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Volumn 17, Issue 3, 1997, Pages 1607-1614

A globin enhancer acts by increasing the proportion of erythrocytes expressing a linked transgene

Author keywords

[No Author keywords available]

Indexed keywords

GLOBIN;

EID: 0031018481     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.3.1607     Document Type: Article
Times cited : (65)

References (54)
  • 1
    • 0028260976 scopus 로고
    • Overcoming telomeric silencing a trans-activator competes to establish gene expression in a cell cycle-dependent way
    • Aparicio, O. M., and D. E. Gottschling. 1994. Overcoming telomeric silencing a trans-activator competes to establish gene expression in a cell cycle-dependent way. Genes Dev. 8:1133-1146.
    • (1994) Genes Dev. , vol.8 , pp. 1133-1146
    • Aparicio, O.M.1    Gottschling, D.E.2
  • 2
    • 0023118991 scopus 로고
    • Macromolecular synthesis and degradation during terminal erythroid cell development
    • Bonanou-Tzedaki, S. A., and H. R. V. Arnstein. 1987. Macromolecular synthesis and degradation during terminal erythroid cell development. Biomed. Biochim. Acta 46:121-149.
    • (1987) Biomed. Biochim. Acta , vol.46 , pp. 121-149
    • Bonanou-Tzedaki, S.A.1    Arnstein, H.R.V.2
  • 3
    • 0025954630 scopus 로고
    • Clonal coat variation due to a transforming gene expressed in melanocytes of transgenic mice
    • Bradl, M., L. Larue, and B. Mintz. 1991. Clonal coat variation due to a transforming gene expressed in melanocytes of transgenic mice. Proc. Natl. Acad. Sci. USA 88:6447-6451.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 6447-6451
    • Bradl, M.1    Larue, L.2    Mintz, B.3
  • 4
    • 0024281345 scopus 로고
    • DNA methylation and gene activity
    • Cedar, H. 1988. DNA methylation and gene activity. Cell 53:3-4.
    • (1988) Cell , vol.53 , pp. 3-4
    • Cedar, H.1
  • 5
    • 85035184581 scopus 로고    scopus 로고
    • Do transgene arrays form heterochromatin in vertebrates?
    • in press
    • Dorer, D. Do transgene arrays form heterochromatin in vertebrates? Transgene Res., in press.
    • Transgene Res.
    • Dorer, D.1
  • 6
    • 0028286165 scopus 로고
    • Expansions of transgene repeat cause heterochromatin formation and gene silencing in Drosophila
    • Dorer, D. R., and S. Henikoff. 1994. Expansions of transgene repeat cause heterochromatin formation and gene silencing in Drosophila. Cell 77:993-1002.
    • (1994) Cell , vol.77 , pp. 993-1002
    • Dorer, D.R.1    Henikoff, S.2
  • 7
    • 0028847640 scopus 로고
    • Random activation of a transgene under the control of a hybrid hCD2 locus control region/Ig enhancer regulatory element
    • Elliot, J. I., R. Festenstein, M. Tolaini, and D. Kioussis. 1995. Random activation of a transgene under the control of a hybrid hCD2 locus control region/Ig enhancer regulatory element. EMBO J. 14:575-584.
    • (1995) EMBO J. , vol.14 , pp. 575-584
    • Elliot, J.I.1    Festenstein, R.2    Tolaini, M.3    Kioussis, D.4
  • 8
    • 0024447249 scopus 로고
    • The human β-globin locus activation region alters the development fate of a human fetal globin gene in transgenic mice
    • Enver, T., A. J. Ebens, W. C. Forrester, and G. Stamatoyannopoulos. 1989. The human β-globin locus activation region alters the development fate of a human fetal globin gene in transgenic mice. Proc. Natl. Acad. Sci. USA 86:7033-7037.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 7033-7037
    • Enver, T.1    Ebens, A.J.2    Forrester, W.C.3    Stamatoyannopoulos, G.4
  • 11
    • 0023663887 scopus 로고
    • Position-independent, high-level expression of the human β-globin gene in transgenic mice
    • Grosveld, F., G. Blom van Assendelft, D. R. Greaves, and G. Kollias. 1987. Position-independent, high-level expression of the human β-globin gene in transgenic mice. Cell 51:975-985.
    • (1987) Cell , vol.51 , pp. 975-985
    • Grosveld, F.1    Blom Van Assendelft, G.2    Greaves, D.R.3    Kollias, G.4
  • 12
    • 0024747815 scopus 로고
    • High-level, erythroid-specific expression of the human α-globin gene in transgenic mice and the production of human hemoglobin in murine erythrocytes
    • Hanscombe, O., M. Vidal, J. Kaeda, L. Luzzatto, D. R. Greaves, and F. Grosveld. 1989. High-level, erythroid-specific expression of the human α-globin gene in transgenic mice and the production of human hemoglobin in murine erythrocytes. Genes Dev. 3:1572-1581.
    • (1989) Genes Dev. , vol.3 , pp. 1572-1581
    • Hanscombe, O.1    Vidal, M.2    Kaeda, J.3    Luzzatto, L.4    Greaves, D.R.5    Grosveld, F.6
  • 14
    • 0027014049 scopus 로고
    • Position effect and related phenomena
    • Henikoff, S. 1992. Position effect and related phenomena. Curr. Opin. Genet. Dev. 2:907-912.
    • (1992) Curr. Opin. Genet. Dev. , vol.2 , pp. 907-912
    • Henikoff, S.1
  • 15
    • 0021749262 scopus 로고
    • Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma
    • Herbomel, P., B. Bourachot, and M. Yaniv. 1984. Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma. Cell 39:653-662.
    • (1984) Cell , vol.39 , pp. 653-662
    • Herbomel, P.1    Bourachot, B.2    Yaniv, M.3
  • 16
    • 0024993211 scopus 로고
    • A major positive regulatory region located far upstream of the human α-globin gene locus
    • Higgs, D. R., W. G. Wood, A. P. Jarman, J. Sharpe, J. Lida, I.-M. Pretorius, and H. Ayyub. 1990. A major positive regulatory region located far upstream of the human α-globin gene locus. Genes Dev. 4:1588-1601.
    • (1990) Genes Dev. , vol.4 , pp. 1588-1601
    • Higgs, D.R.1    Wood, W.G.2    Jarman, A.P.3    Sharpe, J.4    Lida, J.5    Pretorius, I.-M.6    Ayyub, H.7
  • 17
    • 0025734604 scopus 로고
    • Characterization of the major regulatory element upstream of the human α-globin gene cluster
    • Jarman, A. P., W. G. Wood, J. A. Sharpe, G. Gourdon, H. Ayyub, and D. R. Higgs. 1991. Characterization of the major regulatory element upstream of the human α-globin gene cluster. Mol. Cell. Biol. 11:4679-4689.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4679-4689
    • Jarman, A.P.1    Wood, W.G.2    Sharpe, J.A.3    Gourdon, G.4    Ayyub, H.5    Higgs, D.R.6
  • 18
    • 0023770931 scopus 로고
    • Conversion of normal behavior to shivercr by myelin basic protein antisense cDNA in transgenic mice
    • Katsuki, M., M. Sato, M. Kimura, M. Yokoyama, K. Kobayashi, and T. Nomura. 1988. Conversion of normal behavior to shivercr by myelin basic protein antisense cDNA in transgenic mice. Science 241:593-595.
    • (1988) Science , vol.241 , pp. 593-595
    • Katsuki, M.1    Sato, M.2    Kimura, M.3    Yokoyama, M.4    Kobayashi, K.5    Nomura, T.6
  • 19
    • 0004208863 scopus 로고
    • Oxford University Press, New York, N.Y.
    • Lewin, B. 1990. Genes IV. Oxford University Press, New York, N.Y.
    • (1990) Genes IV
    • Lewin, B.1
  • 20
    • 0025634029 scopus 로고
    • Inactivation of human α-globin gene expression by a de novo deletion located upstream of the α-globin gene cluster
    • Liebhaber, S. A., E.-U. Griese, I. Weiss, F. E. Cash, H. Ayyub, D. R. Higgs, and J. Horst. 1990. Inactivation of human α-globin gene expression by a de novo deletion located upstream of the α-globin gene cluster. Proc. Natl. Acad. Sci. USA 87:9431-9435.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9431-9435
    • Liebhaber, S.A.1    Griese, E.-U.2    Weiss, I.3    Cash, F.E.4    Ayyub, H.5    Higgs, D.R.6    Horst, J.7
  • 21
    • 0030298416 scopus 로고    scopus 로고
    • The vagaries of variegating transgenes
    • Martin, D. I. K., and E. Whitelaw. 1996. The vagaries of variegating transgenes. BioEssays 18:919-923.
    • (1996) BioEssays , vol.18 , pp. 919-923
    • Martin, D.I.K.1    Whitelaw, E.2
  • 22
    • 0026004634 scopus 로고
    • Mosaic expression of a tyrosinase fusion gene in albino mice yields a heritable striped coal color pattern in transgene homozygotes
    • Mintz, B., and M. Bradl. 1991. Mosaic expression of a tyrosinase fusion gene in albino mice yields a heritable striped coal color pattern in transgene homozygotes. Proc. Natl. Acad. Sci. USA 88:9643-9647.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 9643-9647
    • Mintz, B.1    Bradl, M.2
  • 23
    • 11944256454 scopus 로고
    • Conservation of the primary structure, organization, and function of the human and mouse β-globin locus-activation regions
    • Moon, A. M., and T. J. Ley. 1990. Conservation of the primary structure, organization, and function of the human and mouse β-globin locus-activation regions. Proc. Natl. Acad. Sci. USA 87:7693-7697.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 7693-7697
    • Moon, A.M.1    Ley, T.J.2
  • 24
    • 0019769520 scopus 로고
    • The SV40 72 base pair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants
    • Moreau, P., R. Hen, B. Wasylyk, R. Everett, M. P. Gaub, and P. Chambon. 1981. The SV40 72 base pair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants. Nucleic Acids Res. 9:6047-6068.
    • (1981) Nucleic Acids Res. , vol.9 , pp. 6047-6068
    • Moreau, P.1    Hen, R.2    Wasylyk, B.3    Everett, R.4    Gaub, M.P.5    Chambon, P.6
  • 25
    • 0026742198 scopus 로고
    • A single β-globin locus control region element (5′ hypersensitive site 2) is sufficient for developmental regulation of human globin genes in transgenic mice
    • Morley, B. J., C. A. Abbott, J. A. Sharpe, J. Lida, P. S. Chan-Thomas, and W. G. Wood. 1992. A single β-globin locus control region element (5′ hypersensitive site 2) is sufficient for developmental regulation of human globin genes in transgenic mice. Mol. Cell. Biol. 12:2057-2066.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2057-2066
    • Morley, B.J.1    Abbott, C.A.2    Sharpe, J.A.3    Lida, J.4    Chan-Thomas, P.S.5    Wood, W.G.6
  • 26
  • 27
    • 0027182948 scopus 로고
    • Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice
    • Palmiter, R. D., E. P. Sandgren, D. M. Koeller, and R. L. Brinster. 1993. Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice. Mol. Cell. Biol. 13:5266-5275.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 5266-5275
    • Palmiter, R.D.1    Sandgren, E.P.2    Koeller, D.M.3    Brinster, R.L.4
  • 28
    • 0028485216 scopus 로고
    • White gene expression, repressive chromatin domains and homeotic regulation in Drosophila
    • Pirrotta, V., and L. Rastelli. 1994. White gene expression, repressive chromatin domains and homeotic regulation in Drosophila. BioEssays 16:549-556.
    • (1994) BioEssays , vol.16 , pp. 549-556
    • Pirrotta, V.1    Rastelli, L.2
  • 29
    • 0026558933 scopus 로고
    • The LCR-like α-globin positive regulatory element functions as an enhancer in transiently transfected cells during erythroid differentiation
    • Pondel, M., M. George, and N. J. Proudfoot. 1992. The LCR-like α-globin positive regulatory element functions as an enhancer in transiently transfected cells during erythroid differentiation. Nucleic Acids Res. 20:237-243.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 237-243
    • Pondel, M.1    George, M.2    Proudfoot, N.J.3
  • 30
    • 0028430999 scopus 로고
    • Mosaic expression of an HPRT transgene integrated in a region of Y heterochromatin
    • Pravtcheva, D. D., T. L. Wise, N. J. Ensor, and F. J. Ruddle. 1994. Mosaic expression of an HPRT transgene integrated in a region of Y heterochromatin. J. Exp. Zool. 268:452-468.
    • (1994) J. Exp. Zool. , vol.268 , pp. 452-468
    • Pravtcheva, D.D.1    Wise, T.L.2    Ensor, N.J.3    Ruddle, F.J.4
  • 31
    • 0025598196 scopus 로고
    • A enhancer/locus control region is not sufficient to open chromatin
    • Reitman, M., E. Lee, H. Westphal, and G. Felsenfeld. 1990. A enhancer/locus control region is not sufficient to open chromatin. Nature 348:749-752.
    • (1990) Nature , vol.348 , pp. 749-752
    • Reitman, M.1    Lee, E.2    Westphal, H.3    Felsenfeld, G.4
  • 32
    • 0027402585 scopus 로고
    • The major regulatory element upstream of the α-globin gene has classical enhancer and inducible enhancer activity
    • Ren, S., X.-N. Luo, and G. F. Atweh. 1993. The major regulatory element upstream of the α-globin gene has classical enhancer and inducible enhancer activity. Blood 4:1058-1066.
    • (1993) Blood , vol.4 , pp. 1058-1066
    • Ren, S.1    Luo, X.-N.2    Atweh, G.F.3
  • 35
    • 0026042157 scopus 로고
    • α-Thalassemia resulting from deletion of regulatory sequences far upstream of the α-globin structural genes
    • Romao, L., L. Osorio-Almeida, D. R. Higgs, J. Lavinha, and S. A. Leibhaber. 1991. α-Thalassemia resulting from deletion of regulatory sequences far upstream of the α-globin structural genes. Blood 78:1589-1595.
    • (1991) Blood , vol.78 , pp. 1589-1595
    • Romao, L.1    Osorio-Almeida, L.2    Higgs, D.R.3    Lavinha, J.4    Leibhaber, S.A.5
  • 37
    • 0030044430 scopus 로고    scopus 로고
    • Copy number and orientation determine the susceptibility of a gene to silencing by nearby heterochromatin in Drosophila
    • Sabl, J. F., and S. Henikoff. 1996. Copy number and orientation determine the susceptibility of a gene to silencing by nearby heterochromatin in Drosophila. Genetics 142:447-458.
    • (1996) Genetics , vol.142 , pp. 447-458
    • Sabl, J.F.1    Henikoff, S.2
  • 38
    • 0027464687 scopus 로고
    • A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice
    • Schedl, A., L. Montoliu, G. Kelsey, and G. Schutz. 1993. A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice. Nature 362:258-261.
    • (1993) Nature , vol.362 , pp. 258-261
    • Schedl, A.1    Montoliu, L.2    Kelsey, G.3    Schutz, G.4
  • 39
    • 0026494778 scopus 로고
    • Analysis of the human α globin upstream regulatory element (HS-40) in transgenic mice
    • Sharpe, J. A., P. S. Chan-Thomas, J. Lida, H. Ayyub, W. G. Wood, and D. R. Higgs. 1992. Analysis of the human α globin upstream regulatory element (HS-40) in transgenic mice. EMBO J. 11:4565-4572.
    • (1992) EMBO J. , vol.11 , pp. 4565-4572
    • Sharpe, J.A.1    Chan-Thomas, P.S.2    Lida, J.3    Ayyub, H.4    Wood, W.G.5    Higgs, D.R.6
  • 41
    • 0027283593 scopus 로고
    • Role of upstream DNase I hypersensitive sites in the regulation of human α globin gene expression
    • Sharpe, J. A., R. J. Summerhill, P. Vyas, G. Gourdon, D. R. Higgs, and W. G. Wood. 1993. Role of upstream DNase I hypersensitive sites in the regulation of human α globin gene expression. Blood 82:1666-1671.
    • (1993) Blood , vol.82 , pp. 1666-1671
    • Sharpe, J.A.1    Summerhill, R.J.2    Vyas, P.3    Gourdon, G.4    Higgs, D.R.5    Wood, W.G.6
  • 42
    • 0004164996 scopus 로고
    • University Science Books, Mill Valley, Calif.
    • Singer, M., and P. Berg. 1991. Genes and genomes. University Science Books, Mill Valley, Calif.
    • (1991) Genes and Genomes
    • Singer, M.1    Berg, P.2
  • 43
    • 0027367941 scopus 로고
    • Developmental regulation of human γ-globin genes in transgenic mice
    • Stamatoyannopoulos, G., B. Josephson, J.-W. Zhang, and Q. Li. 1993. Developmental regulation of human γ-globin genes in transgenic mice. Mol. Cell. Biol. 13:7636-7644.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7636-7644
    • Stamatoyannopoulos, G.1    Josephson, B.2    Zhang, J.-W.3    Li, Q.4
  • 44
    • 0002398438 scopus 로고
    • Hemoglobin switching
    • G. Stamatoyannopoulos (ed.), W. B. Saunders, Philadelphia, Pa.
    • Stamatoyannopoulos, G., and A. Nienhuis. 1994. Hemoglobin switching, p. 107-156. In G. Stamatoyannopoulos (ed.), The molecular basis of blood diseases. W. B. Saunders, Philadelphia, Pa.
    • (1994) The Molecular Basis of Blood Diseases , pp. 107-156
    • Stamatoyannopoulos, G.1    Nienhuis, A.2
  • 45
    • 0026725369 scopus 로고
    • In vivo footprinting of the human α-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction
    • Strauss, E. C., N. C. Andrews, D. R. Higgs, and S. H. Orkin. 1992. In vivo footprinting of the human α-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction. Mol. Cell. Biol. 12:2135-2142.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2135-2142
    • Strauss, E.C.1    Andrews, N.C.2    Higgs, D.R.3    Orkin, S.H.4
  • 46
    • 85035183328 scopus 로고    scopus 로고
    • Sutherland, H. G. E., and E. Whitelaw. Unpublished observations
    • Sutherland, H. G. E., and E. Whitelaw. Unpublished observations.
  • 47
    • 0028519068 scopus 로고
    • Position effect variegation in yeast
    • Tartof, K. D. 1994. Position effect variegation in yeast. BioEssays 16:713-714.
    • (1994) BioEssays , vol.16 , pp. 713-714
    • Tartof, K.D.1
  • 48
    • 0021876209 scopus 로고
    • Simian virus 40 enhancer increases number of RNA polymerase II molecules on linked DNA
    • Treisman, R., and T. Maniatis. 1985. Simian virus 40 enhancer increases number of RNA polymerase II molecules on linked DNA. Nature 315:72-75.
    • (1985) Nature , vol.315 , pp. 72-75
    • Treisman, R.1    Maniatis, T.2
  • 49
    • 0026747665 scopus 로고
    • Cis-acting sequences regulating expression of the human α-globin cluster lie within constitutively open chromatin
    • Vyas, P., M. A. Vickers, D. L. Simmons, H. Ayyub, C. F. Craddock, and D. R. Higgs. 1992. Cis-acting sequences regulating expression of the human α-globin cluster lie within constitutively open chromatin. Cell 69:781-793.
    • (1992) Cell , vol.69 , pp. 781-793
    • Vyas, P.1    Vickers, M.A.2    Simmons, D.L.3    Ayyub, H.4    Craddock, C.F.5    Higgs, D.R.6
  • 52
    • 0021876210 scopus 로고
    • Simian virus 40 enhancer increases RNA polymerase density within the linked gene
    • Weber, F., and W. Schaffner. 1985. Simian virus 40 enhancer increases RNA polymerase density within the linked gene. Nature 315:75-77.
    • (1985) Nature , vol.315 , pp. 75-77
    • Weber, F.1    Schaffner, W.2
  • 53
    • 0006281492 scopus 로고
    • Formation of stable transcription complexes as assayed by analysis of individual templates
    • Weintraub, H. 1988. Formation of stable transcription complexes as assayed by analysis of individual templates. Proc. Natl. Acad. Sci. USA 85:5819-5823.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 5819-5823
    • Weintraub, H.1
  • 54
    • 85035187108 scopus 로고    scopus 로고
    • Whitelaw, E. Unpublished observations
    • Whitelaw, E. Unpublished observations.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.