Knockout of the two ldh genes has a major impact on peptidoglycan precursor synthesis in Lactobacillus plantarum

Journal of Bacteriology

Volumn 178, Issue 18, 1996, Pages 5431-5437

  Ferain, T ^a   Hobbs Jr , J N ^b   Richardson, J ^b   Bernard, N ^a   Garmyn, D ^a   Hols, P ^a   Allen, N E ^b   Delcour, J ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDOGLYCAN; URIDINE DIPHOSPHATE N ACETYLMURAMIC ACID;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL CELL WALL; BINDING AFFINITY; CROSS LINKING; ENZYME SPECIFICITY; LACTOBACILLUS PLANTARUM; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; STEM CELL; STEREOSPECIFICITY;

BACTERIA (MICROORGANISMS); LACTOBACILLUS PLANTARUM;

EID: 0029809746     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.178.18.5431-5437.1996     Document Type: Article

References (51)

1. Allen, N. E., J. N. Hobbs, and W. E. Alborn. 1987. Inhibition of peptidoglycan biosynthesis in gram-positive bacteria by LY146032. Antimicrob. Agents Chemother. 31:1093-1099.
2. Allen, N. E., J. N. Hobbs, J. M. Richardson, and R. M. Riggin. 1992. Biosynthesis of modified peptidoglycan precursors by vancomycin-resistant Enterococcus faecium. FEMS Microbiol. Lett. 98:109-116.
3. 2a. Arthur, M. Personal communication.
4. Arthur, M., and P. Courvalin. 1993. Genetics and mechanism of glycopeptide resistance in enterococci. Antimicrob. Agents Chemother. 37:1563-1571.
5. Arthur, M., C. Molinas, T. D. H. Bugg, G. D. Wright, C. T. Walsh, and P. Courvalin. 1992. Evidence for in vivo incorporation of D-lactate into peptidoglycan precursors of vancomyin-resistant enterococci. Antimicrob. Agents Chemother. 36:867-869.
6. Arthur, M., C. Molinas, F. Depardieu, and P. Courvalin. 1993. Characterization of Tn/546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. J. Bacteriol. 175:117-127.
7. Arthur, M., C. Molinas, S. Dutka-Malen, and P. Courvalin. 1991. Structural relationship between the vancomycin resistance protein VanH and 2-hydroxycarboxylic acid dehydrogenases. Gene 103:133-134.
8. Barna, J. C. J., and D. H. Williams. 1984. The structure and mode of action of glycopeptide antibiotics of the vancomycin group. Annu. Rev. Microbiol. 38:339-357.
9. Bernard, N., K. Johnsen, T. Ferain, D. Garmyn, P. Hols, and J. J. Holbrook. 1994. NAD' -dependent D-2-hydroxyisocaproate dehydrogenase of Lactobacillus delbrueckii subsp. bulgaricus. Gene cloning and enzyme characterization. Eur. J. Biochem. 224:439-446.
10. Billot-Klein, D., L. Gutmann, S. Sablé, E. Guittet, and J. van Htijenoort. 1994. Modification of peptidoglycan precursors is a common feature of the low-level vancornycin-resistant VANB-type enterococcus D366 and of the naturally glycopeptide-resistant species Lactobacillus casei, Pedivcoccus penlosaceus, Leuconostoc mesenteroides, and Enterococcus gallinarum. J. Bacteriol. 176:2398-2405.
11. Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
12. Bugg, T. D. H., S. Dutka-Malen, M. Arthur, P. Courvalin, and C. T. Walsh. 1991. Identification of vancomycin resistance protein Van A as a D-alanine: D-alanine ligase of altered substrate specificity. Biochemistry 30:2017-2021.
13. Bugg, T. D. H., G. D. Wright, S. Dutka-Malen, M. Arthur, P. Courvalin, and C. T. Walsh. 1991. Molecular basis for vancomycin resistance in Enterococcus faecium BM4I47: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA. Biochemistry 30:10408-10415.
14. Caspritz, G., and F. Radler. 1983. Malolactic enzyme of Lactobacillus plantarum. J. Biol. Chem. 258:4907-4910.
15. Chen, J.-D., and D. A. Morrison. 1988. Construction and properties of a new insertion vector, pJDC9, that is protected by transcriptional terminators and useful for cloning of DNA from Streptococcus pneumonia?. Gene 64:155-164.
16. Colman, G., and A, Efstratiou. 1987. Vancomycin-resistant leuconostocs, lactohacilli and now pediococci. J. Hosp, Infect. 10:1-3.
17. Dower, W. J., J. F. Miller, and C. W. Ragsdale. 1988. High efficiency transformation of E. coli by high voltage electroporation. Nucleic Acids Res. 16:6127.
18. Dutka-Malen, S., C. Molinas, M. Arthur, and P. Courvalin. 1990. The VANA glycopeptide resistance protein is related to D-alanyl-D-alaninc ligase cell wall biosynthesis enzymes. Mol. Gen. Genet. 224:364-372.
19. Dutka-Malen, S., C. Molinas, M. Arthur, and P. Courvalin. 1992. Sequence of the vanC gene of Enterococcus gallinarum BM4174 encoding a D-alanine: D-alanine ligase-related protein necessary for vancomycin resistance. Gene 112:53-58.
20. Elisha, B. G., and P. Courvalin. 1995. Analysis of genes encoding D-alanine: D-alanine ligase-related enzymes in Leuconostoc mesenteroides and Lactobacillus spp. Gene 152:79-83.
21. Facklam, K., D. Hollis, and M. D. Collins. 1989. Identification of grampositive coccal and coccobacillary vancomycin-resistant bacteria. J. Clin. Microbiol. 27:724-730.
22. Ferain, T., D. Garmyn, N. Bernard, P. Hols, and J. Delcour. 1994. Lactobacillus plantarum IdhL gene: overexpression and deletion. J. Bacteriol. 176:596-601.
23. Ferain, T., A. N. Schanck, and J. Delcour. Unpublished results.
24. Gibson, T. J. 1984. Ph.D. thesis. Cambridge University, Cambridge, United Kingdom.
25. Gorecki, M., A. Bar-Eli, Y. Burstein, A. Patchornik, and E. B. Chain. 1975. Purification of D-alanine carboxypeptidase from Escherichia coli B on a penicillin-Sepharose column. Biochem. J. 147:131-137.
26. Handwerger, S., M. J. Pucci, K. J. Volk, J. Liu, and M. S. Lee. 1992. The cytoplasmic peplidoglycan precursor of vancomycin-resistant Enterococcus faecalis terminates in lactate. J. Bacteriol. 174:5982-5984.
27. Handwerger, S., M. J. Pucci, K. J. Volk, J. Liu, and M. S. Lee. 1994. Vancomycin-resistant Leuconostoc mesenteroides and Lactobacillus casei synthesize cytoplasmic peptidoglycan precursors that terminate in lactate. J. Bacteriol. 176:260-264.
28. Hiyama, T., S. Fukui, and K. Kitahara. 1968. Purification and properties of lactate racemase from Lactobacillus sake. J. Biochem. 64:99-107.
29. Hummel, W, and M.-R. Kula. 1989. Dehydrogenases for the synthesis of chiral compounds. Eur. J. Biochem. 184:1-13.
30. Johnson, K., C. Duez, J.-M. Frère, and J.-M. Ghuysen. 1975. β-Lactamases (Actinomyces species). Methods Enzymol. 43:687-698.
31. Josson, K., T. Scheirlinck, F. Michiels, C. Plalteeuw, P. Stanssens, H. Joos, P. Dhaese, M. Zabeau, and J. Mahillon. 1989. Characterization of a grampositive broad-host-range plasmid isolated from Lactobacillus hilgardii. Plasmid 21:9-20.
32. Kaneuchi, C., M. Seki, and K. Komagata. 1988. Production of succinic acid from citric acid and related acids by Lactobacillus strains. Appl. Environ. Microbiol. 54:3053-3056.
33. Kok, J., J. M. B. M. van der Vossen, and G. Venema. 1984. Construction of plasmid cloning vectors for lactic streptococci which also replicate in Bacillus subtilis and Escherichia coli. Appl. Environ. Microbiol. 48:726-731.
34. Leclereq, R., S. Dutka-Malen, J. Duval, and P. Courvalin. 1992. Vancomycin resistance gene vanC is specific to Enterococcus gallinarum. Antimicrob. Agents Chemother. 36:2005-2008.
35. Lerch, H.-P., H. Blöcker, H. Kallwas, J. Hoppe, H. Tsai, and J. Collins. 1989. Cloning, sequencing and expression in Escherichia coli of the D-2-hydroxyisocaproate dehydrogenase gene of Lactobacillus casei. Gene 78:47-57.
36. Lerch, H.-P., R. Frank, and J. Collins. 1989. Cloning, sequencing and expression of the L-2-hydroxyisocaproate dehydrogenase-encoding gene of Lactobacillus confusus in Escherichia coli. Gene 83:263-270.
37. Messer, J., and P. E. Reynolds. 1992. Modified peptidoglycan precursors produced by glycopeptide-resistant enterococci. FEMS Microbiol. Lett. 94:195-200.
38. Mizushima, S., and K. Kitahara. 1962. Purification and properties of lactic dehydrogenase of Lactobacillus casei. J. Gen. Appl. Microbiol. 8:130-141.
39. Nyugen-Disteche, M., M. Leyh-Bouille, S. Pirlot, J.-M. Frère, and J.-M. Ghuysen. 1986. Streptomyces K15 DD-peptidase-catalyzed reactions with ester and amide carbonyl donors. Biochem. J. 235:167-176.
40. Orberg, P. K., and W. E. Sandine. 1984. Common occurrence of plasmid DNA and vancomycin resistance in Leuconostoc spp. Appl. Environ. Microbiol. 48:1129-1133.
41. Posno, M., R. J. Leer, N. van Luijk, M. J. F. van Giezen, P. T. H. M. Heuvelmans, B. C. Lokman, and P. H. Pouwels. 1991. Incompatibility of Lactobacillus vectors with replicons derived from small cryptic Lactobacillus plasmids and segregational instability of the introduced vectors. Appl. Environ. Microbiol. 57:1822-1828.
42. Reynolds, P. E. 1989. Structure, biochemistry and mechanism of action of glycopeptide antibiotics. Eur. J. Clin. Microbiol. Infect. Dis. 8:943-950.
43. Reynolds, P. E., F. Depardieu, S. Dutka-Malen, M. Arthur, and P. Courralin. 1994. Glycopeptide resistance mediated by enterococcal transposon Tn 1546 requires production of VanX for hydrolysis of D-alanyl-D-alanine. Mol. Microbiol. 13:1065-1070.
44. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
45. Schleifer, K. H., and O. Kandler. 1972. Peptidoglycan types of bacterial cell walls and their taxonomic implications. Bacteriol. Rev. 36:407-477.
46. Stetter, K. O., and O. Kandler. 1973. Untersuchungen zur Entstehung von DL-Milchsäure bei Lactobacillen und Charakterisierung einer Milchsäureracemase bei einigen Arten der Untergattung Streptobacterium. Arch. Mikrobiol. 94:221-247.
47. Swenson, J. M., R. R. Facklam, and C. Thornsberry. 1990. Antimicrobial susceptibility of vancomycin-resistant Leuconostoc, Pediococcus, and Lactobacillus species. Antimicroh. Agents Chemother. 34:543-549.
48. Taguchi, H., and T. Ohta. 1991. D-Lactate dehydrogenase is a member of the D-isomer-specific 2-hydroxyacid dehydrogenase family. J. Biol. Chem. 266:12588-12594.
49. Van Heijenoort, J. 1994. Biosynthesis of the bacterial peptidoglycan unit, p. 39-55. In J.-M. Ghuysen and R. Hackenbeck (ed.), Bacterial cell wall. Elsevier Science B. V., Amsterdam.
50. Vescovo, M., L. Morelli, and V. Bottazi. 1982. Drug resistance plasmids in Lactobacillus acidophilus and Lactobacillus reuteri. Appl. Environ. Microbiol. 43:50-56.
51. Zanoni, P., J. A. E. Farrow, B. A. Phillips, and M. D. Collins. 1987. Lacto- bacillus pentosus (Fred, Peterson, and Anderson) sp. nov., nom. rev. Int. J. Syst. Bacteriol. 37:339-341.