-
1
-
-
0033578095
-
Laboratory evolution of peroxide-mediated cytochrome P450-mediated cytochrome P450 hydroxylation
-
1. Joo, H., Lin, Z. & Arnold, F.H. (1999). Laboratory evolution of peroxide-mediated cytochrome P450-mediated cytochrome P450 hydroxylation. Nature 399, 670-673.
-
(1999)
Nature
, vol.399
, pp. 670-673
-
-
Joo, H.1
Lin, Z.2
Arnold, F.H.3
-
2
-
-
0033213940
-
A high-throughput digital imaging screen for the discovery and directed evolution of oxygenases
-
this issue
-
2. Joo, H., Arisawa, A., Lin, Z. & Arnold, F.H. (1999). A high-throughput digital imaging screen for the discovery and directed evolution of oxygenases. Chem. Biol. 6, this issue.
-
(1999)
Chem. Biol.
, vol.6
-
-
Joo, H.1
Arisawa, A.2
Lin, Z.3
Arnold, F.H.4
-
3
-
-
0025922972
-
P450BM-3 and other inducible bacterial P450 cytochromes - Biochemistry and regulation
-
3. Fulco, A.J. (1991). P450BM-3 and other inducible bacterial P450 cytochromes - biochemistry and regulation. Annu. Rev. Pharmacol. Toxicol. 31, 177-203.
-
(1991)
Annu. Rev. Pharmacol. Toxicol.
, vol.31
, pp. 177-203
-
-
Fulco, A.J.1
-
4
-
-
0026485793
-
High-level expression in Escherichia coli of enzymatically active fusion proteins containing the domains of mammalian cytochromes P450 and NADPH-P450 reductase flavoprotein
-
4. Fisher, C.W., Shet, M.S., Caudle, D.L., Martin-Wixtrom, C.A. & Estabrook, R.W. (1992). High-level expression in Escherichia coli of enzymatically active fusion proteins containing the domains of mammalian cytochromes P450 and NADPH-P450 reductase flavoprotein. Proc. Natl Acad. Sci. USA 89, 10817-10821.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 10817-10821
-
-
Fisher, C.W.1
Shet, M.S.2
Caudle, D.L.3
Martin-Wixtrom, C.A.4
Estabrook, R.W.5
-
5
-
-
0029809775
-
Putidaredoxin reductase-putidaredoxin-cytochrome P450cam triple fusion protein. Construction of a self-sufficient Escherichia coli catalytic system
-
5. Sibbesen, O., De Voss, J.J. & De Montellano, P.R.O. (1996). Putidaredoxin reductase-putidaredoxin-cytochrome P450cam triple fusion protein. Construction of a self-sufficient Escherichia coli catalytic system. J. Biol. Chem. 271, 22462-22469.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22462-22469
-
-
Sibbesen, O.1
De Voss, J.J.2
De Montellano, P.R.O.3
-
6
-
-
0023645035
-
High-resolution crystal structure of cytochrome P450cam
-
6. Poulos, T.L., Finzel, B.C. & Howard, A.J. (1987). High-resolution crystal structure of cytochrome P450cam. J. Mol. Biol. 195, 687-700.
-
(1987)
J. Mol. Biol.
, vol.195
, pp. 687-700
-
-
Poulos, T.L.1
Finzel, B.C.2
Howard, A.J.3
-
7
-
-
0032513137
-
The oxidation of naphthalene and pyrene by cytochrome P450cam
-
7. England, P.A., Harford-Cross, C.F., Stevenson, J.A., Rouch, D.A. & Wong, L.-L. (1998). The oxidation of naphthalene and pyrene by cytochrome P450cam. FEBS Lett. 424, 271-274.
-
(1998)
FEBS Lett.
, vol.424
, pp. 271-274
-
-
England, P.A.1
Harford-Cross, C.F.2
Stevenson, J.A.3
Rouch, D.A.4
Wong, L.-L.5
-
8
-
-
0000945213
-
Protein engineering of cytochrome P450cam
-
8. Wong, L.-L., Westlake, A.C.G. & Nickerson, D.P. (1997). Protein engineering of cytochrome P450cam. Struct. Bonding 88, 175-207.
-
(1997)
Struct. Bonding
, vol.88
, pp. 175-207
-
-
Wong, L.-L.1
Westlake, A.C.G.2
Nickerson, D.P.3
-
9
-
-
0030660230
-
Engineering the substrate specificity of Bacillus megaterium cytochrome P450 BM3: Hydroxylation of alkyl trimethylammonium compounds
-
9. Oliver, C.F., Modi, S., Primrose, W.U., Lian, L.-Y. & Roberts, G.C.K. (1997). Engineering the substrate specificity of Bacillus megaterium cytochrome P450 BM3: hydroxylation of alkyl trimethylammonium compounds. Biochem. J. 327, 537-544.
-
(1997)
Biochem. J.
, vol.327
, pp. 537-544
-
-
Oliver, C.F.1
Modi, S.2
Primrose, W.U.3
Lian, L.-Y.4
Roberts, G.C.K.5
-
10
-
-
0031033653
-
A single-residue mutation in cytochrome P450 changes the substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation
-
10. Oliver, C.F., Modi, S., Sutcliffe, M.J., Primrose, W.U., Lian, L.-Y. & Roberts, G.C.K. (1997). A single-residue mutation in cytochrome P450 changes the substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation. Biochemistry 36, 1567-1572.
-
(1997)
Biochemistry
, vol.36
, pp. 1567-1572
-
-
Oliver, C.F.1
Modi, S.2
Sutcliffe, M.J.3
Primrose, W.U.4
Lian, L.-Y.5
Roberts, G.C.K.6
-
11
-
-
0031021585
-
An active site substitution, F87V, converts cytochrome p450 BM-3 into a regio-and stereoselective (14S,15R)-arachidonic acid epoxygenase
-
11. Graham-Lorence, S., et al., & Capdevila, J.H. (1997). An active site substitution, F87V, converts cytochrome p450 BM-3 into a regio-and stereoselective (14S,15R)-arachidonic acid epoxygenase. J. Biol. Chem. 272, 1127-1135.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 1127-1135
-
-
Graham-Lorence, S.1
Capdevila, J.H.2
-
12
-
-
0000227103
-
Identification of three key residues in substrate recognition site 5 of human cytochrome P450 3A4 by cassette and site-directed mutagenesis
-
12. He, Y.A., He, Y.Q., Szklarz, G.D. & Halpert, J.R. (1997). Identification of three key residues in substrate recognition site 5 of human cytochrome P450 3A4 by cassette and site-directed mutagenesis. Biochemistry 36, 8831-8839.
-
(1997)
Biochemistry
, vol.36
, pp. 8831-8839
-
-
He, Y.A.1
He, Y.Q.2
Szklarz, G.D.3
Halpert, J.R.4
-
13
-
-
0032080291
-
Determinants of the substrate specificity of human cytochrome P450 CYP2D6: Design and construction of a mutant with testosterone hydroxylase activity
-
13. Smith, G., et al., & Wolf, C.R. (1998). Determinants of the substrate specificity of human cytochrome P450 CYP2D6: design and construction of a mutant with testosterone hydroxylase activity. Biochem. J. 331, 783-792.
-
(1998)
Biochem. J.
, vol.331
, pp. 783-792
-
-
Smith, G.1
Wolf, C.R.2
-
14
-
-
0001270261
-
Design by directed evolution
-
14. Arnold, F.H. (1998). Design by directed evolution. Accounts Chem. Res. 31, 125-131.
-
(1998)
Accounts Chem. Res.
, vol.31
, pp. 125-131
-
-
Arnold, F.H.1
-
15
-
-
0031442821
-
Creating novel enzymes by applied molecular evolution
-
15. Skandalis, A., Encell, L.P. & Loeb, L.A. (1997). Creating novel enzymes by applied molecular evolution. Chem. Biol. 4, 889-898.
-
(1997)
Chem. Biol.
, vol.4
, pp. 889-898
-
-
Skandalis, A.1
Encell, L.P.2
Loeb, L.A.3
-
16
-
-
0028050350
-
Rapid evolution of a protein in vitro by DNA shuffling
-
16. Stemmer, W.P.C. (1994). Rapid evolution of a protein in vitro by DNA shuffling. Nature 370, 389-391.
-
(1994)
Nature
, vol.370
, pp. 389-391
-
-
Stemmer, W.P.C.1
-
17
-
-
0030858562
-
Functional and non-functional mutations distinguished by random recombination of homologous genes
-
17. Zhao, H. & Arnold, F.H. (1997). Functional and non-functional mutations distinguished by random recombination of homologous genes. Proc. Natl Acad. Sci. USA 94, 7997-8000.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 7997-8000
-
-
Zhao, H.1
Arnold, F.H.2
-
18
-
-
0032518266
-
DNA shuffling of a family of genes from diverse species accelerates directed evolution
-
18. Crameri, A., Raillard, S.A., Bermudez, E. & Stemmer, W.P.C. (1998). DNA shuffling of a family of genes from diverse species accelerates directed evolution. Nature 391, 288-291.
-
(1998)
Nature
, vol.391
, pp. 288-291
-
-
Crameri, A.1
Raillard, S.A.2
Bermudez, E.3
Stemmer, W.P.C.4
-
19
-
-
0031854986
-
Man-made cell-like compartments for molecular evolution
-
19. Tawfik, D.S. & Griffiths, A. (1998). Man-made cell-like compartments for molecular evolution. Nat. Biotechnol. 16, 652-656.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 652-656
-
-
Tawfik, D.S.1
Griffiths, A.2
-
20
-
-
0029739962
-
Application of electrochemistry for P450-catalyzed reactions
-
20. Estabrook, R.W., Faulkner, K.M., Shet, M.S. & Fisher, C.W. (1996). Application of electrochemistry for P450-catalyzed reactions. Methods Enzymol. 272, 44-51.
-
(1996)
Methods Enzymol.
, vol.272
, pp. 44-51
-
-
Estabrook, R.W.1
Faulkner, K.M.2
Shet, M.S.3
Fisher, C.W.4
-
21
-
-
0028979829
-
Electrocatalytically driven omega-hydroxylation of fatty-acids using cytochrome P450 4A1
-
21. Faulkner, K.M., Shet, M.S., Fisher, C.W. & Estabrook, R.W. (1995). Electrocatalytically driven omega-hydroxylation of fatty-acids using cytochrome P450 4A1. Proc. Natl Acad. Sci. USA 92, 7705-7709.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 7705-7709
-
-
Faulkner, K.M.1
Shet, M.S.2
Fisher, C.W.3
Estabrook, R.W.4
-
22
-
-
0030474192
-
The use of electrochemistry for the synthesis of 17-alpha-hydroxyprogesterone by a fusion protein containing P450c17
-
22. Estabrook, R.W., Shet, M.S., Faulkner, K. & Fisher, C.W. (1996). The use of electrochemistry for the synthesis of 17-alpha-hydroxyprogesterone by a fusion protein containing P450c17. Endocrine Res. 22, 665-671.
-
(1996)
Endocrine Res.
, vol.22
, pp. 665-671
-
-
Estabrook, R.W.1
Shet, M.S.2
Faulkner, K.3
Fisher, C.W.4
-
23
-
-
0009734123
-
-
British patent application 9821932.2
-
23. Abbot, A., Ahmed, F., Cullis, P.M., Primrose, W.U. & Roberts, G.C.K. (1998). Cytochrome P450 electrochemical system; British patent application 9821932.2.
-
(1998)
Cytochrome P450 Electrochemical System
-
-
Abbot, A.1
Ahmed, F.2
Cullis, P.M.3
Primrose, W.U.4
Roberts, G.C.K.5
|