Substrate selection by transporters associated with antigen processing occurs during peptide binding to TAP

Molecular Immunology

Volumn 35, Issue 8, 1998, Pages 427-433

  Gubler, Brigitte ^a   Daniel, Soizic ^a   Armandola, Elena A ^b   Hammer, Juergen ^c   Caillat Zucman, Sophie ^a   Van Endert, Peter M ^a  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c ROCHE MILANO RICERCHE   (Italy)

Author keywords

Binding assay; MHC; Peptide; TAP

Indexed keywords

CARRIER PROTEIN; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING; UNCLASSIFIED DRUG;

ANTIGEN PRESENTATION; ARTICLE; CARBOXY TERMINAL SEQUENCE; INSECT; MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING;

ALLELES; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTIGEN PRESENTATION; BINDING SITES; CARRIER PROTEINS; HUMANS; PEPTIDES; PROTEIN BINDING; RATS; SPODOPTERA;

EID: 0031715093     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(98)00059-5     Document Type: Article

References (24)

1. Androlewicz, M. J., Anderson, K. S., Cresswell, P., 1993. Evidence that transporters associated with antigen processing translocate a major histocompatibility complex class I-binding peptide into the endoplasmic reticulum in an ATP-dependent manner. Proc. Natl. Acad. Sci. U.S.A. 90, 9130-9134.
2. Androlewicz, M. J., Cresswell, P., 1994. Human transporters associated with antigen processing possess a promiscuous peptide-binding site. Immunity 1, 7-14.
3. Androlewicz, M. J., Cresswell, P., 1996. How selective is the transporter associated with antigen processing? Immunity 5, 1-5.
4. Armandola, E. A., Momburg, F., Nijenhuis, M., Bulbuc, N., Früh, K., Hämmerling, G. J., 1996. A point mutation in the human transporter associated with antigen processing (TAP2) alters the peptide transport specificity. Eur. J. Immunol. 26, 1748-1755.
5. Daniel, S., Caillat-Zucman, S., Hammer, J., Bach, J. F., van Endert, P. M., 1997. Absence of functional relevance of human transporter associated with antigen processing polymorphism for peptide selection. J. Immunol. 159, 2350-2357.
6. Daniel, S., Brusic, V., Caillat-Zucman, S., Petrovsky, N., Harrison, L., Riganelli, D., Sinigaglia, F., Gallazzi, F., Hammer, J., van Endert, P. M., 1998. Relationship between peptide selectivities of human transporters associated with antigen processing and HLA class I molecules. J. Immunol. 767, 617-624.
7. Heemels, M.-T., Ploegh, H. L., 1994. Substrate specificity of allelic variants of the TAP peptide transporter. Immunity 1, 775-784.
8. Heemels, M.-T., Schuhmacher, T. N. M., Wonigeit, K., Ploegh, H. L., 1993. Peptide translocation by variants of the transporter associated with antigen processing. Science 262, 2059-2063.
9. Koopmann, J. O., Post, M., Neefjes, J. J., Hämmerling, G. J., Momburg, F., 1996. Translocation of long peptides by transporters associated with antigen processing (TAP). Eur. J. Immunol. 26, 1720-1728.
10. Lehner, P. J., Cresswell, P., 1996. Processing and delivery of peptides presented by MHC class I molecules. Curr. Opin. Immunol. 8, 59-67.
11. Momburg, F., Roelse, J., Howard, J. C., Butcher, G. W., Hämmerling, G. J., Neefjes, J. J., 1994. Selectivity of MHC-encoded peptide transporters from human, mouse and rat. Nature 367, 648-651.
12. Neefjes, J., Gottfried, E., Roelse, J., Grommé, M., Obst, R., Hämmerling, G. J., Momburg, F., 1995. Analysis of the fine specificity of rat, mouse and human TAP peptide transporters. Eur. J. Immunol. 25, 1133-1136.
13. Neefjes, J. J., Momburg, F., Hämmerling, G. J., 1993. Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter. Science 261, 769-771.
14. Neisig, A., Roelse, J., Sijts, A. J. A. M., Ossendorp, F., Feltkamp, M. C. W., Kast, W. M., Melief, C. J. M., Neefjes, J. J., 1995. Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences. J. Immunol. 154, 1273-1279.
15. Nijenhuis, M., Schmitt, S., Armandola, E., Obst, R., Brunner, J., Hämmerling, G. J., 1996. Identification of a contact region for peptide on the TAP1 chain of the transporter associated with antigen processing. J. Immunol. 156, 2186-2195.
16. Obst, R., Armandola, E., Nijenhuis, M., Momburg, F., Hämmerling, G. J., 1995. TAP polymorphism does not influence transport of peptide variants in mice and humans. Eur. J. Immunol. 25, 2170-2176.
17. Ortmann, B., Copeman, J., Lehner, P. J., Sadasivan, B., Herberg, J. A., Grandea, A. G., Riddell, S. R., Tampe, R., Spies, T., Trowsdale, J., Cresswell, P., 1997. A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes. Science 277, 1306-1309.
18. Powis, S. J., Deverson, E. V., Coadwell, W. J., Ciruela, A., Huskisson, N. S., Smith, H., Butcher, G. W., Howard, J. C., 1992. Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule. Nature 357, 211-215.
19. Powis, S. J., Young, L. L., Joly, E., Barker, P. J., Richardson, L., Brandt, R. P., Melief, C. J., Howard, J. C., Butcher, G. W., 1996. The rat cim effect: TAP allele-dependent changes in a class I MHC anchor motif and evidence against C-terminal trimming of peptides in the ER. Immunity 4, 159-166.
20. Rammensee, H. G., Friede, T., Stefanoviç, S., 1995. MHC ligands and peptide binding motifs: first listing. Immunogenetics 41, 178-228.
21. Schumacher, T. N., Kantesaria, D. V., Serreze, D. V., Roopenian, D. C., Ploegh, H. L., 1994. Transporters from H-2b, H-2d, H-2s, H-2k, and H-2g7 (NOD/Lt) haplotype translocate similar sets of peptides. Proc. Natl. Acad. Sci. U.S.A. 91, 13004-13008.
22. Srivastava, P. K., Udono, H., Blachere, N. E., Li, Z., 1994. Heat shock proteins transfer peptides during antigen processing and CTL priming. Immunogenetics 39, 93-98.
23. Van Endert, P. M., Riganelli, D., Greco, G., Fleischhauer, K., Sidney, J., Sette, A., Bach, J.-F., 1995. The peptide-binding motif for the human transporter associated with antigen processing. J. Exp. Med. 182, 1883-1895.
24. Van Endert, P. M., Tampé, R., Meyer, T. H., Tisch, R., Bach, J.-F., McDevitt, H. O., 1994. A sequential model for peptide binding and transport by the transporters associated with antigen processing. Immunity 1, 491-500.