-
1
-
-
33748577758
-
Sequence-specific recognition and modification of double-helical DNA by oligonucleotides
-
Thuong NT, Hélène C: Sequence-specific recognition and modification of double-helical DNA by oligonucleotides. Angew Chem Int Ed 1993, 32:666-690.
-
(1993)
Angew Chem Int Ed
, vol.32
, pp. 666-690
-
-
Thuong, N.T.1
Hélène, C.2
-
2
-
-
0029132791
-
DNA analogues with nonphosphodiester backbones
-
Nielsen PE: DNA analogues with nonphosphodiester backbones. Annu Rev Biophys Biomol Struct 1995, 24:167-183.
-
(1995)
Annu Rev Biophys Biomol Struct
, vol.24
, pp. 167-183
-
-
Nielsen, P.E.1
-
3
-
-
0027197574
-
Oligonucleotide-directed triple helix formation
-
Sun JS, Hélène C: Oligonucleotide-directed triple helix formation. Curr Opin Struct Biol 1993, 3:345-356.
-
(1993)
Curr Opin Struct Biol
, vol.3
, pp. 345-356
-
-
Sun, J.S.1
Hélène, C.2
-
4
-
-
0028781381
-
DNA triplexes: Solution structure, hydration, energetics interactions and function
-
Radhakrishnan I, Patel DJ: DNA triplexes: solution structure, hydration, energetics interactions and function. Biochemistry 1994, 33:11405-11416.
-
(1994)
Biochemistry
, vol.33
, pp. 11405-11416
-
-
Radhakrishnan, I.1
Patel, D.J.2
-
6
-
-
0029610659
-
A nucleic acid triple helix formed by a peptide nucleic acid-DNA complex
-
Betts L, Josey JA, Veal JM, Jordan SR: A nucleic acid triple helix formed by a peptide nucleic acid-DNA complex. Science 1995, 270:1838-1841. This crystal structure of a stable 1:2 DNA-PNA complex involving a purine oligodeoxynucleotide and a hairpin pyrimidine PNA has the following characteristics: both Watson-Crick and Hoogsteen base pairing occur; the triplex is underwound with a base tilt similar to that of B-DNA; the bases are displaced from the helix axis even more than in A-DNA; and there are hydrogen bonds between the DNA backbone and the Hoogsteen PNA backbone.
-
(1995)
Science
, vol.270
, pp. 1838-1841
-
-
Betts, L.1
Josey, J.A.2
Veal, J.M.3
Jordan, S.R.4
-
7
-
-
0343010169
-
FTIR spectroscopy structural study of triple helices obtained by targeting the d(GGGAAAAGGG) oligomer
-
Edited by Sarma RH, Sarma MH. New York: Adenine Press
-
Dagneaux C, Liquier J, Scaria PV, Shafer RH, Taillandier E: FTIR spectroscopy structural study of triple helices obtained by targeting the d(GGGAAAAGGG) oligomer. In Structural Biology: State of the Art. Edited by Sarma RH, Sarma MH. New York: Adenine Press; 1994:103-113.
-
(1994)
Structural Biology: State of the Art
, pp. 103-113
-
-
Dagneaux, C.1
Liquier, J.2
Scaria, P.V.3
Shafer, R.H.4
Taillandier, E.5
-
8
-
-
0028828793
-
FTIR study of a nonclassical dT10*dA10-dT10 intramolecular triple helix
-
Dagneaux C, Liquier J, Taillandier E: FTIR study of a nonclassical dT10*dA10-dT10 intramolecular triple helix. Biochemistry 1995, 34:14815-14818.
-
(1995)
Biochemistry
, vol.34
, pp. 14815-14818
-
-
Dagneaux, C.1
Liquier, J.2
Taillandier, E.3
-
10
-
-
0027715886
-
Stability of triple helices containing RNA and DNA strands: Experimental and molecular modeling studies
-
Escudé C, François JC, Sun JS, Ott G, Sprinzl M, Garestier T, Hélène C: Stability of triple helices containing RNA and DNA strands: experimental and molecular modeling studies. Nucleic Acids Res 1993, 21:5547-5553.
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 5547-5553
-
-
Escudé, C.1
François, J.C.2
Sun, J.S.3
Ott, G.4
Sprinzl, M.5
Garestier, T.6
Hélène, C.7
-
11
-
-
0029029235
-
Spectroscopic studies of chimeric DNA-RNA and RNA 29-base intramolecular triple helices
-
Liquier J, Taillandier E, Klinck R, Guittet E, Gouyette C, Huynh-Dinh T: Spectroscopic studies of chimeric DNA-RNA and RNA 29-base intramolecular triple helices. Nucleic Acids Res 1995, 23:1722-1728.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 1722-1728
-
-
Liquier, J.1
Taillandier, E.2
Klinck, R.3
Guittet, E.4
Gouyette, C.5
Huynh-Dinh, T.6
-
12
-
-
0029619427
-
Sugar conformation in DNA and RNA-DNA triple helices determined by FTIR spectroscopy: Role of backbone composition
-
Dagneaux C, Liquier J, Taillandier E: Sugar conformation in DNA and RNA-DNA triple helices determined by FTIR spectroscopy: role of backbone composition. Biochemistry 1995, 34:16618-16623.
-
(1995)
Biochemistry
, vol.34
, pp. 16618-16623
-
-
Dagneaux, C.1
Liquier, J.2
Taillandier, E.3
-
14
-
-
0029129809
-
Nucleic acid hybridization: Triplex stability and energetics
-
Plum GE, Pilch DS, Singleton SF, Breslauer KJ: Nucleic acid hybridization: triplex stability and energetics. Annu Rev Biophys Biomol Struct 1995, 24:319-350.
-
(1995)
Annu Rev Biophys Biomol Struct
, vol.24
, pp. 319-350
-
-
Plum, G.E.1
Pilch, D.S.2
Singleton, S.F.3
Breslauer, K.J.4
-
15
-
-
11944253600
-
Energetics of formation of sixteen triple helical complexes which vary at a single position within a pyrimidine motif
-
Best GC, Dervan PB: Energetics of formation of sixteen triple helical complexes which vary at a single position within a pyrimidine motif. J Am Chem Soc 1995, 117:1187-1193.
-
(1995)
J Am Chem Soc
, vol.117
, pp. 1187-1193
-
-
Best, G.C.1
Dervan, P.B.2
-
16
-
-
0000487117
-
Energetics of formation of sixteen triple helical complexes which vary at a single position within a purine motif
-
Greenberg WA, Dervan PB: Energetics of formation of sixteen triple helical complexes which vary at a single position within a purine motif. J Am Chem Soc 1995, 117:5016-5022.
-
(1995)
J Am Chem Soc
, vol.117
, pp. 5016-5022
-
-
Greenberg, W.A.1
Dervan, P.B.2
-
17
-
-
0029136132
-
Cooperative triple helix formation at adjacent DNA sites: Sequence composition dependence at the junction
-
Colocci N, Dervan PB: Cooperative triple helix formation at adjacent DNA sites: sequence composition dependence at the junction. J Am Chem Soc 1995, 117:4781-4787. This paper describes sequence effect and energetics of the binding cooperativily to adjacent DNA sites within a parallel (C,T)-motif triplex using a quantitative DNase I footprinting assay. The cooperative binding of two third-strand oligonucleotides is more sensitive to single base mismatches at the junction than triplexes involving single oligonucleotides of same total length with a mismatch at the same position.
-
(1995)
J Am Chem Soc
, vol.117
, pp. 4781-4787
-
-
Colocci, N.1
Dervan, P.B.2
-
18
-
-
0028904989
-
Origins of the large differences in stability of DNA and RNA helices: C-5 methyl and 2′-hydroxyl effects
-
Wang SH, Kool ET: Origins of the large differences in stability of DNA and RNA helices: C-5 methyl and 2′-hydroxyl effects. Biochemistry 1995, 34:4125-4132. The dissection of the C5-methyl and 2′-hydroxyl effects on the stability of the DNA-RNA duplex and triplex hybrids. The two substitutions act, in general, independently of each other: the C5-methyl group of thymine is, in all cases, stabilizing, whereas the 2′-OH groups can be either stabilizing or destabilizing, depending on the type of RNA-DNA duplex and triplex.
-
(1995)
Biochemistry
, vol.34
, pp. 4125-4132
-
-
Wang, S.H.1
Kool, E.T.2
-
20
-
-
0029040552
-
An unusually stable purine(purine-pyrimidine) short triplex
-
Svinarchuk F, Paoletti J, Malvy C: An unusually stable purine(purine-pyrimidine) short triplex. J Biol Chem 1995, 270:14068-14071. An oligodeoxynucleotide of sequence 5′-GGAGGGGGAGGGG-3′ binds very strongly to its target oligopurineoligopyrimidine sequence under physiological conditions.
-
(1995)
J Biol Chem
, vol.270
, pp. 14068-14071
-
-
Svinarchuk, F.1
Paoletti, J.2
Malvy, C.3
-
21
-
-
0028786594
-
The high stability of the triple helices formed between short purine oligonucleotides and SIV/HIV-2 vpx genes is determined by the target DNA structure
-
Svinarchuk F, Monnot M, Merle A, Malvy C, Fermandjian S: The high stability of the triple helices formed between short purine oligonucleotides and SIV/HIV-2 vpx genes is determined by the target DNA structure. Nucleic Acids Res 1995, 23:3831-3836.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 3831-3836
-
-
Svinarchuk, F.1
Monnot, M.2
Merle, A.3
Malvy, C.4
Fermandjian, S.5
-
22
-
-
0027971991
-
Oligodeoxyribonucleotide length and sequence effects on intermolecular purine-purine-pyrimidine triple-helix formation
-
Cheng AJ, Van Dyke MW: Oligodeoxyribonucleotide length and sequence effects on intermolecular purine-purine-pyrimidine triple-helix formation. Nucleic Acids Res 1994, 22:4742-4747.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 4742-4747
-
-
Cheng, A.J.1
Van Dyke, M.W.2
-
23
-
-
0028908671
-
Competitive triplex/quadruplex equilibria involving guanine-rich oligonucleotides
-
Olivas WM, Maher LJ: Competitive triplex/quadruplex equilibria involving guanine-rich oligonucleotides. Biochemistry 1995, 34:278-284.
-
(1995)
Biochemistry
, vol.34
, pp. 278-284
-
-
Olivas, W.M.1
Maher, L.J.2
-
24
-
-
0029034982
-
Overcoming potassium-mediated triplex inhibition
-
Olivas WM, Maher LJ: Overcoming potassium-mediated triplex inhibition. Nucleic Acids Res 1995, 23:1936-1941.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 1936-1941
-
-
Olivas, W.M.1
Maher, L.J.2
-
25
-
-
0028934881
-
Incorporation of 2′-deoxy-6-thioguanine into G-rich oligodeoxyribonucleotides inhibits G-tetrad formation and facilitates triplex formation
-
Rao TS, Durland RH, Seth DM, Myrick MA, Bodepudi V, Revankar GR: Incorporation of 2′-deoxy-6-thioguanine into G-rich oligodeoxyribonucleotides inhibits G-tetrad formation and facilitates triplex formation. Biochemistry 1995, 34:765-772.
-
(1995)
Biochemistry
, vol.34
, pp. 765-772
-
-
Rao, T.S.1
Durland, R.H.2
Seth, D.M.3
Myrick, M.A.4
Bodepudi, V.5
Revankar, G.R.6
-
26
-
-
0029015499
-
Effect of competing self-structure on triplex formation with purine-rich oligodeoxynucleotides containing GA repeats
-
Noonberg SB, François JC, Garestier T, Hélène C: Effect of competing self-structure on triplex formation with purine-rich oligodeoxynucleotides containing GA repeats. Nucleic Acids Res 1995, 23:1956-1963.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 1956-1963
-
-
Noonberg, S.B.1
François, J.C.2
Garestier, T.3
Hélène, C.4
-
27
-
-
0026697386
-
Alternating d(G-A) sequences form a parallel-stranded DNA duplex
-
Rippe K, Frisch V, Westhof E, Jovin TM: Alternating d(G-A) sequences form a parallel-stranded DNA duplex. EMBO J 1992, 11:3777-3786.
-
(1992)
EMBO J
, vol.11
, pp. 3777-3786
-
-
Rippe, K.1
Frisch, V.2
Westhof, E.3
Jovin, T.M.4
-
29
-
-
0029082563
-
Intramolecular folding of pyrimidine oligodeoxynucleotides into an i-DNA motif
-
Mergny JL, Lacroix L, Han XG, Leroy JL, Hélène C: Intramolecular folding of pyrimidine oligodeoxynucleotides into an i-DNA motif. J Am Chem Soc 1995, 117:8887-8898.
-
(1995)
J Am Chem Soc
, vol.117
, pp. 8887-8898
-
-
Mergny, J.L.1
Lacroix, L.2
Han, X.G.3
Leroy, J.L.4
Hélène, C.5
-
30
-
-
0028558883
-
Direct measurement of thermodynamic and kinetic parameters of DNA triple helix formation by fluorescence spectroscopy
-
Yang M, Ghosh SS, Millar DP: Direct measurement of thermodynamic and kinetic parameters of DNA triple helix formation by fluorescence spectroscopy. Biochemistry 1994, 33:15329-15337. This paper describes the direct measurement of thermodynamic and kinetic data for triplex formation by FRET using fluorophore-labelled oligonucleotides.
-
(1994)
Biochemistry
, vol.33
, pp. 15329-15337
-
-
Yang, M.1
Ghosh, S.S.2
Millar, D.P.3
-
31
-
-
0028559132
-
Fluorescence energy transfer between two triple helix-forming oligonucleotides bound to duplex DNA
-
Mergny JL, Garestier T, Rougée M, Lebedev AV, Chassignol M, Thuong NT, Hélène C: Fluorescence energy transfer between two triple helix-forming oligonucleotides bound to duplex DNA. Biochemistry 1994, 33:15321-15328.
-
(1994)
Biochemistry
, vol.33
, pp. 15321-15328
-
-
Mergny, J.L.1
Garestier, T.2
Rougée, M.3
Lebedev, A.V.4
Chassignol, M.5
Thuong, N.T.6
Hélène, C.7
-
32
-
-
0029050973
-
Detection and kinetic studies of triplex formation by oligodeoxynucleotides using real-time biomolecular interaction analysis (BIA)
-
Bates PJ, Dosanjh HS, Kumar S, Jenkins TC, Laughton CA, Neidle S: Detection and kinetic studies of triplex formation by oligodeoxynucleotides using real-time biomolecular interaction analysis (BIA). Nucleic Acids Res 1995, 23:3627-3632. This work demonstrates the utility of biosensor technology to quantitatively investigate the kinetics of triplex formation.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 3627-3632
-
-
Bates, P.J.1
Dosanjh, H.S.2
Kumar, S.3
Jenkins, T.C.4
Laughton, C.A.5
Neidle, S.6
-
33
-
-
0028585986
-
5oxC) for the pH-independent recognition of G-C base pairs by oligonucleotide-directed triplex formation
-
5oxC) for the pH-independent recognition of G-C base pairs by oligonucleotide-directed triplex formation. J Am Chem Soc 1994, 116:11155-11156.
-
(1994)
J Am Chem Soc
, vol.116
, pp. 11155-11156
-
-
Xiang, G.B.1
Soussou, W.2
McLaughlin, L.W.3
-
34
-
-
0029029713
-
6-oxocytosine a novel protonated C-base analogue for stable triple helix formation
-
Berressem R, Engels JW: 6-oxocytosine a novel protonated C-base analogue for stable triple helix formation. Nucleic Acids Res 1995, 23:3465-3472.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 3465-3472
-
-
Berressem, R.1
Engels, J.W.2
-
35
-
-
0028986580
-
Design of an N7-glycosylated purine nucleoside for recognition of GC base pairs by triple helix formation
-
Hunziker J, Priestley ES, Brunar H, Dervan PB: Design of an N7-glycosylated purine nucleoside for recognition of GC base pairs by triple helix formation. J Am Chem Soc 1995, 117:2661-2662.
-
(1995)
J Am Chem Soc
, vol.117
, pp. 2661-2662
-
-
Hunziker, J.1
Priestley, E.S.2
Brunar, H.3
Dervan, P.B.4
-
36
-
-
0028997796
-
Sequence composition effects on the energetics of triple helix formation by oligonucleotides containing a designed mimic of protonated cytosine
-
Priestley ES, Dervan PB: Sequence composition effects on the energetics of triple helix formation by oligonucleotides containing a designed mimic of protonated cytosine. J Am Chem Soc 1995, 117:4761-4765. Sequence context dictates the selection of a pH-independent mimic of protonated cytosine (N7-glycosylated,8-aza,9-deazamethylguanine) versus pH-dependent C5-methylcytosine to obtain stable triplexes.
-
(1995)
J Am Chem Soc
, vol.117
, pp. 4761-4765
-
-
Priestley, E.S.1
Dervan, P.B.2
-
37
-
-
0026739476
-
Triple helix formation by oligonucleotides containing three bases thymine, cytosine and guanine
-
Giovannangeli C, Rougée M, Garestier T, Thuong NT, Hélène C: Triple helix formation by oligonucleotides containing three bases thymine, cytosine and guanine. Proc Natl Acad Sci USA 1992, 89:8631-8635.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 8631-8635
-
-
Giovannangeli, C.1
Rougée, M.2
Garestier, T.3
Thuong, N.T.4
Hélène, C.5
-
38
-
-
0028796588
-
Model studies toward a general triplex DNA recognition scheme: A novel DNA base that binds a CG base-pair in an organic solvent
-
Zimmerman SC, Schmitt P: Model studies toward a general triplex DNA recognition scheme: a novel DNA base that binds a CG base-pair in an organic solvent J Am Chem Soc 1995, 117:10769-10770.
-
(1995)
J Am Chem Soc
, vol.117
, pp. 10769-10770
-
-
Zimmerman, S.C.1
Schmitt, P.2
-
39
-
-
0029586169
-
Design of a novel artificial nucleobase for the selective formation of a triple-complex with a cytosine-guanine base pair
-
Sasaki S, Nakashima S, Nagatsugi F, Tanaka Y, Hisatome M, Maeda M: Design of a novel artificial nucleobase for the selective formation of a triple-complex with a cytosine-guanine base pair. Tetrahedron Lett 1995, 36:9521-9524.
-
(1995)
Tetrahedron Lett
, vol.36
, pp. 9521-9524
-
-
Sasaki, S.1
Nakashima, S.2
Nagatsugi, F.3
Tanaka, Y.4
Hisatome, M.5
Maeda, M.6
-
40
-
-
0028983405
-
Oligonucleotide N3′→P5′ phosphoramidates
-
Gryaznov SM, Lloyd DH, Chen JK, Schultz RG, DeDionisio LA, Ratmeyer L, Wilson WD: Oligonucleotide N3′→P5′ phosphoramidates. Proc Natl Acad Sci USA 1995, 92:5798-5802.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5798-5802
-
-
Gryaznov, S.M.1
Lloyd, D.H.2
Chen, J.K.3
Schultz, R.G.4
DeDionisio, L.A.5
Ratmeyer, L.6
Wilson, W.D.7
-
41
-
-
0029958890
-
Stable triple-helices formed by Oligonucleotide N3P5 phosphoramidates inhibit transcription elongation
-
in press
-
Escudé C, Giovannangeli C, Sun JS, Lloyd DH, Chen JK, Gryaznov SM, Garestier T, Hélène C: Stable triple-helices formed by Oligonucleotide N3P5 phosphoramidates inhibit transcription elongation. Proc Natl Acad Sci USA 1996, in press. The N3′→P5′ phosphoramidate backbone modification (see [40]) greatly enhances the stability of triple-helical complexes formed by phosphoramidates as compared to isosequential phosphodiesters. An in vitro eukaryotic transcription assay is used to demonstrate that backbone-modified oligonucleotides (with N3′→P′ phosphoramidate linkages) can be used to efficiently inhibit transcription elongation by eukaryotic RNA polymerase II at submicromolar concentrations.
-
(1996)
Proc Natl Acad Sci USA
-
-
Escudé, C.1
Giovannangeli, C.2
Sun, J.S.3
Lloyd, D.H.4
Chen, J.K.5
Gryaznov, S.M.6
Garestier, T.7
Hélène, C.8
-
42
-
-
0029036905
-
Synthesis of a thymidyl pentamer of deoxyribonucleic guanidine and binding studies with DNA homopolynucleotides
-
Dempcy RO, Browne KA, Bruice TC: Synthesis of a thymidyl pentamer of deoxyribonucleic guanidine and binding studies with DNA homopolynucleotides. Proc Natl Acad Sci USA 1995, 92:6097-6101. The replacement of anionic phosphodiester linkages with cationic guanidine linkers dramatically increases the stability of the complexes formed by deoxyribonucleic guanidine derivatives with single- or double-stranded DNA.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 6097-6101
-
-
Dempcy, R.O.1
Browne, K.A.2
Bruice, T.C.3
-
43
-
-
0028801202
-
Stable triple helices formed by acridine-containing oligonucleotides with oligopurine tracts of DNA interrupted by one or two pyrimidines
-
Zhou BW, Puga E, Sun JS, Garestier T, Hélène C: Stable triple helices formed by acridine-containing oligonucleotides with oligopurine tracts of DNA interrupted by one or two pyrimidines. J Am Chem Soc 1995, 117:10425-10428.
-
(1995)
J Am Chem Soc
, vol.117
, pp. 10425-10428
-
-
Zhou, B.W.1
Puga, E.2
Sun, J.S.3
Garestier, T.4
Hélène, C.5
-
44
-
-
0029360346
-
Recognition of alternating oligopurine/oligopyrimidine tracts of DNA by oligonucleotides with base-to-base linkages
-
Zhou BW, Marchand C, Asseline U, Thuong NT, Sun JS, Garestier T, Hélène C: Recognition of alternating oligopurine/oligopyrimidine tracts of DNA by oligonucleotides with base-to-base linkages. Bioconjug Chem 1995, 6:516-523. A new concept, based on base-to-base linkages, to design and synthesize switch oligonucleotides for alternate strand recognition by triplex formation is presented.
-
(1995)
Bioconjug Chem
, vol.6
, pp. 516-523
-
-
Zhou, B.W.1
Marchand, C.2
Asseline, U.3
Thuong, N.T.4
Sun, J.S.5
Garestier, T.6
Hélène, C.7
-
45
-
-
0342575941
-
Rational design of switched triple helix-forming oligonucleotides: Extension of sequences for triple helix formation
-
Edited by Pullman A, Pullman 8, Jortner J. London: Kluwer Academic Publishers
-
Sun JS: Rational design of switched triple helix-forming oligonucleotides: extension of sequences for triple helix formation. In Modelling of Biomolecular Structures and Mechanisms. Edited by Pullman A, Pullman 8, Jortner J. London: Kluwer Academic Publishers; 1995:267-288. This modeling study describes alternate-strand recognition by triplex formation and the rational design of switch oligonucleotides to optimize binding at the junctions. A 'switch code' establishing the rules for forming stable triplexes at alternating oligopurine/oligopyrimidine sequences is proposed under various sequence contexts using standard nucleotides at the junctions.
-
(1995)
Modelling of Biomolecular Structures and Mechanisms
, pp. 267-288
-
-
Sun, J.S.1
-
46
-
-
0028158755
-
DNA recognition by alternate strand triple helix formation: Affinities of oligonucleotides for a site in the human p53 gene
-
Olivas WM, Maher LJ: DNA recognition by alternate strand triple helix formation: affinities of oligonucleotides for a site in the human p53 gene. Biochemistry 1994, 33:983-991.
-
(1994)
Biochemistry
, vol.33
, pp. 983-991
-
-
Olivas, W.M.1
Maher, L.J.2
-
47
-
-
0029990185
-
Alternate-strand DNA triple-helix mediated inhibition of HIV-1 U5 LTR integration in vitro
-
in press
-
Bouziane M, Cherny Dl, Mouscadet JF, Auclair C: Alternate-strand DNA triple-helix mediated inhibition of HIV-1 U5 LTR integration in vitro. J Biol Chem 1996, in press. An in vitro assay describing the efficient inhibition of retroviral integration by an intercalator-oligonucleotide conjugate targeted to the HIV-1 U5 LTR integration site via switch triplex formation.
-
(1996)
J Biol Chem
-
-
Bouziane, M.1
Cherny, Dl.2
Mouscadet, J.F.3
Auclair, C.4
-
48
-
-
0029016341
-
Triple helix DNA alters nucleosomal histone-DNA interactions and acts as a nucleosome barrier
-
Westin L, Blomquist P, Milligan JF, Wrange Ö: Triple helix DNA alters nucleosomal histone-DNA interactions and acts as a nucleosome barrier. Nucleic Acids Res 1995, 23:2184-2191. An in vitro assay that describes how triplex formation interferes with nucleosome organization.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 2184-2191
-
-
Westin, L.1
Blomquist, P.2
Milligan, J.F.3
Wrange, Ö.4
-
49
-
-
0027986871
-
Efficient unwinding of triplex DNA by a DNA helicase
-
Maine IP, Kodadek T: Efficient unwinding of triplex DNA by a DNA helicase. Biochem Biophys Res Commun 1994, 204:1119-1124.
-
(1994)
Biochem Biophys Res Commun
, vol.204
, pp. 1119-1124
-
-
Maine, I.P.1
Kodadek, T.2
-
50
-
-
0029966659
-
Unwinding of the third strand of a DNA triple helix, a novel activity of the SV40 large T-antigen helicase
-
Kopel V, Pozner A, Barab N, Manor H: Unwinding of the third strand of a DNA triple helix, a novel activity of the SV40 large T-antigen helicase. Nucleic Acids Res 1996, 24:330-335. The authors describe an in vitro assay that shows that the unwinding of a DNA triplex by the SV40 large T-antigen helicase requires the binding of the helicase to a single-stranded flanking sequence on the 3′-side of the third-strand oligonucleotide.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 330-335
-
-
Kopel, V.1
Pozner, A.2
Barab, N.3
Manor, H.4
-
51
-
-
0028859271
-
Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation
-
Wang G, Levy DD, Seidman MM, Glazer PM: Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation. Mol Cell Biol 1995, 15:1759-1768.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1759-1768
-
-
Wang, G.1
Levy, D.D.2
Seidman, M.M.3
Glazer, P.M.4
-
52
-
-
0029113990
-
Altered repair of targeted psoralen photoadducts in the context of an oligonucleotide-mediated triple helix
-
Wang G, Glazer PM: Altered repair of targeted psoralen photoadducts in the context of an oligonucleotide-mediated triple helix. J Biol Chem 1995, 270:22595-22601. Triplex-forming oligonucleotides tethered to a psoralen derivative can be used to target mutagenesis after UV irradiation to a selected gene carried by a plasmid vector in mammalian cells (see also [51]). The pattern of targeted mutation generated by psoralen-oligonucleotide conjugates via intracellular triplex formation is influenced by the length of the oligonucleotide. The incision steps in nucleotide excision repair in mammalian cells are altered by the presence of an oligonucleotide with sufficient length and binding affinity.
-
(1995)
J Biol Chem
, vol.270
, pp. 22595-22601
-
-
Wang, G.1
Glazer, P.M.2
-
53
-
-
0029170404
-
H-DNA: DNA triplex formation within topologically closed plasmids
-
Broitman SL: H-DNA: DNA triplex formation within topologically closed plasmids. Prog Biophys Mol Biol 1995, 63:119-129.
-
(1995)
Prog Biophys Mol Biol
, vol.63
, pp. 119-129
-
-
Broitman, S.L.1
-
54
-
-
0029036249
-
Occurrence of potential cruciform and H-DNA forming sequences in genomic DNA
-
Schroth GP, Ho PS: Occurrence of potential cruciform and H-DNA forming sequences in genomic DNA. Nucleic Acids Res 1995, 23:1977-1983.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 1977-1983
-
-
Schroth, G.P.1
Ho, P.S.2
-
55
-
-
0028945908
-
An intramolecular triplex structure from non-mirror repeated sequence containing both Py:Pu-Py and Pu:Pu-Py triads
-
Klysik J: An intramolecular triplex structure from non-mirror repeated sequence containing both Py:Pu-Py and Pu:Pu-Py triads. J Mol Biol 1995, 245:499-507.
-
(1995)
J Mol Biol
, vol.245
, pp. 499-507
-
-
Klysik, J.1
-
56
-
-
0028855306
-
Selective stabilization of DNA triple helices by benzopyridoindole derivatives
-
Escudé C, Nguyen CH, Mergny JL, Sun JS, Bisagni E, Garestier T, Hélène C: Selective stabilization of DNA triple helices by benzopyridoindole derivatives. J Am Chem Soc 1995, 117:10212-10219.
-
(1995)
J Am Chem Soc
, vol.117
, pp. 10212-10219
-
-
Escudé, C.1
Nguyen, C.H.2
Mergny, J.L.3
Sun, J.S.4
Bisagni, E.5
Garestier, T.6
Hélène, C.7
-
57
-
-
0028906883
-
Triple-helix specific ligands stabilize H-DNA conformation
-
Duval-Valentin G, De Bizemont T, Takasugi M, Mergny JL, Bisagni E, Hélène C: Triple-helix specific ligands stabilize H-DNA conformation. J Mol Biol 1995, 247:847-858. Triplex-specific ligands can not only stabilize, but can induce, the formation of H-motif DNA under conditions where the B→H transition does not occur. This opens a new field of investigation for searching a novel class of DNA-acting drugs.
-
(1995)
J Mol Biol
, vol.247
, pp. 847-858
-
-
Duval-Valentin, G.1
De Bizemont, T.2
Takasugi, M.3
Mergny, J.L.4
Bisagni, E.5
Hélène, C.6
-
58
-
-
0030061229
-
Ligand-induced formation of Hoogsteen-paired parallel DNA
-
Escudé C, Mohammadi S, Sun JS, Nguyen CH, Bisagni E, Liquier J, Taillandier E, Garestier T, Hélène C: Ligand-induced formation of Hoogsteen-paired parallel DNA. Chem Biol 1996, 3:57-65.
-
(1996)
Chem Biol
, vol.3
, pp. 57-65
-
-
Escudé, C.1
Mohammadi, S.2
Sun, J.S.3
Nguyen, C.H.4
Bisagni, E.5
Liquier, J.6
Taillandier, E.7
Garestier, T.8
Hélène, C.9
-
59
-
-
0028907534
-
Antiparallel, intramolecular triplex DNA stimulates homologous recombination in human cells
-
Rooney SM, Moore PD: Antiparallel, intramolecular triplex DNA stimulates homologous recombination in human cells. Proc Natl Acad Sci USA 1995, 92:2141-2144.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 2141-2144
-
-
Rooney, S.M.1
Moore, P.D.2
-
60
-
-
0027761870
-
Interactions of three strands in joints made by RecA protein
-
Chiu SK, Rao BJ, Story RM, Radding CM: Interactions of three strands in joints made by RecA protein. Biochemistry 1993, 32:13146-13155.
-
(1993)
Biochemistry
, vol.32
, pp. 13146-13155
-
-
Chiu, S.K.1
Rao, B.J.2
Story, R.M.3
Radding, C.M.4
-
61
-
-
0028948224
-
Probing the structure of a putative intermediate in homologous recombination: The third strand in the parallel DNA triplex is in contact with the major groove of the duplex
-
Kim MG, Zhurkin VB, Jernigan RL, Camerini-Otero RD: Probing the structure of a putative intermediate in homologous recombination: the third strand in the parallel DNA triplex is in contact with the major groove of the duplex. J Mol Biol 1995, 247:874-889.
-
(1995)
J Mol Biol
, vol.247
, pp. 874-889
-
-
Kim, M.G.1
Zhurkin, V.B.2
Jernigan, R.L.3
Camerini-Otero, R.D.4
-
62
-
-
0028971084
-
RecA-oligonucleotide filaments bind in the minor groove of double-stranded DNA
-
Baliga R, Singleton JW, Dervan PB: RecA-oligonucleotide filaments bind in the minor groove of double-stranded DNA. Proc Natl Acad Sci USA 1995, 92:10395-10397. This paper describes a convincing experiment demonstrating the location of the incoming homologous strand (third strand) in the minor groove of duplex DNA by the affinity-cleavage reaction using Fe·EDTA tethered to the incoming strand. The 3′-shift of the cleavage sites is a signature of the minor groove location of the incoming homologous strand.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 10395-10397
-
-
Baliga, R.1
Singleton, J.W.2
Dervan, P.B.3
-
63
-
-
0028822134
-
Sequence-specific covaient modification of DNA by cross-linking oligonucleotides. Catalysis by RecA and implication for the mechanism of synaptic joint formation
-
Podyminogin MA, Meyer RB, Gamper HB: Sequence-specific covaient modification of DNA by cross-linking oligonucleotides. Catalysis by RecA and implication for the mechanism of synaptic joint formation. Biochemistry 1995, 34:13098-13108. Experimental evidence using an oligonucleotide tethered to an alkylating reagent is provided that suggests that the incoming homologous strand is located in the minor groove of duplex DNA.
-
(1995)
Biochemistry
, vol.34
, pp. 13098-13108
-
-
Podyminogin, M.A.1
Meyer, R.B.2
Gamper, H.B.3
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