Role of the EGF receptor pathway in growth and patterning of the Drosophila wing through the regulation of vestigial

Development

Volumn 126, Issue 5, 1999, Pages 975-985

  Nagaraj, Raghavendra ^a   Pickup, Amanda T ^a   Howes, Robert ^b   Moses, Kevin ^c   Freeman, Matthew ^b   Banerjee, Utpal ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

D V boundary; Drosophila; EGFR signaling; Notch signaling; Spitz; Vestigial; Wing

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR;

ANIMAL TISSUE; ARTICLE; DEVELOPMENTAL GENETICS; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO PATTERN FORMATION; FORELIMB; GENE MUTATION; GENETIC TRANSCRIPTION; LIMB DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; REGULATOR GENE;

ANIMALS; BODY PATTERNING; DROSOPHILA; DROSOPHILA PROTEINS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; WING;

ANIMALIA; ARACHNIDA; HEXAPODA;

EID: 0033035606     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (61)

1. Blair, S. S. (1995). Compartments and appendage development in Drosophila. BioEssays 17, 299-309.
2. Blair, S. S. (1994). A role for the segment polarity gene shaggy-zeste white 3 in the specification of regional identity in the developing wing of Drosophila. Dev. Biol. 162, 229-244.
3. Brand, A. H. and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenolypes. Development 118, 401-415.
4. Clifford, R. J. and Schupbach, T. (1989). Coordinately and differentially mutable activities of torpedo, the Drosophila melanogaster homolog of the vertebrate EGF receptor gene. Genetics 123, 771-787.
5. Cohen, B., McGuffin, M. E., Pfeifle, C., Segal, D. and Cohen, S. M. (1992). apterous, a gene required for imaginal disc development in Drosophila encodes a member of the LIM family of developmental regulatory proteins. Genes Dev. 6, 715-729.
6. Cohen, S. M. (1996). Controlling growth of the wing: vestigial integrates signals from the compartment boundaries. BioEssays 18, 855-858.
7. Couso, J. P., Bishop, S. A. and Martinez-Arias, A. (1994). The Wingless signalling pathway and the patterning of the wing margin in Drosophila. Development 120, 621-636.
8. Couso, J. P., Knust, E. and Martinez-Arias, A. (1995). Serrate and Wingless cooperate to induce vestigial gene expression and wing formation in Drosophila. Curr. Biol. 5, 1437-1448.
9. de Celis, J. F., Garcia-Bellido, A. and Bray, S. J. (1996). Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc. Development 122, 359-369.
10. Diaz-Benjumea, F. J. and Cohen, S. M. (1993). Interaction between dorsal and ventral cells in the imaginai disc direct wing development in Drosophila. Cell 75, 741-752.
11. Diaz-Benjumea, F. J. and Cohen, S. M. (1995). Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing. Development 121, 4215-4225.
12. Diaz-Benjumea, F. J. and Garcia-Bellido, A. (1990). Behavior of cells mutant for an EGF receptor homologue of Drosophila in genetic mosaics. Proc. Natl. Acad. Sci. USA 242, 36-44.
13. Diaz-Benjumea, F. J. and Hafen, E. (1994). The sevenless signaling cassette mediates Drosophila EGF receptor function during epidermal development. Development 120, 569-578.
14. Doherty, D., Feger, G., Younger-Shepherd, S., Jan, L. Y. and Jan, Y. N. (1996). Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation. Genes Dev. 10, 421-434.
15. Dominguez, M., Wasserman, J. D. and Freeman, M. (1998). Multiple functions of the EGF receptor in Drosophila eye development. Curr. Biol. 18, 1039-1048.
16. Freeman, M. (1994). The spitz gene is required for photoreceptor determination in the Drosophila eye where it interacts with the EGF receptor. Mech. Dev. 48, 25-32.
17. Freeman, M. (1996). Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye. Cell 87, 651-660.
18. Fleming, R. J., Scottgale, T. N., Diederich, R. J. and Artavanis-Tsakonas, S. (1990). The Serrate gene encodes a putative EGF-like transmembrane protein essential for proper ectodermal development of Drosophila melanogaster. Genes Dev. 4, 2188-2201.
19. Gabay, L., Seger, R. and Shilo, B.-Z. (1997). In situ activation pattern of Drosophila EGF receptor pathway during development. Science 277, 1103-1106.
20. Golembo, M., Raz, E. and Shilo, B.-Z. (1996). The Drosophila embryonic midline is the site of Spitz processing, and induces activation of the EGF receptor in the ventral ectoderm. Development 122, 3363-3370.
21. Jack, J., Dorsett, D., Delotto, Y. and Liu, S. (1991). Expression of the cut locus in the Drosophila wing margin is required for cell type specification and is regulated by a distant enhancer. Development 113, 735-747.
22. Jiang, J. and Struhl, G. (1996). Complementary and mutually exclusive activities of Decapentaplegic and Wingless organize axial patterning during Drosophila leg development. Cell 86, 401-409.
23. Karim, F. D. and Rubin, G. M. (1998). Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues. Development 125, 1-9.
24. Kim, J., Irvine K. D. and Carroll, S. B. (1995). Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing. Cell 82, 795-802.
25. Kim, J., Johnson, K., Chen, H. J., Carroll, S. B. and Laughon, A. (1997). Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic. Nature 388, 304-308.
26. Kim, J., Sebring, A., Esch, J. J., Kraus, M. E., Vorwerk, K., Magee, J. and Carroll, S. B. (1996). Integration of positional signals and regulation of wing formation and identity by Drosophila vestigial gene. Nature 382, 133-138.
27. Klambt, C. (1993). The Drosophila gene pointed encodes two ETS-like proteins which are involved in the development of the midline glial cells. Development 117, 163-176.
28. Kretzschmar, M., Doody, J. and Massague, J. (1997). Opposing BMP and EGF signaling pathways converge on the TGF-beta family mediator Smad1. Nature 389, 618-622.
29. Kumar, J. P., Tio, M., Hsiung, F., Akopyan, S., Gabay, L., Seger, R., Shilo, B.-Z. and Moses, K. (1998). Dissecting the roles of the Drosophila. EGF receptor in eye development and MAP kinase activation. Development 125, 3875-3885
30. Lecuit, T., Brook, W. J., Ng, M., Calleja, M., Sun, H. and Cohen, S. M. (1996). Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing. Nature 381, 387-393.
31. Menne, T. V. and Klambt, C. (1994). The formation of commissures in the Drosophila CNS depends on the midline cells and on the Notch gene. Development 120, 123-133.
32. Micchelli, C. A., Rulifson, E. J., and Blair, S. S. (1997). The function and regulation of cut expression on the wing margin of Drosophila: Notch. Wingless and a dominant negative role for Delta and Serrate. Development 124, 1485-1495.
33. Nellen, D., Burke, R., Struhl, G. and Basler, K. (1996). Direct and long-range action of a DPP morphogen gradient. Cell 85, 357-368
34. Neumann, C. J. and Cohen, S. M. (1997). Long-range action of Wingless organizes the dorsal-ventral axis of the Drosophila wing. Development 124, 871-880.
35. Ng, M., Diaz-Benjumea, F. J., Vincent, J.-P., Wu, J. and Cohen, S. M. (1996). Specification of the wing by localized expression of Wingless protein. Nature 381, 316-318.
36. Niswander, L., Jeffrey, S., Martin, G. R. and Tickle, C. (1994). A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371, 609-612.
37. O'Neill, E. M., Rebay, I., Tjian, R. and Rubin, G. M. (1994). The activities of two Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/MAPK pathway. Cell 78, 137-147.
38. Pai, L. M., Orsulic, S., Bejsovec, A. and Peifer, M. (1997). Negative regulation of Armadillo, a Wingless effector in Drosophila. Development 124, 2255-2266.
39. Panin, V. M., Papayannopoulos, V., Wilson, R. and Irvine, K. D. (1997). Fringe modulates Notch-ligand interactions. Nature 387, 908-912.
40. Perrimon, N. and Perkins, L. A. (1997). There must be 50 ways to rule the signal: the case of the Drosophila EGF receptor. Cell 89, 13-16.
41. Phillips, R. G. and Whittle, J. R. (1993). wingless expression mediates determination of peripheral nervous system elements in late stages of Drosophila wing disc development. Development 118, 427-438.
42. Raz, E. and Shilo B.-Z. (1993). Establishment of ventral cell fates in the Drosophila embryonic ectoderm requires DER, the EGF receptor homolog. Genes Dev. 7, 1937-1948.
43. Rulifson, E. J. and Blair, S. S. (1995). Notch regulates Wingless expression and is not required for reception of the paracrine Wingless signal during wing margin neurogenesis in Drosophila. Development 121, 2813-2824.
44. Rulifson, E. J., Micchelli, C. A., Axelrod, J. D., Perrimon, N. and Blair S. S. (1996). wingless refines its own expression domain on the Drosophila wing margin. Nature 384, 72-74.
45. Schnepp, B., Grumbling, G., Donaldson, T. and Simcox A. (1997). Vein is a novel component in the Drosophila epidermal growth factor receptor pathway with similarity to the neuregulins. Genes Dev. 10, 2302-2313.
46. Schweitzer, R., Shaharabany, M., Seger, R. and Shilo, B.-Z. (1995). Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination. Genes Dev. 9, 1518-1529.
47. Schweitzer, R. and Shilo, B.-Z. (1997). A thousand and one roles for the Drosophila EGF receptor. Trends Genet. 13, 191-196.
48. Shubin, N., Tabin, C. and Carroll, S. B. (1997). Fossils, genes and the evolution of animal limbs. Nature 388, 639-648.
49. Simcox, A. (1997). Differential requirement for EGF-like ligands in Drosophila wing development. Mech. Dev. 62, 41-50.
50. Simcox, A., Grumbling, G., Schnepp, B., Bennington-Mathias, C., Hersperger, E, and Shearn, A. (1996). Molecular, phenotypic, and expression analysis of vein, a gene required for growth of the Drosophila wing disc. Dev. Biol. 177, 475-489.
51. Sturtevant, M. A., Roark, M. and Bier, E. (1993). The Drosophila rhomboid gene mediates the localized formation of wing veins and interacts genetically with the components of the EGF-R signaling pathway. Genes Dev. 5, 961-973.
52. Sturtevant, M. A. and Bier, E. (1995). Analysis of the genetic hierarchy guiding wing vein development in Drosophila. Development 121, 785-801.
53. Thomas, U., Speicher, S. A. and Knust, E. (1991). The Drosophila gene Serrate encodes a EGF-like transmembrane protein with a complex expression pattern in the embryos and wing discs. Development 111, 749-761.
54. Tio, M., Ma, C. and Moses, K. (1994). spitz, a Drosophila homolog of transforming growth factor-alpha, is required in the founding photoreceptor cells of lhe compound eye facets. Mech. Dev. 48, 13-23.
55. Tio, M. and Moses, K. (1997). The Drosophila TGF alpha homolog Spitz acts in photoreceptor recruitment in the developing retina. Development 124, 343-351.
56. Tsuda, L., Inoue, Y. H., Yoo, M. A., Mizuno, M., Hata, M., Lim, Y. M., Adachi-Yamada, T., Ryo, H., Masamune, Y. and Nishida, Y. (1993). A protein kinase similar to MAP kinase activator acts downstream of the raf kinase in Drosophila. Cell 72, 407-414.
57. Wappner, P., Gabay, L. and Shilo, B.-Z. (1997). Interactions between the EGF receptor and DPP pathways establish distinct cell fates in the tracheal placodes. Development 124, 4707-4716.
58. Williams, J. A., Bell, J. B. and Carroll, S. B. (1991). Control of Drosophila wing and haltere development by the nuclear vestigial gene product. Genes Dev. 5, 2481-2495.
59. Williams, J. A., Paddock, S. W., Vorwerk, K. and Carroll, S. B. (1994). Organization of wing formation and induction of a wing-patterning gene at the dorsal/ventral compartment boundary. Nature 368, 299-305.
60. Xu, T. and Rubin, G. M. (1993). Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117, 1223-1237.
61. Zecca, M., Basler, K. and Struhl, G. (1996). Direct and long-range action of a wingless morphogen gradient Cell 87, 833-844.