Suppressive Effects of Recombinant Human Monokine Induced by IFN-γ (rHuMig) Chemokine on the Number of Committed and Primitive Hemopoietic Progenitors in Liquid Cultures of CD34+ Human Bone Marrow Cells

Journal of Immunology

Volumn 159, Issue 2, 1997, Pages 895-904

  Schwartz, Gretchen N ^a   Liao, Fang ^b   Gress, Ronald E ^a   Farber, Joshua M ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CHEMOKINE; CD34 ANTIGEN; CHEMOKINE; CXCL9 PROTEIN, HUMAN; RECOMBINANT PROTEIN; SIGNAL PEPTIDE;

ARTICLE; BONE MARROW; BONE MARROW CELL; CELL COUNT; CELL CULTURE; CYTOLOGY; DRUG EFFECT; HEMATOPOIETIC STEM CELL; HUMAN;

ANTIGENS, CD34; BONE MARROW; BONE MARROW CELLS; CELL COUNT; CELLS, CULTURED; CHEMOKINES; CHEMOKINES, CXC; HEMATOPOIETIC STEM CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; RECOMBINANT PROTEINS;

EID: 0031570869     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Sutherland, H. J., A. C. Eaves, and C. J. Eaves. 1991. Quantitative assays for human hemopoietic progenitor cells. In Bone Marrow Processing and Purging: A Practical Guide. A. P. Gee, ed. CRC Press, Boca Raton, FL, p. 155.
2. Civin, C. I., and S. D. Gore. 1993. Antigenic analysis of hematopoiesis: a review. J. Hematother. 2:137.
3. - cells reselected from macrophage inflammatory protein-1α + interleukin-3-supplemented "stromanoncontact" cultures are highly enriched for long-term bone marrow culture initiating cells. Blood 84:1442.
4. + hematopoietic cells. Exp. Hematol. 20:24.
5. Mayani, H., L. J. Guilbert, and A. Janowska-Eieczorek. 1992. Biology of the hemopoietic microenvironment. Eur. J. Haematol. 49:225.
6. Farber, J. M. 1990. A macrophage mRNA selectively induced by γ-interferon encodes a member of the platelet factor 4 family of cytokines. Proc. Natl. Acad. Sci. USA 87:5238.
7. Farber, J. M. 1993. HuMIG: a new human member of the chemokine family of cylokines. Biochem. Biophys. Res. Commum. 192:223.
8. Liao, F., R. L. Rabin, J. R. Yannelli, L. G. Koniaris, P. Vanguri, and J. M. Farber. 1995. Human Mig chemokine: biochemical and functional characterization. J. Exp. Med. 182:1301.
9. Amichay, D., R. T. Gazzinelli, G. Karupiah, T. R. Moench, A. Sher, and J. M. Farber. 1996. The genes for chemokines MuMig and Crg-2 are induced in protozoan and viral infections in response to IFN-γ with patterns of tissue expression that suggest nonredundant roles in vivo. J. Immunol. 157:4511.
10. Gewirtz, A. M., J. Zhang, J. Ralajczak, M. Ratajczak, K. S. Park, C. Li, Z. Yan, and M. Poncz. 1995. Chemokine regulation of human megakaryocytopoiesis. Blood 86:2559.
11. Broxmeyer, H. E., B. Sherry, S. Cooper, L. Lu, R. Maze, M. P. Beckmann, A. Cerami, and P. Ralph. Comparative analysis of human macrophage inflammatory protein family of cytokines (chemokines) on proliferation of human myeloid progenitor cells. J. Immunol. 150:3448.
12. Daly, J. T., J. LaRosa, S. Dolich, T. E. Maione, S. Cooper, and H. E. Broxmeyer. 1995. High activity suppression of myeloid progenitor proliferation hy chimeric mutants of interleukin 8 and platelet factor 4. J. Biol. Chem. 270:23282.
13. +++ stem/progenitor cells from human hone marrow and umbilical cord blood plated with and without serum. Exp. Hematol. 21:1442.
14. Sarris, A. H., H. E. Broxmeyer, U. Wirthmueller, N. Karasavvas, S. Copper, L. Lu, J. Drueger, and J. C. Ravetch. 1993. Human interferon-inducible protein 10: expression and publication of recombinant protein demonstrate inhibition of early human hematopoietic progenitors. J. Exp. Med. 178:1127.
15. Sarris, A. H., M. Talpaz, A. B. Deisseroth, and Z. Estrov. 1996. Human recombinant inrerferon-inducible protein-10 inhibits the proliferation of normal and acute myelogenous leukemia. Leukemia 10:757.
16. + progenitors. Exp. Hematol. 23:551.
17. Keller, J. R., S. H. Bartelmez, W. Sitnicka, F. W. Ruscetti, M. Ortiz, J. M. Gooya, and S. E. W. Jacobsen. 1994. Distinct and overlapping direct effects of macrophage inflammatory protein-1α and transforming growth factor β on hematopoietic progenitor/stem cell growth. Blood 84:2175.
18. Maltman, J., I. B. Pragnell, and G. J. Graham. 1993. Transforming growth factor β: is it a down-regulator of stem cell inhibition by macrophage inflammatory protein-1α? J. Exp. Med. 178:925.
19. Lord, B. I. 1995. MIP-1α increases the self-renewal capacity of the hemopoietic spleen-colony-forming cells following hydroxyurea treatment in vivo. Growth Factors 12:145.
20. Hunter, M. G., L. Bawden, D. Brotherton, S. Craig, S. Cribbes, L. G. Czaplewski, T. M. Dexter, A. H. Drummond, A. H. Gearing, C. M. Heyworth, B. I. Lord, M. McCourt, P. G. Varlery, L. M. Wood, R. M. Edwards, and P. J. Lewis. 1995. BB-10010: an active variant of human macrophage inflammatory protein-1α with improved pharmaceutical properties. Blood 86:4400.
21. Broxmeyer, H. K. 1992. Suppressor cytokines and regulation of myelopoiesis: biology and possible clinical uses. Am. J. Pediatr. Hematol. Oncol. 14:22.
22. Khoury, E., F. M. Lemoine, C. Baillou, L. Kobari, J. Deloux, M. Guigon, and A. Najman. 1992. Tumor necrosis factor alpha in human long-term marrow cultures: distinct effects on nonadherent and adherent progenitors. Exp. Hematol. 20:991.
23. Schwartz, G. N., S. W. Kessler, J. M. Szabo, L. M. Burrell, and M. L. Francis. 1995. Negative regulators may mediate some of the inhibitory effects of HIV-1-infected stromal cell layers on erythropoiesis and myelopoiesis in human bone marrow long term cultures (LTC). J. Leukocyte Biol. 57:948.
24. Toretsky, J. A., N. T. Shahidi, and J. L. Finlay. 1986. Effects of recombinant human interferon gamma on hematopoietic progenitor cell growth. Exp. Hematol. 14:182.
25. - cells cultured with interleukin-3, granulocyte colony-stimulating factor, or granulocyte-macrophage colony-stimulating factor. Blood 77:2316.
26. Schwartz, G. N. 1989. Use of Gel-Well culture chambers as a liquid culture system to measure response of hematopoietic colony-forming cells to growth factors. Int. J. Cell Cloning 7:360.
27. Schwartz, G. N., W. R. Hudgins, and J. F. Perdue. 1993. Glycosylated insulin-like growth factor II promoted expansion of granulocyte-macrophage colony-forming cells in serum-deprived liquid cultures of human peripheral blood cells. Exp. Hematol. 21:1447.
28. Dainiak, N., and S. Kreczko. 1985. Interactions of insulin, insulin-like growth factor II, and platelet-derived growth factor in erythropoietic culture. J. Clin. Invest. 76:1237.
29. Sander, M., S. Sorha, and N. Dainiak. 1993. Insulin-like growth factors stimulate erythropoiesis in serum-substituted umbilical cord blood cultures. Exp. Hematol. 21:25.
30. Merchav, S., I. Silvian-Drachsler, I. Tatarsky, M. Lake, and A. Skottner. 1992. Comparative studies of erythroid-potentiating effects of biosynthetic human insulin-like growth factors I and II. J. Clin. Endocrinol. Metab. 74:447.
31. Merchav, S., M. Mats, and A. Skottner. 1993. Comparative studies of the granulopoietic enhancing effects of biosynthetic human insulin-like growth factors I and II. J. Cell. Physiol. 157:178.
32. Schwartz, G. N., M. K. Warren, K. Sakano, J. M. Szabo, S. W. Kessler, A. Pashapour, R. E. Gress, and J. F. Perdue. 1996. Comparative effects of insulin-like growth factor II (IGF-II) and IGF-II mutants specilic for IGF-II/CIM6-P or IGF-I receptors on in vitro hematopoiesis. Stem Cells 14:337.
33. Taub, D. D., A. R. Llyod, K. Conlon, J. M. Wang, J. R. Ortaldo, A. Harada, K. Matsushima, D. J. Kelvin, and J. J. Oppenheim. 1993. Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells. J. Exp. Med. 177:1809.
34. Strieter, R. M., P. J. Polverini, S. L. Kunkel, D. A. Arenberg, M. D. Burdick, J. Kasper, J. Dzuiba, J. Van Damme, A. Walz, D. Marriott, S.-Y. Chan, S. Roczniak, and A. B. Shanafelt. 1995. The functional role of the ELR motif in CXC chemokine-mediated angiogenesis. J. Biol. Chem. 270:27348.
35. Angiolillo, A. L., C. Sgadari, D. D. Taub, F. Liao, J. M. Farber, S. Maheshwari, H. K. Kleinman, G. H. Reaman, and G Tosato. 1995. Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo. J. Exp. Med. 182:155.
36. Loetscher, M., B. Gerber, P. Loetscher, S. A. Jones, L. Piali, I. Clark-Lewis, M. Baggiolini, and B. Mose. 1996. Chemokine receptor specific for IP10 and Mig: structure, function, and expression in activated T-lymphocytes. J. Exp. Med. 184:963.
37. O'Reilly, D. R., C. K. Miller, and V. A. Luckow. 1992. Baculovirus Expression Vectors: A Laboratory Manual. W. H. Freeman Company, New York, Chapter 12, p. 124.
38. Worton, R. G., E. A. McCulloch, and J. E. Till. 1969. Physical separation of hemopoietic stem cells from cells forming colonies in culture. J. Cell. Physiol. 74:17.
39. Iscove, N. N. Culture of lymphocytes and hematopoietic cells in serum-free medium. In: Methods for Serum-Free Culture of Neuronal and Lymphoid Cells. 1984. D. W. Barnes, D. A. Sibasku, and G. H. Sato, eds. Liss, New York, p. 169.
40. Migliaccio, G., and A. R. Migliaccio. 1987. Cloning of human erythroid progenitors (BFU-E) in the absence of fetal bovine serum. Br. J. Haematol. 67:129.
41. Sutherland, H. J., C. J. Eaves, P. M. Lansdorp, G. L. Phillips, and D. E. Hogge. 1991. Differential regulation of primitive human hematopoietic cells in long-term cultures maintained on genetically engineered murine stromal cells. Blood 78: 666.
42. Sutherland, H. J., P. M. Lansdorp, D. H. Henkelman, A. C. Eaves, and C. J. Eaves. 1990. Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers. Proc. Natl. Acad. Sci. USA 87:3584.
43. Pettengell, R., T. Luft, R. Henschler, J. M. Hows, T. M. Dexter, D. Ryder, and N. G. Testa. 1994. Direct comparison by limiting dilution analysis of long-term culture-initiating cells in human bone marrow, umbilical cord blood, and blood stem cells. Blood 84:3653.
44. St. Groth, S. F. 1982. The evaluation of limiting dilution assays. J. Immunol. Methods 49:R11.
45. Keller, J. R., M. Ortiz, and F. W. Ruscetti. 1995. Steel factor (c-kit ligand) promotes the survival of hematopoietic stem/progenitor cells in the absence of cell division. Blood 86:1757.
46. + cells in the absence of other growth factors. Exp. Hematol. 21:413.
47. Rubin, R., and R. Baserga. 1995. Biology of disease, insulin-like growth factor-I receptor: its role in cell proliferation, apoptosis, and tumorigenicity. Lab. Invest. 73:311.
48. Jones, J. I., and D. R. Clemmons. 1995. Insulin-like growth factors and their binding proteins: biological actions. Endocr. Rev. 16:3.
49. Kulik G., A. Klippel, and M. J. Weber. 1997. Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Mol. Cell. Biol. 17:1595.
50. 1 cyclin-dependent kinases. Genes Dev. 9:1149.
51. Maione, T. E., G. S. Gray, J Petro, A. J. Hunt, A. L. Donner, S. I Bauer, H. F. Carson, and R. J. Sharpe. 1990. Inhibition of angiogenesis by recombinant human platelet factor-4 and related peptides. Science 247:77.
52. Luster, A. D., S. M. Greenberg, and P. Leder. 1995. The IP-10 chemokine binds to a a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation. J. Exp. Med. 182:219.
53. Witt, D. P., and A. D. Lander. 1994. Differential binding of chemokines to glycosaminoglycan subpopulations. Curr. Biol. 4:94.
54. Jessell, T. M., and D. A. Melton. 1992. Diffusible factors in vertebrate embryonic induction. Cell 68:257.
55. Qinggang, L., R. Blacher, F. Esch, and L. F. Congote. 1990. A heparin-binding erythroid cell stimulating factor from fetal bovine serum has the N-terminal sequence of insulin-like growth factor II. Biochem. Binphys. Res. Commun. 166: 557.
56. De Ceuninck, F., J. Willeput, and M. Corvol. 1995. Purification and characterization of insulin-like growth factor II (IGF II) and an IGF II variant from human placenta. J. Chromatogr. 666:203.