A continuous intracerebral gene delivery system for in vivo liposome-mediated gene therapy

Gene Therapy

Volumn 3, Issue 6, 1996, Pages 472-476

  Zhu, J ^a   Zhang, L ^a   Hanisch, U K ^a   Felgner, P L ^b   Reszka, R ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b Vical   (United States)

Author keywords

Cationic liposome; Continuous delivery; Glioma; In vivo gene therapy; Minipump; Thymidine kinase

Indexed keywords

GANCICLOVIR; LIPOSOME; RECOMBINANT DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN; CONTROLLED STUDY; GENE TARGETING; GENE THERAPY; GENE TRANSFER; GLIOMA; HUMAN; HUMAN CELL; INTRACEREBRAL DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MINIPUMP; NONHUMAN; PATHOLOGY; PRIORITY JOURNAL; RAT; SAFETY; STEREOTAXIC SURGERY; TOXICITY; TUMOR REGRESSION; TUMOR VOLUME;

ANIMALS; ANTIVIRAL AGENTS; BRAIN NEOPLASMS; CELL SURVIVAL; DNA, VIRAL; GANCICLOVIR; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GLIOMA; HUMANS; LAC OPERON; LIPIDS; LIPOSOMES; PHOSPHATIDYLETHANOLAMINES; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, INBRED F344; SIMPLEXVIRUS; STEREOTAXIC TECHNIQUES; THYMIDINE KINASE;

EID: 0029888339     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Crystal RG. Transfer of genes to humans: early lessons and obstacles to success. Science 1995; 270: 404-410.
2. Feigner JH et al. Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations. J Biol Chem 1994; 269: 2550-2561.
3. Nabel GJ et al. Immunotherapy for cancer by direct gene transfer into rumors. Hum Gene Ther 1994; 5: 57-77.
4. Vogelzang NL et al. Phase I study of immunotherapy of metastatic renal cell carcinoma by direct gene transfer into metastatic lesions. Hum Gene Ther 1994; 5: 1357-1370.
5. Hersh EM et al. Phase I study of immunotherapy of malignant melanoma by direct gene transfer. Hum Gene Ther 1994; 5: 1371-1384.
6. Rubin J et al. Phase I study of immunotherapy of hepatic metastases of colorectal carcinoma by direct gene transfer. Hum Gene Ther 1994; 5: 1385-1399.
7. Mahaley MS Jr et al. National survey on patterns of care for brain-tumor patients. J Neurosurg 1989; 71: 826-836.
8. Salcman M. Epidemiology and factors affecting survival. In: Apuzzo MLJ (ed). Malignant Cerebral Glioma. Park Ridge: IL, 1990, pp 95-110.
9. Ezzeddine ZD et al. Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene. New Biol 1991; 3: 608-614.
10. Culver KW et al. In vivo gene transfer with retro viral vector-producer cells for treatment of experimental brain tumors. Science 1992; 256: 1550-1552.
11. Chen S-H et al. Gene therapy for brain tumors: regression of experimental gliomas with adenovirus-mediated gene transfer in vivo. Proc Natl Acad Sci USA 1994; 91: 3054-3057.
12. Efstathios J et al. Long-term survival of rats harbouring brain neoplasms treated with ganciclovir and a herpes simplex virus vector that retains an intact thymidine kinase gene. Cancer Res 1994; 54: 5745-5751.
13. Marshall E. The trouble with vectors. Science 1995; 269: 1052-1053.
14. Pollark P et al. External and implanted pumps for apromorphine infusion in parkinsonism. Acta Neurochir (Wien) 1993; 58: 48-52.
15. Lunetta M, Di-Mauro M, Le-Mol R. Effects of octreotide on blood glucose level in poorly compensated insulin-dependent diabetics on insulin treatment. Menerva Endocrinol 1992; 17: 7-12.
16. Lemay A et al. Escape from the down-regulation of the pituitary-ovarian axis following decreased infusion of luteinizing hormone-releasing hormone agonist. Fertil Steril 1988; 49: 802-808.
17. Schulman S et al. Monoclonal purified F VIII for continuous infusion: stability, microbiological safety and clinical experience. Thromb Haemost 1994; 72: 403-407.
18. Reszka R, Zhu J, Weber F, Walther W. Liposome mediated transfer of marker and cytokine genes into rat and human glioblastoma cells in vitro and in vivo. J Liposome Res 1995; 5: 149-167.
19. Ko L, Koestner A, Wechsler W. Characterization of cell cycle and biological parameters of transplantation glioma cell lines clones. Acta Neuropathol 1980; 51: 107-111.
20. Westphal M, Haesel M, Kunzmann R, Hoelzel F. Karyotype analyses of 20 human glioma cell lines . Acta Neurochir (Wien) 1993; 126: 17-26.