Expression systems for industrial Gram-positive bacteria with low guanine and cytosine content

Current Opinion in Biotechnology

Volumn 8, Issue 5, 1997, Pages 547-553

  De Vos, Willem M ^a,b   Kleerebezem, Michiel ^a   Kuipers, Oscar P ^a  

^a NIZO FOOD RESEARCH   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; GUANINE;

BACILLUS; BIOTECHNOLOGY; CATABOLITE REPRESSION; CLOSTRIDIUM; GENE EXPRESSION; GENE INDUCTION; GRAM POSITIVE BACTERIUM; LACTOBACILLUS; LACTOCOCCUS; NONHUMAN; PLASMID; PRIORITY JOURNAL; RECOMBINANT DNA TECHNOLOGY; REVIEW; STAPHYLOCOCCUS; STREPTOCOCCUS; TRANSPOSON;

BACTERIA (MICROORGANISMS); CLOSTRIDIUM; LACTOBACILLUS; LACTOCOCCUS; POSIBACTERIA; STAPHYLOCOCCUS; STREPTOCOCCUS;

EID: 0030660435     PISSN: 09581669     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0958-1669(97)80027-4     Document Type: Article

References (70)

1. Ferrari E, Jarnagin AS, Schmidt BF: Commercial production of extracellular enzymes. In Bacillus Subtilis and Other Gram-Positive Bacteria. Biochemistry, Physiology and Molecular Biology Edited by Sonensheim AL, Hoch JA, Losick R. Washington: American Society for Microbiology; 1993:917-937.
2. Woese CR: Bacterial evolution. Microbiol Rev 1987, 51:221-271
3. Binnie C, Cossar JD, Stewart DIH: Heterologous biopharmaceutical protein expresion in Streptomyces. Trends Biotechnol 1997, 15:315-320.
4. Janniere L, Gruss A, Ehrlich SD: Plasmids. In Bacillus Subtilis and Other Gram-Positive Bacteria. Biochemistry, Physiology and Molecular Biology. Edited by Sonensheim AL, Hoch JA, Losick R. Washington: American Society for Microbiology; 1993:625-645.
5. De Vos WM, Simons G: Gene cloning and expression systems in lactococci. In Genetics and Biotechnology of Lactic Acid Bacteria. Edited by Gasson MJ, de Vos WM. Oxford: Chapman and Hall; 1994:52-105.
6. Renault P: Genetic engineering strategies. In Lactic Acid Bacteria: Current Advances in Metabolism, Genetics and Applications. Edited by Bozoglu TF, Ray B. Berlin: Springer-Verlag; 1996:1-37. [NATO Symposium Series.]
7. O'Sullivan DJ, Klaenhammer: High- and low-copy-number Lactococcus shuttle cloning vectors with features for clone screening. Gene 1993, 137:227-231.
8. Renault P, Corthier G, Goupil N, Delorme C, Ehrlich SD: Plasmid vectors for gram-positive bacteria switching from high to low copy number. Gene 1996, 183:175-182. Illustrates the rational design of useful tools based on insight in the copy number control system of the broad host-range plasmid pAMβ1. Described vectors will be useful for many low guanine and cytosine Gram-positive bacteria.
9. Pouwels PH, Leer RJ: Genetics of lactobacilli: plasmids and gene expression. Antonie van Leeuwenhoek 1993, 64:85-107.
10. Maguin E, Duwat P, Hege T, Ehrlich SD, Gruss A: New thermosensitive plasmid for gram-positive bacteria. J Bacteriol 1992, 174:5633-5638.
11. Maguin E, Prevost H, Ehrlich SD, Gruss A: Efficient insertional mutagenesis on lactococci and other Gram-positive bacteria. J Bacteriol 1996, 178:931-935. Delivery system for a broad host-range transposon eliminating the need for efficient transformation. Useful tool that will allow genetic analysis of wide range of low guanine and cytosine Gram-positive bacteria.
12. Gasson MJ, Fitzgerald GF: Gene transfer systems and transposition. In Genetics and Biotechnology of Lactic Acid Bacteria. Edited by Gasson MJ, de Vos WM. Oxford: Chapman and Hall; 1994:1-51.
13. Youngman P: Transposons and their applications. In Bacillus Subtilis and Other Gram-positive Bacteria. Biochemistry, Physiology and Molecular Biology. Edited by Sonensheim AL, Hoch JA, Losick R. Washington: American Society for Microbiology; 1993:585-596.
14. Israelson H, Madsen SM, Vrang A, Hansen EB, Johansen E: Cloning and partial characterization of regulated promoters from Lactococcus lactis Tn917-lacZ integrants with the new promoter probe vector, pAK80. Appl Environ Microbiol 1995, 61:2540-2547.
15. Scott JR: Conjugative transposons. In Bacillus Subtilis and Other Gram-Positive Bacteria. Biochemistry, Physiology and Molecular Biology. Edited by Sonensheim AL, Hoch JA, Losick R. Washington: American Society for Microbiology; 1993:597-613.
16. Moran CP: RNA polymerase and transcription factors. In Bacillus Subtilis and Other Gram-Positive Bacteria. Biochemistry, Physiology and Molecular Biology. Edited by Sonensheim AL, Hoch JA, Losick R. Washington: American Society for Microbiology; 1993:653-668.
17. Voskuil MI, Voepel K, Chambliss GH: The -16 region, a vital sequence for the utilization of a promoter in Bacillus subtilis and Escherichia coli. Mol Microbiol 1995, 17:271-279.
18. Helmann JD: Compilation and analysis of Bacillus subtilis sigma A-dependent promoter sequences: evidence for extended contact between RNA polymerase and upstream promoter DNA. Nucleic Acids Res 1995, 23:2351-2360.
19. Platteeuw C, Simons G, de Vos WM: Use of the Escherichia coli β-glucuronidase (gusA) gene as a reported gene for analyzing promoters in lactic acid bacteria. Appl Environ Microbiol 1995, 60:587-593.
20. Vellanoweth RL: Translation and its regulation. In Bacillus Subtilis and Other Gram-Positive Bacteria. Biochemistry, Physiology and Molecular Biology. Edited by Sonensheim AL, Hoch JA, Losick R. Washington: American Society for Microbiology; 1993:699-711.
21. Rabinowitz JC, Roberts M: Translational barriers limiting expression of E. coli genes in Bacillus subtilis and other Gram-positive organisms. In Antibiotic Resistance Genes: Ecologyy, Transfer, and Expression. Edited by Levy SB, Novick RP. Cold Spring Harbor: Cold Spring Harbor Laboratories; 1986:297-312.
22. Chambliss GH: Carbon source mediated catabolite repression. In Bacillus Subtilis and Other Gram-Positive Bacteria. Biochemistry, Physiology and Molecular Biology. Edited by Sonensheim AL, Hoch JA, Losick R. Washington: American Society for Microbiology; 1993:213-219.
23. Hueck C, Hillen W: Catabolite repression in Bacillus subtilis: a global regulatory mechanism for the Gram-positive bacteria? Mol Microbiol 1995, 15:395-401.
24. Deutscher J, Kuster E, Bergstedt U, Charrier V, Hillen W: Protein-kinase dependent HPr/CcpA interaction links glycolytic activity to carbon catabolite repression in Gram-positive bacteria. Mol Microbiol 1995, 15:1049-1053.
25. Kuster E, Luesink EJ, de Vos WM, Hillen W: Immunological cross-reactivity to catabolite control protein CcpA from B. megaterium is found in many Gram-positive bacteria. FEMS Microbiol Lett 1996, 139:109-115.
26. Luesink EJ, Vaughan EE, Kuipers OP, de Vos WM: Catabolite repression in lactic acid bacteria. Le Lait 1997, in press.
27. Egeter O, Brückner R: Catabolite repression mediated by the catabolite control protein CcpA in Staphylococcus xylosus. Mol Microbiol 1997, 21:739-749.
28. Jacob S, Allmansberger R, Gartner D, Hillen W: Catabolite repression of the operon for xylose utilization from Bacillus subtilis W23 is mediated at the level of transcription and depends on a cis site in the xylA reading frame. Mol Gen Gener 1991, 229:189-196.
29. Sizemore C, Wieland B, Gotz F, Hillen W: Regulation of the Staphylococcus xylosus xylose utilization genes at the molecular level. J Bacteriol 1991, 174:3042-3048.
30. Lokman BC, Heerikshuizen M, van den Broek A, Borsboom Y, Chaillou S, Postma PW, Pouwels PH: Regulation of the Lactobacillus pentosus xylAB operon. J Bacteriol 1997, 179:in press.
31. Salmond GPC, Bycroft BW, Stewart GSAB, Williams P: The bacterial enigma: cracking the code of cell-cell communication. Mol Microbiol 1995, 16:615-624.
32. Kleerebezem M, Quadri LEN, Kuipers OP, de Vos WM: Quorum sensing by peptide pheromones and two-component signal transduction systems in Gram-positive bacteria. Mol Microbiol 1997, 24:895-905. Overview of the peptide pheromone-induced quorum-sensing modules that are operating in low guanine and cytosine Gram-positive bacteria and function via a two-component regulatory system.
33. Magnusson R, Solomon J, Grossman AD: Biochemical and genetic characterization of a competence pheromone from Bacillus subtilis. Cell 1994, 77:207-216.
34. Grossman DA: Genetic networks controlling initiation of sporulation and development of genetic competence in Bacillus subtilis. Ann Rev Genet 1995, 29:477-508.
35. Hȧvarstein LS, Coomaraswamy G, Morrison DA: An unmodified heptadecapeptide pheromone induces competence for genetic transformation in Streptococcus pneumoniae. Proc Natl Acad Sci USA 1995, 92:11140-11144.
36. Pestova EV, Håvarstein LS, Morrison DA: Regulation of competence for genetic transformation in Streptococcus pneumoniae by an auto-induced peptide pheromone and a two-component regulatory system. Mol Microbiol 1996, 21:853-862.
37. Ji GY, Beavis RC, Novick RP: Cell density control of staphylococcal virulence mediated by an octapeptide pheromone. Proc Natl Acad Sci USA 1995, 92:12055-12059.
38. Guangyong Ji, Beavis R, Novick RP: Bacterial interference caused by autoinducing peptide variants. Science 1997, 276:2027-2030.
39. Diep DB, Havarstein LS, Nes IF: A bacteriocin-like peptide induces bacteriocin synthesis in Lactobacillus plantarum C11. Mol Microbiol 1995, 18:631-639.
40. Eijsink VGH, Brurberg MB, Middelhoven PH, Nes IF: Induction of bacteriocin production in Lactobacillus sake by a secreted peptide. J Bacteriol 1996, 178:2232-2237.
41. Kuipers OP, Beerthuyzen MM, de Ruyter PGGA, Luesink EJ, de Vos WM: Autoregulation of nisin biosynthesis in Lactococcus lactis by signal transduction. J Biol Chem 1995, 270:27299-27304.
42. De Vos WM, Kuipers OP, van der Meer JR, Siezen RJ: Maturation pathway of nisin and other lantibiotics: post-translationally modified antimicrobial peptides exported by Gram-positive bacteria. Mol Microbiol 1995, 17:427-437.
43. Kuipers OP, de Ruyter PGGA, Kleerebezem M, de Vos WM: Controlled overproduction of proteins by lactic acid bacteria. Trends Biotechnol 1997, 15:135-140. This report discusses the different systems used for enzyme overproduction in lactic acid bacteria and describes the nisin-inducible gene expression system resulting in controlled hyperproduction of intracellular enzymes in L. lactis.
44. Yansura DG, Henner DJ: Use of the Escherichia coli lac repressor and operator to control gene expression in Bacillus subtilis. Proc Nat Acad Sci USA 1984, 81:439-443.
45. Conrad B, Savchenko RS, Breves R, Hofeweister J: A T7 promoter-specific, inducible protein expression system for Bacillus subtilis. Mol Gen Genet 1996, 250:230-236.
46. Kim L, Mogk A, Schumann W: A xylose-inducible Bacillus subtilis integration vector and its application. Gene 1996, 181:71-76.
47. Ebisu S, Takagi H, Kadowaki K, Yamagata H, Udaka S: The efficient production of human epidermal growth factor by Bacillis brevis. Ann N Y Acad Sci 1996, 782:115-122. Describes the capacity of B. brevis for the extracellular production of proteins and illustrates the potential of an alternative Bacillus host.
48. Nagao M, Inoue K, Moon SK, Masuda S, Takagi H, Udaka S, Sasaki R: Secretory production of erythropoeietin and the extracellulair domain of the erythropoeietin receptor by Bacillus brevis: affinity purification and characterization. Biosci Biotechnol Biochem 1997, 61:670-674.
49. Nagaham M, Michiue K, Sakurai J: Production and purification of Clostridium perfringens alpha-toxin using a protein-hyperproducing strain, Bacillus brevis 47. FEMS Microbiol Lett 1996, 145:239-243.
50. Young M, Cole ST: Clostridia. In Bacillus Subtilis and Other Gram-Positive Bacteria. Biochemistry, Physiology and Molecular Biology. Edited by Sonensheim AL, Hoch JA, Losick R. Washington: American Society for Microbiology; 1993:35-53.
51. Rood JI, McClane BA, Songer JG, Titball RW: The Clostridia: Molecular Biology and Pathogenesis. New York: Academic Press; 1997.
52. Wong J, Bennet GN: Recombination-induced variants of Clostridium acetobutylicum ATCC 824 with increased solvent production. Curr Microbiol 1996, 32:349-356.
53. Fox ME, Lemmon MJ, Mauchline ML, Davis TO, Giacca AJ, Minton NP, Brown JM: Anaerobic bacteria as a deliviry system for cancer therapy: in vitro activation of 5-fluorocytosine by genetically engineered clostridia. Gene Ther 1996, 3:173-178. The authors describes an original approach that may allow for the therapeutical use of Clostridia, due to their potential to reach and kill cancer cells.
54. Peschel A, Ottenwalder B, Gotz F: Inducible production and cellular location of the epidermin biosynthetic enzyme EpiB and improved staphylcococal expression system. FEMS Microbiol Lett 1996, 137:279-284.
55. Weiland K-P, Weiland B, Gotz F: A promoter-screening plasmid and xylose-inducible, glucose-repressible expression vectors for Staphylococcus carnosus. Gene 1996, 158:91-96.
56. Samuelsson P, Hannson M, Ahlborg N, Androni C, Gotz F, Bach T, Nguyen TN, Binz H, Uhlen W, Stahl S: Cell surface display of recombinant protein on Staphylococcus carnosus. J Bacteriol 1995, 177:1470-1476.
57. Gunneriusson E, Samelson P, Uhlen M, Nygren PA, Stahl S: Surface display of a functional single chain Fv antibody on staphylococci. J Bacteriol 1996, 178:1341-1346.
58. Mollet B, Knol J, Poolman B, Marciset O, Delley M: Directed genomic integration, gene replacement and integrative gene expression in Streptococcus thermophilus. J Bacteriol 1993, 175:4315-4324.
59. Oggioni MR, Pozzi G: A host-vector system for heterologous gene expression in Streptococcus gordonii. Gene 1996, 169:85-90.
60. Klaenhammer TR: Genetics of intestinal lactobacilli. Int Dairy J 1995, 5:39-86.
61. Kok J: Inducible gene expression and environmentally regulated genes in lactic acid bacteria. Antoine van Leeuwenhoek 1996, 70:129-145.
62. Hols P, Ferain T, Garmyn D, Bernard N, Delcour J: Use of homologous expression-secretion signals and vector-free stable chromosomal integration in engineering of Lactobacillus plantarum for α-amylase and levanase expression. Appl Environ Microbiol 1994, 60:1401-1413.
63. Savijoki K, Kahala M, Palva A: High level heterologous protein production in Lactococcus and Lactobacillus using a new secretion system based on the Lactobacillus brevis S-layer signals. Gene 1997, 186:255-262.
64. Waterfield NR, LePage RWF, Wilson PW, Wells JM: The Isolation of Lactococcal promoters and their sse in investigating bacterial luciferase synthesis in Lactococcus lactis. Gene 1995, 165:9-15.
65. Wellls JM, Wilson PW, Norton PM, Gasson MJ, Le Page RWP: Lactococcus lactis: high level expression of tetanus toxin fragment C and protection against lethal challenge. Mol Microbiol 1995, 8:1155-1162.
66. Steidler L, Wells JM, Raemakers A, Vanderkerckhove J, Fiers W, Remaut E: Secretion of biologically active murine interleukin-2 by Lactococcus lactis subsp. lactis. Appl Environ Microbiol 1995, 61:1627-1629.
67. Robinson K, Chamberlain LM, Schofield KM, Wells JM, LePage RWF: Oral vaccination of mice against tetanus with recombinant Lactococcus lactis. Nat Biotechnol 1997, 15:653-657.
68. Nauta A, van Sinderen D, Karsens H, Smit E, Venema G, Kok J: Inducible gene expression mediated by a represser-operator system isolated from Lactococcus lactis bacteriophage-R1T. Mol Microbiol 1996, 19:1331-1341.
69. O'Sullivan DJ, Walker SA, West SG, Klaenhammer TR: Development of an expression strategy using a lytic phage to trigger explosive plasmid amplification and gene expression. Bio-Technology 1996, 14:82-87. The authors describe an elegant system describing coupling of overproduction and lysis of the expression host L lactis. Induction is not triggered by the addition of a chemical but of a bacteriophage particle.
70. De Ruyter PGGA, Kuipers OP, de Vos WM: Controlled gene expression systems for Lactococcus lactis with the food-grade inducer nisin. Appl Environ Microbiol 1996, 62:3662-3667.