Differential roles of segmented filamentous bacteria and clostridia in development of the intestinal immune system

Infection and Immunity

Volumn 67, Issue 7, 1999, Pages 3504-3511

  Umesaki, Yoshinori ^a   Setoyama, Hiromi ^a   Matsumoto, Satoshi ^a   Imaoka, Akemi ^a   Itoh, Kikuji ^b  

^a YAKULT CENTRAL INSTITUTE FOR MICROBIOLOGICAL RESEARCH   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; T LYMPHOCYTE RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CLOSTRIDIUM; HOST RESISTANCE; IMMUNOSTIMULATION; INTESTINE FLORA; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 0033006564     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.67.7.3504-3511.1999     Document Type: Article

References (51)

1. Badiner, G., T. G. Goodman, and L. Lefrancois. 1993. Selection of intestinal intraepithelial lymphocyte T cell receptors: evidence for a dynamic tissue specific process. Int. Immunol. 5:223-226.
2. Balk, S. P., E. C. Ebert, R. L. Blumenthal, F. V. Mcdermott, K. W. Wucherpfenning, S. B. Landau, and R. S. Blumberg. 1991. Oligoclonal expansion and CD1 recognition by human intestinal intraepithelial lymphocytes. Science 253:1411-1415.
3. Barnard, J. A., G. J. Warwick, and L. I. Gold. 1993. Localization of transforming growth factor β isoforms in the normal murine small intestine and colon. Gastroenterology 105:67-73.
4. Beagley, K. W., J. H. Eldridge, H. Kiyono, M. P. Everson, J. P. Koopman, Y. Hirano, T. Kishimoto, and J. R. McGhee. 1989. Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells. J. Exp. Med. 169:2133-2148.
5. Berg, R. D., and D. C. Savage. 1975. Immune responses of specific pathogen-free and gnotobiotic mice to antigens of indigenous and nonindigenous microorganisms. Infect. Immun. 11:320-329.
6. Bry, L., P. G. Falk, T. Midvedt, and G. I. Gordon. 1996. A model of host-microbial interactions in an open ecosystem. Science 273:1380-1383.
7. Buzoni-Gatel, D., A. C. Lepage, H. Dimier-Poisson, D. T. Bout, and L. H. Kasper. 1997. Adoptive transfer of gut intraepithelial lymphocytes protects against murine infection with Toxoplasma gondii. J. Immunol. 158:5883-5889.
8. Camerini, V., B. C. Sydora, R. Aaranda, C. Nguyen, C. MacLean, W. H. McBride, and M. Kronenberg. 1998. Generation of intestinal mucosal lymphocytes in scid mice reconstituted with mature, thymus-derived T cells. J. Immunol. 160:2608-2618.
9. + T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: increased T helper cell type 1 response and ability to transfer disease. J. Exp. Med. 187:855-864.
10. Contractor, N. V., H. Bassiri, T. Reya, A. Y. Park, D. C. Baumgart, M. A. Wasik, S. G. Emerson, and S. R. Carding. 1998. Lymphoid hyperplasia, autoimmunity, and compromised intestinal intraepithelial lymphocyte development on colitis-free gnotobiotic IL-2-deficient mice. J. Immunol. 160:385-394.
11. Cumming, J. H., J. L. Rombeau, and T. Sakata (ed.). 1995. Physiological and clinical aspects of short-chain fatty acids. Cambridge University Press, Cambridge, England.
12. Davis, C. P., and D. C. Savage. 1974. Habitat, succession, attachment, and morphology of segmented, filamentous microbes indigenous to the murine gastrointestinal tract. Infect. Immun. 10:948-956.
13. Dianda, L., M. Hanby, N. A. Wright, A. Sebesteny, A. C. Hayday, and J. C. Owen. 1997. T cell receptor-αβ-deficient mice fail to develop colitis in the absence of microbial environment. Am. J. Pathol. 150:91-97.
14. 2-microglobulin expression on gamma interferon secretion and target cell lysis by intraepithelial lymphocytes during intestinal Listeria monocytogenes infection. Infect. Immun. 64:569-575.
15. Fujihashi, K., J. R. McGhee, M. Yamamoto, J. Peschon, and H. Kiyono. 1997. An interleukin-7 internet for intestinal intraepithelial T cell development: knock out ligand or receptor reveal differences in the immunodeficient state. Eur. J. Immunol. 27:2133-2138.
16. Garcia-Lafuente, A., M. Antolin, F. Guarner, E. Crespo, A. Salas, P. Forcada, M. Laguarda, J. Gavalda, J. A. Beana, J. Vilaseca, and J. R. Malabelada. 1997. Incrimination of anaerobic bacteria in the induction of experimental colitis. Am. J. Physiol. 272:G10-G15.
17. Griebel, P. J., and W. R. Hein. 1996. Expanding the role of Peyer's patches in B-cell ontogeny. Immunol. Today 1730-1739.
18. Guy-Grand, D., N. Cref-Benussan, B. Malissen, M. Malassis-Series, C. Briottet, and P. Vassali. 1991. Two gut intraepithelial lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation. J. Exp. Med. 173:471-481.
19. Guy-Grand, D., B. Rocha, P. Mintz, M. Malassis-Series, F. Selz, B. Malissen, and P. Vassall. 1994. Different use of T cell receptor transducing molecules on two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation. J. Exp. Med. 180:673-679.
20. Hamad, M., M. Whestsell, J. Wang, and R. Klein. 1997. T cell progenitors in the murine small intestine. Dev. Comp. Immunol. 21:435-442.
21. Helgeland, L., J. T. Vaage, B. Rolstad, T. Midvedt, and P. Brandtzaeg. 1996. Microbial colonization influences composition and T-cell receptor Vβ repertoire of intraepithelial lymphocytes in rat intestine. Immunology 89:494-501.
22. Helgeland, L., P. Brandtzaeg, B. Rolstad, and J. T. Vaage. 1997. Sequential development of intraepithelial lymphocytes γδ and αβ T lymphocytes expressing CD8 αβ in neonatal rat intestine: requirement for the thymus. Immunology 92:447-456.
23. Henegan, J. B. 1984. Physiology of the alimentary tract, p. 169-191. In M. E. Coates and B. E. Gustaffson (ed.), The germ-free animal in biomedical research. Laboratory Animals Ltd., London, England.
24. Imaoka, A., S. Matsumoto, H. Setoyama, Y. Okada, and Y. Umesaki. 1996. Proliferative recruitment of intestinal intraepithelial lymphocytes after microbial colonization of germ-free mice. Eur. J. Immunol. 26:945-948.
25. Imaoka, A., Y. Okada, S. Matsumoto, H. Setoyama, and Y. Umesaki. 1997. 16S ribosomal DNA sequence of segmented filamentous bacteria with special reference to inter-species and within-species variation of host animals. Syst. Appl. Microbiol. 20:418-422.
26. Itoh, K., and T. Mitsuoka. 1985. Characterization of clostridia isolated from faces of limited flora mice and their effect on caecal size when associated germ-free mice. Lab. Anim. 19:111-118.
27. Klassen, H. L. B., J. P. Koopman, F. G. J. Poelma, and A. C. Beynen. 1992. Intestinal, segmented, filamentous bacteria. FEMS Microbiol. Rev. 88:165-180.
28. Komano, H., Y. Fujiura, M. Kawaguchi, S. Matsumoto, Y. Hashimoto, S. Obana, P. Momberts, S. Tonegawa, H. Yamamoto, S. Itohara, M. Nanno, and H. Ishikawa. 1995. Homeostatic regulation of intestinal epithelia by intraepithelial γδ T cells. Proc. Natl. Acad. Sci. USA 92:6147-6151.
29. Koopman, J. P., A. M. Stadhouders, H. M. Kennis, and H. De Boer. 1989. The attachment of filamentous segmented micro-organisms to the distal ileum wall of the mouse: a scanning and transmission electron microscopy study. Lab. Anim. 21:48-52.
30. Kuhn, I., J. Lohler, D. Rennick, K. Rajewsky, and W. Muller. 1993. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75:263-274.
31. Lefrancois, L., and T. Goodman. 1989. In vivo modulation of cytolytic activity and Thy-1 expression in TCR-γδ+ intraepithelial lymphocytes. Science 243:1716-1718.
32. Matsumototo, S., Y. Okabe, H. Setoyama, H. Funahashi, Imaoka, Y. Okada, and Y. Umesaki. 1998. Inflammatory bowel disease-like enteritis and cecitis in a senescence-accelerated mouse (SAM) P1/Yit strain. Gut 43:71-78.
33. Mayer, L. 1998. Current concepts in mucosal immunity. I. Antigen presentation in the intestine: new rules and regulations. Am. J. Physiol. 274:G7-G9.
34. + intraepithelial lymphocytes. Infect. Immun. 64:2556-2562.
35. McGee, D. W., K. W. Beagley, W. K. Aicher, and J. R. McGhee. 1992. Transforming growth factor-β enhances interleukin-6 secretion by intestinal epithelial cells. Immunology 77:7-12.
36. Momberts, P., E. Mizoguchi, M. J. Grusby, L. H. Glimchner, A. K. Bhan, and S. Tonegawa. 1993. Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice. Cell 75:275-282.
37. Moreau, N. C., R. Ducluzeau, D. Guy-Grand, and M. C. Muller. 1978. Increase in the population of duodenal immunoglobulin A plasmocytes in axenic mice associated with different living or dead bacterial strains of intestinal origin. Infect. Immun. 21:532-539.
38. Mowat, A. M., and J. L. Vinty. 1997. The anatomical basis of intestinal immunity. Immunol. Rev. 156:145-166.
39. Page, S. T., L. Y. Bogatzki, J. A. Hamerman, C. H. Sweenie, P. J. Hogarth, V. Malissen, R. M. Perlmutter, and A. M. Pullen. 1998. Intestinal intraepithelial lymphocytes include precursors committed to the T cell receptor αβ lineage. Proc. Natl. Acad. Sci. USA 95:9459-9464.
40. Poussler, P., H. S. Teh, and M. Julius. 1993. Thymus-independent positive and negative selection of T cells expressing a major histocompatibility complex class I restricted transgenic T cell receptor α/β in the intestinal epithelium. J. Exp. Med. 178:1947-1957.
41. Regnault, A., J.-P. Levraud, A. Lim, A. Six, C. Moreau, A. Cumano, and P. Kourilsky. 1996. The expansion and selection of T cell receptor αβ intestinal epithelial T cell clones. Eur. J. Immunol. 26:914-921.
42. Rothkotter, H. J., and R. Pabst. 1989. Lymphocyte subsets in jejunal and ileal Peyer's patches of normal and gnotobiotic minipigs. Immunology 67:103-108.
43. Sadlack, B., H. Merz, H. Schorle, A. Schimpl, A. C. Feller, and I. Horak. 1993. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 75:253-261.
44. Saito, H., Y. Kanamori, T. Takemori, H. Nariuchi, E. Kubota, H. Takahashi-Iwanaga, T. Iwanaga, and H. Ishikawa. 1998. Generation of intestinal T cells from progenitors residing in gut crypt patches. Science 280:275-278.
45. Shroff, K. H., K. Meslin, and J. J. Cebra. 1995. Commensal enteric bacteria engender a self-limiting humoral mucosal immune response while permanently colonizing the gut. Infect. Immun. 63:3904-3913.
46. Snel, J., H. J. Block, W. Ludwig, F. G. J. Poelma, J. P. Koopman, and A. D. L. Akkermans. 1994. Phylogenetic characterization of Clostridium related segmented bacteria in mice based on 16S ribosomal analysis. Syst. Appl. Microbiol. 17:172-179.
47. Sundberg, J. P., C. O. Elson, H. Bedigian, and E. H. Birkenmeir. 1994. Spontaneous heritable colitis in a new substrain of C3H/Hej mice. Gastroenterology 107:1726-1735.
48. Umesaki, Y., H. Setoyama, S. Matsumoto, and Y. Okada. 1993. Expansion of αβ T-cell receptor-bearing intestinal intraepithelial lymphocytes after microbial colonization in germ-free mice and its independence from thymus. Immunology 79:32-37.
49. Umesaki, Y., Y. Okada, S. Matsumoto, and H. Setoyama. 1995. Segmented filamentous bacteria are indigenous bacteria that activate intraepithelial lymphocytes and induce MHC class II molecules and fucosyl asialo GM1 glycolipids on the small intestinal epithelial cells in ex-germ-free mouse. Microbiol. Immunol. 39:555-562.
50. Umesaki, Y., Y. Okada, A. Imaoka, H. Setoyama, and S. Matsumoto. 1997. Interaction between epithelial cells and bacteria, normal and pathogenic. Science 276:964-965.
51. Watanabe, M., Y. Ueno, T. Yajima, Y. Iwao, M. Tsuchiya, H. Ishikawa, S. Aiso, T. Hibi, and H. Ishii. 1995. Interleukin 7 is produced by human intestinal epithelial cells and regulates the proliferation of intestinal mucosal lymphocytes. J. Clin. Investig. 95:2945-2953.