A novel T cell cytokine stimulates interleukin-6 in human osteoblastic cells

Journal of Bone and Mineral Research

Volumn 14, Issue 7, 1999, Pages 1096-1103

  Rifas, Leonard ^a,b   Avioli, Louis V ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BARNES JEWISH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANTIBODY PRODUCTION; ARTICLE; AUTOIMMUNITY; BONE ATROPHY; BONE MASS; CELL INTERACTION; CELL STIMULATION; HUMAN; HUMAN CELL; LYMPHOCYTIC INFILTRATION; MEMORY CELL; OSTEOBLAST; RHEUMATOID ARTHRITIS; STEM CELL; T LYMPHOCYTE ACTIVATION;

ANTIBODIES; ANTIGENS, CD; BLOTTING, NORTHERN; CELLS, CULTURED; COCULTURE TECHNIQUES; CULTURE MEDIA, CONDITIONED; CYCLOSPORINE; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INTERLEUKIN-17; INTERLEUKIN-6; LYMPHOCYTE ACTIVATION; OSTEOBLASTS; RNA, MESSENGER; T-LYMPHOCYTES;

EID: 0032970716     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1999.14.7.1096     Document Type: Article

References (50)

1. Barwell R 1865 Diseases of the Joints. Hardwicke, London, U.K.
2. Deodhar AA, Woolf AD 1996 Bone mass measurement and bone metabolism in rheumatoid arthritis: A review. Br J Rheumatol 35:309-322.
3. Dequeker J, Maenaut K, Verwilghen J, Westhovens R 1995 Osteoporosis in rheumatoid arthritis. Clin Exp Rheumatol 13 (Suppl 12):S21-S26.
4. Star VL, Hochberg MC 1994 Osteoporosis in patients with rheumatic diseases. Rheum Dis Clin North Am 20:561-576.
5. Gough AK, Lilley J, Eyre S, Holder RL, Emery P 1994 Generalized bone loss in patients with early rheumatoid arthritis. Lancet 344:23-27.
6. Jones SM, Bhalla AK 1993 Osteoporosis in rheumatoid arthritis. Clin Exp Rheumatol 11:557-562.
7. Kinne RW, Palombo-Kinne E, Emmrich F 1997 T-cells in the pathogenesis of rheumatoid arthritis: Villains or accomplices? Biochim Biophys Acta 1360:109-141.
8. Weyand CM, Goronzy JJ 1997 Pathogenesis of rheumatoid arthritis. Med Clin North Am 81:29-55.
9. Wagner S, Fritz P, Einsele H, Sell S, Saal JG 1997 Evaluation of synovial cytokine patterns in rheumatoid arthritis and osteoarthritis by quantitative reverse transcription polymerase chain reaction. Rheumatol Int 16:191-196.
10. Okamoto H, Yamamura M, Morita Y, Harada S, Makino H, Ota Z 1997 The synovial expression and serum levels of interleukin-6, interleukin-11, leukemia inhibitory factor, and oncostatin M in rheumatoid arthritis. Arthritis Rheum 40:1096-1105.
11. Gough AK, Peel NF, Eastell R, Holder RL, Lilley J, Emery P 1994 Excretion of pyridinium crosslinks correlates with disease activity and appendicular bone loss in early rheumatoid arthritis. Ann Rheum Dis 53:14-17.
12. Hansen M, Florescu A, Stoltenberg M, Podenphant J, Pedersen-Zbinden B, Horslev-Petersen K, Hyldstrup L, Lorenzen I 1996 Bone loss in rheumatoid arthritis: Influence of disease activity, duration of the disease, functional capacity, and corticosteroid treatment. Scand J Rheumatol 25:367-376.
13. Buchinsky FJ, Ma Y, Mann GN, Rucinski B, Bryer HP, Romero DF, Jee WS, Epstein S 1996 T lymphocytes play a critical role in the development of cyclosporin A-induced osteopenia. Endocrinology 137:2278-2285.
14. Schlosberg M, Movsowitz C, Epstein S, Ismail F, Fallon MD, Thomas S 1989 The effect of cyclosporin A administration and its withdrawal on bone mineral metabolism in the rat. Endocrinology 124:2179-2184.
15. Movsowitz C, Epstein S, Fallon M, Ismail F, Thomas S 1988 Cyclosporin-A in vivo produces severe osteopenia in the rat: Effect of dose and duration of administration. Endocrinology 123:2571-2577.
16. Arinbjarnarson S, Jonsson T, Steinsson K, Sigfusson A, Jonsson H, Geirsson A, Thorsteinsson J, Valdimarsson H 1997 IgA rheumatoid factor correlates with changes in B and T lymphocyte subsets and disease manifestations in rheumatoid arthritis. J Rheumatol 24:269-274.
17. Sfikakis PP, Zografou A, Viglis V, Iniotaki-Theodoraki A, Piskontaki I, Tsokos GC, Sfikakis P, Choremi-Papadopoulou H 1995 CD28 expression on T cell subsets in vivo and CD28-mediated T cell response in vitro in patients with rheumatoid arthritis. Arthritis Rheum 38:649-654.
18. Abbas AK, Murphy KM, Sher A 1996 Functional diversity of helper T lymphocytes. Nature 383:787-793.
19. Wechsler AS, Gordon MC, Dendorfer U, LeClair KP 1994 Induction of IL-8 expression in T cells uses the CD28 costimulatory pathway. J Immunol 153:2515-2523.
20. Yao Z, Painter SL, Fanslow WC, Ulrich D, Macduff BM, Spriggs MK, Armitage RJ 1995 Human IL-17: A novel cytokine derived from T cells. J Immunol 155:5483-5486.
21. John V, Hock JM, Short LL, Glasebrook AL, Galvin RJ 1996 A role for CD8+ T lymphocytes in osteoclast differentiation in vitro. Endocrinology 137:2457-2463.
22. Bertolini DR, Nedwin GE, Bringman TS, Smith DD, Mundy GR 1986 Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors. Nature 319:516-518.
23. Kurihara N, Bertolini D, Suda T, Akiyama Y, Roodman GD 1990IL-6 stimulates osteoclast-like multinucleated cell formation in long term human marrow cultures by inducing IL-1 release. J Immunol 144:4226-4230.
24. Quesniaux VF 1993 Immunosuppressants: tools to investigate the physiological role of cytokines. BioEssays 15:731-739.
25. Ho S, Clipstone N, Timmermann L, Northrop J, Graef I, Fiorentino D, Nourse J, Crabtree GR 1996 The mechanism of action of cyclosporin A and FK506. Clin Immunol Immunopathol 80:S40-S45.
26. Walsh CT, Zydowsky LD, McKeon FD 1992 Cyclosporin A, the cyclophilin class of peptidylprolyl isomerases, and blockade of T cell signal transduction. J Biol Chem 267:13115-13118.
27. McCaffrey PG, Goldfeld AE, Rao A 1994 The role of NFATp in cyclosporin A-sensitive tumor necrosis factor-alpha gene transcription. J Biol Chem 269:30445-30450.
28. Bentin J 1995 Mechanism of action of cyclosporin in rheumatoid arthritis. Clin Rheumatol 14 (Suppl 2):22-25.
29. Dougados M 1994 Cyclosporin in rheumatoid arthritis. Clin Exp Rheumatol 12 (Suppl 11):S75-S78.
30. Yocum D 1993 Immunological actions of cyclosporin A in rheumatoid arthritis. Br J Rheumatol 32 (Suppl 1):38-41.
31. Rifas L, Fausto A, Scott MJ, Avioli LV, Welgus HG 1994 Expression of metalloproteinases and tissue inhibitors of metalloproteinases in human osteoblast-like cells: Differentiation is associated with repression of metalloproteinase biosynthesis. Endocrinology 134:213-221.
32. Rifas L, Kenney JS, Marcelli M, Pacifici R, Cheng SL, Dawson LL, Avioli LV 1995 Production of interleukin-6 in human osteoblasts and human bone marrow stromal cells: evidence that induction by interleukin-1 and tumor necrosis factor-alpha is not regulated by ovarian steroids. Endocrinology 136:4056-4067.
33. Rifas L, Halstead LR, Peck WA, Avioli LV, Welgus HG 1989 Human osteoblasts in vitro secrete tissue inhibitor of metalloproteinases and gelatinase but not interstitial collagenase as major cellular products. J Clin Invest 84:686-694.
34. Chaudhary LR, Avioli LV 1994 Dexamethasone regulates IL-1 beta and TNF-alpha-induced interleukin-8 production in human bone marrow stromal and osteoblast-like cells. Calcif Tissue Int 55:16-20.
35. Chaudhary LR, Cheng SL, Avioli LV 1996 Induction of early growth response-1 gene by interleukin-1 beta and tumor necrosis factor-alpha in normal human bone marrow stromal an osteoblastic cells: Regulation by a protein kinase C inhibitor. Mol Cell Biochem 156:69-77.
36. Kimoto S, Cheng SL, Zhang SF, Avioli LV 1994 The effect of glucocorticoid on the synthesis of biglycan and decorin in human osteoblasts and bone marrow stromal cells. Endocrinology 135:2423-2431.
37. Cheng SL, Lecanda F, Davidson MK, Warlow PM, Zhang SF, Zhang L, Suzuki S, St. John T, Civitelli R 1998 Human osteoblasts express a repertoire of cadherins, which are critical for BMP-2-induced osteogenic differentiation. J Bone Miner Res 13:633-644.
38. May LT, Helfgott DC, Sehgal PB 1986 Anti-beta-interferon antibodies inhibit the increased expression of HLA-B7 mRNA in tumor necrosis factor-treated human fibroblasts: Structural studies of the beta 2 interferon involved. Proc Natl Acad Sci USA 83:8957-8961.
39. Fossiez F, Djossou O, Chomarat P, Flores-Romo L, Ait-Yahia S, Maat C, Pin JJ, Garrone P, Garcia E, Saeland S, Blanchard D, Gaillard C, Das Mahapatra B, Rouvier E, Golstein P, Banchereau J, Lebecque S 1996 T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J Exp Med 183:2593-2603.
40. Maini RN, Elliott M, Brennan FM, Williams RO, Feldmann M 1997 TNF blockade in rheumatoid arthritis: Implications for therapy and pathogenesis. APMIS 105:257-263.
41. Linsley PS, Ledbetter JA 1993 The role of the CD28 receptor during T cell responses to antigen. Annu Rev Immunol 11:191-212.
42. Ledbetter JA, Imboden JB, Schieven GL, Grosmaire LS, Rabinovitch PS, Lindsten T, Thompson CB, June CH 1990 CD28 ligation in T-cell activation: Evidence for two signal transduction pathways. Blood 75:1531-1539.
43. Thompson CB, Lindsten T, Ledbetter JA, Kunkel SL, Young HA, Emerson SG, Leiden JM, June CH 1989 CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines. Proc Natl Acad Sci USA 86:1333-1337.
44. June CH, Ledbetter JA, Gillespie MM, Lindsten T, Thompson CB 1987 T-cell proliferation involving the CD28 pathway is associated with cyclosporine-resistant interleukin 2 gene expression. Mol Cell Biol 7:4472-4481.
45. Webb LM, Walmsley MJ, Feldmann M 1996 Prevention and amelioration of collagen-induced arthritis by blockade of the CD28 co-stimulatory pathway: Requirement for both B7-1 and B7-2. Eur J Immunol 26:2320-2328.
46. Liu MF, Kohsaka H, Sakurai H, Azuma M, Okumura K, Saito I, Miyasaka N 1996 The presence of costimulatory molecules CD86 and CD28 in rheumatoid arthritis synovium. Arthritis Rheum 39:110-114.
47. Verwilghen J, Corrigall V, Pope RM, Rodrigues R, Panayi GS 1993 Expression and function of CD5 and CD28 in patients with rheumatoid arthritis. Immunology 80:96-102.
48. Schmidt D, Goronzy JJ, Weyand CM 1996 CD4+ CD7- CD28-T cells are expanded in rheumatoid arthritis and are characterized by autoreactivity. J Clin Invest 97:2027-2037.
49. Tanaka Y, Morimoto I, Nakano Y, Okada Y, Hirota S, Nomura S, Nakamura T, Eto S 1995 Osteoblasts are regulated by the cellular adhesion through ICAM-1 and VCAM-1. J Bone Miner Res 10:1462-1469.
50. Harada Y, Watanabe S, Yssel H, Arai K 1996 Factors affecting the cytokine production of human T cells stimulated by different modes of activation. J Allergy Clin Immunol 98:S161.