-
1
-
-
0010105962
-
Inhition of phosphoribosylaminoimidazolcarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates
-
1 Allegra CJ, Drake JC, Jolivet J, et al: Inhition of phosphoribosylaminoimidazolcarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates. Proc Natl Acad Sci U S A 1985, 82:4881-4885.
-
(1985)
Proc Natl Acad Sci U S A
, vol.82
, pp. 4881-4885
-
-
Allegra, C.J.1
Drake, J.C.2
Jolivet, J.3
-
2
-
-
0022637441
-
Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase and 5'-adeny-late deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide
-
2 Bagott JE, Vaughan WH, Hudson BB: Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase and 5'-adeny-late deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide. Biochem J 1986, 236:193-200.
-
(1986)
Biochem J
, vol.236
, pp. 193-200
-
-
Bagott, J.E.1
Vaughan, W.H.2
Hudson, B.B.3
-
3
-
-
0024454449
-
Increased adenosine concentration in blood from ischemic myocardium by AICA-riboside: Effects on flow, granulocytes and injury
-
3 Gruber HE, Hoffer ME, McAllister DR, et al: Increased adenosine concentration in blood from ischemic myocardium by AICA-riboside: effects on flow, granulocytes and injury. Circulation 1989, 80:1400-1411.
-
(1989)
Circulation
, vol.80
, pp. 1400-1411
-
-
Gruber, H.E.1
Hoffer, M.E.2
McAllister, D.R.3
-
4
-
-
0025126844
-
Selective adenosine release from human B but not T lymphoid cell line
-
4 Barankiewicz J, Ranlov G, Jimenez R, et al: Selective adenosine release from human B but not T lymphoid cell line. J Biol Chem 1990, 265:15738-15743.
-
(1990)
J Biol Chem
, vol.265
, pp. 15738-15743
-
-
Barankiewicz, J.1
Ranlov, G.2
Jimenez, R.3
-
5
-
-
4244213854
-
Inhibition of adenosine deaminase and 5-adenosyl homocysteine hydrolase by 5-aminoimidazole-4-carboxamide riboside
-
5 Ha T, Morgan SL, Vaughan WH, et al: Inhibition of adenosine deaminase and 5-adenosyl homocysteine hydrolase by 5-aminoimidazole-4-carboxamide riboside. FASEB J 1992, 6:1210-1215.
-
(1992)
FASEB J
, vol.6
, pp. 1210-1215
-
-
Ha, T.1
Morgan, S.L.2
Vaughan, W.H.3
-
6
-
-
0032518281
-
Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5'-nucleotidase-mediated conversion of adenine nucleotides
-
6 Morabito L, Montesinos MC, Schreibman DM, et al: Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5'-nucleotidase-mediated conversion of adenine nucleotides. J Clin Invest 1998, 101:295-300.
-
(1998)
J Clin Invest
, vol.101
, pp. 295-300
-
-
Morabito, L.1
Montesinos, M.C.2
Schreibman, D.M.3
-
7
-
-
0025967399
-
Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells
-
7 Cronstein BN, Kramer SB, Weissmann G, et al: Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells. Proc Natl Acad Sci U S A 1991, 88:2441-2445.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 2441-2445
-
-
Cronstein, B.N.1
Kramer, S.B.2
Weissmann, G.3
-
8
-
-
0027139914
-
The antiinflammatory mechanism of methotrexate: Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vitro model of inflammation
-
8 Cronstein BN, Naime D, Ostad E: The antiinflammatory mechanism of methotrexate: increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vitro model of inflammation. J Clin Invest 1993, 92:2675-2682.
-
(1993)
J Clin Invest
, vol.92
, pp. 2675-2682
-
-
Cronstein, B.N.1
Naime, D.2
Ostad, E.3
-
9
-
-
0020554177
-
Adenosine: A physiological modulator of superoxide anion generation by human neutrophils
-
9 Cronstein BN, Kramer SB, Weissmann G, et al: Adenosine: a physiological modulator of superoxide anion generation by human neutrophils. J Exp Med 1983, 158:1160-1177.
-
(1983)
J Exp Med
, vol.158
, pp. 1160-1177
-
-
Cronstein, B.N.1
Kramer, S.B.2
Weissmann, G.3
-
10
-
-
0022397930
-
Adenosine, a physiologic modulator of superoxide anion generation by human neutrophils: Adenosine acts via an A2 receptor on human neutrophils
-
10 Cronstein BN, Rosenstein ED, Kramer SB, et al: Adenosine, a physiologic modulator of superoxide anion generation by human neutrophils: adenosine acts via an A2 receptor on human neutrophils. J Immunol 1985, 135:1366-1371.
-
(1985)
J Immunol
, vol.135
, pp. 1366-1371
-
-
Cronstein, B.N.1
Rosenstein, E.D.2
Kramer, S.B.3
-
11
-
-
0026507232
-
Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors
-
11 Cronstein BN, Levin RE, Philips MR, et al: Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors. J Immunol 1992, 148:2201-2206.
-
(1992)
J Immunol
, vol.148
, pp. 2201-2206
-
-
Cronstein, B.N.1
Levin, R.E.2
Philips, M.R.3
-
12
-
-
0029658925
-
Adenosine A2 receptor-induced inhibition of leukotriene B4 synthesis in whole blood ex vivo
-
12 Krump E, Lemay G, Borgeat D: Adenosine A2 receptor-induced inhibition of leukotriene B4 synthesis in whole blood ex vivo. Br J Pharmacol 1996, 117:1639-1644.
-
(1996)
Br J Pharmacol
, vol.117
, pp. 1639-1644
-
-
Krump, E.1
Lemay, G.2
Borgeat, D.3
-
13
-
-
0029360536
-
Acting via A2 receptors, adenosine inhibits production of tumor necrosis factor α of endotoxin-stimulated polymorphonuclear leukocytes
-
13 Thiel M, Chouker A: Acting via A2 receptors, adenosine inhibits production of tumor necrosis factor α of endotoxin-stimulated polymorphonuclear leukocytes. J Lab Clin Med 1995, 126:275-282.
-
(1995)
J Lab Clin Med
, vol.126
, pp. 275-282
-
-
Thiel, M.1
Chouker, A.2
-
14
-
-
0029915543
-
Inhibition of TNFα expression by adenosine: Role of A3 adenosine receptors
-
14 Sajjadi FG, Takabayashi K, Foster AC, et al: Inhibition of TNFα expression by adenosine: Role of A3 adenosine receptors. J Immunol 1996, 156:3435-3442.
-
(1996)
J Immunol
, vol.156
, pp. 3435-3442
-
-
Sajjadi, F.G.1
Takabayashi, K.2
Foster, A.C.3
-
15
-
-
0028061703
-
Differential regulatory effects of adenosine on cytokine release by activated human monocytes
-
15 Bouma MG, Stad RK, van den Wildenberg FA, et al: Differential regulatory effects of adenosine on cytokine release by activated human monocytes. J Immunol 1994, 1:4159-4168.
-
(1994)
J Immunol
, vol.1
, pp. 4159-4168
-
-
Bouma, M.G.1
Stad, R.K.2
Van Den Wildenberg, F.A.3
-
16
-
-
0030664737
-
The mechanism of action of methotrexate
-
16 Cronstein BN: The mechanism of action of methotrexate. Rheum Dis Clin North Am 1997, 23:739-755.
-
(1997)
Rheum Dis Clin North Am
, vol.23
, pp. 739-755
-
-
Cronstein, B.N.1
-
17
-
-
0029933663
-
Adenosine enhances IL-10 secretion by human monocytes
-
17 Le Moine O, Stordeur P, Schandene L, et al: Adenosine enhances IL-10 secretion by human monocytes. J Immunol 1996, 156:4408-4414.
-
(1996)
J Immunol
, vol.156
, pp. 4408-4414
-
-
Le Moine, O.1
Stordeur, P.2
Schandene, L.3
-
18
-
-
0031961765
-
Antiinflammatory and immunoregulatory action of methotrexate in the treatment of rheumatoid arthritis: Evidence of increased IL-4 and IL-10 gene expression demonstrated in vitro by competitive reverse transcriptase-polymerase chain reaction
-
18 Constantin A, Loubet-Lescoulié P, Lambert N, et al: Antiinflammatory and immunoregulatory action of methotrexate in the treatment of rheumatoid arthritis: evidence of increased IL-4 and IL-10 gene expression demonstrated in vitro by competitive reverse transcriptase-polymerase chain reaction. Arthritis Rheum 1998, 41:48-57.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 48-57
-
-
Constantin, A.1
Loubet-Lescoulié, P.2
Lambert, N.3
-
19
-
-
0029968687
-
Adenosine inhibitis cytokine release and expression of adhesion molecules by activated human endothelial cells
-
19 Bouma MG, van den Wildenberg FA, Buurman WA: Adenosine inhibitis cytokine release and expression of adhesion molecules by activated human endothelial cells. Am J Physiol 1996, 39:522-529.
-
(1996)
Am J Physiol
, vol.39
, pp. 522-529
-
-
Bouma, M.G.1
Van Den Wildenberg, F.A.2
Buurman, W.A.3
-
20
-
-
0018835239
-
The effect of methotrexate and hydroxyurea on neutrophil chemotaxis
-
20 Cream JJ, Pole DS: The effect of methotrexate and hydroxyurea on neutrophil chemotaxis. Br J Dermatol 1980, 102:557-563.
-
(1980)
Br J Dermatol
, vol.102
, pp. 557-563
-
-
Cream, J.J.1
Pole, D.S.2
-
21
-
-
0031874951
-
Methotrexate reduces inflammatory cell numbers, expression of monokines and of adhesion molecules in synovial tissue of patients with rheumatoid arthritis
-
Dolhain RJ, Tak PP, Dijkmann BA, et al: Methotrexate reduces inflammatory cell numbers, expression of monokines and of adhesion molecules in synovial tissue of patients with rheumatoid arthritis. Br J Rheumatol 1998, 37:502-508.
-
(1998)
Br J Rheumatol
, vol.37
, pp. 502-508
-
-
Dolhain, R.J.1
Tak, P.P.2
Dijkmann, B.A.3
-
22
-
-
0028123760
-
Mechanisms of methotrexate action in rheumatoid arthritis: Selective decrease in synovial collagenase gene expression
-
22 Firestein GS, Paine MM, Boyle DL, et al: Mechanisms of methotrexate action in rheumatoid arthritis: selective decrease in synovial collagenase gene expression. Arthritis Rheum 1994, 37:193-200.
-
(1994)
Arthritis Rheum
, vol.37
, pp. 193-200
-
-
Firestein, G.S.1
Paine, M.M.2
Boyle, D.L.3
-
23
-
-
0029896521
-
Inhibition of synoviocyte collagenase gene expression by adenosine receptor stimulation
-
23 Boyle DL, Sajjadi FG, Firestein GS: Inhibition of synoviocyte collagenase gene expression by adenosine receptor stimulation. Arthritis Rheum 1996, 39:923-930.
-
(1996)
Arthritis Rheum
, vol.39
, pp. 923-930
-
-
Boyle, D.L.1
Sajjadi, F.G.2
Firestein, G.S.3
-
24
-
-
0027181961
-
Adenosine and a related carbocyclic nucleoside analogue selectively inhibit tumor necrosis factor-alpha production and protect mice against endotoxin challenge
-
24 Parmely MJ, Zhou WW, Edwards CK, et al: Adenosine and a related carbocyclic nucleoside analogue selectively inhibit tumor necrosis factor-alpha production and protect mice against endotoxin challenge. J Immunol 1993, 151:389-396.
-
(1993)
J Immunol
, vol.151
, pp. 389-396
-
-
Parmely, M.J.1
Zhou, W.W.2
Edwards, C.K.3
-
25
-
-
0030612493
-
Adenosine a1 receptor promotion of multinucleated giant cell formation by human monocytes: A mechanism for methotrexate-induced nodulosis in rheumatoid arthritis
-
25 Merrill JT, Shen C, Schreibman D, et al: Adenosine A1 receptor promotion of multinucleated giant cell formation by human monocytes: a mechanism for methotrexate-induced nodulosis in rheumatoid arthritis. Arthritis Rheum 1997, 40:1308-1315.
-
(1997)
Arthritis Rheum
, vol.40
, pp. 1308-1315
-
-
Merrill, J.T.1
Shen, C.2
Schreibman, D.3
-
26
-
-
0031452023
-
Adenosine plasma levels after low dose methotrexate administration
-
26 Pasini FL, Capecchi PL, Di Perri T: Adenosine plasma levels after low dose methotrexate administration [letter to the editor]. J Rheumatol 1997, 24:2492-2493.
-
(1997)
J Rheumatol
, vol.24
, pp. 2492-2493
-
-
Pasini, F.L.1
Capecchi, P.L.2
Di Perri, T.3
-
27
-
-
0028919570
-
Aminophylline for methotrexate-induced neurotoxicity
-
27 Bernini JC, Fort DW, Griener JC, et al: Aminophylline for methotrexate-induced neurotoxicity. Lancet 1995, 345:544-547.
-
(1995)
Lancet
, vol.345
, pp. 544-547
-
-
Bernini, J.C.1
Fort, D.W.2
Griener, J.C.3
-
28
-
-
0027171787
-
Renal effects of low dose methotrexate in rheumatoid arthritis
-
28 Seidmann P, Muller-Suur R, Ekman E: Renal effects of low dose methotrexate in rheumatoid arthritis. J Rheumatol 1993, 20:1126-1128.
-
(1993)
J Rheumatol
, vol.20
, pp. 1126-1128
-
-
Seidmann, P.1
Muller-Suur, R.2
Ekman, E.3
-
29
-
-
0028923126
-
Therapeutic use of theophylline to antagonize renal effects of adenosine
-
29 Osswald H, Gleiter C, Muhlbauer B: Therapeutic use of theophylline to antagonize renal effects of adenosine. Clin Nephrol 1995, 1(suppl 43):33-37.
-
(1995)
Clin Nephrol
, vol.1
, Issue.SUPPL. 43
, pp. 33-37
-
-
Osswald, H.1
Gleiter, C.2
Muhlbauer, B.3
-
30
-
-
0029118909
-
The antiinflammatory effects of an adenosine kinase inhibitor are mediated by adenosine
-
30 Cronstein BN, Naime D, Firestein GS: The antiinflammatory effects of an adenosine kinase inhibitor are mediated by adenosine. Arthritis Rheum 1995, 38:1040-1045.
-
(1995)
Arthritis Rheum
, vol.38
, pp. 1040-1045
-
-
Cronstein, B.N.1
Naime, D.2
Firestein, G.S.3
-
31
-
-
0028288008
-
Protective effect of an adenosine kinase inhibitor in septic shock
-
31 Firestein GS, Boyle D, Bullowsky DA, et al: Protective effect of an adenosine kinase inhibitor in septic shock. J Immunol 1994, 152:5853-5859.
-
(1994)
J Immunol
, vol.152
, pp. 5853-5859
-
-
Firestein, G.S.1
Boyle, D.2
Bullowsky, D.A.3
-
32
-
-
0029069956
-
Anti-inflammatory effects of an adenosine kinase inhibitor: Decreased neutrophil accumulation and vascular leakage
-
32 Rosengren S, Bang BW, Firestein GS: Anti-inflammatory effects of an adenosine kinase inhibitor: decreased neutrophil accumulation and vascular leakage. J Immunol 1995, 154:5444-5451.
-
(1995)
J Immunol
, vol.154
, pp. 5444-5451
-
-
Rosengren, S.1
Bang, B.W.2
Firestein, G.S.3
-
33
-
-
0030026499
-
The antiinflammatory mechanism of sulfasalazine is related to adenosine release at inflamed sites
-
33 Gadangi P, Longaker M, Naime D, et al: The antiinflammatory mechanism of sulfasalazine is related to adenosine release at inflamed sites. J Immunol 1996, 156:1937-1941.
-
(1996)
J Immunol
, vol.156
, pp. 1937-1941
-
-
Gadangi, P.1
Longaker, M.2
Naime, D.3
-
34
-
-
0022410582
-
Polyglutamation of methotrexate: Is methotrexate a prodrug?
-
34 Chabner BA, Allegra A, Curt C, et al: Polyglutamation of methotrexate: is methotrexate a prodrug? J Clin Invest 1985, 76:907-912.
-
(1985)
J Clin Invest
, vol.76
, pp. 907-912
-
-
Chabner, B.A.1
Allegra, A.2
Curt, C.3
-
35
-
-
0020573614
-
Inhibition of methionine transport by methotrexate in mitogen stimulated human lymphocytes
-
35 Scanlan KJ, Berkowitz K, Pallai ME, et al: Inhibition of methionine transport by methotrexate in mitogen stimulated human lymphocytes. Cancer Treat Rep 1983, 67:631-639.
-
(1983)
Cancer Treat Rep
, vol.67
, pp. 631-639
-
-
Scanlan, K.J.1
Berkowitz, K.2
Pallai, M.E.3
-
36
-
-
0025362827
-
Methionine metabolism in mammals
-
36 Finkelstein JD: Methionine metabolism in mammals. J Nutr Biochem 1990, 1:228-237.
-
(1990)
J Nutr Biochem
, vol.1
, pp. 228-237
-
-
Finkelstein, J.D.1
-
38
-
-
0027142564
-
Levels of urinary polyamines in patients with rheumatoid arthritis
-
38 Furumitsu Y, Yukioka K, Kojima A, et al: Levels of urinary polyamines in patients with rheumatoid arthritis. J Rheumatol 1993, 20:1661-1665.
-
(1993)
J Rheumatol
, vol.20
, pp. 1661-1665
-
-
Furumitsu, Y.1
Yukioka, K.2
Kojima, A.3
-
39
-
-
0026721611
-
Polyamine levels in synovial tissues and synovial fluids of patients with rheumatoid arthritis
-
39 Yukioka K, Wakitani S, Yukioka M, et al: Polyamine levels in synovial tissues and synovial fluids of patients with rheumatoid arthritis. J Rheumatol 1992, 19:689-692.
-
(1992)
J Rheumatol
, vol.19
, pp. 689-692
-
-
Yukioka, K.1
Wakitani, S.2
Yukioka, M.3
-
40
-
-
0025352428
-
The in vitro effects of methotrexate on peripheral blood mononuclear cells: Modulation by methyl donor and spermidine
-
40 Nesker G, Moore TL: The in vitro effects of methotrexate on peripheral blood mononuclear cells: modulation by methyl donor and spermidine. Arthritis Rheum 1990, 33:954-959.
-
(1990)
Arthritis Rheum
, vol.33
, pp. 954-959
-
-
Nesker, G.1
Moore, T.L.2
-
41
-
-
0024567063
-
Increased polyamines may down-regulate interleukin 2 production in rheumatoid arthritis
-
41 Flescher E, Bowlin TL, Ballester A, et al: Increased polyamines may down-regulate interleukin 2 production in rheumatoid arthritis. J Clin Invest 1989, 83:1356-1362.
-
(1989)
J Clin Invest
, vol.83
, pp. 1356-1362
-
-
Flescher, E.1
Bowlin, T.L.2
Ballester, A.3
-
42
-
-
0026535773
-
Regulation of IL-2 production by mononuclear cells from rheumatoid arthritis synovial fluids
-
42 Flescher E, Bowlin TL, Talal N: Regulation of IL-2 production by mononuclear cells from rheumatoid arthritis synovial fluids. Clin Exp Immunol 1992, 87:435-437.
-
(1992)
Clin Exp Immunol
, vol.87
, pp. 435-437
-
-
Flescher, E.1
Bowlin, T.L.2
Talal, N.3
-
43
-
-
0027957782
-
The mechanisms of action of methotrexate in rheumatoid arthritis: The search continues
-
43 Kremer MJ: The mechanisms of action of methotrexate in rheumatoid arthritis: the search continues. J Rheumatol 1994, 21:1-5.
-
(1994)
J Rheumatol
, vol.21
, pp. 1-5
-
-
Kremer, M.J.1
-
44
-
-
0025075147
-
Suppression of rheumatoid factor production by methotrexate in patients with rheumoid arthritis
-
44 Alarcon GS, Schrohenloher RE, Bartolucci AA, et al: Suppression of rheumatoid factor production by methotrexate in patients with rheumoid arthritis. Arthritis Rheum 1990, 33:1156-1161.
-
(1990)
Arthritis Rheum
, vol.33
, pp. 1156-1161
-
-
Alarcon, G.S.1
Schrohenloher, R.E.2
Bartolucci, A.A.3
-
45
-
-
0022137053
-
Weekly pulse methotrexate in rheumatoid arthritis: Clinical and immunological effects in a randomized double-blind study
-
45 Anderson PA, West SG, O'Dell JR, et al: Weekly pulse methotrexate in rheumatoid arthritis: clinical and immunological effects in a randomized double-blind study. Ann Intern Med 1985, 103:489-496.
-
(1985)
Ann Intern Med
, vol.103
, pp. 489-496
-
-
Anderson, P.A.1
West, S.G.2
O'Dell, J.R.3
-
46
-
-
0025370028
-
Response of immunoregulatory lymphocyte subsets to methotrexate in rheumatoid arthritis
-
46 Calabrese LH, Taylor JV, Wilke WS, et al: Response of immunoregulatory lymphocyte subsets to methotrexate in rheumatoid arthritis. Cleve Clin J Med 1990, 57:232-241.
-
(1990)
Cleve Clin J Med
, vol.57
, pp. 232-241
-
-
Calabrese, L.H.1
Taylor, J.V.2
Wilke, W.S.3
-
47
-
-
0024542302
-
Antiproliferate effects of methotrexate on peripheral blood mononuclear cells
-
47 Olsen NJ, Murray LM: Antiproliferate effects of methotrexate on peripheral blood mononuclear cells. Arthritis Rheum 1989, 32:378-388.
-
(1989)
Arthritis Rheum
, vol.32
, pp. 378-388
-
-
Olsen, N.J.1
Murray, L.M.2
-
48
-
-
0027978987
-
Cell-type specific response of peripheral blood lymphocytes to methotrexate in the treatment of rheumatoid arthritis
-
48 Wascher TC, Hermann J, Brezinschek HP, et al: Cell-type specific response of peripheral blood lymphocytes to methotrexate in the treatment of rheumatoid arthritis. Clin Invest 1994, 72:535-540.
-
(1994)
Clin Invest
, vol.72
, pp. 535-540
-
-
Wascher, T.C.1
Hermann, J.2
Brezinschek, H.P.3
-
49
-
-
0025553522
-
Methotrexate: Mechanism of action in rheumatoid arthritis
-
49 Segal R, Yaron M, Tartakovsky B, et al: Methotrexate: mechanism of action in rheumatoid arthritis. Semin Arthritis Rheum 1990, 20:190-199.
-
(1990)
Semin Arthritis Rheum
, vol.20
, pp. 190-199
-
-
Segal, R.1
Yaron, M.2
Tartakovsky, B.3
-
50
-
-
0032528186
-
Immunosuppressive properties of methotrexate: Apoptosis and clonal deletion of activated peripheral T cells
-
50 Genestier L, Paillot R, Fournel S, et al: Immunosuppressive properties of methotrexate: apoptosis and clonal deletion of activated peripheral T cells. J Clin Invest 1998; 102:322-328.
-
(1998)
J Clin Invest
, vol.102
, pp. 322-328
-
-
Genestier, L.1
Paillot, R.2
Fournel, S.3
-
51
-
-
0023613590
-
Severe flare of rheumatoid arthritis after discontinuation of long-term methotrexate therapy: Double-blind study
-
51 Kremer JM, Rynes RI, Bartholomew BL: Severe flare of rheumatoid arthritis after discontinuation of long-term methotrexate therapy: double-blind study. Am J Med 1987, 82:781-786.
-
(1987)
Am J Med
, vol.82
, pp. 781-786
-
-
Kremer, J.M.1
Rynes, R.I.2
Bartholomew, B.L.3
-
52
-
-
0026695292
-
Acute and chronic suppression of leukotriene B4 synthesis ex vivo in neutrophils from patients with rheumatoid arthritis beginning treatment with methotrexate
-
52 Sperling RI, Benincaso AI, Anderson RJ, et al: Acute and chronic suppression of leukotriene B4 synthesis ex vivo in neutrophils from patients with rheumatoid arthritis beginning treatment with methotrexate. Arthritis Rheum 1992, 35:370-384.
-
(1992)
Arthritis Rheum
, vol.35
, pp. 370-384
-
-
Sperling, R.I.1
Benincaso, A.I.2
Anderson, R.J.3
-
53
-
-
0028010087
-
The effect of methotrexate on ex vivo lipoxygenase metabolism in neutrophils from patients with rheumatoid arthritis
-
53 Hawkes JS, Cleland LG, Proudman SM, et al: The effect of methotrexate on ex vivo lipoxygenase metabolism in neutrophils from patients with rheumatoid arthritis. J Rheumatol 1994, 21:55-58.
-
(1994)
J Rheumatol
, vol.21
, pp. 55-58
-
-
Hawkes, J.S.1
Cleland, L.G.2
Proudman, S.M.3
-
54
-
-
0025193240
-
Inhibition of leukotriene b4 synthesis in neutrophils from patients with rheumatoid arthritis by a single oral dose of methotrexate
-
54 Sperling RI, Coblyn JG, Larkin JK, et al: Inhibition of leukotriene B4 synthesis in neutrophils from patients with rheumatoid arthritis by a single oral dose of methotrexate. Arthritis Rheum 1990, 33:1149-1155.
-
(1990)
Arthritis Rheum
, vol.33
, pp. 1149-1155
-
-
Sperling, R.I.1
Coblyn, J.G.2
Larkin, J.K.3
-
55
-
-
0026740418
-
Effects of a single dose of methotrexate on 5-and 12-lipoxygenase products in patients with rheumatoid arthritis
-
55 Leroux JL, Damon M, Chavis C, et al: Effects of a single dose of methotrexate on 5-and 12-lipoxygenase products in patients with rheumatoid arthritis. J Rheumatol 1992, 19:863-866.
-
(1992)
J Rheumatol
, vol.19
, pp. 863-866
-
-
Leroux, J.L.1
Damon, M.2
Chavis, C.3
-
56
-
-
0023236208
-
Fish-oil fatty acid supplementation in active rheumatoid arthritis: A double-blinded, controlled, cross-over study
-
56 Kremer JM, Jubiz W, Michalek A, et al: Fish-oil fatty acid supplementation in active rheumatoid arthritis: a double-blinded, controlled, cross-over study. Ann Intern Med 1987, 166:497-503.
-
(1987)
Ann Intern Med
, vol.166
, pp. 497-503
-
-
Kremer, J.M.1
Jubiz, W.2
Michalek, A.3
-
57
-
-
0025374441
-
Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis: Clinical and immunological effects
-
57 Kremer JM, Lawrence DA, Jubiz W, et al: Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis: clinical and immunological effects. Arthritis Rheum 1990, 33:810-820.
-
(1990)
Arthritis Rheum
, vol.33
, pp. 810-820
-
-
Kremer, J.M.1
Lawrence, D.A.2
Jubiz, W.3
-
58
-
-
0031887481
-
Methotrexate and cyclooxygenase metabolism in cultured human rheumatoid synoviocytes
-
58 Vergne P, Liagre B, Bertin P, et al: Methotrexate and cyclooxygenase metabolism in cultured human rheumatoid synoviocytes. J Rheumatol 1998, 25:433-440.
-
(1998)
J Rheumatol
, vol.25
, pp. 433-440
-
-
Vergne, P.1
Liagre, B.2
Bertin, P.3
-
59
-
-
0023951655
-
Methotrexate inhibits macrophage activation as well as vascular and cellular inflammatory events in rat adjuvant induced arteritis
-
59 Johnson WJ, DiMartino MJ, Meunier PC, et al: Methotrexate inhibits macrophage activation as well as vascular and cellular inflammatory events in rat adjuvant induced arteritis. J Rheumatol 1988, 15:745-749.
-
(1988)
J Rheumatol
, vol.15
, pp. 745-749
-
-
Johnson, W.J.1
Dimartino, M.J.2
Meunier, P.C.3
-
60
-
-
0023836669
-
Studies on the effect of methotrexate on macrophage function
-
60 Hu S-K, Mitcho YL, Oronsky AL, et al: Studies on the effect of methotrexate on macrophage function. J Rheumatol 1988, 15:206-209.
-
(1988)
J Rheumatol
, vol.15
, pp. 206-209
-
-
Hu, S.-K.1
Mitcho, Y.L.2
Oronsky, A.L.3
-
61
-
-
0026615104
-
The effects of methotrexate on inferleukin 1 in patients with rheumatoid arthritis
-
61 Chang D-M, Weinblatt ME, Schur PH: The effects of methotrexate on inferleukin 1 in patients with rheumatoid arthritis. J Rheumatol 1992, 19:1678-1682.
-
(1992)
J Rheumatol
, vol.19
, pp. 1678-1682
-
-
Chang, D.-M.1
Weinblatt, M.E.2
Schur, P.H.3
-
62
-
-
0027386279
-
Reduction of leukocyte and interleukin-1β concentrations in the synovial fluid of rheumatoid arthritis patients treated with methotrexate
-
62 Ranjeny T, Carroll GJ: Reduction of leukocyte and interleukin-1β concentrations in the synovial fluid of rheumatoid arthritis patients treated with methotrexate. Arthritis Rheum 1993, 36:1244-1252.
-
(1993)
Arthritis Rheum
, vol.36
, pp. 1244-1252
-
-
Ranjeny, T.1
Carroll, G.J.2
-
63
-
-
0028604305
-
Circulating concentrations and production of cytokines and soluble receptors in rheumatoid arthritis patients: Effects of a single dose methotrexate
-
63 Barrera P, Boerbooms AMT, Demacker PNM, et al: Circulating concentrations and production of cytokines and soluble receptors in rheumatoid arthritis patients: effects of a single dose methotrexate. Br J Rheumatol 1994, 33:1017-1024.
-
(1994)
Br J Rheumatol
, vol.33
, pp. 1017-1024
-
-
Barrera, P.1
Boerbooms, A.M.T.2
Demacker, P.N.M.3
-
64
-
-
0029740907
-
Interleukin 1 (IL-1) receptor antagonist, soluble tumor necrosis factor receptors, IL-1β and IL-8-markers of remission in rheumatoid arthritis during treatment with methotrexate
-
64 Seitz M, Loetscher P, Dewald B, et al: Interleukin 1 (IL-1) receptor antagonist, soluble tumor necrosis factor receptors, IL-1β and IL-8-markers of remission in rheumatoid arthritis during treatment with methotrexate. J Rheumatol 1996, 23:1512-1516.
-
(1996)
J Rheumatol
, vol.23
, pp. 1512-1516
-
-
Seitz, M.1
Loetscher, P.2
Dewald, B.3
-
65
-
-
0024420825
-
An assay for the detection of interleukin-1 synthesis inhibitors: Effects of antirheumatic drugs
-
65 Rordorf-Adam C, Lazdins J, Woods-Cook K, et al: An assay for the detection of interleukin-1 synthesis inhibitors: effects of antirheumatic drugs. Drugs Exp Clin Res 1989, 15:366-372.
-
(1989)
Drugs Exp Clin Res
, vol.15
, pp. 366-372
-
-
Rordorf-Adam, C.1
Lazdins, J.2
Woods-Cook, K.3
-
66
-
-
0026346448
-
The effect of slow-acting anti-rheumatic drugs (SAARDs) and combination of SAARDs on monokine production in vitro
-
66 Danis VA, Franic GM, Brooks PM: The effect of slow-acting anti-rheumatic drugs (SAARDs) and combination of SAARDs on monokine production in vitro. Drugs Exp Clin Res 1991, 17:549-554.
-
(1991)
Drugs Exp Clin Res
, vol.17
, pp. 549-554
-
-
Danis, V.A.1
Franic, G.M.2
Brooks, P.M.3
-
67
-
-
0030795025
-
In vitro modulation of cytokine, cytokine inhibitor, and prostaglandin E release from blood mononuclear cells and synovial fibroblasts by antirheumatic drugs
-
67 Seitz M, Loetscher P, Dewald B, et al: In vitro modulation of cytokine, cytokine inhibitor, and prostaglandin E release from blood mononuclear cells and synovial fibroblasts by antirheumatic drugs. J Rheumatol 1997, 24:1471-1476.
-
(1997)
J Rheumatol
, vol.24
, pp. 1471-1476
-
-
Seitz, M.1
Loetscher, P.2
Dewald, B.3
-
68
-
-
0024990529
-
The effect of antirheumatic drugs on interleukin 1 (IL-1) activity and IL-1 and IL-1 inhibitor production by human monocytes
-
68 Chang DM, Baptiste P, Schur PH: The effect of antirheumatic drugs on interleukin 1 (IL-1) activity and IL-1 and IL-1 inhibitor production by human monocytes. J Rheumatol 1990, 17:1148-1157.
-
(1990)
J Rheumatol
, vol.17
, pp. 1148-1157
-
-
Chang, D.M.1
Baptiste, P.2
Schur, P.H.3
-
69
-
-
0024554111
-
The effects of methotrexate on the production and activity of IL-1
-
69 Segal R, Mozes E, Yaron M, et al: The effects of methotrexate on the production and activity of IL-1. Arthritis Rheum 1989, 32:370-377.
-
(1989)
Arthritis Rheum
, vol.32
, pp. 370-377
-
-
Segal, R.1
Mozes, E.2
Yaron, M.3
-
70
-
-
0025695745
-
Rescue of interleukin-1 activity by leucovorin following inhibition by methotrexate in a murine in vitro system
-
70 Segal R, Yaron M, Tartakovsky B, et al: Rescue of interleukin-1 activity by leucovorin following inhibition by methotrexate in a murine in vitro system. Arthritis Rheum 1990, 33:1745-1748.
-
(1990)
Arthritis Rheum
, vol.33
, pp. 1745-1748
-
-
Segal, R.1
Yaron, M.2
Tartakovsky, B.3
-
71
-
-
84961490074
-
Mechanism of action of methotrexate: Experimental evidence that methotrexate blocks the binding of interleukin 1β to the interleukin 1 receptor on target cells
-
71 Brody M, Bohm I, Bauer R: Mechanism of action of methotrexate: experimental evidence that methotrexate blocks the binding of interleukin 1β to the interleukin 1 receptor on target cells. Eur J Clin Chem Clin Biochem 1993, 31:667-674.
-
(1993)
Eur J Clin Chem Clin Biochem
, vol.31
, pp. 667-674
-
-
Brody, M.1
Bohm, I.2
Bauer, R.3
-
72
-
-
0029157365
-
Methotrexate action in rheumatoid arthritis: Stimulation of cytokine inhibitor and inhibition of chemokine production by peripheral blood mononuclear cells
-
72 Seitz M, Loetscher P, Dewald B, et al: Methotrexate action in rheumatoid arthritis: stimulation of cytokine inhibitor and inhibition of chemokine production by peripheral blood mononuclear cells. Br J Rheumatol 1995, 34:602-609.
-
(1995)
Br J Rheumatol
, vol.34
, pp. 602-609
-
-
Seitz, M.1
Loetscher, P.2
Dewald, B.3
-
73
-
-
0031790420
-
Effects of methotrexate on differentiation of monocytes and production of cytokine inhibitors by monocytes
-
73 Seitz M, Zwicker M, Loetscher P: Effects of methotrexate on differentiation of monocytes and production of cytokine inhibitors by monocytes. Arthritis Rheum 1998, 41:2032-2038.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 2032-2038
-
-
Seitz, M.1
Zwicker, M.2
Loetscher, P.3
-
74
-
-
0028092007
-
Prostaglandin and tumor necrosis factor secretion by peritoneal macrophages isolated from normal and arthritic rats treated with liposomal methotrexate
-
74 Williams AS, Camilleri JP, Topley N, et al: Prostaglandin and tumor necrosis factor secretion by peritoneal macrophages isolated from normal and arthritic rats treated with liposomal methotrexate. J Pharmacol Toxicol Methods 1994, 32:53-58.
-
(1994)
J Pharmacol Toxicol Methods
, vol.32
, pp. 53-58
-
-
Williams, A.S.1
Camilleri, J.P.2
Topley, N.3
-
75
-
-
0028958509
-
The effect of liposomally conjugated methotrexate upon mediator release from human peripheral blood monocytes
-
75 Williams AS, Punn YL, Amos N, et al: The effect of liposomally conjugated methotrexate upon mediator release from human peripheral blood monocytes. Br J Rheumatol 1995, 34:241-245.
-
(1995)
Br J Rheumatol
, vol.34
, pp. 241-245
-
-
Williams, A.S.1
Punn, Y.L.2
Amos, N.3
-
76
-
-
0027952905
-
Effect of liposomally encapsulated MTX-DMPE conjugates upon TNFα and PGE2 release by lipopolysaccharide stimulated rat peritoneal macrophages
-
76 Williams AS, Topley N, Williams BD: Effect of liposomally encapsulated MTX-DMPE conjugates upon TNFα and PGE2 release by lipopolysaccharide stimulated rat peritoneal macrophages. Biochim Biophys Acta 1994, 1225:217-222.
-
(1994)
Biochim Biophys Acta
, vol.1225
, pp. 217-222
-
-
Williams, A.S.1
Topley, N.2
Williams, B.D.3
-
77
-
-
0026629739
-
Interleukin-8 in inflammatory rheumatic diseases: Synovial fluid levels, relation to rheumatoid factors, production by mononuclear cells, and effects of gold sodium thiomalate and methotrexate
-
77 Seitz M, Dewald B, Ceska M, et al: Interleukin-8 in inflammatory rheumatic diseases: synovial fluid levels, relation to rheumatoid factors, production by mononuclear cells, and effects of gold sodium thiomalate and methotrexate. Rheumatol Int 1992, 12:159-164.
-
(1992)
Rheumatol Int
, vol.12
, pp. 159-164
-
-
Seitz, M.1
Dewald, B.2
Ceska, M.3
-
78
-
-
0024419176
-
Inhibition of in vitro vascular endothelial cell proliferation and in vivo neovascularization by low-dose methotrexate
-
78 Hirata S, Matsubara T, Saura R, et al: Inhibition of in vitro vascular endothelial cell proliferation and in vivo neovascularization by low-dose methotrexate. Arthritis Rheum 1989, 32:1065-1073.
-
(1989)
Arthritis Rheum
, vol.32
, pp. 1065-1073
-
-
Hirata, S.1
Matsubara, T.2
Saura, R.3
-
79
-
-
0026348814
-
Angiogenesis and its inhibition: Potential new therapies in oncology and non-neopiastic diseases
-
79 Billington DC: Angiogenesis and its inhibition: potential new therapies in oncology and non-neopiastic diseases. Drug Des Discov 1991, 8:3-35.
-
(1991)
Drug Des Discov
, vol.8
, pp. 3-35
-
-
Billington, D.C.1
-
80
-
-
0027097806
-
Interleukin-8 as a macrophage-derived mediator of angiogenesis
-
80 Koch AE, Polverini PJ, Kunkel SL, et al: Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science 1992, 258:1898-1901.
-
(1992)
Science
, vol.258
, pp. 1898-1901
-
-
Koch, A.E.1
Polverini, P.J.2
Kunkel, S.L.3
-
81
-
-
0028197659
-
Interference of circulating azathioprine but not methotrexate or sulfasalazine with measurements of interleukin-6 bioactivity
-
81 Barrera P, Boerbooms AM, Sauerwein RW, et al: Interference of circulating azathioprine but not methotrexate or sulfasalazine with measurements of interleukin-6 bioactivity. Lymphokine Cytokine Res 1994, 13:155-159.
-
(1994)
Lymphokine Cytokine Res
, vol.13
, pp. 155-159
-
-
Barrera, P.1
Boerbooms, A.M.2
Sauerwein, R.W.3
-
82
-
-
0027201923
-
Circulating soluble tumor necrosis factor receptors, interleukin-2 receptors, tumor necrosis factor α, and interleukin-6 levels in rheumatoid arthritis: Longitudinal evaluation during methotrexate and azathioprine therapy
-
82 Barrera P, Boerbooms AMT, Janssen EM, et al: Circulating soluble tumor necrosis factor receptors, interleukin-2 receptors, tumor necrosis factor α, and interleukin-6 levels in rheumatoid arthritis: longitudinal evaluation during methotrexate and azathioprine therapy. Arthritis Rheum 1993, 36:1070-1079.
-
(1993)
Arthritis Rheum
, vol.36
, pp. 1070-1079
-
-
Barrera, P.1
Boerbooms, A.M.T.2
Janssen, E.M.3
-
83
-
-
0028924896
-
Interleukin 6 (IL-6) and IL-2 receptor levels in patients with rheumatoid arthritis treated with low-dose oral methotrexate
-
83 Crilly A, McIness JB, McDonald AG, et al: Interleukin 6 (IL-6) and IL-2 receptor levels in patients with rheumatoid arthritis treated with low-dose oral methotrexate. J Rheumatol 1995, 22:224-226.
-
(1995)
J Rheumatol
, vol.22
, pp. 224-226
-
-
Crilly, A.1
McIness, J.B.2
McDonald, A.G.3
-
84
-
-
0028903526
-
Circulating interleukin 10 and interleukin 6 serum levels in rheumatoid arthritis patients treated with methotrexate or gold salts: Preliminary report
-
84 Lacki JK, Klama K, Mackiewitz SH, et al: Circulating interleukin 10 and interleukin 6 serum levels in rheumatoid arthritis patients treated with methotrexate or gold salts: preliminary report. Inflammation Res 1995, 44:24-26.
-
(1995)
Inflammation Res
, vol.44
, pp. 24-26
-
-
Lacki, J.K.1
Klama, K.2
Mackiewitz, S.H.3
-
85
-
-
0028263362
-
Serum levels of interleukin-6 and tumor-necrosis-factor-alpha are not correlated to disease activity in patients with rheumatoid arthritis after treatment with low-dose methotrexate
-
85 Wascher TC, Hermann J, Brezineschek R, et al: Serum levels of interleukin-6 and tumor-necrosis-factor-alpha are not correlated to disease activity in patients with rheumatoid arthritis after treatment with low-dose methotrexate. Eur J Clin Invest 1994, 24:73-75.
-
(1994)
Eur J Clin Invest
, vol.24
, pp. 73-75
-
-
Wascher, T.C.1
Hermann, J.2
Brezineschek, R.3
-
86
-
-
0013602550
-
Stimulation of TIMP-1 production in patients with rheumatoid arthritis upon MTX treatment
-
86 Seitz M, Dayer J-M: Stimulation of TIMP-1 production in patients with rheumatoid arthritis upon MTX treatment [abstract]. Z Rheumatol 1998, 57(suppl 1):P122.
-
(1998)
Z Rheumatol
, vol.57
, Issue.SUPPL. 1
-
-
Seitz, M.1
Dayer, J.-M.2
|