Mutational response at the splenic T-lymphocyte hprt locus in mice treated as neonates: Contrasting effects of the carcinogens N-ethyl-N-nitrosourea, dimethylnitrosamine, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

Environmental and Molecular Mutagenesis

Volumn 31, Issue 3, 1998, Pages 243-247

  Dass, S Balachandra ^a,b   Heflich, Robert H ^a   Casciano, Daniel A ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b NCTR ^*  (United States)

Author keywords

2 amino 1 methyl 6 phenylimidazo 4,5 b pyridine; Dimethylnitrosamine; hprt; N ethyl N nitrosourea; Neonatal mice; T lymphocyte mutation

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; CARCINOGEN; DIMETHYLNITROSAMINE; ETHYLNITROSOUREA; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BIOASSAY; CARCINOGENICITY; CONTROLLED STUDY; DRUG COMPARISON; ENZYME ACTIVITY; FEMALE; GENE LOCUS; MALE; MUTATION; NONHUMAN; SPLEEN; T LYMPHOCYTE;

ALKYLATING AGENTS; ANIMALS; ANIMALS, NEWBORN; CARCINOGENS; CELLS, CULTURED; DIMETHYLNITROSAMINE; DNA DAMAGE; ETHYLNITROSOUREA; FALSE NEGATIVE REACTIONS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; IMIDAZOLES; MALE; MICE; MICE, INBRED C57BL; MUTAGENICITY TESTS; SPLEEN; T-LYMPHOCYTES;

ANIMALIA; RODENTIA;

EID: 0031965525     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2280(1998)31:3<243::AID-EM5>3.0.CO;2-L     Document Type: Article

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