Inhibition of thymidylate synthase by pergularinine, tylophorinidine and deoxytubulosine

Indian Journal of Biochemistry and Biophysics

Volumn 36, Issue 6, 1999, Pages 442-448

  Narasimha Rao, K ^a   Bhattacharya, R K ^a   Veankatachalam, S R ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; DRUG DERIVATIVE; EMETINE; ENZYME INHIBITOR; ISOQUINOLINE DERIVATIVE; PERGULARININE; THYMIDYLATE SYNTHASE; TUBULOSINE; TYLOPHORINIDINE;

ARTICLE; BLOOD; DRUG ANTAGONISM; ENZYMOLOGY; HUMAN; NEOPLASM;

ALKALOIDS; EMETINE; ENZYME INHIBITORS; HUMANS; ISOQUINOLINES; NEOPLASMS; THYMIDYLATE SYNTHASE;

EID: 0033288147     PISSN: 03011208     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Friedkin M (1973) in Advances in Enymology and Related Areas of Molecular Biology (Meister A ed), Vol 38, pp 235-292, John Wiley & Sons, New York
2. Blakley RL (1969) in The Biochemistry of Folic Acid and Related Pteridines (Neuberger A & Tatum EL, eds), pp 219-266, North Holland Publishing Company, Amsterdam
3. nd edn, pp 53-100, WH Freeman and Company, New York
4. Langenbach R (1976) Biochim Biophys Acta 422, 295-301
5. Herzfeld A & Raper SM (1980) Cancer Res 40, 744-750
6. Navalgund LG, Rossana C, Muench AJ & Johnson LE (1980) J Biol Chem 255, 7386-7390
7. Danenberg PV (1977) Biochim Biophys Acta 473, 73-92
8. Torotoglou N & Pazdur R (1996) Clin Cancer Res 2, 227-243
9. Dunlap RB, Harding RGL & Huennekens FM (1971) Biochemistry 10, 88-97
10. Crusberg TC, Leary R & Kisliuk RL (1970) J Biol Chem 245, 5292-5296
11. Narasimha Rao K & Kisliuk RL (1983) Proc Nat Acad Sci USA 80, 916-920
12. Narasimha Rao K, Kisliuk RL, Gaumont Y, Deschnes R, Vestal K, Karasik M, Maley GF, Nair MG & Baugh CM (1983) in Chemistry and Biology of Pteridines (Blair JA, ed), pp 375-379, Walter de Gruyter & Co, Berlin
13. Narasimha Rao K & Kisliuk RL (1986) Indian J Microbiol 26, 105-110
14. Narasimha Rao K (1993) Indian J Biochem Biophys 30, 26-35
15. Chu E & Allegra J (1996) BioEssays 18, 191-198
16. Carreras CW & Santi DV (1995) Annu Rev Biochem 64, 721-762
17. Shoichet BK, Stroud RM, Santi DV, Kuntz ID & Perry KM (1993) Science 259, 1445-1450
18. Mulchandani NB & Venkatachalam SR (1976) Phytochemistry 15, 1561-1563
19. Venkatachalam SR, Kunjappu JT & Nair CKK (1994) Indian J Chem 33 B, 809-811
20. Narasimha Rao K, Bhattacharya RK & Venkatachalam SR (1996) Presented in part at the Indian Society of Cell Biology: XIX All India Cell Biology Conference and Cell Biology Symposia Proceedings, Calcutta PNA-20, pp 68-69
21. Narasimha Rao K, Bhattacharya RK & Venkatachalam SR (1997) Presented in part at the XXIV Annual Conference of the Association of Clinical Biochemists of India, Calcutta, ACBI Symposium Proceedings OP-CA-I, pp 36
22. Wiegrebe W, Kramer WJ & Shamma M (1984) J Nat Prod 47, 397-408 and the references therein
23. Lomax MI & Greenberg GR (1967) J Biol Chem 242, 109-113
24. Lowry OH, Rosebrough NJ, Farr AL & Randall RJ (1951) J Biol Chem 193, 265-275
25. Bertino JR, Silber R, Freeman M, Alenty A, Albrecht M, Gabrio BW & Huennekens FM (1963) J Clin Invest 42, 1899-1907
26. Tothunter (1979) Methods Enzymol 63, 383-411
27. Fromm HJ (1979) Methods Enzymol 63, 467-486
28. Narasimha Rao K, Bhattacharya RK & Venkatachalam SR (1997) Chem-Biol Interact 106, 201-211
29. Narasimha Rao K, Bhattacharya RK & Venkatachalam SR (1998) J Biochem Mol Toxicol 12, 167-173
30. Narasimha Rao K, Bhattacharya RK & Venkatachalam SR (1998) Cancer Lett 128, 183-188
31. Narasimha Rao K, Bhattacharya RK & Venkatachalam SR (1998) Anti-Cancer Drugs, 9, 727-732
32. Doglas KT (1987) Med Res Rev, 7, 441-475
33. Costi MP, Tondi D, Rinaldi M, Barlacco D, Cignarella G, Santi DV, Musiu C, Pudu I, Vacca G & La Colla P (1996) Eur J Med Chem 31, 1011-1016
34. Hyatt DC, Maley F & Montfort WR (1997) Biochemistry 36, 4585-4594
35. Chen CH, Davis RA & Maley F (1996) Biochemistry 35, 8786-8793
36. Hanlon MH & Ferone R (1996) Cancer Res 56, 3301-3306
37. Hagen RL, Hynes JB, Pimsler M & Kisliuk RL (1995) Biochem Pharmacol 50, 803-809
38. Santi DV, McHenry CS & Perriard ER (1974) Biochemistry 13, 467-470
39. Narasimha Rao K (1993) Indian J Biochem Biophys 30, 103-110
40. Narasimha Rao K (1994) Indian J Biochem Biophys 31, 184-190
41. Varney MD, Palmer CL, Deal JG, Webber S, Welsh KM, Bartlett CA, Morse CA, Smith WW & Janson CA (1995) J Med Chem 38, 1892-1903
42. Gangjee A, Mavandadi F, Queener SF & McGuire JJ (1995) J Med Chem 38, 2158-2165
43. Lockshin A, Moran HG & Danenberg PV (1979) Proc Nat Acad Sci USA 76, 750-754
44. Dolnick BJ & Cheng Y-c (1977) J Biol Chem 252, 7697-7703
45. Silber R, Gabrio BW & Huennekens FM (1963) J Clin Invest 42, 1913-1921
46. Larsson P-A, Carlsson G, Gustavsson B & Spears CP (1996) Acta Oncol 35, 469-472
47. Hallek M, Wanders L, Ostwald M, Busch R, Senekowitsch R, Stern S, Schick H-D, Hallek IK & Emmerich B (1996) Leuk Lymphoma 22, 439-447
48. Bick IRC & Sinchai W (1981) in The Alkaloids: Chemistry and Physiology (Rodrigo RGA ed), Vol XIX, pp 193-220, Academic Press Inc, New York
49. Huang M-T & Grollman AP (1972) Mol Pharmacol, 8, 538-550
50. Grant P, Sánchez L & Jiménez A (1974) J Bacteriol 120, 1308-1314
51. Mathé G, Hayat E, Chenu E, Husson HP, Thevenet T, Kan C & Potier P (1978) Cancer Res 38, 1465-1467
52. Grollman AP (1967) Science 157, 84-85
53. Grollman AP (1966) Proc Nat Acad Sci USA 56, 1867-1874
54. Bhutani KK, Sharma GL & Ali M (1987) Planta Med 53, 532-536