Absence of PTEN germ-line mutations in men with a potential inherited predisposition to prostate cancer

Clinical Cancer Research

Volumn 5, Issue 6, 1999, Pages 1387-1391

  Cooney, Kathleen A ^a,b,e   Tsou, Hui C ^c   Petty, Elizabeth M ^a   Miesfeldt, Susan ^d   Ping, Xiao Li ^c   Gruener, Alexandra C ^c   Peacocke, Monica ^c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Columbia University ^*  (United States)

^d UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^e 7310 CCGC ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER LOCALIZATION; CANCER RISK; CANCER SUSCEPTIBILITY; CHROMOSOME 10Q; CLINICAL ARTICLE; COWDEN SYNDROME; FAMILIAL CANCER; HETEROZYGOSITY LOSS; HUMAN; KIDNEY CANCER; MALE; MUTATION; PRIORITY JOURNAL; PROSTATE CANCER; SEQUENCE ANALYSIS; THYROID CANCER; TUMOR SUPPRESSOR GENE;

ADULT; AGED; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GERM-LINE MUTATION; HUMANS; MALE; MIDDLE AGED; NEOPLASMS, SECOND PRIMARY; PHOSPHORIC MONOESTER HYDROLASES; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PROSTATIC NEOPLASMS; PTEN PHOSPHOHYDROLASE; TUMOR SUPPRESSOR PROTEINS;

EID: 0033012720     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Smith, J. R., Freije, D., Carpten, J. D., Gronberg, H., Xu, J., Isaacs, S. D., Brownstein, M. J., Bova, G. S., Guo, H., Bujnovszky, P., Nusskern, D. R., Damber, J-E., Bergh, A., Emanuelsson, M., Kallioniemi, O. P., Walker-Daniels, J., Bailey-Wilson, J. E., Beaty, T. H., Meyers, D. A., Walsh, P. C., Collins, F. S., Trent, J. M., and Isaacs, W. B. Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search. Science (Washington DC), 274: 1371-1374, 1996.
2. Cooney, K. A., McCarthy, J. D., Lange, E., Huang, L., Miesfeldt, S., Montie, J. M., Oesterling, J. E., Sandler, H. M., and Lange, K. Prostate cancer susceptibility locus on chromosome 1q: a confirmatory study. J. Natl. Cancer Inst. (Bethesda), 89: 955-959, 1997.
3. Hsieh, C. L., Oakley-Girvin, I., Gallagher, R. P., Wu, A. W., Kolonel, E. N., Teh, C. Z., Halpern, J., West, D. W., Paffenbarger, R. S., and Whittemore, A. S. Re: Prostate cancer susceptibility locus on chromosome 1q: a confirmatory study. J. Natl. Cancer Inst. (Bethesda), 89: 1983-1984, 1997.
4. Berthon, P., Valeri, A., Cohen-Akenine, A., Drelon, E., Paiss, T., Wohr, G., Latil, A., Millasseau, P., Mellah, I., Cohen, N., Blanche, H., Bellane-Chamtelot, C., Demenais, F., Teillac, P., Le Duc, A., de Petriconi, R., Hautmann, R., Chumakov, I., Bachner, L., Maitland, N. J., Lidereau, R., Vogel, W., Fournier, G., Mangin, P., Cohen, D., and Cussenot, O. Predisposing gene for early-onset prostate cancer, localized on chromosome 1q42.2-43. Am. J. Hum. Genet., 62: 1416-1424, 1998.
5. Xu, J., Meyers, D. A., Freije, D., Isaacs, S. D., Wiley, K., Nusskern, D., Ewing, C. M., Wilkens, E., Bujnovszky, P., Bova, G-S., Walsh, P., Isaacs, W. B., Schleutler, J., Matikainen, M., Tammela, T., Visakorpi, T., Kallioniemi, O-P., Berry, R., Schaid, D., French, A., McDonnell, S., Schroeder, J., Blute, M., Thibodeau, S., Gronberg, H., Emanuelsson, M., Damber, J-E., Bergh, A., Jonsson, A., Smith, J., Bailey-Wilson, J. E., Carpten, J. D., Stephan, D., Gillanders, E., Admudson, I., Kainu, T., Freas-Lutz, D., Baffoe-Bonnie, A., Van Aucken, A., Sood, R., Collins, F., Brownstein, M. J., and Trent, J. Evidence for a prostate cancer susceptibility locus on the X chromosome. Nat. Genet., 20: 175-179, 1998.
6. Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R., Bigner, S. H., Giovanella, B. C., Ittmann, M., Tycko, B., Hibshoosh, H., Wigler, M. H., and Parsons, R. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science (Washington DC), 275: 1943-1947, 1997.
7. Steck, P. A., Pershouse, M. A., Jasser, S. A., Yung, W. K., Lin, H., Ligon, A. H., Langford, L. A., Baumgard, M. L., Hattier, T., Davis, T., Frye, C., Hu, R., Swedlund, B., Teng, D. H., and Tavtigian, S. V. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat. Genet., 15: 356-362, 1997.
8. Liaw, D., Marsh, D. J., Li, J., Dahia, P. L., Wang, S. I., Zheng, Z., Bose, S., Call, K. M., Tsou, H. C., Peacocke, M., Eng, C., and Parsons, R. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat. Genet., 16: 64-67, 1997.
9. Cairns, P., Okami, K., Halachmi, S., Halachmi, N., Esteller, M., Herman, J. G., Jen, J., Isaacs, W. B., Bova, S. G., and Sidransky, D. Frequent inactivation of PTEN/MMAC1 in primary prostate cancer. Cancer Res., 57: 4997-5000, 1997.
10. Facher, E. A., and Law, J. C. PTEN and prostate cancer. J. Med. Genet., 35: 790-790, 1998.
11. Wang, S., Parsons, R., and Ittmann, M. Homozygous deletion of the PTEN tumor suppressor gene in a subset of prostate adenocarcinomas. Clin. Cancer Res., 4: 811-815, 1998.
12. Vlietstra, R., vanAlewijk, D., Hermans, K., vanSteenbrugge, G., and Trapman, J. Frequent inactivation of PTEN in prostate cancer cell lines and xenografts. Cancer Res., 58: 2720-2723, 1998.
13. Pesche, S., Latil, A., Muzeau, F., Cussenot, O., Fournier, G., Longy, M., Eng, C., and Lidereau, R. PTEN/MMAC1/TEP1 involvement in primary prostate cancers. Oncogene, 16: 2879-2883, 1998.
14. Feilotter, H., Nagai, M., Boag, A., Eng, C., and Mulligan, L. Analysis of PTEN and the 10q23 region in primary prostate carcinomas. Oncogene, 16: 1743-1748, 1998.
15. Carter, B. S., Bova, G. S., Beaty, T. H., Steinberg, G. D., Childs, B., Isaacs, W. B., and Walsh, P. C. Hereditary prostate cancer: epidemiologic and clinical features. J. Urol., 150: 797-802, 1993.
16. Bastacky, S. I., Wojno, K. J., Walsh, P. C., Carmichael, M. J., and Epstein, J. I. Prostate cancer: pathological features of hereditary prostate cancer. J. Urol., 153: 987-992, 1995.
17. Parker, S. L., Tong, T., Bolden, S., and Wingo, P. A. Cancer statistics, 1997. CA Cancer J. Clin., 47: 5-27, 1997.
18. DiCristofano, A., Pesce, B., Cordon-Cardo, C., and Pandolfi, P. Pten is essential for embryonic development and tumour suppression. Nat. Genet., 19: 348-355, 1998.
19. Gray, I. C., Phillips, S. M. A., Lee, S. J., Neoptolemos, J. P., Weissenbach, J., and Spurr, N. K. Loss of the chromosomal region 10q23-25 in prostate cancer. Cancer Res., 55: 4800-4803, 1995.
20. Trybus, T. M., Burgess, A. C., Wojno, K. J., Glover, T. W., and Macoska, J. A. Distinct areas of allelic loss on chromosomal regions 10p and 10q in human prostate cancer. Cancer Res., 56: 2263-2267, 1996.
21. Eagle, L. R., Yin, X., Brothman, A. R., Williams, B. J., Atkin, N. B., and Prochownik, E. V. Mutation of the MXI1 gene in prostate cancer. Nat. Genet., 9: 249-255, 1995.
22. Kuczyk, M. A., Serth, J., Bokerneyer, C., Schwede, J., Herrmann, R., Machtens, S., Grunewald, V., Hofner, K., and Jonas, U. The MXI1 tumor suppressor gene is not mutated in primary prostate cancer. Oncol. Rep., 5: 213-216, 1998.
23. Kawamata, N., Park, D., Wilczynski, S., Yokota, J., and Koeffler, H. P. Point mutations of the MXI1 gene are rare in prostate cancers. Prostate, 29: 191-193, 1996.
24. Dahia, P., Marsh, D., Zheng, Z., Zedenius, J., Komminoth, P., Frisk, T., Wallin, G., Parsons, R., Longy, M., Larsson, C., and Eng, C. Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors. Cancer Res., 57: 4710-4713, 1997.
25. Rhei, E., Kang, L., Bogomolniy, F., Federici, M., Borgen, P., and Boyd, J. Mutation analysis of the putative tumor suppressor gene PTEN/ MMAC1 in primary breast carcinomas. Cancer Res., 57: 3657-3659, 1997.
26. Wang, S., Puc, J., Li, J., Bruce, J., Cairns, P., Sidransky, D., and Parsons, R. Somatic mutations of PTEN in glioblastoma multiforme. Cancer Res., 57: 4183-4186, 1997.
27. Rasheed, B., Stenzel, T., McLendon, R., Parsons, R., Friedman, A., Friedman, H., Bigner, D., and Bigner, S. PTEN gene mutations are seen in high-grade but not in low-grade gliomas. Cancer Res., 57: 4187-4190, 1997.
28. Risinger, J., Hayes, A., Berchuck, A., and Barrett, J. PTEN/MMAC1 mutations in endometrial cancers. Cancer Res., 57: 4736-4738, 1997.
29. Tashiro, H., Blazes, M., Wu, R., Cho, K., Bose, S., Wang, S., Li, J., Parsons, R., and Ellenson, L. Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res., 57: 3935-3940, 1997.
30. Guldberg, P., Straten, P., Birck, A., Ahrenkiel, V., Kirkin, A., and Zeuthen, J. Disruption of the MMAC1/PTEN gene by deletion or mutation is a frequent event in malignant melanoma. Cancer Res., 57: 3660-3663, 1997.
31. Kamb, A., Shattuck-Eidens, D., Eeles, R., Liu, Q., Gruis, N. A., Ding, W., Hussey, C., Tran, T., Miki, Y., and Weaver-Feldhaus, J. Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus. Nat. Genet., 8: 23-26, 1994.