Angiotensin II increases tissue endothelin and induces vascular hypertrophy: Reversal by ET(A)-receptor antagonist

Circulation

Volumn 96, Issue 5, 1997, Pages 1593-1597

  Moreau, Pierre ^b   D'Uscio, Livius V ^b   Shaw, Sidney ^a   Takase, Hiroyuki ^b   Barton, Matthias ^b   Lüscher, Thomas F ^b  

^a BERN UNIVERSITY HOSPITAL   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Angiotensin; Arteries; Endothelin; Receptors

Indexed keywords

ANGIOTENSIN; ENDOTHELIN; ENDOTHELIN A RECEPTOR ANTAGONIST; RENIN;

ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL TONE; BLOOD VESSEL WALL; CELL PROLIFERATION; CONTROLLED STUDY; HYPERTENSION; HYPERTROPHY; MESENTERIC ARTERY; MESENTERY BLOOD FLOW; NONHUMAN; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; TUNICA MEDIA; VASCULAR DISEASE;

EID: 0030776737     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.96.5.1593     Document Type: Article

References (23)

1. Lüscher TF. Local relaxant and constricting factors in the vessel wall. In: Swales JD, ed. Textbook of Hypertension. London, UK: Blackwell Scientific Publications; 1994:145-159.
2. Hirata Y, Takagi Y, Fukuda Y, Marumo F. Endothelin is a potent mitogen for rat vascular smooth muscle cells. Atherosclerosis. 1989;78:225-228.
3. Dubin D, Pratt RE, Cooke JP, Dzau VJ. Endothelin, a potent vasoconstrictor, is a vascular smooth muscle mitogen. J Vasc Med Biol. 1989;1:13-17.
4. Chua BHL, Krebs CJ, Chua CC, Diglio CA. Endothelin stimulates protein synthesis in smooth muscle cells. Am J Physiol. 1992;262:E412-E416.
5. Larivière R, Day R, Schiffrin EL. Increased expression of endothelin-1 gene in blood vessels of deoxycorticosterone acetate-salt hypertensive rats. Hypertension. 1993;21:916-920.
6. Li JS, Larivière R, Schiffrin EL. Effect of a nonselective endothelin antagonist on vascular remodeling in deoxycorticosterone acetate-salt hypertensive rats: evidence for a role of endothelin in vascular hypertrophy. Hypertension. 1994;24:183-188.
7. Heistad DD, Baumbach GL. Cerebral vascular changes during chronic hypertension: good guys and bad guys. J Hypertens. 1992; 10(suppl 7):S71-S75.
8. Heagerty AM, Aalkjaer C, Bund SJ, Korsgaard N, Mulvany MJ. Small artery structure in hypertension: dual process of remodeling and growth. Hypertension. 1993;21:391-397.
9. Mulvany MJ, Baumbach GL, Aalkjaer C, Heagerty AM, Korsgaard N, Schiffrin EL, Heistad DD. Vascular remodeling. Hypertension. 1996;28:505-506. Letter.
10. Griffin SA, Brown WCB, Macpherson F, McGrawth JC, Wilson VG, Korsgaard N, Mulvany MJ, Lever AF. Angiotensin II causes vascular hypertrophy in part by a non-pressor mechanism. Hypertension. 1991;17:626-635.
11. Dohi Y, Hahn AWA, Boulanger CM, Bühler FR, Lüscher TF. Endothelin stimulated by angiotensin II augments contractility of spontaneously hypertensive rat resistance arteries. Hypertension. 1992;19:131-137.
12. Imai T, Hirata Y, Emori T, Yanagisawa M, Masaki T, Marumo F. Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells. Hypertension. 1992;19:753-757.
13. Takase H, Moreau P, Küng CF, Nava E, Lüscher TF. Antihypertensive therapy improves the endothelial function of resistance arteries in nitric oxide deficient hypertension: effect of verapamil and trandolapril. Hypertension. 1996;27:25-31.
14. Raschack M, Unger L, Riechers H, Klinge D. Receptor selectivity of endothelin antagonists and prevention of vasoconstriction and endothelin-induced sudden death. J Cardiovasc Pharmacol. 1995; 26(suppl 3):S397-S399.
15. 14a. Hisaki K, Matsumura Y, Maekawa H, Fujita K, Takaoka M, Morimoto S. Conversion of big ET-1 in the rat lung: role of phosphoramidon-sensitive endothelin-1-converting enzyme. Am J Physiol. 1994;266:H422-H428.
16. Moreau P, Takase H, Küng CF, Shaw S, Lüscher TF. Chronic endothelin-receptor blockade in chronic nitric oxide deficient hypertension. Hypertension. 1997;29:763-769.
17. Moreau P, Takase H, Küng CF, van Rooijen M-M, Schaffner T, Lüscher TF. Structure and function of the rat basilar artery during chronic nitric oxide synthase inhibition. Stroke. 1995;26:1922-1929.
18. Wallenstein S, Zucker CL, Fleiss JL. Some statistical methods useful in circulation research. Circ Res. 1980;47:1-9.
19. Baumbach GL, Heistad DD. Remodeling of cerebral arterioles in chronic hypertension. Hypertension. 1989;13:968-972.
20. Li JS, Knafo L, Turgeon A, Garcia R, Schiffrin EL. Effect of endothelin antagonism on blood pressure and vascular structure in renovascular hypertensive rats. Am J Physiol. 1996;40:H88-H93.
21. Chen L, McNeill JR, Wilson TW, Gopalakrishnan V. Heterogeneity in vascular smooth muscle responsiveness to angiotensin II: role of endothelin. Hypertension. 1995;26:83-88.
22. Li J-S, Schiffrin EL. Effect of chronic treatment of adult spontaneously hypertensive rats with an endothelin receptor antagonist. Hypertension. 1995;25:495-500.
23. Potter GS, Melaragno MG, Johnson RJ, Fink GD. Evidence for a role of endothelin in the hypertension of experimental chronic renal failure. Hypertension. 1996;28:542. Abstract.