Suppression of matrix metalloproteinase-3 synthesis by interleukin-4 in human articular chondrocytes

Journal of Rheumatology

Volumn 24, Issue 9, 1997, Pages 1774-1779

  Nemoto, Osamu ^a,d   Yamada, Harumoto ^a   Kikuchi, Toshiyuki ^a   Shimmei, Masayuki ^a   Obata, Ken'ichi ^b   Sato, Hiroshi ^c   Seiki, Motoharu ^c  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^b FUJI CHEMICAL INDUSTRIES LTD   (Japan)

^c KANAZAWA UNIVERSITY   (Japan)

^d Department of Orthopaedic Surgery ^*  (Japan)

Author keywords

Human articular chondrocytes; Interleukin 4; Matrix metalloproteinase 3

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 4; MESSENGER RNA; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE;

ADULT; ARTICLE; CARTILAGE CELL; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; MONOLAYER CULTURE; NORMAL HUMAN; NORTHERN BLOTTING; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION;

ADULT; CARTILAGE, ARTICULAR; CELL DIVISION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOPROTEINS; GROWTH SUBSTANCES; HUMANS; INTERLEUKIN-1; INTERLEUKIN-4; MATRIX METALLOPROTEINASE 3; METALLOENDOPEPTIDASES; PROTEASE INHIBITORS; RNA, MESSENGER; TISSUE INHIBITOR OF METALLOPROTEINASES;

EID: 0030868582     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Mankin HJ, Dorfman H, Lippiello L, Zarins A: Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg 1972;53A:523-37.
2. Brandt KD: Enhanced extractability of articular cartilage proteoglycans in osteoarthritis. Biochem J 1974;143:475-83.
3. Ballet AJ, Nance JL: Biochemical findings in normal and osteoarthritic cartilage. II. Chondroitin sulfate concentration and chain length, water and ash content. J Clin Invest 1966;45:1170-7.
4. Mankin AJ, Lippiello L: The glysaminoglycans of normal and arthritic cartilage. J Clin Invest 1971;50:1712-9.
5. Nguyen Q, Murphy G, Roughly PJ, Mort JS: Degeneration of proteoglycan aggregate by a cartilage metalloproteinase. Evidence for the involvement of stromelysin in the degradation of link protein heterogeneity in situ. Biochem J 1989;259:61-7.
6. Dean DD, Martel-Pelletier J, Pelletier J-P, Howell DS, Woessner JF Jr: Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage. J Clin Invest 1989;84:678-85.
7. Martel-Pelletier J, Pelletier J-P, Cloutier J-M, Howell DS, Ghandur-Mnaymneh L, Woessner JF Jr: Neutral proteases capable of proteoglycan digesting activity in osteoarthritic and normal human cartilage. Arthritis Rheum 1984;27:305-12.
8. Martel-Pelletier J, Pelletier J-P, Malemud CJ: Activation of neutral metalloproteinase in human osteoarthritic knee cartilage: Evidence for degradation in the core protein of sulfated proteoglycan. Ann Rheum Dis 1988;47:801-8.
9. Mehraban F, Kuo SY, Riera H, Chang C, Moskowitz RW: Prostromelysin and procollagenase genes are differentially up-regulated in chondrocytes from the knees of rabbits with experimental osteoarthritis. Arthritis Rheum 1994;31:1189-97.
10. Okada Y, Shinmei M, Tanaka O, et al: Localization of matrix metalloproteinase 3 in osteoarthritic cartilage and synovium. Lab Invest 1992;66:680-90.
11. Cawston TE, Curry VA, Clark IM, Hazleman BL: Identification of a new metalloproteinase inhibitor that forms tight-binding complexes with collagenase. Biochem J 1990;269:183-7.
12. Boone TC, Johnson MJ, De Clerck YA, Langley KE: cDNA cloning and expression of a metalloproteinase inhibitor related to tissue inhibitor of metalloproteinases. Proc Natl Acad Sci USA 1990;87:2800-4.
13. Stetler-Stevenson WG, Krutzsch HC, Liotta LA: Tissue inhibitor of metalloproteinase. A new member of the metalloproteinase inhibitor family. J Biol Chem 1989;264:17374-8.
14. Goldberg GI, Marmer BL, Grant GA, Eisen AZ, Wilhelm S, He CS: Human 72-kilodalton type IV collagenase forms complex with a tissue inhibitor of metalloproteinases designated TIMP-2. Proc Natl Acad Sci USA 1989;86:8207-11.
15. Martel-Pelletier J, McCollum R, Fujimoto N, Obata K, Cloutier J-M, Pelletier J-P: Excess of metalloproteinases over tissue inhibitor of metalloproteinases may contribute to cartilage degradation in osteoarthritis and rheumatoid arthritis. Lab Invest 1994;70:807-15.
16. Lefebvre V, Peters-Joris C, Vaes G: Modulation by interleukin-1 and tumor necrosis factor a of production of collagenase, tissue inhibitor of metalloproteinase and collagen types in differentiated and dedifferentiated articular chondrocytes. Biochem Biophys Acta 1990;1052:366-78.
17. Martel-Pelletier J, Zafarullah M, Kodama S, Pelleyier JP: In vitro effects of interleukin-1 on the synthesis of metalloproteases, TIMP, plasminogen activators and inhibitors in human articular cartilage. J Rheumatol 1991;(suppl 27)18:80-4.
18. Shinmei M, Masuda K, Kikuchi T, Shimomura Y: Interleukin-1, tumor necrosis factor, and interleukin-6 as mediators of cartilage destruction. Semin Arthritis Rheum 1989;(suppl 1)18:27-32.
19. Fontana A, Hengartner H, Weber E, Fehr K, Grob PJ, Cohen G: Interleukin-1 activity in the synovial fluid of patients with rheumatoid arthritis. Rheumatol Int 1982;2:49-53.
20. Verschure PL, van Noorden GJF: The effect of interleukin-1 on articular cartilage destruction as observed in arthritic diseases, and its therapeutic control. Clin Exp Rheumatol 1990;2:49-53.
21. Pujol JP, Loyau G: Interleukin-1 and osteoarthritis. Life Sci 1987;41:1187-98.
22. Sandy JD, Barrach HJ, Flannery CR, Plass AHK: The biosynthetic response of the mature chondrocyte in early osteoarthritis. J Rheumatol 1987;(suppl 14)14:16-9.
23. Tyler JA, Articular cartilage cultured with catabolin (pig interleukin-1) synthesizes a decreased number of normal proteoglycan molecules. Biochem J 1985;227:869-78.
24. Ikebe T, Hirata M, Kogat T: Human recombinant interleukin-1 mediated suppression of glycosaminoglycan synthesis in cultured rat costal chondrocytes. Biochem Biophys Res Commun 1986;140:386-91.
25. Howard M, John F, Hilfiker M, et al: Identification of a T cell-derived B cell growth factor distinct from interleukin-2. J Exp Med 1982;155:914-23.
26. Teveide AA, Huijbens RJF, Heije K, de Vries Je, Figdor CG: Interleukin-4 (IL-4) inhibits secretion of IL-1β. tumor necrosis factor α, and IL-6 by human monocytes. Blood 1990;76:1392-7.
27. 2. Proc Natl Acad Sci USA 1989;86:3803-7.
28. Miossec P, Briolay J, Dechanet J, Wijdenes J, Martinez-Valdez H, Banchereau J: Inhibition of the production of proinflammatory cytokines and immunoglobulins by interleukin-4 in an ex vivo model of rheumatoid synovitis. Arthritis Rheum 1992;35:874-83.
29. Suzuki H, Sugiyama E, Tunru I, et al: Suppressive effect of interleukin-4 (IL-4) on IL-6 production by adherent rheumatoid synovial cells. Clin Immunol Immunopathol 1993;66:67-72.
30. Obata K, Iwata K, Okada Y, Kohrin T, Ohuchi E, Yoshida S: A one step sandwich enzyme immunoassay for human matrix metalloproteinase 3 (stromelysin) using monoclonal antibodies. Clin Chim Acta 1992;211:59-72.
31. Kodama S, Iwata K, Iwata H, Yamashita K, Hayakawa T: Rapid one-step sandwich enzyme immunoassay for tissue inhibitor of metalloproteinase. An application for rheumatoid arthritis serum and plasma. J Immunol Methods 1990;127:103-8.
32. Twinning SS: Fluorescein isthiocyanate-labeled casein assay for proteolytic enzymes. Anal Biochem 1984;143:30-4.
33. Chomczynski P, Succhi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-9.
34. Sato H, Kida Y, Mai M, et al: Expression of genes encoding type IV collagen-degrading metalloproteinases and tissue inhibitors of metalloproteinases in various human tumor cells. Oncogene 1992;7:77-83.
35. Shinmei M, Masuda K, Kikuchi T, Okada Y: Production of cytokines by chondrocytes and its role in proteoglycan degradation. J Rheumatol 1991:(suppl 27)18:89-91.
36. Hasty KA, Reife RA, Kang AH, Stuart JM: The role of stromelysin in the cartilage destruction that accompanies inflammatory arthritis. Arthritis Rheum 1990;33:388-97.
37. Nguyen Q, Mort JS, Roughly PJ: Preferential mRNA expression of prostromelysin relative to procollagenase and in situ localization in human articular cartilage. J Clin Invest 1992;89:1189-97.
38. Yeh LA, Augustine AJ, Lee P, Riviere LR, Sheldon A: Interleukin-4, an inhibitor of cartilage breakdown in bovine articular cartilage explants. J Rheumatol 1995;22:1740-6.
39. Shingu M, Miyauchi S, Nagai Y, Yasutake C, Horie K: The role of IL-4 and IL-6 in IL-1 dependent cartilage matrix degradation. Br J Rheumatol 1995;34:101-6.
40. Wong HL, Costa GL, Lotze MT, Wahl SM: Interleukin (IL)-4 differentially regulates monocyte IL-1 family gene expression and synthesis in vitro and in vivo. J Exp Med 1993;177:775-81.
41. Orino E, Sone S, Nii A, Ogura T: IL-4 upregulates IL-1 receptor antagonist gene expression and its production in human blood monocytes. J Immunol 1992;149:925-32.