메뉴 건너뛰기




Volumn 17, Issue 5, 1996, Pages 1007-1012

An aflatoxin-associated mutational hotspot at codon 249 in the p53 tumor suppressor gene occurs in hepatocellular carcinomas from Mexico

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN B1; DNA; HEPATITIS ANTIBODY; PROTEIN P53; RABBIT ANTISERUM; SERUM ALBUMIN;

EID: 15844415447     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.5.1007     Document Type: Article
Times cited : (101)

References (52)
  • 2
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt,M.S., Bennett,W.P., Hollstein,M. and Harris,C.C. (1994) Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res., 55, 4855-4878.
    • (1994) Cancer Res. , vol.55 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 3
    • 0027109075 scopus 로고
    • p53, guardian of the genome
    • Lane,D.P. (1992) p53, guardian of the genome. Nature, 358, 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 4
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach,E., Resnitzky,D., Lotem,J., Sachs,L., Kimchi,A. and Oren,M. (1991) Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature, 352, 345-347.
    • (1991) Nature , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6
  • 5
    • 0025787250 scopus 로고
    • Primary hepatocellular carcinoma
    • Wands,J.R. and Blum,H.E. (1991) Primary hepatocellular carcinoma. New Engl. J. Med., 325, 729-731.
    • (1991) New Engl. J. Med. , vol.325 , pp. 729-731
    • Wands, J.R.1    Blum, H.E.2
  • 9
    • 0027337609 scopus 로고
    • Aflatoxin B1 induces the transversion of G to T in codon 249 of the p53 tumor suppressor gene in human hepatocytes
    • Aguilar,F., Hussain,S.P and Cerutti,P. (1993) Aflatoxin B1 induces the transversion of G to T in codon 249 of the p53 tumor suppressor gene in human hepatocytes. Proc. Natl Acad. Sci. USA. 90, S586-S590.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90
    • Aguilar, F.1    Hussain, S.P.A.2    Cerutti, P.3
  • 10
    • 0027344549 scopus 로고
    • Aflatoxin B1-induced rat hepatic hyperplastic nodules do not exhibit a site-specific mutation within the p53 gene
    • Hulla,J.E., Chen,Z.Y. and Eaton,D.L. (1993) Aflatoxin B1-induced rat hepatic hyperplastic nodules do not exhibit a site-specific mutation within the p53 gene. Cancer Res., 53, 9-11.
    • (1993) Cancer Res. , vol.53 , pp. 9-11
    • Hulla, J.E.1    Chen, Z.Y.2    Eaton, D.L.3
  • 11
    • 0026449670 scopus 로고
    • Alterations in the p53 tumor suppressor gene in rat liver tumors induced by aflatoxin B1
    • Lilleberg,S.L., Cabonce,M.A., Raju,N.R., Wagner,L.M. and Kier,L.D. (1992) Alterations in the p53 tumor suppressor gene in rat liver tumors induced by aflatoxin B1. Prog. Clin. Biol. Res., 376, 203-222.
    • (1992) Prog. Clin. Biol. Res. , vol.376 , pp. 203-222
    • Lilleberg, S.L.1    Cabonce, M.A.2    Raju, N.R.3    Wagner, L.M.4    Kier, L.D.5
  • 12
    • 0026532048 scopus 로고
    • Low frequency of p53 gene mutation in tumors induced by aflatoxin B1 in nonhuman primates
    • Fujimoto,Y., Hampton,L.L., Luo,L.D., Wirth,P.J. and Thorgeirsson,S.S. (1992) Low frequency of p53 gene mutation in tumors induced by aflatoxin B1 in nonhuman primates. Cancer Res., 52, 1044-1046.
    • (1992) Cancer Res. , vol.52 , pp. 1044-1046
    • Fujimoto, Y.1    Hampton, L.L.2    Luo, L.D.3    Wirth, P.J.4    Thorgeirsson, S.S.5
  • 13
    • 0025732215 scopus 로고
    • Mutational hotspot in the p53 gene in human hepatocellular carcinomas
    • Hsu,I.C., Metcalf,R.A., Sun,T. Welsh,J.A., Wang,N.J. and Harris,C.C. (1991) Mutational hotspot in the p53 gene in human hepatocellular carcinomas. Nature, 350, 427-428.
    • (1991) Nature , vol.350 , pp. 427-428
    • Hsu, I.C.1    Metcalf, R.A.2    Sun, T.3    Welsh, J.A.4    Wang, N.J.5    Harris, C.C.6
  • 14
    • 0025828517 scopus 로고
    • Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa
    • Bressac,B., Kew,M., Wands,J. and Ozturk,M. (1991) Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa. Nature. 350, 429-431.
    • (1991) Nature , vol.350 , pp. 429-431
    • Bressac, B.1    Kew, M.2    Wands, J.3    Ozturk, M.4
  • 15
    • 0025748539 scopus 로고
    • p53 mutation in hepatocellular carcinoma after aflatoxin exposure
    • Ozturk,M. and Collaborators,A. (1991) p53 mutation in hepatocellular carcinoma after aflatoxin exposure. Lancet. 338, 1356-1359.
    • (1991) Lancet , vol.338 , pp. 1356-1359
    • Ozturk, M.1    Collaborators, A.2
  • 16
    • 0028343058 scopus 로고
    • Geographic variation of p53 mutational profile in nonmalignant human liver
    • Aguilar,F., Harris,C.C., Sun,T., Hollstein,M. and Cerutti,P. (1994) Geographic variation of p53 mutational profile in nonmalignant human liver. Science, 264, 1317-1319.
    • (1994) Science , vol.264 , pp. 1317-1319
    • Aguilar, F.1    Harris, C.C.2    Sun, T.3    Hollstein, M.4    Cerutti, P.5
  • 17
    • 0027983669 scopus 로고
    • Crystal structure of a p53 tumor suppressor-DNA complex: Understanding tumorigenic mutations
    • Cho,Y., Gorina,S., Jeffrey,P. and Pavletich,N.P. (1994) Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science, 364, 346-355.
    • (1994) Science , vol.364 , pp. 346-355
    • Cho, Y.1    Gorina, S.2    Jeffrey, P.3    Pavletich, N.P.4
  • 18
    • 0028334311 scopus 로고
    • Solving the viral-chemical puzzle of human liver carcinogenesis
    • Harris,C.C. (1994) Solving the viral-chemical puzzle of human liver carcinogenesis. Cancer Epidemiol. Biomarkers Prev., 3, 1-2.
    • (1994) Cancer Epidemiol. Biomarkers Prev. , vol.3 , pp. 1-2
    • Harris, C.C.1
  • 19
    • 0026767416 scopus 로고
    • Cellular and molecular mechanisms of hepatocarcinogenesis
    • Rogler,C.E. and Chisari,F.V. (1992) Cellular and molecular mechanisms of hepatocarcinogenesis. Semin. Liver Dis., 12, 265-278.
    • (1992) Semin. Liver Dis. , vol.12 , pp. 265-278
    • Rogler, C.E.1    Chisari, F.V.2
  • 20
    • 0027157304 scopus 로고
    • Hepatitis B x antigen and p53 are associated in vitro and in liver tissues from patients with primary hepatocellular carcinoma
    • Feitelson,M.A., Zhu,M., Duan,L.-X. and London,W.T. (1993) Hepatitis B x antigen and p53 are associated in vitro and in liver tissues from patients with primary hepatocellular carcinoma. Oncogene. 8, 1109-1117.
    • (1993) Oncogene , vol.8 , pp. 1109-1117
    • Feitelson, M.A.1    Zhu, M.2    Duan, L.-X.3    London, W.T.4
  • 21
    • 0001655748 scopus 로고
    • Hepatitis B virus X protein inhibits p53 sequence-specific DNA bindins, transcriptional activity, and association with transcription factor ERCC3
    • Wang,X.W., Forrester,K., Yeh,H., Feitelson,M.A., Gu,J.-R. and Harris,C.C. (1994) Hepatitis B virus X protein inhibits p53 sequence-specific DNA bindins, transcriptional activity, and association with transcription factor ERCC3. Proc. Natl Acad. Sci. USA, 91, 2230-2234.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 2230-2234
    • Wang, X.W.1    Forrester, K.2    Yeh, H.3    Feitelson, M.A.4    Gu, J.-R.5    Harris, C.C.6
  • 23
    • 0028135497 scopus 로고
    • Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras. Raf. MAP kinase signaling cascade
    • Benn,J. and Schneider, R.J. (1994) Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras. Raf. MAP kinase signaling cascade. Proc. Natl Acad. Sci. USA, 91, 10350-10354.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 10350-10354
    • Benn, J.1    Schneider, R.J.2
  • 24
    • 0027437858 scopus 로고
    • p53 protein accumulates frequently in early bronchial neoplasia
    • Bennett,W.P. et al. (1993) p53 protein accumulates frequently in early bronchial neoplasia. Cancer Res., 53, 4817-4822.
    • (1993) Cancer Res. , vol.53 , pp. 4817-4822
    • Bennett, W.P.1
  • 26
    • 0024589807 scopus 로고
    • The murine p53 protein blocks replication of SV40 DNA in vitro by inhibiting the initiation functions of SV40 large T antigen
    • Wang,E.H., Friedman,P.N. and Prives,C. (1989) The murine p53 protein blocks replication of SV40 DNA in vitro by inhibiting the initiation functions of SV40 large T antigen. Cell, 57, 379-392.
    • (1989) Cell , vol.57 , pp. 379-392
    • Wang, E.H.1    Friedman, P.N.2    Prives, C.3
  • 27
    • 0026569616 scopus 로고
    • Expression of human p53 in bacteria: Application to the analysis of p53 expression in human tumours
    • Midgley,C.A., Fisher,C.J., Bartek,J., Vojtesek,B., Lane,D.P. and Barnes,D.M. (1992) Expression of human p53 in bacteria: application to the analysis of p53 expression in human tumours. J. Cell Sci., 101, 183-189.
    • (1992) J. Cell Sci. , vol.101 , pp. 183-189
    • Midgley, C.A.1    Fisher, C.J.2    Bartek, J.3    Vojtesek, B.4    Lane, D.P.5    Barnes, D.M.6
  • 28
    • 0021037449 scopus 로고
    • Bromocresol purple and the measurement of albumin. Falsely high plasma albumin concentrations eliminated by increased reagent ionic strength
    • Hill,P.G. and Wells,T.N. (1983) Bromocresol purple and the measurement of albumin. Falsely high plasma albumin concentrations eliminated by increased reagent ionic strength. Ann. Clin. Biochem., 20, 264-270.
    • (1983) Ann. Clin. Biochem. , vol.20 , pp. 264-270
    • Hill, P.G.1    Wells, T.N.2
  • 29
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford,M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem,. 72, 248-254.
    • (1976) Anal. Biochem,. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 32
    • 33846322173 scopus 로고    scopus 로고
    • Variability of molecular biomarker measurements from nonlinear calibration curves
    • in press
    • Gange,S.J., Munoz,A., Wang,J. and Groopman,J.D. (1996) Variability of molecular biomarker measurements from nonlinear calibration curves. Cancer Epidemiol. Biomarkers Prev., 4. in press.
    • (1996) Cancer Epidemiol. Biomarkers Prev. , vol.4
    • Gange, S.J.1    Munoz, A.2    Wang, J.3    Groopman, J.D.4
  • 33
    • 0025006110 scopus 로고
    • The aflatoxin-lysine adduct quantified by high-performance liquid chromatography from human serum albumin samples
    • Sabbioni,G., Ambs,S., Wogan,G.N. and Groopman,J.D. (1990) The aflatoxin-lysine adduct quantified by high-performance liquid chromatography from human serum albumin samples. Carcinogenesis. 11. 2063-2066.
    • (1990) Carcinogenesis , vol.11 , pp. 2063-2066
    • Sabbioni, G.1    Ambs, S.2    Wogan, G.N.3    Groopman, J.D.4
  • 34
    • 0023197905 scopus 로고
    • Isolation and characterization of the major serum albumin adduct formed by aflatoxin B1 in vivo in rats
    • Sabbioni,G., Skipper,P.L., Buchi,G. and Tannenbaum,S.R. (1987) Isolation and characterization of the major serum albumin adduct formed by aflatoxin B1 in vivo in rats. Carcinogenesis, 8, 819-824.
    • (1987) Carcinogenesis , vol.8 , pp. 819-824
    • Sabbioni, G.1    Skipper, P.L.2    Buchi, G.3    Tannenbaum, S.R.4
  • 38
    • 0027325389 scopus 로고
    • High prevalence of mutations at codon 249 of the p53 gene in hepatocellular carcinomas from Senegal
    • Coursaget,P., Depril,N., Chabaud,M., Nandi,R., Mayelo,V., LeCann,P. and Yvonnet.B. (1993) High prevalence of mutations at codon 249 of the p53 gene in hepatocellular carcinomas from Senegal. Br. J. Cancer, 67, 1395-1397.
    • (1993) Br. J. Cancer , vol.67 , pp. 1395-1397
    • Coursaget, P.1    Depril, N.2    Chabaud, M.3    Nandi, R.4    Mayelo, V.5    LeCann, P.6    Yvonnet, B.7
  • 39
    • 0026452174 scopus 로고
    • Mutation of p53 gene in hepatocellular carcinoma in Taiwan
    • Sheu,J.C. et al. (1992) Mutation of p53 gene in hepatocellular carcinoma in Taiwan. Cancer Res., 52, 6098-6100.
    • (1992) Cancer Res. , vol.52 , pp. 6098-6100
    • Sheu, J.C.1
  • 41
    • 0027510125 scopus 로고
    • Infrequent mutation of p53 gene in hepatitis B virus positive primary hepatocellular carcinomas
    • Hosono,S., Chou,M.J., Lee,C.S. and Shih,C. (1993) Infrequent mutation of p53 gene in hepatitis B virus positive primary hepatocellular carcinomas. Oncogene, 8, 491-496.
    • (1993) Oncogene , vol.8 , pp. 491-496
    • Hosono, S.1    Chou, M.J.2    Lee, C.S.3    Shih, C.4
  • 42
    • 0027182097 scopus 로고
    • Analysis of the p53 gene in European hepatocellular carcinomas and hepatoblastomas
    • Debuire,B., Paterlini,P., Pontisso,P., Basso,G. and May,E. (1993) Analysis of the p53 gene in European hepatocellular carcinomas and hepatoblastomas. Oncogene, 8, 2303-2306.
    • (1993) Oncogene , vol.8 , pp. 2303-2306
    • Debuire, B.1    Paterlini, P.2    Pontisso, P.3    Basso, G.4    May, E.5
  • 44
    • 0025933070 scopus 로고
    • Glutathione S-transferase mu in human lymphocyte and liver: Role in modulating formation of carcinogen-derived DNA adducts
    • Liu,Y.H., Taylor,J., Linko,P., Lucier,G.W. and Thompson,C.L. (1991) Glutathione S-transferase mu in human lymphocyte and liver: role in modulating formation of carcinogen-derived DNA adducts. Carcinogenesis, 12, 2269-2275.
    • (1991) Carcinogenesis , vol.12 , pp. 2269-2275
    • Liu, Y.H.1    Taylor, J.2    Linko, P.3    Lucier, G.W.4    Thompson, C.L.5
  • 45
    • 0028957898 scopus 로고
    • Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1
    • McGlynn,K.A. et al. (1995) Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1. Proc. Natl Acad. Sci. USA, 92, 2384-2387.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 2384-2387
    • McGlynn, K.A.1
  • 46
    • 0027285918 scopus 로고
    • Molecular dosimetry of aflatoxin exposure: Contribution to understanding the multifactorial etiopathogenesis of primary hepatocellular carcinoma with particular reference to hepatitis B virus
    • Wild,C.P., Jansen,L.A., Cova,L. and Montesano,R. (1993) Molecular dosimetry of aflatoxin exposure: contribution to understanding the multifactorial etiopathogenesis of primary hepatocellular carcinoma with particular reference to hepatitis B virus. Environ. Hlth Perspect., 99, 115-122.
    • (1993) Environ. Hlth Perspect. , vol.99 , pp. 115-122
    • Wild, C.P.1    Jansen, L.A.2    Cova, L.3    Montesano, R.4
  • 47
    • 33646234399 scopus 로고    scopus 로고
    • Temporal patterns of aflatoxin-albumin adducts in hepatitis B surface antigen positive and negative residents of Daxin. Qidong County, P.R.C.
    • in press
    • Wang,J.-S. et al. (1996) Temporal patterns of aflatoxin-albumin adducts in hepatitis B surface antigen positive and negative residents of Daxin. Qidong County, P.R.C. Cancer Epidemiol. Biomarkers Prev., 5, in press.
    • (1996) Cancer Epidemiol. Biomarkers Prev. , vol.5
    • Wang, J.-S.1
  • 49
    • 15844402238 scopus 로고
    • Seroprevalencia de marcadores de los virus de hepatitis C (VHC) y B (VHB) en donadores de sangre familiares
    • Herrera,F., Juarez-Figureoa,L., Piedras,J. and Mendez,J. (1990) Seroprevalencia de marcadores de los virus de hepatitis C (VHC) y B (VHB) en donadores de sangre familiares. Rev. Gastroenterol. Mex., 54, 312.
    • (1990) Rev. Gastroenterol. Mex. , vol.54 , pp. 312
    • Herrera, F.1    Juarez-Figureoa, L.2    Piedras, J.3    Mendez, J.4
  • 50
    • 15844410407 scopus 로고
    • Prevalencia del antigeno de superficie del virus B de la hepatitis (AgsVBH) en una poblacion hospitalaria
    • Lobato-Mendizaval,E., Marin-Lopez,A. and Labastida-Munoz,H. (1984) Prevalencia del antigeno de superficie del virus B de la hepatitis (AgsVBH) en una poblacion hospitalaria. Rev. Gastroenterol. Mex., 49, 303.
    • (1984) Rev. Gastroenterol. Mex. , vol.49 , pp. 303
    • Lobato-Mendizaval, E.1    Marin-Lopez, A.2    Labastida-Munoz, H.3
  • 51
    • 0025503697 scopus 로고
    • Seroprevalence of viral markers of hepatitis B among health professionals. Multicenter study in Mexico
    • Kershenobich,D. et al. (1990) Seroprevalence of viral markers of hepatitis B among health professionals. Multicenter study in Mexico. Rev. Invest. Clin., 42, 251-256.
    • (1990) Rev. Invest. Clin. , vol.42 , pp. 251-256
    • Kershenobich, D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.