Microbial colonization influences composition and T-cell receptor Vβ repertoire of intraepithelial lymphocytes in rat intestine

Immunology

Volumn 89, Issue 4, 1996, Pages 494-501

  Helgeland, L ^a   Vaage, J T ^a   Rolstad, B ^a   Midtvedt, T ^b   Brandtzaeg, P ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; T LYMPHOCYTE RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL COLONIZATION; CONTROLLED STUDY; FLOW CYTOMETRY; INTESTINE EPITHELIUM; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; T LYMPHOCYTE;

EID: 0029908813     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1996.d01-783.x     Document Type: Article

References (40)

1. TAKAGAKI Y., DECLOUX A., BONNEVILLE M. & TONEGAWA S. (1989) Diversity of γδ T-cell receptors on murine intestinal intraepithelial lymphocytes. Nature 339, 712.
2. LEFRANCOIS L. (1991) Phenotypic complexity of intraepithelial lymphocytes of the small intestine. J Immunol 147, 1746.
3. + lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation. J Exp Med 173, 471.
4. BRANDTZAEG P., HALSTENSEN T.S., SCOTT H., SOLLID L.M. & VALNES K. (1989) Epithelial homing of γβ T cells? Nature 341, 113.
5. + (T cell receptor α/β or γ/δ) and CD3 lymphocytes isolated from normal human gut epithelium display phenotypical features different from their counterparts in peripheral blood. Eur J Immunol 20, 1097.
6. + intraepithelial lymphocytes by apoptosis. Eur J Immunol 20, 2809.
7. BANDEIRA A., MOTA-SANTOS T., ITOHARA S. et al. (1990) Localization of γ/δ T cells to the intestinal epithelium is independent of normal microbial colonization. J Exp Med 172, 239.
8. KAWAGUCHI M., NANNO M., UMESAKI Y. et al. (1993) Cytolytic activity of intestinal intraepithelial lymphocytes in germ-free mice is strain dependent and determined by T cells expressing γδ T-cell antigen receptors. Proc Natl Acad Sci USA 90, 8591.
9. UMESAKI Y., SETOYAMA H., MATSUMOTO S. & OKADA Y. (1993) Expansion of αβ T-cell receptor-bearing intestinal intraepithelial lymphocytes after microbial colonization in germ-free mice and its independence from thymus. Immunology 79, 32.
10. + T cells in vivo. J Immunol 154, 5684.
11. BADINER G., GOODMAN T.G. & LEFRANCOIS L. (1993) Selection of intestinal intraepithelial lymphocyte T cell receptors: evidence for a dynamic tissue-specific process. Int Immunol 5, 223.
12. BALK S.P., EBERT E.C., BLUMENTHAL R.L. et al. (1991) Oligoclonal expansion and CD1 recognition by human intestinal intraepithelial lympohocytes. Science 253, 1411.
13. BLUMBERG R.S., YOCKEY C.E., GROSS G.G., EBERT E.C. & BALK S.P. (1993) Human intestinal intraepithelial lymphocytes are derived from a limited number of T cell clones that utilize multiple Vβ T cell receptor genes J Immunol 150, 5144.
14. VAN KERCKHOVE C., RUSSEL G.J., DEUSCH K. et al. (1992) Oligoclonality of human intestinal intraepithelial T cells. J Exp Med 175, 57.
15. REGNAULT A., CUMANO A., VASSALLI P., GUY-GRAND D. & KOURILSKY P. (1994) Oligoclonal repertoire of the CD8αα and the CD8αβ TCR-α/β murine intestinal intraepithelial T lymphocytes: evidence for the random emergence of T cells. J Exp Med 180, 1345.
16. POUSSIER P. & JULIUS M. (1994) Thymus independent T cell development and selection in the intestinal epithelium. Annu Rev Immunol 12, 521.
17. ROCHA B., GUY-GRAND D. & VASSALLI P. (1995) Extrathymic T cell differentiation. Curr Opin Immunol 7, 235.
18. CUFF C.F., CEBRA C.K., RUBIN D.H. & CEBRA J.J. (1993) Developmental relationship between cytotoxic α/β T cell receptor-positive intraepithelial lymphocytes and Peyer's patch lymphocytes. Eur J Immunol 23, 1333.
19. + gut intraepithelial lymphocytes, lytic for parasite-infected enterocytes. J Immunol 153, 4596.
20. + and are thymus-dependent. Eur J Immunol 20, 1193.
21. NICOLLS M.R., AVERSA G.G., PEARCE N.W. et al. (1993) Induction of long-term specific tolerance to allografts in rats by therapy with an anti-CD3-like monoclonal antibody. Transplantation 55, 459.
22. HÜNIG T., WALLNY H.-J., HARTLEY J.K., LAWETZKY A. & TIEFENTHALER G. (1989) A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. J Exp Med 169, 73.
23. KÜHNLEIN P., PARK J.-H., HERMANN T., ELBE A. & HÜNIG T. (1994) Identification and characterization of rat γ/δ T lymphocytes in peripheral lymphoid organs, small intestine, and skin with a monoclonal antibody to a constant determinant of the γ/δ T cell receptor. J Immunol 153, 979.
24. TORRES-NAGEL N., KRAUS E., BROWN M.H. et al. (1992) Differential thymus dependence of rat CD8 isoform expression. Eur J Immunol 21, 2841.
25. CERF-BENSUSSAN N., GUY-GRAND D., LISOWSKA-GROSPIERRE B., GRISCELLI C. & BHAN A.K. (1986) A monoclonal antibody specific for rat intestinal lymphocytes. J Immunol 136, 76.
26. TORRES-NAGEL N.E., GOLD D.P. & HÜNIG T. (1993) Identification of rat Tcrb-V8.2, 8.5, and 10 gene products by monoclonal antibodies. Immunogenetics 37, 305.
27. KAMPINGA J., KROESE F.G.M., POL G.H. et al. (1989) A monoclonal antibody to a determinant of the rat T cell receptor expressed receptor expressed by a minor subset of T cells. Int Immunol 1, 289.
28. TORRES-NAGEL N.E., GIEGERICH G., GOLD D.P. & HÜNIG T. (1994) Identification of rat Tcra-V 4 and 8 gene products by monoclonal antibodies and cDNA sequence. Immunogenetics 39, 367.
29. + intestinal intraepithelial lymphocytes in rats. Eur J Immunol 22, 159.
30. GROSS G.G., SCHWARTZ V.L., STEVENS C., EBERT, E.G., BLUMBERG R.S. & BALK S.P. (1994) Distribution of dominant T cell receptor β chains in human intestinal mucosa. J Exp Med 180, 1337.
31. β1 repertoire selection. EMBO J 13, 808.
32. KONINGSBERGER J., CHOTT A., LOGTENBERG T., BLUMBERG R. & BALK S. (1995) The TCR αß repertoire in human fetal mucosa during gestation. Clin Immunol Immunopathol 76, Part 2 of 2 parts; Abstract No. 318.
33. BURKE S., LANDAU S., GREEN R. et al. (1994) Rat cluster of differentiation 1 molecule: expression on the surface of intestinal epithelial cells and hepatocytes. Gastroenterology 106, 1143.
34. HERSHBERG R., EGHTESADY P., SYDORA B. et al. (1990) Expression of the thymus leukemia antigen in mouse intestinal epithelium Proc Natl Acad Sci USA 87, 9727.
35. PAMER E.G., WANG C.-R., FLAHERTY L., LINDAHL K.F. & BEVAN M.J. (1992) H-2M3 presents a Listeria monocytogenes peptide to cytotoxic T lymphoctyes. Cell 70, 215.
36. SIELING P.A., CHATTERJEE D., PORCELLI S.A. et al. (1995) CD1-restricted T cell recognition of microbial lipoglycan antigens. Science 269, 227.
37. ALDRICH C.J., WALTRIP R., HERMEL E. et al. (1992) T cell recognition of Qa-1b antigens on cells lacking a functional Tap-2 transporter. J Immunol 149, 3773.
38. OFFIT P.A. & DUDZIK K.I. (1989) Rotavirus-specific cytotoxic T lymphocytes appear at the intestinal mucosal surface after rotavirus infection. J Virol 63, 3507.
39. + intraepithelial lymphocytes in the murine small intestine. Immunology 86, 212.
40. DOGAN A., DUNN-WALTERS D.K., MACDONALD T.T. & SPENCER J. (1996) Demonstration of local clonality of mucosal T cells in human colon using DNA obtained by microdissection of immunohistochemically-stained tissue sections. Eur J Immunol 26, 1240.