor antagonists? Cardiovasc Pharmacol 1998; 38:534-542.
    • (1998) Cardiovasc Pharmacol , vol.38 , pp. 534-542
    • Moreau, P.1
  • 63
    • 0028841694 scopus 로고
    • Enhanced expression of endothelin-1 gene may cause blood pressure-independent vascular hypertrophy
    • 63 Schiffrin EL, Lariviere R, Li JS, Sventek P, Touyz RM. Enhanced expression of endothelin-1 gene may cause blood pressure-independent vascular hypertrophy. J Cardiovasc Pharmacol 1995; 26:S5-S8.
    • (1995) J Cardiovasc Pharmacol , vol.26
    • Schiffrin, E.L.1    Lariviere, R.2    Li, J.S.3    Sventek, P.4    Touyz, R.M.5
  • 64
    • 1842411863 scopus 로고    scopus 로고
    • Endothelin-1 transgenic mice develop glomerulosclerosis, interstitial fibrosis, and renal cysts but not hypertension
    • 64 Hocher B, Thöne-Reinecke C, Rohmeiss P, Schmager F, Slowinski R, Burst V, et al. Endothelin-1 transgenic mice develop glomerulosclerosis, interstitial fibrosis, and renal cysts but not hypertension. J Clin Invest 1997; 99:1380-1390.
    • (1997) J Clin Invest , vol.99 , pp. 1380-1390
    • Hocher, B.1    Thöne-Reinecke, C.2    Rohmeiss, P.3    Schmager, F.4    Slowinski, R.5    Burst, V.6
  • 66
    • 0032546259 scopus 로고    scopus 로고
    • The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension
    • First clinical trial of endothelin antagonism in hypertension showing similar blood pressure lowering effects as the ACE inhibitor enalapril. Further clinical testing of the drug has been stopped due to marked hepatic side effects of bosentan
    • 66 Krum H, Viskoper RJ, Lacourciere Y, Budde M, Charlton V. The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. N Engl J Med 1998; 338:784-790. First clinical trial of endothelin antagonism in hypertension showing similar blood pressure lowering effects as the ACE inhibitor enalapril. Further clinical testing of the drug has been stopped due to marked hepatic side effects of bosentan.
    • (1998) N Engl J Med , vol.338 , pp. 784-790
    • Krum, H.1    Viskoper, R.J.2    Lacourciere, Y.3    Budde, M.4    Charlton, V.5
  • 67
    • 0009054765 scopus 로고    scopus 로고
    • Endothelin-1 markedly potentiates the proliferative effect of platelet-derived growth factor
    • 67 Yang Z, Naziri G, Lüscher TF. Endothelin-1 markedly potentiates the proliferative effect of platelet-derived growth factor. Circulation 1999; 100: 5-8.
    • (1999) Circulation , vol.100 , pp. 5-8
    • Yang, Z.1    Naziri, G.2    Lüscher, T.F.3
  • 68
    • 0024318340 scopus 로고
    • Endothelin is a potent mitogen for rat vascular smooth muscle cells
    • 68 Hirata Y, Takagi Y, Fukuda Y, Marumo F. Endothelin is a potent mitogen for rat vascular smooth muscle cells. Atherosclerosis 1989; 78:225-228.
    • (1989) Atherosclerosis , vol.78 , pp. 225-228
    • Hirata, Y.1    Takagi, Y.2    Fukuda, Y.3    Marumo, F.4
  • 69
    • 0031720741 scopus 로고    scopus 로고
    • Angiotensin II receptor blockade and end-organ protection: Pharmacological rationale and evidence
    • 69 Unger T, Culman J, Gohlke P. Angiotensin II receptor blockade and end-organ protection: pharmacological rationale and evidence. J Hypertens 1998; (suppl) 16:S3-S8.
    • (1998) J Hypertens , vol.16 , Issue.SUPPL.
    • Unger, T.1    Culman, J.2    Gohlke, P.3
  • 70
    • 0031045954 scopus 로고    scopus 로고
    • Enhanced expression of endothelin-1 gene in resistance arteries in severe human essential hypertension
    • 70 Schiffrin EL, Deng LY, Sventek P, Day R. Enhanced expression of endothelin-1 gene in resistance arteries in severe human essential hypertension. J Hypertens 1997; 15:57-63.
    • (1997) J Hypertens , vol.15 , pp. 57-63
    • Schiffrin, E.L.1    Deng, L.Y.2    Sventek, P.3    Day, R.4
  • 71
    • 0029967153 scopus 로고    scopus 로고
    • Enhanced expression of the endothelin-1 gene in blood vessels of DOCA-salt hypertensive rats: Correlation with vascular structure
    • 71 Schiffrin EL, Lariviere R, Li JS, Sventek P. Enhanced expression of the endothelin-1 gene in blood vessels of DOCA-salt hypertensive rats: correlation with vascular structure. J Vasc Res 1996; 33:235-248.
    • (1996) J Vasc Res , vol.33 , pp. 235-248
    • Schiffrin, E.L.1    Lariviere, R.2    Li, J.S.3    Sventek, P.4
  • 72
    • 0029583301 scopus 로고
    • Endothelin-1 gene expression and vascular hypertrophy in DOCA-salt hypertension compared to spontaneously hypertensive rats
    • 72 Schiffrin EL, Lariviere R, Li JS, Sventek P, Touyz RM. Endothelin-1 gene expression and vascular hypertrophy in DOCA-salt hypertension compared to spontaneously hypertensive rats. Clin Exp Pharmacol Physiol 1995; 22:5188-8190.
    • (1995) Clin Exp Pharmacol Physiol , vol.22 , pp. 5188-8190
    • Schiffrin, E.L.1    Lariviere, R.2    Li, J.S.3    Sventek, P.4    Touyz, R.M.5
  • 73
    • 0031959331 scopus 로고    scopus 로고
    • Endothelin A receptor blockade alleviates hypertension and renal lesions associated with chronic nitrix oxide synthase inhibition
    • 73 Verhagen AM, Rabelink TJ, Braam B, Ogenorth TJ, Grone HJ, Koomans HA, Joles JA. Endothelin A receptor blockade alleviates hypertension and renal lesions associated with chronic nitrix oxide synthase inhibition. J Am Soc Nephrol 1998; 9:755-762.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 755-762
    • Verhagen, A.M.1    Rabelink, T.J.2    Braam, B.3    Ogenorth, T.J.4    Grone, H.J.5    Koomans, H.A.6    Joles, J.A.7
  • 74
    • 0031900281 scopus 로고    scopus 로고
    • Nephroprotection of an ET(A)-receptor blocker (LU 135252) in salt-loaded uninephrectomized stroke-prone spontaneously hypertensive rats
    • 74 Orth SR, Esslinger JP, Amann K, Schwarz U, Raschack M, Ritz E. Nephroprotection of an ET(A)-receptor blocker (LU 135252) in salt-loaded uninephrectomized stroke-prone spontaneously hypertensive rats. Hypertension 1998; 31:995-1001.
    • (1998) Hypertension , vol.31 , pp. 995-1001
    • Orth, S.R.1    Esslinger, J.P.2    Amann, K.3    Schwarz, U.4    Raschack, M.5    Ritz, E.6
  • 75
    • 0033537665 scopus 로고    scopus 로고
    • Endothelin-1 and its mRNA in the wall layers of human arteries ex vivo
    • This study provides unequivocal evidence that components of the endothelin system including ECE, and endothelin mRNA and proteins are increased both in the endothelium as well as in the vascular smooth muscle in patients with hypertension and atherosclerosis
    • 75 Rossi GP, Colonna S, Pavan E, Albertin G, Della Rocca F, Gerosa G, Casarotto D, Sartore S, Pauletto P, Pessina AC. Endothelin-1 and its mRNA in the wall layers of human arteries ex vivo. Circulation 1999; 99:1147-1155. This study provides unequivocal evidence that components of the endothelin system including ECE, and endothelin mRNA and proteins are increased both in the endothelium as well as in the vascular smooth muscle in patients with hypertension and atherosclerosis.
    • (1999) Circulation , vol.99 , pp. 1147-1155
    • Rossi, G.P.1    Colonna, S.2    Pavan, E.3    Albertin, G.4    Della Rocca, F.5    Gerosa, G.6    Casarotto, D.7    Sartore, S.8    Pauletto, P.9    Pessina, A.C.10
  • 76
    • 0033042155 scopus 로고    scopus 로고
    • Different contributions of endothelin-A and endothelin-B receptors in the pathogenesis of deoxycorticosterone acetate-salt-induced hypertension in rats
    • 76 Matsumura Y, Hashimoto N, Taira S, Kuro T, Kitano R, Ohkita M, Opgenorth TJ, Takaoka M. Different contributions of endothelin-A and endothelin-B receptors in the pathogenesis of deoxycorticosterone acetate-salt-induced hypertension in rats. Hypertension 1999; 33:759-765.
    • (1999) Hypertension , vol.33 , pp. 759-765
    • Matsumura, Y.1    Hashimoto, N.2    Taira, S.3    Kuro, T.4    Kitano, R.5    Ohkita, M.6    Opgenorth, T.J.7    Takaoka, M.8
  • 77
    • 0031026198 scopus 로고    scopus 로고
    • Endothelins in the normal and diseased kidney
    • 77 Kohan DE. Endothelins in the normal and diseased kidney. Am J Kidney Dis 1997; 29:2-26.
    • (1997) Am J Kidney Dis , vol.29 , pp. 2-26
    • Kohan, D.E.1
  • 78
    • 0027203495 scopus 로고
    • A specific endothelin subtype A receptor antagonist protects against injury in renal disease progression
    • 78 Benigni A, Zoja C, Corna D, Orisio S, Longaretti L, Bertani T, Remuzzi G. A specific endothelin subtype A receptor antagonist protects against injury in renal disease progression. Kidney Int 1993; 44:440-444.
    • (1993) Kidney Int , vol.44 , pp. 440-444
    • Benigni, A.1    Zoja, C.2    Corna, D.3    Orisio, S.4    Longaretti, L.5    Bertani, T.6    Remuzzi, G.7
  • 79
    • 0032898256 scopus 로고    scopus 로고
    • Macrophage and myofibroblast involvement in ischemic acute renal failure is attenuated by endothelin receptor antagonists
    • 79 Forbes JM, Leaker B, Hewitson TD, Becker GJ, Jones CL. Macrophage and myofibroblast involvement in ischemic acute renal failure is attenuated by endothelin receptor antagonists. Kidney Int 1999; 55:198-208.
    • (1999) Kidney Int , vol.55 , pp. 198-208
    • Forbes, J.M.1    Leaker, B.2    Hewitson, T.D.3    Becker, G.J.4    Jones, C.L.5
  • 80
    • 0031058461 scopus 로고    scopus 로고
    • The renoprotective potential of endothelin receptor antagonists
    • 80 Begnini A, Remuzzi G. The renoprotective potential of endothelin receptor antagonists. Exp Opin Ther Patents 1997; 7:139-149.
    • (1997) Exp Opin Ther Patents , vol.7 , pp. 139-149
    • Begnini, A.1    Remuzzi, G.2
  • 81
    • 0031040565 scopus 로고    scopus 로고
    • Endothelial function and the kidney. An emerging target for cardiovascular therapy
    • 81 Rabelink TJ, Koomans HA. Endothelial function and the kidney. An emerging target for cardiovascular therapy. Drugs 1997; 53 (suppl. 1):11-19.
    • (1997) Drugs , vol.53 , Issue.SUPPL. 1 , pp. 11-19
    • Rabelink, T.J.1    Koomans, H.A.2
  • 82
    • 0032958019 scopus 로고    scopus 로고
    • The ETA receptor blocker LU 135252 prevents chronic transplant nephropathy in the 'Fisher to Lewis' model
    • A-receptor antagonism inhibits transplant vasculopathy and glomerular injury independently from immunosuppression in rats
    • A-receptor antagonism inhibits transplant vasculopathy and glomerular injury independently from immunosuppression in rats.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 387-391
    • Orth, S.R.1    Odoni, G.2    Amann, K.3    Strzelczyk, P.4    Raschack, M.5    Ritz, M.6
  • 83
    • 0028053857 scopus 로고
    • Age-dependent glomerular damage in the rat
    • 83 Baylis C. Age-dependent glomerular damage in the rat. J Clin Invest 1994; 94:1823-1829.
    • (1994) J Clin Invest , vol.94 , pp. 1823-1829
    • Baylis, C.1
  • 84
    • 0000382540 scopus 로고    scopus 로고
    • Aging, a cardiovascular risk factor, markedly increases expression of endothelin-1 in vivo independent of blood pressure and endothelin-1 clearance
    • 84 Barton M, Lattmann T, Shaw S, Lüscher TF. Aging, a cardiovascular risk factor, markedly increases expression of endothelin-1 in vivo independent of blood pressure and endothelin-1 clearance. J Am Coll Cardiol 1999; 33 (suppl. A):225.
    • (1999) J Am Coll Cardiol , vol.33 , Issue.SUPPL. A , pp. 225
    • Barton, M.1    Lattmann, T.2    Shaw, S.3    Lüscher, T.F.4
  • 85
    • 0029928217 scopus 로고    scopus 로고
    • Blocking both type A and B endothelin receptors in the kidney attenuates renal injury and prolongs survival in rats with remnant kidney
    • 85 Benigni A, Zola C, Corna D, Orisio S, Facchinetti D, Benati L, Remuzzi G. Blocking both type A and B endothelin receptors in the kidney attenuates renal injury and prolongs survival in rats with remnant kidney. Am J Kidney Dis 1996; 27:416-423.
    • (1996) Am J Kidney Dis , vol.27 , pp. 416-423
    • Benigni, A.1    Zola, C.2    Corna, D.3    Orisio, S.4    Facchinetti, D.5    Benati, L.6    Remuzzi, G.7
  • 86
    • 0031606120 scopus 로고    scopus 로고
    • Endothelin-A receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats
    • 86 Kassab S, Miller MT, Novak J, Reckelhoff J, Clower B, Granger JP. Endothelin-A receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats. Hypertension 1998; 31:397-402.
    • (1998) Hypertension , vol.31 , pp. 397-402
    • Kassab, S.1    Miller, M.T.2    Novak, J.3    Reckelhoff, J.4    Clower, B.5    Granger, J.P.6
  • 87
    • 0031941152 scopus 로고    scopus 로고
    • Prevention of the cardiovascular and renal effects of angiotensin II by endothelin blockade
    • 87 Herizi A, Jover B, Bouriquet N, Mimran A. Prevention of the cardiovascular and renal effects of angiotensin II by endothelin blockade. Hypertension 1998; 31:10-14.
    • (1998) Hypertension , vol.31 , pp. 10-14
    • Herizi, A.1    Jover, B.2    Bouriquet, N.3    Mimran, A.4
  • 88
    • 0032948745 scopus 로고    scopus 로고
    • Early-onset but not late-onset endothelin-A-receptor blockade can modulate hypertension, cerebral edema, and proteinuria in stroke-prone hypertensive rats
    • 88 Blezer EL, Nicolay K, Goldschmeding R, Jansen GH, Koomans HA, Rabelink TJ, Joles JA. Early-onset but not late-onset endothelin-A-receptor blockade can modulate hypertension, cerebral edema, and proteinuria in stroke-prone hypertensive rats. Hypertension 1999; 33:137-144.
    • (1999) Hypertension , vol.33 , pp. 137-144
    • Blezer, E.L.1    Nicolay, K.2    Goldschmeding, R.3    Jansen, G.H.4    Koomans, H.A.5    Rabelink, T.J.6    Joles, J.A.7
  • 89
    • 84900560029 scopus 로고    scopus 로고
    • Dysfunctional renal nitric oxide synthase and increased endothelin-1 in Dahl salt-sensitive hypertension. Modulation by chronic ETA receptor blockade
    • 89 Barton M, d'Uscio LV, Shaw S, Vos I, Rabelink T, Lattman T, Lüscher F. Dysfunctional renal nitric oxide synthase and increased endothelin-1 in Dahl salt-sensitive hypertension. Modulation by chronic ETA receptor blockade. Hypertension 1998; 32:623.
    • (1998) Hypertension , vol.32 , pp. 623
    • Barton, M.1    D'Uscio, L.V.2    Shaw, S.3    Vos, I.4    Rabelink, T.5    Lattman, T.6    Lüscher, F.7


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