Fermentations with new recombinant organisms

Biotechnology Progress

Volumn 15, Issue 5, 1999, Pages 867-875

  Bothast, Rodney J ^a   Nichols, Nancy N ^a   Dien, Bruce S ^a  

^a NATIONAL CENTER FOR AGRICULTURAL UTILIZATION RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; BIOCATALYST; BIOFUEL; FERMENTATION; FUEL PRODUCTION; GENETIC ENGINEERING; RECOMBINANT DNA TECHNOLOGY;

BIOCATALYSTS; BIOMASS; BIOTECHNOLOGY; COST BENEFIT ANALYSIS; ENZYMES; ETHANOL; FEEDSTOCKS; GENETIC ENGINEERING; MICROORGANISMS; PRODUCTION ENGINEERING; SACCHARIFICATION; SUGARS;

GRAM NEGATIVE BACTERIA; SACCHAROMYCES CEREVISIAE; ZYMOMONAS MOBILIS;

FERMENTATION;

ESCHERICHIA COLI; SACCHAROMYCES CEREVISIAE; ZYMOMONAS MOBILIS;

EID: 0033199209     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp990087w     Document Type: Article

References (83)

1. Alterthum, F.; Ingram, L. O. Efficient ethanol production fromglucose, lactose, and xylose by recombinant Escherichia coli. Appl. Environ. Microbiol. 1989, 55, 1943-1948.
2. Amore, R.; Wilhelm, M.; Hollenberg, C. P. The fermentation of xylose-an analysis of the expression of Bacillus and Actino-planes xylose iaomerase genes in yeast. Appl. Microbiol. Biotechnol. 1989, 30, 351-357.
3. Asghari, A.; Bothast, R. J.; Doran, J. B.; Ingram, L. O. Ethanol production from hemicellulose hydrolyzates of agricultural residues using genetically engineered Escherichia coli strain KO11. J. Ind. Microbiol. 1996, 16, 42-47.
4. Baghaei-Yazdi, N.; Hartley, B. S.; Leak, D. J.; Amartey, S.; Leung, P. C. J.; Javed, M. Fuel alcohol and cellulose fibres from agricultural wastes. Proceedings of the 6th International Conference on Biotechnology in the Pulp and Paper Industry: Advances in Applied and Fundamental Research 1996, pp 281-286.
5. Barbosa, M. F. S.; Beck, M. J.; Fein, J. E.; Potts, D.; Ingram, L. O. Efficient fermentation of Pinus sp acid hydrolyzates by an ethanologenic strain of Escherichia coli. Appl. Environ. Microbiol. 1992, 58, 1382-1384.
6. Barbosa, M. de F. S.; Ingram, L. O. Expression of the Zymomonas mobilis alcohol dehydrogenase II (adhB) and pyruvate decarboxylase (pdc) genes in Bacillus. Curr. Microbiol. 1994, 28, 279-282.
7. Beall, D. S.; Ohta, K.; Ingram, L. O. Parametric studies of ethanol production from xylose and other sugars by recombinant Escherichia coli. Biotechnol. Bioeng. 1991, 38, 296-303.
8. Beall, D. S.; Ingram, L. O.; Ben-Bassat, A.; Doran, J. B.; Fowler, D. E.; Hall, R. G.; Wood, B. E. Conversion of hydrolyzates of corn cobs and hulls into ethanol by recombinant Escherichia coli B containing integrated genes for ethanol production. Biotechnol. Lett. 1992, 14, 857-862.
9. Bernard, N.; Ferain, T.; Garmyn, D.; Hols, P.; Delcour, J. Cloning of the D-lactate dehydrogenase gene from Lactobacillus delbrueckii subsp. bulgaricus by complementation in Escherichia coli. FEBS Lett. 1991, 290, 61-64.
10. Bothast, R. J.; Saha, B. C.; Flosenzier, A. V.; Ingram, L. O. Fermentation of L-arabinose, D-xylose and D-glucose by ethanologenic recombinant Klebsiella oxytoca strain P2. Biotechnol. Lett. 1994, 16, 401-406.
11. Burckhardt, G.; Ingram, L. O. Conversion of xylan to ethanol by ethanologenic strains of Escherichia coli and Klebsiella oxytoca. Appl. Environ. Microbiol. 1992, 58, 1128-1133.
12. Chou, Y.-C.; Zhang, M.; Mohagheghi, A.; Evans, K.; Finkelstein, M. Construction and evaluation of a xylose/arabinose fermenting strain of Zymomonas mobilis. 19th Symposium on Biotechnology Fuels; Chem. Abstr. 1997, Colorado Springs, May 4-8.
13. Clark, D. P. The fermentation pathways of Escherichia coli. FEMS Microbiol. Rev. 1989, 63, 223-234.
14. Deanda, K.; Zhang, M.; Eddy, C.; Picataggio, S. Development of an arabinose-fermenting Zymomonas mobilis strain by metabolic pathway engineering. Appl. Environ. Microbiol. 1996, 62, 4465-4470.
15. Delgenes, J. P.; Moletta, R.; Navarro, J. M. Fermentation ofD-xylose, D-glucose and L-arabinose mixture by Pichia stipitis Y7124: sugar tolerance. Appl. Microbiol. Biotechnol. 1988, 29, 155-161.
16. Deng, M.-D.; Coleman, J. R. Ethanol synthesis by genetic engineering in cyanobacteria. Appl. Environ. Microbiol. 1999, 65, 523-528.
17. Deverell, K. F. Ethanol production from wood hydrolyzates using Pachysolen tannophilus. Biotechnol. Lett. 1983, 5, 475-480.
18. de Vos, W. M.; Kleerebezem, M.; Kuipers, O. P. Expression systemsfor industrial gram-positive bacteria with low guanine and cytosine content. Curr. Opinion Biotechnol. 1997, 8, 547-553.
19. Dien, B. S.; Kurtzman, C. P.; Saha, B. C.; Bothast, R. J.Screening for L-arabinose fermenting yeasts. Appl. Biochem. Biotech. 1996, 57/58, 233-242.
20. Dien, B. S.; Hespell, R. B.; Ingram, L. O.; Bothast, R. J.Conversion of corn milling fibrous coproducts into ethanol by recombinant Escherichia coli strains KO11 and SL40. World J. Microbiol. Biotechnol. 1997, 13, 619-625.
21. Dien, B. S.; Hespell, R. B.; Wyckoff, H. A.; Bothast, R. J.Fermentation of hexose and pentose sugars using a novel ethanologenic Escherichia coli strain. Enzyme Microbial Technol. 1998, 23, 366-371.
22. Dien, B. S.; Iten, L. B.; Bothast, R. J. Conversion of corn fiber to ethanol by recombinant E. coli strain FBR3. J. Ind. Microbiol. Biotechnol. 1999, accepted for publication.
23. Doran, J. D.; Ingram, L. O. Fermentation of crystalline cellulose to ethanol by Klebsiella oxytoca containing chromosomally integrated Zymomonas mobilis genes. Biotechnol. Prog. 1993, 9, 533-538.
24. Doran, J. B.; Aldrich, H. H.; Ingram, L. O. Saccharification andfermentation of sugar cane bagasse by Klebsiella oxytoca P2 containing chromosomally integrated genes encoding the Zymomonas mobilis ethanol pathway. Biotechnol. Bioeng. 1994, 44, 240-247.
25. Dumsday, G. J.; Jones, K.; Stanley, G. A.; Pamment, N. B. Recombinant organisms for ethanol production from hemi-cellulosic hydrolyzates -a review of recent progress. Aust. Biotechnol. 1997a, 7, 285-295.
26. Dumsday, G. J.; Zhou, B.; Buhmann, S.; Stanley, G. A.; Pamment, N. B. Continuous ethanol production by Escherichia coli KO11 in continuous stirred tank and fluidized bed fermenters. Aust. Biotechnol. 1997b, 7, 300-303.
27. Du Preez, J. C.; Bosch, M.; Prior, B. A. The fermentation ofhexose and pentose sugars by Candida shehatae and Pichia stipitis. Appl. Microbiol. Biotechnol. 1986, 23, 228-233.
28. Ferain, T.; Hobbs, J. N., Jr.; Bernard, N.; Garmyn, D.; Hols, P.; Allen, N. E.; Delcour, J. Knockout of the two ldh genes has a major impact on peptidoglycan precursor synthesis in Lactobacillus plantarum. J. Bacteriol. 1996, 178, 5431-5437.
29. Ferain, T.; Schanck, A. N.; Hugenholtz, J.; Hols, P.; de Vos, W. M.; Delcour, J. Redistribution métabolique chez une souche de Lactobacillus plantarum déficiente en lactate déshydrogénase. Lait 1998, 78, 107-116.
30. Garmyn, D.; Ferain, T.; Bernard, N.; Hols, P.; Delcour, J. Cloning, nucleotide sequence, and transcriptional analysis of the Pediococcus acidilactici L-(+)-lactate dehydrogenase gène. Appl. Environ. Microbiol. 1995, 61, 266-272.
31. Gold, R. S.; Meagher, M. M.; Tong, S.; Hutkins, R. W.; Conway, T. Cloning and expression of the Zymomonas mobilis "production of ethanol" genes in Lactobacillus casei. Curr. Microbiol. 1996, 33, 256-260.
32. Gong, C.-S.; Chen, L.-F.; Flickinger, M. C.; Chiang, L.-C.; Tsao, G. T. Production of ethanol from D-xylose by using D-xylose isomerase and yeasts. Appl. Environ. Microbiol. 1981, 41, 430-436.
33. Grohmann, K.; Bothast, R. J. Saccharification of corn fiber bycombined treatment with dilute sulfuric acid and enzymes. Process Biochem. 1997, 32, 405-415.
34. Gulati, M.; Kohlmann, K.; Ladisch, M. R.; Hespell, R. B.; Bothast, R. J. Assessment of ethanol production options for corn products. Bioresour. Technol. 1997, 58, 253-264.
35. Hacking, A. J. Economic Aspects of Biotechnology, Cambridge University Press: Cambridge, U.K., 1986; pp 74-92.
36. Hahn-Hägerdal, B.; Jeppsson, H.; Olsson, L.; Mohagheghi, A. Aninterlaboratory comparison of the performance of ethanol-producing microorganisms in a xylose-rich acid hydrolyzate. Appl. Microbiol. Biotechnol. 1994, 41, 62-72.
37. Hespell, R. B.; Wyckoff, H. A.; Dien, B. S.; Bothast, R. J. Stabilization of pet operon plasmids and ethanol production in Escherichia coli strains lacking lactate dehydrogenase and pyruvate formate-lyase activities. Appl. Environ. Microbiol. 1996, 62, 4594-4597.
38. Hespell, R. B.; O'Bryan, P. J.; Moniruzzaman, M.; Bothast, R. J. Hydrolysis by commercial enzyme mixtures of AFEX-treated corn fiber and isolated xylans. Appl. Biochem. Biotechnol. 1997, 62, 87-97.
39. Ho, N. W. Y.; Tsao, G. T. Recombinant yeasts for effectivefermentation of glucose and xylose. PCT Patent No. W095/ 13362, 1995.
40. Ho, N. W. Y.; Chen, Z.; Brainard, A. P. Genetically engineered Saccharomyces yeast capable of effective cofermentation of glucose and xylose. Appl. Environ. Microbiol. 1998, 64, 1852-1859.
41. Ingram, L. O.; Conway, T.; Clark, D. P.; Sewell, G. W.; Preston, J. F. Genetic engineering of ethanol production in Escherichia coli. Appl. Environ. Microbiol. 1987, 53, 2420-2425.
42. Ingram, L. O.; Conway, T. Expression of different levels ofethanologenic enzymes from Zymomonas mobilis in recombinant strains of Escherichia coli. Appl. Environ. Microbiol. 1988, 54, 397-404.
43. Ingram, L. O.; Eddy, C. K.; Mackenzie, K. F.; Conway, T.; Alterthum, F. Genetics of Zymomonas mobilis and ethanol production. Dev. Ind. Microbiol. 1989, 30, 53-69.
44. Jeffries, T. W.; Sreenath, H. K. Fermentation of hemicellulose-sugars and sugar mixture by Candida shehatae. Biotechnol. Bioeng. 1988, 31, 502-506.
45. Jeffries, T. W.; Shi, N. Q.; Cho, J.; Lu, P.; Davis, B. Regulated expression of fermentative and respirative genes in Pichia stipitis for improved ethanol production. SIM Annu. Meet. Abstr. 1998, S-67.
46. Joachimsthal, E.; Haggett, K. D.; Rogers, P. L. Evaluation ofrecombinant strains of Zymomonas mobilis for ethanol production from glucose/xylose media. Appl. Biochem. Biotechnol. 1999, 77-79, 147-158.
47. Kurtzman, C. P.; Bothast, R. J.; VanCauwenberge, J. E. Conversionof D-xylose to ethanol by the yeast Pachysolen tannophilus. U.S. Patent 4359534, 1982.
48. Lawford, H. G.; Rousseau, J. D. Fuel ethanol from hardwood-hemicellulose hydrolyzate by genetically engineered Escherichia coli B carrying genes from Zymomonas mobilis. Biotechnol. Lett. 1991, 13, 191-196.
49. Lawford, H. G.; Rousseau, J. D. Loss of ethanologenicity in Escherichia coli B recombinants pLOI297 and KO11 during growth in the absence of antibiotics. Biotechnol. Lett. 1995, 17, 751-756.
50. Lawford, H. G.; Rousseau, J. D. Factors contributing to the loss of ethanologenicity of E. coli recombinants pLOI297 and K011. Appl. Biochem. Biotechnol. 1998, 57/58, 277-292.
51. Lawford, H. G.; Rousseau J. D.; McMillan, J. D. Optimization ofseed production for a simultaneous saccharification cofermentation biomass-to-ethanol process using recombinant Zymomonas. Appl. Biochem. Biotechnol. 1997, 63-5, 269-286.
52. Lawford, G. H.; Rousseau, J. D.; Mohagheghi, A.; McMillan, J. D. Continuous culture studies of xylose-fermenting Zymomonas mobilis. Appl. Biochem. Biotechnol. 1998, 70-72, 353-368.
53. Lawford, G. H.; Rousseau, J. D.; Mohagheghi, A.; McMillan, J. D.Fermentation performance characteristics of a prehydrolyzate-adapted xylose-fermenting recombinant Zymomonas in batch and continuous fermentations. Appl. Biochem. Biotechnol. 1999, 77-79, 191-204.
54. Lindsay, S. E.; Bothast, R. J.; Ingram, L. O. Improved strains ofrecombinant Escherichia coli for ethanol production from sugar mixtures. Appl. Microbiol. Biotechnol. 1995, 43, 70-75.
55. Mat-Jan, F.; Alam, K. Y.; Clark, D. P. Mutants of Escherichia coli deficient in the fermentative lactate dehydrogenase. J. Bacteriol. 1989, 171, 342-348.
56. McMillan, J. D.; Newman, M. M.; Templeton, D. W.; Mohagheghi, A. Simultaneous saccharification and cofermentation of dilute-acid pretreated yellow poplar hardwood to ethanol using xylose-fermenting Zymomonas mobilis. Appl. Biochem. Biotechnol. 1999, 77-79, 649-665.
57. Moes, C. J.; Pretorius, I. S.; van Zyl, W. H. Cloning andexpression of the Clostridium thermosulfurogenes D-xylose isomerase gene (xylA) in Saccharomyces cerevisiae. Biotechnol. Lett. 1996, 18, 269-274.
58. Moniruzzaman, M.; Dien, B. S.; Ferrer, B.; Hespell, R. B.; Dale, B. E.; Ingram, L. O.; Bothast, R. J. Ethanol production from AFEX pretreated corn fiber by recombinant bacteria. Biotechnol. Lett. 1996, 18, 985-990.
59. Moniruzzaman, M.; Dien, B. S.; Skory, C. D.; Chen, Z. D.; Hespell, R. B.; Ho, N. W. Y.; Dale, B. E.; Bothast, R. J. Fermentation of corn fibre sugars by an engineered xylose utilizing Saccharomyces yeast strain. World J. Microbiol. Biotechnol. 1997, 13, 341-346.
60. Neirinck, L.; Maleszka, R.; Schneider, H. Alcohol production fromsugar mixtures by Pachysolen tannophilus. Biotechnol. Bioeng. Symp. 1982, 12, 161-169.
61. Ohta, K.; Beall, D. S.; Mejia, J. P.; Shanmugam, K. T.; Ingram, L. O. Genetic improvement of Escherichia coli for ethanol production: chromosomal integration of Zymomonas mobilis genes encoding pyruvate decarboxylase and alcohol dehydrogenase II. Appl. Environ. Microbiol. 1991, 57, 893-900.
62. Ostendorp, R.; Liebl, W.; Schurig, H.; Jaenicke, R. The L-lactate dehydrogenase gene of the hyperthermophilic bacterium Thermotoga maritima cloned by complementation in Escherichia coli. Eur. J. Biochem. 1993, 216, 709-715.
63. Ranatunga, T. D.; Jervis, J.; Helm, R. F.; McMillan, J. D.; Hatzis, C. Identification of inhibitory components toxic towards Zymomonas mobilis CP4 (pZB5) xylose fermentation. Appl. Biochem. Biotechnol. 1997, 67, 185-198.
64. Renewable Fuels Association, Ethanol Report. Issue #85, Washington, DC, December 3, 1998.
65. Rogers, P. L.; Joachimsthal, E. L.; Haggett, K. D. Ethanol from lignocellulosics: potential for a Zymomonas-based process. Aust. Biotechnol. 1997, 7, 304-309.
66. San Martin, R.; Bushell, D.; Leak, D. J.; Hartley, B. S. Cultivation of an L-lactate dehydrogenase mutant of Bacillus stearothermophilus in continuous culture with cell recycle. Biotechnol. Bioeng. 1994, 44, 21-28.
67. Sarthy, A. V.; McConaughy, B. L.; Lobo, Z.; Sundstrom, J. A.; Furlong, C. E.; Hall, B. D. Expression of the Escherichia coli xylose isomerase gene in Saccharomyces cerevisiae. Appl. Environ. Microbiol. 1987, 53, 1996-2000.
68. Schneider, H.; Maleszka, R.; Neirinck, L.; Veliki, I. A.; Wang, P. Y.; Cjan, Y. K. Ethanol production from D-xylose and several other carbohydrates by Pachysolen tannophilus and other yeasts. Adv. Biochem. Eng./Biotechnol. 1983, 27, 57-71.
69. Sivers, M.; von Zacchi, G.; Olsson, L.; Hahn-Hägerdal, B. Costanalysis of ethanol production from willow using recombinant Escherichia coli. Biotechnol. Prog. 1994, 10, 555-560.
70. Slininger, P. J.; Bothast, R. J.; Okos, M. R; Ladisch, M. R. Comparative evaluation of ethanol production by xylose-fermenting yeasts presented high xylose concentrations. Biotechnol. Lett. 1985, 7, 431-436.
71. Slininger, P. J.; Bolen, P. L.; Kurtzman, C. P. Pachysolen tannophilus: properties and process considerations for ethanol production from D-xylose. Enzyme Microb. Technol. 1987, 9, 5-15.
72. Smiley, K. L.; Bolen, P. L. Demonstration of D-xylose reductase and D-xylitol dehydrogenase in Pachysolen tannophilus. Biotechnol. Lett. 1982, 4, 607-610.
73. Sonensheim, A. L.; Hoch, J. A.; Losick, R. Bacillus subtilis and other gram-positive bacteria. Biochemistry, Physiology and Molecular Biology; American Society for Microbiology: Washington, DC, 1993.
74. Stevis, P. E.; Ho, N. W. Y. Overproduction of D-xylose isomerase in Escherichia coli by cloning the D-xylose isomerase gene. Enzyme Microb. Technol. 1985, 7, 592-596.
75. Toon, S. T.; Philippidis, G. P.; Ho, N. W. Y.; Chen, Z.; Brainard, A.; Lumpkin, R. E.; Riley, C. J. Enhanced cofermentation of glucose and xylose by recombinant Saccharomyces yeast strains in batch and continuous operating modes. Appl. Biochem. Biotechnol. 1997, 63-65, 243-255.
76. U.S. Department of Energy, Biofuels, A Solution for Climate Change. DOE/GO-10098-580, November 1998.
77. Walfridsson, M.; Bao, X.; Anderlund, M.; Lilius, G.; Bulow, L.; Hahn-Hägerdal, B. Ethanolic fermentation of xylose with Saccharomyces cerevisiae harboring the Thermus thermophilus xylA gene, which expresses an active xylose (glucose) isomerase. Appl. Environ. Microbiol. 1996, 62, 4648-4651.
78. Wood, B. E.; Ingram, L. O. Ethanol production from cellobiose,-amorphous cellulose, and crystalline cellulose by recombinant Klebsiella oxytoca containing chromosomally integrated Zymomonas mobilis genes for ethanol production and plasmids expressing thermostable cellulase genes from Clostridium thermocellum. Appl. Environ. Microbiol. 1992, 58, 2103-2110.
79. Wyckoff, H. A.; Chow, J.; Whitehead, T. R; Cotta, M. A. Cloning, sequence, and expression of the L-(+) lactate dehydrogenase of Streptococcus bovis. Curr. Microbiol. 1997, 34, 367-373.
80. Wyman, C. E. Alternative fuels from biomass and their impact oncarbon dioxide accumulation. Appl. Biochem. Biotechnol. 1994, 45/46, 897-915.
81. Zhang, M.; Eddy, C.; Deanda, K.; Finkelstein, M.; Picataggio, S. Metabolic engineering of a pentose metabolism pathway in ethanologenic Zymomonas mobilis. Science 1995, 267, 240-243.
82. Zhang, M.; Chou, Y. C.; Lai, X. K.; Milstrey, S.; Danielson, N.; Mohagheghi, A.; Evans, K.; Finkelstein, M. Recent advances in metabolic engineering of Zymomonas mobilis for pentose utilization. SIM Annu. Meet. Abstr. 1998, S-65.
83. Zhang, M.; Chou, Y. C.; Lai, X. K.; Milstrey, S.; Danielson, N.; Evans, K.; Mohagheghi, A.; Finkelstein, M. Recent advances in the development of Zymomonas mobilis for pentose utilization. Abstracts of the 21st Symposium of Biotechnology Fuels and Chemistry; 1999, Poster 2-16.