Predominant p53 G→A Transition Mutation and Enhanced Cell Proliferation in Uterine Sarcomas of CBA Mice Treated with 1,2-Dimethylhydrazine

Toxicologic Pathology

Volumn 26, Issue 3, 1998, Pages 367-374

  Trukhanova, Lyuba S ^a   Hong, Hue Hua L ^a   Sills, Robert C ^a   Bowser, Alicia D ^a   Gaul, Beth ^a   Boorman, Gary A ^b   Turusov, Vladimir S ^b   Devereux, Theodora R ^c   Dixon, Darlene ^c  

^a EXPERIMENTAL PATHOLOGY LABORATORIES INC   (United States)

^b INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

desmin; estrogen receptor; malignant fibrous histiocytoma; ras proto oncogene; stromal sarcoma; Tumor suppressor gene; undifferentiated sarcoma

Indexed keywords

1,2 DIMETHYLHYDRAZINE; 6 O METHYLGUANINE; ADENINE; ALKYLATING AGENT; CYCLINE; DESMIN; DNA; ESTROGEN RECEPTOR; GUANINE; PROTEIN P53; RAS PROTEIN; THYMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASE MISPAIRING; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DNA SEQUENCE; FEMALE; IMMUNOHISTOCHEMISTRY; MALIGNANT FIBROUS HISTIOCYTOMA; MISSENSE MUTATION; MOUSE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; ONCOGENE RAS; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE; UTERUS SARCOMA;

1,2-DIMETHYLHYDRAZINE; ANIMALS; CELL DIVISION; DESMIN; FEMALE; GENES, P53; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED CBA; POINT MUTATION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROLIFERATING CELL NUCLEAR ANTIGEN; RECEPTORS, ESTROGEN; SARCOMA, EXPERIMENTAL; TUMOR SUPPRESSOR PROTEIN P53; UTERINE NEOPLASMS;

ANIMALIA; RODENTIA;

EID: 0031965960     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/019262339802600310     Document Type: Article

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