Differential K+ channel clustering activity of PSD-95 and SAP97, two related membrane-associated putative guanylate kinases

Neuropharmacology

Volumn 35, Issue 7, 1996, Pages 993-1000

  Kim, E ^a   Sheng, M ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Membrane cytoskeleton; PDZ domain; Potassium channel; PSD 95; SAP97; Subcellular targeting

Indexed keywords

GUANYLATE CYCLASE; POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CYTOSKELETON; GENE EXPRESSION; GENE LOCATION; MUTATION; NERVE CELL; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN TARGETING; SIGNAL TRANSDUCTION;

EID: 0030002705     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/0028-3908(96)00093-7     Document Type: Article

References (29)

1. + channel. Neuron. 7:1991;471-483.
2. Bartel P.L., Chien C.-T., Sternglanz R. and Fileds S. (1993) Using the 2-hybrid system to detect protein-protein interactions in cellular interactions in development. In: A Practical Approach (Hartley D.A., Ed.), pp. 153-179. Oxford University Press, Oxford.
3. + channels. In: Handbook of Receptors and Channels: Liganda and Voltage-gated Ion Channels (North R.A., Eds), pp. 1-72. CRC Press, Boca Raton.
4. Cho K.-O., Hunt C.A., Kennedy M.B. The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein. Neuron. 9:1992;929-942.
5. Froehner S.C. Regulation of ion channel distribution at synapses. Ann. Rev. Neurosci. 16:1993;347-368.
6. Hollenberg S.M., Sternglanz R., Cheng P.F., Weintraub H. Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Molec. Cell. Biol. 15:1995;3813-3822.
7. Hunt C.A., Schenker L.J., Kennedy M.B. PSD-95 is associated with the postsynaptic density and not with the presynaptic membrane at forebrain synapses. J. Neurosci. 16:1996;1380-1388.
8. Kim E., Cho K.-O., Rothschild A., Sheng M. Heteromultimerization and NMDA receptor clustering activity of chapsyn-110, a novel member of the PSD-95 family of synaptic proteins. Neuron. 17:1996;103-113.
9. + channels by interaction with a family of membrane-associated guanylate kinases. Nature. 378:1995;85-88.
10. Kirsch J., Wolters I., Triller A., Betz H. Gephyrin antisense oligonucleotides prevent glycine receptor clustering in spinal neurons. Nature. 366:1993;745-748.
11. Kistner U., Wenzel B.M., Veh R.W., Cases-Langhoff C., Garner A.M., Appeltauer U., Voss B., Gundelfinger E.D., Garner C.C. SAP90, a rat presynaptic protein related to the product of the Drosophila tumor suppressor gene dlg-A. J. Biol. Chem. 268:1993;4580-4583.
12. Klumpp D.J., Song E.J., Ito S., Sheng M.H., Jan L.Y., Pinto L.H. The Shaker-like potassium channels of the mouse rod bipolar cell and their contributions to the membrane current. J. Neurosci. 15:1995;5004-5013.
13. Kornau H.-C., Schenker L.T., Kennedy M.B., Seeburg P.H. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science. 269:1995;1737-1740.
14. Kuhse J., Betz H., Kirsch J. The inhibitory glycine receptor: architecture, synaptic localization and molecular pathology of a postsynaptic ion-channel complex. Curr. Opin. Neurobiol. 5:1995;318-323.
15. Lahey T., Gorczyca M., Jia X.-X., Budnik V. The Drosophila tumor suppressor gene dlg is required for normal synaptic bouton structure. Neuron. 13:1994;823-835.
16. Lue R.A., Marfatia S.M., Branton D., Chishti A.H. Cloning and characterization of hdlg: The human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1. Proc. Natn. Acad. Sci. U.S.A. 91:1994;9818-9822.
17. + channel polypeptides in rat hippocampal neurons developing in situ and in vitro. J. Neurosci. 15:1995;3840-3851.
18. Meyer G., Kirsch J., Betz H., Langosch D. Identification of a gephyrin binding motif on the glycine receptor β subunit. Neuron. 15:1995;563-572.
19. Müller B.M., Kistner U., Veh R.W., Cases-Langhoff C., Becker B., Gundelfinger E.D., Garner C.C. Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein. J. Neurosci. 15:1995;2354-2366.
20. Niethammer M., Kim E., Sheng M. Interaction between the C-terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases. J. Neurosci. 16:1996;2157-2163.
21. + channel α- and β-subunit polypeptides in rat brain. J. Neurosci. 15:1995;5360-5371.
22. Schwarz T.L., Tempel B.L., Papazian D.M., Jan Y.N., Jan L.Y. Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila. Nature. 331:1988;137-142.
23. Sheng M., Cummings J., Roldan L.A., Jan Y.N., Jan L.Y. Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature. 368:1994;144-147.
24. + channels detected in vivo. Nature. 365:1993;72-75.
25. + channel proteins in rat central neurons. Neuron. 9:1992;271-284.
26. + channel subunit in different neurons of rat brain. J. Neurosci. 14:1994;2408-2417.
27. + channels in terminal and juxtaparanodal regions of neurons. Nature. 365:1993;75-79.
28. Wang H., Kunkel D.D., Schwartzkroin P.A., Tempel B.L. Localization of Kv1.1 and Kv1.2, two K channel proteins, to synaptic terminals, somata, and dendrites in the mouse brain. J. Neurosci. 14:1994;4588-4599.
29. Woods D.F., Bryant P.J. The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions. Cell. 66:1991;451-464.