메뉴 건너뛰기




Volumn 59, Issue 15, 1999, Pages 3634-3640

High frequency and heterogeneous distribution of p53 mutations in aflatoxin B1-induced mouse lung tumors

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN B1; AMINO ACID; DNA; PROTEIN P53;

EID: 0033179379     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (43)

References (59)
  • 2
    • 0025968509 scopus 로고
    • Lung tumors in strain a mice as a bioassay for carcinogenicity of environmental chemicals
    • Stoner, G. D. Lung tumors in strain A mice as a bioassay for carcinogenicity of environmental chemicals. Exp. Lung Res., 17: 405-423, 1991.
    • (1991) Exp. Lung Res. , vol.17 , pp. 405-423
    • Stoner, G.D.1
  • 4
    • 0013887920 scopus 로고
    • Oral, subcutaneous and intratracheal administration of carcinogenic lactones and related substances: The intratracheal administration of cigarette tar in the rat
    • Dickens, F., Jones, H. E. H., and Waynforth, H. B. Oral, subcutaneous and intratracheal administration of carcinogenic lactones and related substances: the intratracheal administration of cigarette tar in the rat. Br. J. Cancer, 20: 134-144, 1966.
    • (1966) Br. J. Cancer , vol.20 , pp. 134-144
    • Dickens, F.1    Jones, H.E.H.2    Waynforth, H.B.3
  • 5
  • 6
    • 0025040133 scopus 로고
    • 1-DNA adducts in cultured mammalian tracheal epithelium
    • 1-DNA adducts in cultured mammalian tracheal epithelium. Cancer Res., 50: 4918-4922, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 4918-4922
    • Ball, R.W.1    Wilson, D.W.2    Coulombe, R.A.3
  • 8
    • 0026337295 scopus 로고
    • Tumor suppressor genes
    • Washington DC
    • Weinberg, R. A. Tumor suppressor genes. Science (Washington DC), 254: 1138-1146, 1991.
    • (1991) Science , vol.254 , pp. 1138-1146
    • Weinberg, R.A.1
  • 10
    • 0026579237 scopus 로고
    • TP53 tumor suppressor gene: A model for investigating human mutagenesis
    • Caron, D. F., and Soussi, T. TP53 tumor suppressor gene: a model for investigating human mutagenesis. Genes Chromosomes Cancer, 4: 1-15, 1992.
    • (1992) Genes Chromosomes Cancer , vol.4 , pp. 1-15
    • Caron, D.F.1    Soussi, T.2
  • 14
  • 15
    • 0027109075 scopus 로고
    • Cancer. p53, guardian of the genome
    • Lane, D. P. Cancer. p53, guardian of the genome. Nature (Lond. ), 358: 15-16, 1992.
    • (1992) Nature (Lond. ) , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 17
    • 0028343058 scopus 로고
    • Geographic variation of p53 mutational profile in nonmalignant human liver
    • Washington DC
    • Aguilar, F., Harris, C. C., Sun, T., Hollstein, M., and Cerutti, P. Geographic variation of p53 mutational profile in nonmalignant human liver. Science (Washington DC), 264: 1317-1319, 1994.
    • (1994) Science , vol.264 , pp. 1317-1319
    • Aguilar, F.1    Harris, C.C.2    Sun, T.3    Hollstein, M.4    Cerutti, P.5
  • 18
    • 0025732215 scopus 로고
    • Mutational hotspot in the p53 gene in human hepatocellular carcinomas
    • Hsu, I. C., Metcalf, R. A., Sun, T., Welsh, J. A., Wang, N. J., and Harris, C. C. Mutational hotspot in the p53 gene in human hepatocellular carcinomas. Nature (Lond.), 350: 427-428, 1991.
    • (1991) Nature (Lond.) , vol.350 , pp. 427-428
    • Hsu, I.C.1    Metcalf, R.A.2    Sun, T.3    Welsh, J.A.4    Wang, N.J.5    Harris, C.C.6
  • 19
    • 0025828517 scopus 로고
    • Selective G to T mutations of p53 gene in hepatocellular carcinoma from Southern Africa
    • Bressac, B., Kew, M., Wands, J., and Ozturk, M. Selective G to T mutations of p53 gene in hepatocellular carcinoma from Southern Africa. Nature (Lond.), 350: 429-431, 1991.
    • (1991) Nature (Lond.) , vol.350 , pp. 429-431
    • Bressac, B.1    Kew, M.2    Wands, J.3    Ozturk, M.4
  • 20
    • 0025748539 scopus 로고
    • p53 mutation in hepatocellular carcinoma after aflatoxin exposure
    • Ozturk, M. p53 mutation in hepatocellular carcinoma after aflatoxin exposure. Lancet, 338: 1356-1359, 1991.
    • (1991) Lancet , vol.338 , pp. 1356-1359
    • Ozturk, M.1
  • 21
    • 0026518760 scopus 로고
    • p53 mutations cluster at codon 249 in hepatitis B virus-positive hepatocellular carcinomas from China
    • Scorsone, K. A., Zhou, Y-Z., Butel, J. S., and Slagle, B. L. p53 mutations cluster at codon 249 in hepatitis B virus-positive hepatocellular carcinomas from China. Cancer Res., 52: 1635-1638, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 1635-1638
    • Scorsone, K.A.1    Zhou, Y.-Z.2    Butel, J.S.3    Slagle, B.L.4
  • 22
    • 0029008198 scopus 로고
    • Characterization of a murine p53ser246 mutant equivalent to the human p53ser249 associated with hepatocellular carcinoma and aflatoxin exposure
    • Ghebranious, N., Knoll, B. J., Wu, H., Lozano, G., and Sell, S. Characterization of a murine p53ser246 mutant equivalent to the human p53ser249 associated with hepatocellular carcinoma and aflatoxin exposure. Mol. Carcinogen., 13: 104-111, 1995.
    • (1995) Mol. Carcinogen. , vol.13 , pp. 104-111
    • Ghebranious, N.1    Knoll, B.J.2    Wu, H.3    Lozano, G.4    Sell, S.5
  • 24
    • 0026530243 scopus 로고
    • Murine p53 intron sequences 5-8 and their use in polymerase chain reaction/ direct sequencing analysis of p53 mutations in CD-1 mouse liver and lung tumors
    • Goodrow, T. L., Storer, R. D., Leander, K. R., Prahalada, S. R., van Zwieten, M. J., and Bradley, M. O. Murine p53 intron sequences 5-8 and their use in polymerase chain reaction/ direct sequencing analysis of p53 mutations in CD-1 mouse liver and lung tumors. Mol. Carcinogen., 5: 9-15, 1992.
    • (1992) Mol. Carcinogen. , vol.5 , pp. 9-15
    • Goodrow, T.L.1    Storer, R.D.2    Leander, K.R.3    Prahalada, S.R.4    Van Zwieten, M.J.5    Bradley, M.O.6
  • 25
    • 0027292743 scopus 로고
    • Dose-dependent ras mutation spectra in N-nitrosodiethylamine induced mouse liver tumors and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced mouse lung tumors
    • Lond.
    • Chen, B., Liu, L., Castonguay, A., Maronpot, R. R., Anderson, M. W., and You, M. Dose-dependent ras mutation spectra in N-nitrosodiethylamine induced mouse liver tumors and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced mouse lung tumors. Carcinogenesis (Lond.), 14: 1603-1608, 1993.
    • (1993) Carcinogenesis , vol.14 , pp. 1603-1608
    • Chen, B.1    Liu, L.2    Castonguay, A.3    Maronpot, R.R.4    Anderson, M.W.5    You, M.6
  • 27
    • 0028245344 scopus 로고
    • Relationships of DNA adduct formation, K-ras activating mutations and tumorigenic activities of 6-nitrochrysene and its metabolites in the lungs of CD-1 mice
    • Lond.
    • Li, E. E., Heflich, R. H., Bucci, T. J., Manjanatha, M. G., Blaydes, B. S., and Delclos, K. B. Relationships of DNA adduct formation, K-ras activating mutations and tumorigenic activities of 6-nitrochrysene and its metabolites in the lungs of CD-1 mice. Carcinogenesis (Lond.), 15: 1377-1385, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 1377-1385
    • Li, E.E.1    Heflich, R.H.2    Bucci, T.J.3    Manjanatha, M.G.4    Blaydes, B.S.5    Delclos, K.B.6
  • 29
    • 0030453289 scopus 로고    scopus 로고
    • Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice
    • Horio, Y., Chen, A., Rice, P., Roth, J. A., Malkinson, A. M., and Schrump, D. S. Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice. Mol. Carcinogen., 17: 217-223, 1996.
    • (1996) Mol. Carcinogen. , vol.17 , pp. 217-223
    • Horio, Y.1    Chen, A.2    Rice, P.3    Roth, J.A.4    Malkinson, A.M.5    Schrump, D.S.6
  • 33
    • 0032547380 scopus 로고    scopus 로고
    • Progress in understanding the molecular pathogenesis of human lung cancer
    • Sekido, Y., Fong, K. M., and Minna, J. D. Progress in understanding the molecular pathogenesis of human lung cancer. Biochim. Biophys. Acta, 1378: F21-F59, 1998.
    • (1998) Biochim. Biophys. Acta , vol.1378
    • Sekido, Y.1    Fong, K.M.2    Minna, J.D.3
  • 34
    • 0032530215 scopus 로고    scopus 로고
    • Molecular epidemiology of human cancer: Contribution of mutation spectra studies of tumor suppressor genes
    • Hussain, S. P., and Harris, C. C. Molecular epidemiology of human cancer: contribution of mutation spectra studies of tumor suppressor genes. Cancer Res., 58: 4023-4037, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 4023-4037
    • Hussain, S.P.1    Harris, C.C.2
  • 35
    • 0025618980 scopus 로고
    • Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: A comparison of the "hot spot" mutant phenotypes
    • Hinds, P. W., Finlay, C. A., Quartin, R. S., Baker, S. J., Fearon, E. R., Vogelstein, B., and Levine, A. J. Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes. Cell Growth Differ., 1: 571-580, 1990.
    • (1990) Cell Growth Differ. , vol.1 , pp. 571-580
    • Hinds, P.W.1    Finlay, C.A.2    Quartin, R.S.3    Baker, S.J.4    Fearon, E.R.5    Vogelstein, B.6    Levine, A.J.7
  • 36
    • 0028361705 scopus 로고
    • c-K-ras and p53 mutations occur very early in adenocarcinoma of the lung
    • Li, Z. H., Zheng, J., Weiss, L. M., and Shibata, D. c-K-ras and p53 mutations occur very early in adenocarcinoma of the lung. Am. J. Pathol., 144: 303-309, 1994.
    • (1994) Am. J. Pathol. , vol.144 , pp. 303-309
    • Li, Z.H.1    Zheng, J.2    Weiss, L.M.3    Shibata, D.4
  • 37
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Haupt, Y., Maya, R., Kazaz, A., and Oren, M. Mdm2 promotes the rapid degradation of p53. Nature (Lond.), 387: 296-299, 1997.
    • (1997) Nature (Lond.) , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 39
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine, A. J. p53, the cellular gatekeeper for growth and division. Cell, 88: 323-331, 1997.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 40
    • 0029806936 scopus 로고    scopus 로고
    • Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53
    • Washington DC
    • Denissenko, M. F., Pao, A., Tang, M., and Pfeifer, G. P. Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53. Science (Washington DC), 274: 430-432, 1996.
    • (1996) Science , vol.274 , pp. 430-432
    • Denissenko, M.F.1    Pao, A.2    Tang, M.3    Pfeifer, G.P.4
  • 41
    • 0029857892 scopus 로고    scopus 로고
    • DNA sequence analysis of exons 2 through 11 and immunohistochemical staining are required to detect all known p53 alterations in human malignancies
    • Casey, G., Lopez, M. E., Ramos, J. C., Plummer, S. J., Arboleda, M. J., Shaughnessy, M., Karlan, B., and Slamon, D. J. DNA sequence analysis of exons 2 through 11 and immunohistochemical staining are required to detect all known p53 alterations in human malignancies. Oncogene, 13: 1971-1981, 1996.
    • (1996) Oncogene , vol.13 , pp. 1971-1981
    • Casey, G.1    Lopez, M.E.2    Ramos, J.C.3    Plummer, S.J.4    Arboleda, M.J.5    Shaughnessy, M.6    Karlan, B.7    Slamon, D.J.8
  • 42
    • 0029919109 scopus 로고    scopus 로고
    • Hereditary cancer: Two hits revisited
    • Knudson, A. G. Hereditary cancer: two hits revisited. J. Cancer Res. Clin. Oncol., 122: 135-140, 1996.
    • (1996) J. Cancer Res. Clin. Oncol. , vol.122 , pp. 135-140
    • Knudson, A.G.1
  • 43
    • 0029827384 scopus 로고    scopus 로고
    • A comparative study of detection of p53 mutations in human breast cancer by flow cytometry, single-strand conformation polymorphism and genomic sequencing
    • Chakravarty, G., Redkar, A., and Mittra, I. A comparative study of detection of p53 mutations in human breast cancer by flow cytometry, single-strand conformation polymorphism and genomic sequencing. Br. J. Cancer, 74: 1181-1187, 1996.
    • (1996) Br. J. Cancer , vol.74 , pp. 1181-1187
    • Chakravarty, G.1    Redkar, A.2    Mittra, I.3
  • 44
    • 0029081501 scopus 로고
    • Simultaneous use of the PCR-SSCP method and immunohistochemistry for increasing the detection efficacy of p53 abnormalities in human lung cancer
    • Fujino, M., Dosaka-Akita, H., Kato, M., Kinoshita, I., Akie, K., and Kawakami, Y. Simultaneous use of the PCR-SSCP method and immunohistochemistry for increasing the detection efficacy of p53 abnormalities in human lung cancer. Am. J. Clin. Pathol., 104: 319-324, 1995.
    • (1995) Am. J. Clin. Pathol. , vol.104 , pp. 319-324
    • Fujino, M.1    Dosaka-Akita, H.2    Kato, M.3    Kinoshita, I.4    Akie, K.5    Kawakami, Y.6
  • 45
    • 0032530259 scopus 로고    scopus 로고
    • Inhibition of lung carcinogenesis by black tea in Fischer rats treated with a tobacco-specific carcinogen: Caffeine as an important constituent
    • Chung, F-L., Wang, M., Rivenson, A., Iatropoulos, M. J., Reinhardt, J. C., Pittman, B., Ho, C-T., and Amin, S. G. Inhibition of lung carcinogenesis by black tea in Fischer rats treated with a tobacco-specific carcinogen: caffeine as an important constituent. Cancer Res., 58: 4096-4101, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 4096-4101
    • Chung, F.-L.1    Wang, M.2    Rivenson, A.3    Iatropoulos, M.J.4    Reinhardt, J.C.5    Pittman, B.6    Ho, C.-T.7    Amin, S.G.8
  • 47
    • 0032549711 scopus 로고    scopus 로고
    • ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
    • Zhang, Y., Xiong, Y., and Yarbrough, W. G. ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell, 92: 725-734, 1998.
    • (1998) Cell , vol.92 , pp. 725-734
    • Zhang, Y.1    Xiong, Y.2    Yarbrough, W.G.3
  • 51
    • 0031914318 scopus 로고    scopus 로고
    • Hepatitis B injury, male gender, aflaloxin, and p53 expression each contribute to hepatocarcinogenesis in transgenic mice
    • Ghebranious, N., and Sell, S. Hepatitis B injury, male gender, aflaloxin, and p53 expression each contribute to hepatocarcinogenesis in transgenic mice. Hepatology, 27: 383-391, 1998.
    • (1998) Hepatology , vol.27 , pp. 383-391
    • Ghebranious, N.1    Sell, S.2
  • 52
    • 0027344549 scopus 로고
    • 1-induced rat hepatic hyperplastic nodules do not exhibit a site-specific mutation within the p53 gene
    • 1-induced rat hepatic hyperplastic nodules do not exhibit a site-specific mutation within the p53 gene. Cancer Res., 53: 9-11, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 9-11
    • Hulla, J.E.1    Chen, Z.Y.2    Eaton, D.L.3
  • 55
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt, M. S., Bennett, W. P., Hollstein, M., and Harris, C. C. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res., 54: 4855-4878, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 56
    • 0029397307 scopus 로고
    • The p53 gene and its role in human brain tumors
    • Bogler, O., Huang, H. J., Kleihues, P., and Cavenee, W. K. The p53 gene and its role in human brain tumors. Glia, 15: 308-327, 1995.
    • (1995) Glia , vol.15 , pp. 308-327
    • Bogler, O.1    Huang, H.J.2    Kleihues, P.3    Cavenee, W.K.4
  • 57
    • 0027184495 scopus 로고
    • Does a genotoxic carcinogen contribute to human breast cancer? The value of mutational spectra in unravelling the aetiology of cancer
    • Biggs, P. J., Warren, W., Venitt, S., and Stratton, M. R. Does a genotoxic carcinogen contribute to human breast cancer? The value of mutational spectra in unravelling the aetiology of cancer. Mutagenesis, 8: 275-283, 1993.
    • (1993) Mutagenesis , vol.8 , pp. 275-283
    • Biggs, P.J.1    Warren, W.2    Venitt, S.3    Stratton, M.R.4
  • 59
    • 0031965960 scopus 로고    scopus 로고
    • Predominant p53 G→A transition mutation and enhanced cell proliferation in uterine sarcomas of CBA mice treated with 1,2-dimethyl-hydrazine
    • Trukhanova, L. S., Hong, H. H., Sills, R. C., Bowser, A. D., Gaul, B., Boorman, G. A., Turusov, V. S., Devereux, T. R., and Dixon, D. Predominant p53 G→A transition mutation and enhanced cell proliferation in uterine sarcomas of CBA mice treated with 1,2-dimethyl-hydrazine. Toxicol. Pathol., 26: 367-374, 1998.
    • (1998) Toxicol. Pathol. , vol.26 , pp. 367-374
    • Trukhanova, L.S.1    Hong, H.H.2    Sills, R.C.3    Bowser, A.D.4    Gaul, B.5    Boorman, G.A.6    Turusov, V.S.7    Devereux, T.R.8    Dixon, D.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.