Enhancer-dependent transcriptional oscillations in mouse erythroleukemia cells

Molecular and Cellular Biology

Volumn 19, Issue 7, 1999, Pages 4907-4917

  Feng, Yong Qing ^a   Alami, Raouf ^a   Bouhassira, Eric E ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE I; RECOMBINASE;

ANIMAL CELL; ARTICLE; CONFORMATION; ERYTHROLEUKEMIA CELL; GENE ACTIVATION; GENE CASSETTE; GENE EXPRESSION; GENE INACTIVATION; GENETIC TRANSCRIPTION; MOLECULAR STABILITY; MOUSE; NONHUMAN; OSCILLATION; PRIORITY JOURNAL;

ANIMALIA;

EID: 0033031226     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.7.4907     Document Type: Article

References (54)

1. Bouhassira, E. E., K. Westerman, and P. Leboulch. 1997. Transcriptional behavior of LCR enhancer elements integrated at the same chromosomal locus by recombinase-mediated cassette exchange. Blood 90:3332-3344.
2. Braunstein, J. D., and C. L. Schildkraut. 1984. The β-major and β-minor globin genes in murine erythroleukemia cells replicate during the same early interval of the S phase. Biochem. Biophys. Res. Commun. 123:108-113.
3. Bungert, J., U. Dave, K. C. Lim, K. H. Lieuw, J. A. Shavit, Q. H. Liu, and J. D. Engel. 1995. Synergistic regulation of human β-globin gene switching by locus control region elements HS3 and HS4. Genes Dev. 9:3083-3096.
4. Chen, W. Y., E. C. Bailey, S. L. McCune, J. Y. Dong, and T. M. Townes. 1997. Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase. Proc. Natl. Acad. Sci. USA 94:5798-5803.
5. Dhar, V., A. Nandi, C. L. Schildkraut, and A. I. Skoultchi. 1990. Erythroid-specific nuclease-hypersensitive sites flanking the human β-globin domain. Mol. Cell. Biol. 10:4324-4333.
6. Epner, E., A. Reik, D. Cimbora, A. Telling, M. A. Bender, S. Fiering, T. Enver, D. I. Martin, M. Kennedy, G. Keller, and M. Groudine. 1998. The β-globin LCR is not necessary for an open chromatin structure or developmentally regulated transcription of the native mouse β-globin locus. Mol. Cell 2:447-455.
7. Feng, Y. Q., J. Seibler, R. Alami, A. Eisen, S. N. Fiering, and E. E. Bouhassira. Site-specific chromosomal integration in mammalian cells: highly efficient CRE recombinase-mediated cassette exchange. Submitted for publication.
8. Fiering, S., E. Epner, K. Robinson, Y. Zhuang, A. Telling, M. Hu, D.I.K. Martin, T. Enver, T. T. Ley, and M. Groudine. 1995. Targeted deletion of 5′HS2 of the murine β-globin LCR reveals that it is not essential for proper regulation of the β-globin locus. Genes Dev. 9:2203-2213.
9. Fiering, S., J. P. Northrop, G. P. Nolan, P. S. Mattila, G. R. Crabtree, and L. A. Herzenberg. 1990. Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor. Genes Dev. 4:1823-1834.
10. Fiering, S. N., M. Roederer, G. P. Nolan, D. R. Micklem, D. R. Parks, and L. A. Herzenberg. 1991. Improved FACS-Gal: flow cytometric analysis and sorting of viable eukaryotic cells expressing reporter gene constructs. Cytometry 12:291-301.
11. Flamigni, F., S. Marmiroli, C. M. Caldarera, and C. Guarnieri. 1989. Effect of sodium arsenite on the induction and turnover of ornithine decarboxylase activity in erythroleukemia cells. Cell Biochem. Funct. 7:213-217.
12. Flamigni, F., S. Marmiroli, C. Guarnieri, and C. M. Caldarera. 1989. Stabilization of ornithine decarboxylase in erythroleukemia cells depleted of ATP. Biochem. Biophys. Res. Commun. 163:1217-1222.
13. Forrester, W. C., E. Epner, M. C. Driscoll, T. Enver, M. Brice, T. Papayannopoulou, and M. Groudine. 1990. A deletion of the human β-globin locus activation region causes a major alteration in chromatin structure and replication across the entire β-globin locus. Genes Dev. 4:1637-1549.
14. Fraser, P., and F. Grosveld. 1998. Locus control regions, chromatin activation and transcription. Curr. Opin. Cell Biol. 10:361-365.
15. Garrick, D., S. Fiering, D.I.K. Martin, and E. Whitelaw. 1998. Repeat-induced gene silencing in mammals. Nat. Genet. 18:56-59.
16. Garrick, D., H. Sutherland, G. Robertson, and E. Whitelaw. 1996. Variegated expression of a globin transgene correlates with chromatin accessibility but not methylation status. Nucleic Acids Res. 24:4902-4909.
17. Gross, D. S., and W. T. Garrard. 1995. Nuclease hypersensitive sites in chromatin. Annu. Rev. Biochem. 57:159-197.
18. Grosveld, F., M. Antoniou, M. Berry, E. De Boer, N. Dillon, J. Ellis, O. Hanscombe, J. Hurst, A. Imam, et al. 1993. The regulation of human globin gene switching. Philos. Trans. R. Soc. Lond. Ser. B 339:183-291. [Review.]
19. Grosveld, F., G. B. van Assendelft, D. R. Greaves, and G. Kollias. 1987. Position-independent, high-level expression of the human β-globin gene in transgenic mice. Cell 51:975-985.
20. Groudine, M., R. Eisenman, R. Gelinas, and H. Weintraub. 1983. Developmental aspects of chromatin structure and gene expression. Prog. Clin. Biol. Res. 134:159-182.
21. Groudine, M., W. C. Forrester, U. Novak, and E. Epner. 1989. Replication and activation of the human β-globin gene domain. Prog. Clin. Biol. Res. 316A:15-35.
22. Groudine, M., T. Kohwi-Shigematsu, R. Gelinas, G. Stamatoyannopoulos, and T. Papayannopoulou. 1983. Human fetal to adult hemoglobin switching: changes in chromatin structure of the β-globin gene locus. Proc. Natl. Acad. Sci. USA 80:7551-7555.
23. Hebbes, T. R., A. L. Clayton, A. W. Thorne, and C. Crane-Robinson. 1994. Core histone hyperacetylation co-maps with generalized DNase I sensitivity in the chicken β-globin chromosomal domain. EMBO J. 13:1823-1830.
24. Henikoff, S. 1992. Position effect and related phenomena. Curr. Opin. Genet. Dev. 2:907-912. (Review.)
25. Hofer, E., and J. E. Darnell, Jr. 1981. The primary transcription unit of the mouse β-major globin gene. Cell 23:585-593.
26. Hug, B. A., R. L. Wesselschmidt, S. Fiering, M. A. Bender, E. Epner, M. Groudine, and T. J. Ley. 1996. Analysis of mice containing a targeted deletion of β-globin locus control region 5′ hypersensitive site 3. Mol. Cell. Biol. 16:2906-2912.
27. Ivanova, E., G. Pironcheva, and L. Djondjurov. 1981. Turnover of the major polypeptides of 40-S monomer particles. Eur. J. Biochem. 113:569-573.
28. Karpen, G. H. 1994. Position-effect variegation and the new biology of heterochromatin. Curr. Opin. Genet. Dev. 4:281-291. (Review.)
29. Kerr, W. G., G. P. Nolan, and L. A. Herzenberg. 1989. In situ detection of transcriptionally active chromatin and genetic regulatory elements in individual viable mammalian cells. Immunology 2(Suppl.):74-78.
30. Khochbin, S., E. Principaud, A. Chabanas, and J. J. Lawrence. 1988. Early events in murine erythroleukemia cells induced to differentiate. Accumulation and gene expression of the transformation-associated cellular protein p53. J. Mol. Biol. 200:55-64.
31. Ko, M. S., H. Nakauchi, and N. Takahashi. 1990. The dose dependence of glucocorticoid-inducible gene expression results from changes in the number of transcriptionally active templates. EMBO J. 9:2835-2842.
32. Krishan, A. 1975. Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining. J. Cell Biol. 66:188-193.
33. Lang, R. B., L. W. Stanton, and K. B. Marcu. 1982. On immunoglobulin heavy chain gene switching: two gamma 2b genes are rearranged via switch sequences in MPC-11 cells but only one is expressed. Nucleic Acids Res. 10:611-630.
34. Martin, D.I.K., S. Fiering, and M. Groudine. 1996. Regulation of β-globin gene expression: straightening out the locus. Curr. Opin. Genet. Dev. 6:488-495.
35. Milot, E., J. Strouboulis, T. Trimborn, M. Wijgerde, E. Deboer, A. Langeveld, K. TanUn, W. Vergeer, N. Yannoutsos, F. Grosveld, and P. Fraser. 1996. Heterochromatin effects on the frequency and duration of LCR-mediated gene transcription. Cell 87:105-114.
36. Newlands, S., L. K. Levitt, C. S. Robinson, A. B. Karpf, V. R. Hodgson, R. P. Wade, and E. C. Hardeman. 1998. Transcription occurs in pulses in muscle fibers. Genes Dev. 12:2748-2758.
37. Ogawa, M. 1993. Differentiation and proliferation of hematopoietic stem cells. Blood 81:2844-2853.
38. Peterson, K. R., C. H. Clegg, P. A. Navas, E. J. Norton, T. G. Kimbrough, and G. Stamatoyannopoulos. 1996. Effect of deletion of 5′HS3 or 5′HS2 of the human β-globin locus control region on the developmental regulation of globin gene expression in β-globin locus yeast artificial chromosome transgenic mice. Proc. Natl. Acad. Sci. USA 93:6605-6609.
39. Reddy, S., J. V. DeGregori, H. von Melchner, and H. E. Ruley. 1991. Retrovirus promoter-trap vector to induce lacZ gene fusions in mammalian cells. J. Virol. 65:1507-1515.
40. Reik, A., A. Telling, G. Zitnik, D. Cimbora, E. Epner, and M. Groudine. 1998. The locus control region is necessary for gene expression in the human β-globin locus but not the maintenance of an open chromatin structure in erythroid cells. Mol. Cell. Biol. 18:5992-6000.
41. Robertson, G., D. Garrick, M. Wilson, D.I.K. Martin, and E. Whitelaw. 1996. Age-dependent silencing of globin transgenes in the mouse. Nucleic Acids Res. 24:1465-1471.
42. Rousseau, D., S. Khochbin, C. Gorka, and J. J. Lawrence. 1991. Regulation of histone H1(0) accumulation during induced differentiation of murine erythroleukemia cells. J. Mol. Biol. 217:85-92.
43. Sadelain, M. 1997. Genetic treatment of the haemoglinopathies: recombinations and new combinations. Br. J. Haemat. 98:247-253.
44. Stamatoyannopoulos, G., and A. W. Nienhius. 1994. Hemoglobin switching, p. 107-156. In G. Stamatoyanoupoulos (ed.), The molecular basis of blood diseases. W. B. Saunders, Philadelphia, Pa.
45. Struhl, K. 1998. Histone acetylation and transcriptional regulatory mechanisms, Genes Dev. 12:599-606.
46. Suda, T., J. Suda, and M. Ogawa. 1983. Single-cell origin of mouse hematopoietic colonies expressing multiple lineages in variable combinations. Proc. Natl. Acad. Sci. USA 80:6689-6693.
47. Sutherland, H.G.E., D.I.K. Martin, and E. Whitelaw. 1997. A globin enhancer acts by increasing the proportion of erythrocytes expressing a linked transgene. Mol. Cell. Biol. 17:1607-1614.
48. Tuan, D., W. Solomon, Q. Li, and I. M. London. 1985. The "β-like-globin" gene domain in human erythroid cells. Proc. Natl. Acad. Sci. USA 82:6384-6388.
49. Walters, M. C., S. Fiering, J. Eidemiller, W. Magis, M. Groudine, and D.I.K. Martin. 1995. Enhancers increase the probability but not the level of gene expression. Proc. Natl. Acad. Sci. USA 92:7125-7129.
50. Walters, M. C., W. Magis, S. Fiering, J. Eidemiller, D. Scalzo, M. Groudine, and D.I.K. Martin. 1996. Transcriptional enhancers act in cis to suppress position-effect variegation. Genes Dev. 10:185-195.
51. Weiler, K. S., and B. T. Wakimoto. 1995. Heterochromatin and gene expression in Drosophila. Annu. Rev. Genet. 29:577-605.
52. Yoshida, M., S. Horinouchi, and T. Beppu. 1995. Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function. Bioessays 17:423-430.
53. Yoshida, M., M. Kijima, M. Akita, and T. Beppu. 1990. Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A. J. Antibiot. 265:17174-17179.
54. Yoshida, M., S. Nomura, and T. Beppu. 1987. Effects of trichostatins on differentiation of murine erythroleukemia cells. Cancer Res. 47:3688-3691.