Comparison of induction of hprt mutations by 1,3-butadiene and/or its metabolites 1,2-epoxybutene and 1,2,3,4-diepoxybutane in lymphocytes from spleen of adult male mice and rats in vivo

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 397, Issue 1, 1998, Pages 21-36

  Tates, A D ^a   Van Dam, F J ^a   Van Teylingen, C M M ^a   De Zwart, F A ^a   Zwinderman, A H ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

1,2,3,4 Diepoxybutane; 1,2 Epoxybutene; 1,3 Butadiene; hprt mutation; Lymphocyte; Mouse; Rat

Indexed keywords

1,3 BUTADIENE; 1,3 BUTADIENE DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL TRANSFORMATION; DRUG EFFECT; GENE EXPRESSION REGULATION; LYMPHOCYTE; MOUSE; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SPLEEN CELL; WATER CONTAMINATION;

AGE FACTORS; ANIMALS; BUTADIENES; CELLS, CULTURED; CLONE CELLS; ENZYME INDUCTION; EPOXY COMPOUNDS; ETHYLNITROSOUREA; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LYMPHOCYTES; MALE; MICE; MICE, INBRED STRAINS; MUTAGENS; MUTATION; RATS; RATS, INBRED LEW; SPLEEN;

ANIMALIA;

EID: 0032536123     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(97)00192-9     Document Type: Article

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