메뉴 건너뛰기




Volumn 377, Issue 12, 1996, Pages 775-786

Mechanisms of nonhomologous DNA end-joining in frogs, mice and men

Author keywords

Cell extracts; DNA double strand breaks; DNA PK; DSB repair; Illegitimate recombination; Ligation

Indexed keywords

DNA; DOUBLE STRANDED DNA; EXONUCLEASE; PROTEIN KINASE;

EID: 0030475586     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/bchm3.1996.377.12.775     Document Type: Review
Times cited : (53)

References (50)
  • 2
    • 0021876991 scopus 로고
    • Enzymatic restriction of mammalian cell DNA: Evidence for the double-strand breaks as potentially lethal lesions
    • Bryant, P.E. (1985). Enzymatic restriction of mammalian cell DNA: evidence for the double-strand breaks as potentially lethal lesions. Int. J. Rad. Res. 48, 55-60.
    • (1985) Int. J. Rad. Res. , vol.48 , pp. 55-60
    • Bryant, P.E.1
  • 3
    • 0028020622 scopus 로고
    • Responses of radiosensitive repair-proficient cell lines to restriction endonucleases
    • Bryant, P.E., and Liu, N. (1994). Responses of radiosensitive repair-proficient cell lines to restriction endonucleases. Int. J. Rad. Res. 66, 597-601.
    • (1994) Int. J. Rad. Res. , vol.66 , pp. 597-601
    • Bryant, P.E.1    Liu, N.2
  • 4
    • 0024806056 scopus 로고
    • Oncogenic transformation of murine C3H 10T1/2 cells resulting from DNA double-strand breaks induced by a restriction endonuclease
    • Bryant, P.E., and Ritches, A.C. (1989). Oncogenic transformation of murine C3H 10T1/2 cells resulting from DNA double-strand breaks induced by a restriction endonuclease. Br. J. Cancer 60, 852-854.
    • (1989) Br. J. Cancer , vol.60 , pp. 852-854
    • Bryant, P.E.1    Ritches, A.C.2
  • 5
    • 0015208033 scopus 로고
    • Development of terminal deoxynucleotidyl transferase activity in embryonic calf thymus gland
    • Chang, L.M.S. (1971). Development of terminal deoxynucleotidyl transferase activity in embryonic calf thymus gland. Biochem. Biophys. Res. Commun. 44, 124-131.
    • (1971) Biochem. Biophys. Res. Commun. , vol.44 , pp. 124-131
    • Chang, L.M.S.1
  • 6
    • 0025737845 scopus 로고
    • DNA synthesis on discontinuous templates by DNA polymerase I of Escherichia coli
    • Clark, J.M. (1991). DNA synthesis on discontinuous templates by DNA polymerase I of Escherichia coli. Gene 104, 75-80.
    • (1991) Gene , vol.104 , pp. 75-80
    • Clark, J.M.1
  • 8
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam, J.D., Lebovitz, R.M., and Roeder, R.G. (1983). Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucl. Acids Res. 11, 1475-1489.
    • (1983) Nucl. Acids Res. , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 9
    • 0026657635 scopus 로고
    • Multiple components are involved in the efficient joining of double stranded DNA breaks in human cell extracts
    • Fairman, M.P., Johnson, A.P., and Thacker, J. (1992). Multiple components are involved in the efficient joining of double stranded DNA breaks in human cell extracts. Nucl. Acids Res. 20, 4145-4152.
    • (1992) Nucl. Acids Res. , vol.20 , pp. 4145-4152
    • Fairman, M.P.1    Johnson, A.P.2    Thacker, J.3
  • 10
    • 0028897304 scopus 로고
    • DNA-dependent protein kinase activity is absent in xrs-6 cells: Implications for site-specific recombination and DNA double-strand break repair
    • Finnie, N.J., Gottlieb, T.M., Blunt, T., Jeggo, P.A., and Jackson, S.P. (1995). DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair. Proc. Natl. Acad. Sci. USA 92, 320-324.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 320-324
    • Finnie, N.J.1    Gottlieb, T.M.2    Blunt, T.3    Jeggo, P.A.4    Jackson, S.P.5
  • 11
    • 0026492714 scopus 로고
    • V(D)J recombination gets a break
    • Gellert, M. (1992). V(D)J recombination gets a break. Trends Genet. 8, 408-412.
    • (1992) Trends Genet. , vol.8 , pp. 408-412
    • Gellert, M.1
  • 12
    • 0028287719 scopus 로고
    • Nonhomologous DNA end joining in Schizosaccharomyces pombe efficiently eliminates DNA double-strand-breaks from haploid sequences
    • Goedecke, W., Pfeiffer, P., and Vielmetter, W. (1994). Nonhomologous DNA end joining in Schizosaccharomyces pombe efficiently eliminates DNA double-strand-breaks from haploid sequences. Nucl. Acids Res. 22, 2094-2101.
    • (1994) Nucl. Acids Res. , vol.22 , pp. 2094-2101
    • Goedecke, W.1    Pfeiffer, P.2    Vielmetter, W.3
  • 13
    • 12644256775 scopus 로고
    • Double-strand break rejoining in extracts from eucaryotic cells
    • Congress Lectures, U. Hagen, D. Harder, H. Jung and C. Streffer, eds. (Würzburg: ICRR Society)
    • Göttlich, B., Daza, P., Reichenberger, S., Feldmann, E., and Pfeiffer, P. (1995). Double-strand break rejoining in extracts from eucaryotic cells. In: Radiation Research 1895-1995, Vol. 2, Congress Lectures, U. Hagen, D. Harder, H. Jung and C. Streffer, eds. (Würzburg: ICRR Society), pp. 372-375.
    • (1995) Radiation Research 1895-1995 , vol.2 , pp. 372-375
    • Göttlich, B.1    Daza, P.2    Reichenberger, S.3    Feldmann, E.4    Pfeiffer, P.5
  • 14
    • 0026303274 scopus 로고
    • The role of DNA double strand breaks in ionizing radiation-induced killing of eukaryotic cells
    • Iliakis, G. (1991). The role of DNA double strand breaks in ionizing radiation-induced killing of eukaryotic cells. Bioessays 13, 641-648.
    • (1991) Bioessays , vol.13 , pp. 641-648
    • Iliakis, G.1
  • 15
    • 0028791446 scopus 로고
    • DNA double-strand break repair and V(D)J-recombination: Involvement of DNA-PK
    • Jackson, S.P., and Jeggo, P.A. (1995). DNA double-strand break repair and V(D)J-recombination: involvement of DNA-PK. Trends Biol. Sci. 20, 412-415.
    • (1995) Trends Biol. Sci. , vol.20 , pp. 412-415
    • Jackson, S.P.1    Jeggo, P.A.2
  • 16
    • 0025368957 scopus 로고
    • Studies on mammalian mutants defective in rejoining double-strand breaks in DNA
    • Jeggo, P.A. (1990). Studies on mammalian mutants defective in rejoining double-strand breaks in DNA. Mut. Res. 239, 1-16.
    • (1990) Mut. Res. , vol.239 , pp. 1-16
    • Jeggo, P.A.1
  • 18
    • 0027375231 scopus 로고
    • Homologous and illegitimate recombination in developing Xenopus oocytes and eggs
    • Lehman, C.W., Clemens, M., Worthylake, D.K., Trautman, J.K., and Carroll, D. (1993). Homologous and illegitimate recombination in developing Xenopus oocytes and eggs. Mol. Cell. Biol. 13, 6897-6906.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6897-6906
    • Lehman, C.W.1    Clemens, M.2    Worthylake, D.K.3    Trautman, J.K.4    Carroll, D.5
  • 19
    • 0028352067 scopus 로고
    • Illegitimate recombination in Xenopus: Characterization of end-joined junctions
    • Lehman, C.W., Trautman, J.K., and Carroll, D. (1994). Illegitimate recombination in Xenopus: Characterization of end-joined junctions. Nucl. Acids Res. 22, 434-442.
    • (1994) Nucl. Acids Res. , vol.22 , pp. 434-442
    • Lehman, C.W.1    Trautman, J.K.2    Carroll, D.3
  • 20
    • 15844385545 scopus 로고    scopus 로고
    • Ku80-deficient cells exhibit excess degradation of extrachromosomal DNA
    • Liang, F., and Jasin, M. (1996). Ku80-deficient cells exhibit excess degradation of extrachromosomal DNA. J. Biol. Chem. 271, 14405-14411.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14405-14411
    • Liang, F.1    Jasin, M.2
  • 22
    • 0027502171 scopus 로고
    • Mechanisms involved in rejoining DNA double-strand breaks induced by ionizing radiation and restriction enzymes
    • Lutze, L.H., Cleaver, J.E., Morgan, W.F., and Winegar, R.A. (1993). Mechanisms involved in rejoining DNA double-strand breaks induced by ionizing radiation and restriction enzymes. Mut Res. 299, 225-232.
    • (1993) Mut Res. , vol.299 , pp. 225-232
    • Lutze, L.H.1    Cleaver, J.E.2    Morgan, W.F.3    Winegar, R.A.4
  • 23
    • 0001885636 scopus 로고
    • Illegitimate recombination in mammalian cells
    • D.E. Berg and M.M. Howe, eds., (Washington D.C.: American Society for Microbiology)
    • Meuth, M. (1989). Illegitimate recombination in mammalian cells. In: Mobile DNA, D.E. Berg and M.M. Howe, eds., (Washington D.C.: American Society for Microbiology), pp. 833-860.
    • (1989) Mobile DNA , pp. 833-860
    • Meuth, M.1
  • 24
    • 0025281682 scopus 로고
    • The structure of mutation in mammalian cells
    • Meuth, M. (1990). The structure of mutation in mammalian cells. Biochim. Biophys. Acta 1032, 1-17.
    • (1990) Biochim. Biophys. Acta , vol.1032 , pp. 1-17
    • Meuth, M.1
  • 25
    • 0024458459 scopus 로고
    • DNA sequence determination of γ-radiation-induced mutations of the hamster aprt locus
    • Miles, C., and Meuth, M. (1989: DNA sequence determination of γ-radiation-induced mutations of the hamster aprt locus. Mut Res. 227, 97-102.
    • (1989) Mut Res. , vol.227 , pp. 97-102
    • Miles, C.1    Meuth, M.2
  • 26
    • 0025769860 scopus 로고
    • End-joining of DNA fragments in adenovirus transfection of human cells
    • Munz, P.L., and Young, C.S.H. (1991). End-joining of DNA fragments in adenovirus transfection of human cells. Virology 183, 160-169.
    • (1991) Virology , vol.183 , pp. 160-169
    • Munz, P.L.1    Young, C.S.H.2
  • 27
    • 0021592929 scopus 로고
    • Molecular mechanisms involved in the production of chromosomal aberrations: III. Restriction endonucleases
    • Berlin
    • Natarajan, A.T., and Obe, G. (1984). Molecular mechanisms involved in the production of chromosomal aberrations: III. Restriction endonucleases. Chromosoma (Berlin), 90, 120-127.
    • (1984) Chromosoma , vol.90 , pp. 120-127
    • Natarajan, A.T.1    Obe, G.2
  • 28
    • 0028144408 scopus 로고
    • Characterization of DNA end joining in a mammalian cell nuclear extract: Junction formation is accompanied by nucleotide loss, which is limited and uniform but not site specific
    • Nicolás, A.L., and Young, C.S.H. (1994). Characterization of DNA end joining in a mammalian cell nuclear extract: junction formation is accompanied by nucleotide loss, which is limited and uniform but not site specific. Mol. Cell. Biol. 14, 170-180.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 170-180
    • Nicolás, A.L.1    Young, C.S.H.2
  • 29
    • 0028921338 scopus 로고
    • A modified single-strand annealing model best explains the joining of DNA double-strand breaks in mammalian cells and cell extracts
    • Nicolás, A.L., Munz, P.L., and Young, C.S.H. (1995). A modified single-strand annealing model best explains the joining of DNA double-strand breaks in mammalian cells and cell extracts. Nucl. Acids Res. 23, 1036-1043.
    • (1995) Nucl. Acids Res. , vol.23 , pp. 1036-1043
    • Nicolás, A.L.1    Munz, P.L.2    Young, C.S.H.3
  • 30
    • 0025151450 scopus 로고
    • The rejoining of double-strand breaks in DNA by human cell extracts
    • North, P., Ganesh, A., and Thacker, J. (1990). The rejoining of double-strand breaks in DNA by human cell extracts. Nucl. Acids Res. 18, 6205-6210.
    • (1990) Nucl. Acids Res. , vol.18 , pp. 6205-6210
    • North, P.1    Ganesh, A.2    Thacker, J.3
  • 31
    • 0024284051 scopus 로고
    • Joining of nonhomologous DNA double-strand-breaks in vitro
    • Pfeiffer, P., and Vielmetter, W. (1988). Joining of nonhomologous DNA double-strand-breaks in vitro. Nucl. Acids Res. 16, 907-924.
    • (1988) Nucl. Acids Res. , vol.16 , pp. 907-924
    • Pfeiffer, P.1    Vielmetter, W.2
  • 32
  • 33
    • 0028078579 scopus 로고
    • Mechanisms of overlap formation in nonhomologous DNA end joining
    • Pfeiffer, P., Thode, S., Hancke, J., and Vielmetter, W. (1994b). Mechanisms of overlap formation in nonhomologous DNA end joining. Mol. Cell. Biol. 14, 888-895.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 888-895
    • Pfeiffer, P.1    Thode, S.2    Hancke, J.3    Vielmetter, W.4
  • 34
    • 0028065121 scopus 로고
    • Illegitimate recombination induced by DNA double-strand breaks in a mammalian chromosome
    • Phillips, J.W., and Morgan, W.F. (1994). Illegitimate recombination induced by DNA double-strand breaks in a mammalian chromosome. Mol. Cell. Biol. 14, 5794-5803.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5794-5803
    • Phillips, J.W.1    Morgan, W.F.2
  • 35
    • 0024434992 scopus 로고
    • Neoplastic transformation of human epithelial cells in vitro
    • Rhim, J.S. (1989). Neoplastic transformation of human epithelial cells in vitro. Anticancer Res. 9, 1345-1366.
    • (1989) Anticancer Res. , vol.9 , pp. 1345-1366
    • Rhim, J.S.1
  • 36
    • 0022976432 scopus 로고
    • Nonhomologous recombination in mammalian cells: Role for short sequence homologies in the joining reaction
    • Roth, D.B., and Wilson, J.H. (1986). Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction. Mol. Cell. Biol. 6, 4295-4304.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 4295-4304
    • Roth, D.B.1    Wilson, J.H.2
  • 37
    • 0002895728 scopus 로고
    • Illegitimate recombination in mammalian cells
    • R. Kucherlapati and G. Smith (eds.), (Washington, D.C.; USA: American Society for Microbiology)
    • Roth, D.B., and Wilson, J.H. (1988). Illegitimate recombination in mammalian cells. In: Genetic Recombination, R. Kucherlapati and G. Smith (eds.), (Washington, D.C.; USA: American Society for Microbiology), pp. 621-653.
    • (1988) Genetic Recombination , pp. 621-653
    • Roth, D.B.1    Wilson, J.H.2
  • 38
    • 0022256461 scopus 로고
    • Mechanisms of nonhomologous recombination of mammalian cells
    • Roth, D.B., Porter, T.N., and Wilson, J.H. (1985). Mechanisms of nonhomologous recombination of mammalian cells. Mol. Cell. Biol. 5, 2599-2607.
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 2599-2607
    • Roth, D.B.1    Porter, T.N.2    Wilson, J.H.3
  • 39
    • 0027401319 scopus 로고
    • Use of the DNA end joining activity of a Xenopus laevis egg extract for construction of deletion and expression vectors for HIV-1 Tat and Rev proteins
    • Schaal, H., Pfeiffer, P., Klein, M., Gehrmann, P., and Scheid, A. (1993). Use of the DNA end joining activity of a Xenopus laevis egg extract for construction of deletion and expression vectors for HIV-1 Tat and Rev proteins. Gene 124, 275-280.
    • (1993) Gene , vol.124 , pp. 275-280
    • Schaal, H.1    Pfeiffer, P.2    Klein, M.3    Gehrmann, P.4    Scheid, A.5
  • 41
    • 0020541955 scopus 로고
    • The double-strand-break repair model for recombination
    • Szostak, J.W., Orr-Weaver, T.-L., Rothstein, R., and Stahl, F.W. (1983). The double-strand-break repair model for recombination. Cell 33, 25-35.
    • (1983) Cell , vol.33 , pp. 25-35
    • Szostak, J.W.1    Orr-Weaver, T.-L.2    Rothstein, R.3    Stahl, F.W.4
  • 42
    • 0027074470 scopus 로고
    • A mechanism for deletion formation in DNA by human cell extracts: The involvement of short sequence repeats
    • Thacker, J., Chalk, J., Ganesh, A., and North, P. (1992). A mechanism for deletion formation in DNA by human cell extracts: the involvement of short sequence repeats. Nucl. Acids Res. 20, 6183-6188.
    • (1992) Nucl. Acids Res. , vol.20 , pp. 6183-6188
    • Thacker, J.1    Chalk, J.2    Ganesh, A.3    North, P.4
  • 43
    • 0025274315 scopus 로고
    • A novel pathway of DNA end-to-end joining
    • Thode, S., Schäfer, A., Pfeiffer, P., and Vielmetter, W. (1990). A novel pathway of DNA end-to-end joining. Cell 60, 921-928.
    • (1990) Cell , vol.60 , pp. 921-928
    • Thode, S.1    Schäfer, A.2    Pfeiffer, P.3    Vielmetter, W.4
  • 44
    • 0024195429 scopus 로고
    • DNA damage produced by ionizing radiation in mammalian cells: Identities, Mechanisms of formation, and reparability
    • Ward, J.F. (1988). DNA damage produced by ionizing radiation in mammalian cells: identities, Mechanisms of formation, and reparability. Progr. Nucl. Acids Res. Mol. Biol. 35, 95-125.
    • (1988) Progr. Nucl. Acids Res. Mol. Biol. , vol.35 , pp. 95-125
    • Ward, J.F.1
  • 45
    • 0029117310 scopus 로고
    • What to do at an end: DNA double-strand break repair
    • Weaver, D.T. (1995). What to do at an end: DNA double-strand break repair. Trends Genet. 11, 388-392.
    • (1995) Trends Genet. , vol.11 , pp. 388-392
    • Weaver, D.T.1
  • 46
    • 0026446383 scopus 로고
    • Spectrum of mutations produced by specific types of restriction enzyme induced double-strand breaks
    • Winegar, R.A., Lutze, L.H., Rufer, J.T., and Morgan, W.F. (1992). Spectrum of mutations produced by specific types of restriction enzyme induced double-strand breaks. Mutagenesis 7, 439-445.
    • (1992) Mutagenesis , vol.7 , pp. 439-445
    • Winegar, R.A.1    Lutze, L.H.2    Rufer, J.T.3    Morgan, W.F.4
  • 47
    • 0023878893 scopus 로고
    • Complementation of Xeroderma pigmentosum DNA repair defect in cell-free extracts
    • Wood, R.D., Robins, P., and Lidahl, T. (1988). Complementation of Xeroderma pigmentosum DNA repair defect in cell-free extracts. Cell 53, 97-106.
    • (1988) Cell , vol.53 , pp. 97-106
    • Wood, R.D.1    Robins, P.2    Lidahl, T.3
  • 48
    • 0344205503 scopus 로고
    • Molecular lesions important for neoplastic cell transformation of mouse (C3H10T1/2) and human epithelial cells by ionizing radiation
    • K.H. Chadwick, C. Seymour and B. Barnhart, eds., (Bristol, UK: Adam Hilger)
    • Yang, T.C., Craise, L.M., and Tobias, C.A. (1989). Molecular lesions important for neoplastic cell transformation of mouse (C3H10T1/2) and human epithelial cells by ionizing radiation. In: Cell Transformation and Radiation-Induced Cancer. K.H. Chadwick, C. Seymour and B. Barnhart, eds., (Bristol, UK: Adam Hilger), pp. 301-308.
    • (1989) Cell Transformation and Radiation-Induced Cancer , pp. 301-308
    • Yang, T.C.1    Craise, L.M.2    Tobias, C.A.3
  • 49
    • 0027448457 scopus 로고
    • Nonhomologous DNA end joining in chromosomal aberration formation
    • Yates, B.L., and Morgan, W.F. (1993). Nonhomologous DNA end joining in chromosomal aberration formation. Mut. Res. 285, 53-60.
    • (1993) Mut. Res. , vol.285 , pp. 53-60
    • Yates, B.L.1    Morgan, W.F.2
  • 50
    • 0030576534 scopus 로고    scopus 로고
    • Ku86-deficient mice exhibit severe combined immunodeficiency and defective V(D)J recombination intermediates
    • Zhu, C., Bogue, M.A., Lim, D.-S., Hasty, P., and Roth, D.B. (1996). Ku86-deficient mice exhibit severe combined immunodeficiency and defective V(D)J recombination intermediates. Cell 86, 379-389.
    • (1996) Cell , vol.86 , pp. 379-389
    • Zhu, C.1    Bogue, M.A.2    Lim, D.-S.3    Hasty, P.4    Roth, D.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.