Human osteoblasts express a repertoire of cadherins, which are critical for BMP-2-induced osteogenic differentiation

Journal of Bone and Mineral Research

Volumn 13, Issue 4, 1998, Pages 633-644

  Cheng, S U L I ^a   Lecanda, Fernando ^a   Davidson, Mari K ^a,b   Warlow, Pamela M ^c   Zhang, Shu Fang ^a   Zhang, Liming ^a   Suzuki, Shintaro ^d   John, Tom S T ^e   Civitelli, Roberto ^a,f  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Span Mistry of Educ and Science ^*

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d DOHENY EYE INSTITUTE   (United States)

^e ELI LILLY AND COMPANY   (United States)

^f Division of Bone and Mineral Diseases   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN; CADHERIN; MESSENGER RNA;

ARTICLE; BLAST TRANSFORMATION; BONE DEVELOPMENT; CANCER CELL CULTURE; CELL ADHESION; CELL DIFFERENTIATION; CELL INTERACTION; HUMAN; HUMAN CELL; OSTEOBLAST; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRABECULAR BONE;

BETA CATENIN; BONE MORPHOGENETIC PROTEINS; CADHERINS; CELL ADHESION; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL LINE, TRANSFORMED; CELLS, CULTURED; CYTOSKELETAL PROTEINS; HUMANS; OSTEOBLASTS; OSTEOSARCOMA; POLYMERASE CHAIN REACTION; RNA, MESSENGER; STEM CELLS; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0031977102     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1998.13.4.633     Document Type: Article

References (48)

1. Albelda SM, Buch CA 1990 Integrins and other cell adhesion molecules. FASEB J 4:2868-2880.
2. Takeichi M 1991 Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251:1451-1455.
3. Fish EM, Molitoris BA 1994 Alterations in epithelial polarity and the pathogenesis of disease states. N Engl J Med 330: 1580-1588.
4. Raisz LG, Rodan GA 1990 Cellular basis of bone turnover. In: Avioli LV, Krane SM (eds.) Metabolic Bone Diseases and Clinically Related Disorders, 2nd Ed. WB Saunders Co., Philadelphia, PA, U.S.A., pp. 1-41.
5. Palumbo C, Palazzini S, Marotti G 1990 Morphological study of intercellular junctions during osteocyte differentiation. Bone 11:401-406.
6. Doty SB 1981 Morphological evidence of gap junctions between bone cells. Calcif Tissue Int 33:509-511.
7. Kemler R 1992 Classical cadherins. Semin Cell Biol 3:149-155.
8. Suzuki S, Sano K, Tanihara H 1991 Diversity of the cadherin family: Evidence for eight new cadherins in nervous tissue. Cell Reg 2:261-270.
9. Tanihara H, Sano K, Heimark RL, St.John T, Suzuki S 1994 Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin. Cell Adhes Commun 2:15-26.
10. Okazaki M, Takeshita S, Kawai S, Kikuno R, Tsujimura A, Kudo A, Amann E 1994 Molecular cloning and characterization of OB-cadherin, a new member of cadherin family expressed in osteoblasts. J Biol Chem 269:12092-12098.
11. Kunth K, Becker KF, Atkinson MJ 1993 CD44 and cadherin adhesion molecules are expressed in osteoblasts. Calcif Tissue Int 52:S41 (abstract).
12. Suva LJ, Towler DA, Harada S, LaFage M-H, Stueckle SM, Rosenblatt M 1994 Hormonal regulation of osteoblast-derived cadherin expression in vitro and in vivo. J Bone Miner Res 9:S123 (abstract).
13. Tanihara H, Kido M, Obata S, Heimark RL, Davidson M, St.John T, Suzuki S 1994 Characterization of cadherin-4 and cadherin-5 reveals new aspects of cadherins. J Cell Sci 107: 1697-1704.
14. Merrifield RB 1963 Solid phase peptide synthesis I: The synthesis of a tetrapeptide. J Am Chem Soc 85:2149-2154.
15. Merrifield RB 1986 Solid phase synthesis. Science 232:341-347.
16. Gehron Robey P, Termine JD 1985 Human bone cells in vitro. Calcif Tissue Int 37:453-460.
17. Rifas L, Halstead LR, Peck WA, Avioli LV, Welgus HG 1989 Human osteoblasts in vitro secrete tissue inhibitor of metalloproteinases and gelatinase but not interstitial collagenase as major cellular products. J Clin Invest 84:686-694.
18. Cheng S-L, Yang JW, Rifas L, Zhang S-F, Avioli LV 1994 Differentiation of human bone marrow osteogenic stromal cells in vitro: Induction of the osteoblast phenotype by dexamethasone. Endocrinology 134:277-286.
19. Lecanda F, Avioli LV, Cheng S-L 1997 Regulation of bone matrix expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein-2. J Cell Biochem 67:386-398.
20. Shupnik MA, Tashjian AH Jr 1982 Epidermal growth factor and phorbol ester action on human osteosarcoma cells: Characterization of responsive and nonresponsive cell lines. J Biol Chem 257:12161-12164.
21. Lajeunesse D, Frondoza C, Schoffield B, Sacktor B 1990 Osteocalcin secretion by the human osteosarcoma cell line MG-63. J Bone Miner Res 5:915-922.
22. Rifas L, Fausto A, Scott MJ, Avioli LV, Welgus HG 1994 Expression of metalloproteinases and tissue inhibitors of metalloproteinases in human osteoblast-like cells: Differentiation is associated with repression of metalloproteinase biosynthesis. Endocrinology 134:213-221.
23. McClay DR, Wessel GM, Marchase RB 1981 Intercellular recognition: Quantitation of initial binding events. Proc Natl Acad Sci USA 78:4975-4979.
24. Angres B, Barth A, Nelson WJ 1996 Mechanism for transition from initial to stable cell-cell adhesion: Kinetic analysis of E-cadherin-mediated adhesion using a quantitative adhesion assay. J Cell Biol 134:549-557.
25. Koval M, Geist ST, Westphale EM, Kemendy AE, Civitelli R, Beyer EC, Steinberg TH 1995 Transfected connexin45 alters gap junction permeability in cells expressing endogenous connexin43. J Cell Biol 130:987-995.
26. 2+-dependent cell-cell adhesion molecule in endothelial cells. J Cell Biol 110:1745-1756.
27. Cheng S-L, Zhang S-F, Nelson TL, Warlow PM, Civitelli R 1994 Stimulation of human osteoblast differentiation and function by ipriflavone and its metabolites. Calcif Tissue Int 55: 356-362.
28. Sanger F, Nicklen S, Coulson AR 1977 DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74:5463-5467.
29. Babich M, Foti RP 1994 E-cadherins identified in osteoblastic cells: Effects of parathyroid hormone and extracellular calcium on localization. Life Sci 54:201-208.
30. Mbalaviele G, Nishimura R, Reddy R, Roodman GD, Mundy GR, Yoneda T 1996 Characterization of the molecular mechanism of heterotypic osteoblast-osteoclast interactions during bone resorption: Role of a novel cadherin-6 isoform. J Bone Miner Res 11:S112 (abstract).
31. Ozawa M, Baribault H, Kemler R 1989 The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. EMBO J 8:1711-1717.
32. Nagafuchi A, Ishihara S, Tsukita S 1994 The roles of catenins in the cadherin-mediated cell adhesion: Functional analysis of E-cadherin-β-catenin fusion molecules. J Cell Biol 127:235-245.
33. Behrens J, von Kries JP, Kuhl M, Bruhn L, Wedlich D, Grosschedl R, Birchmeier W 1996 Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 382:638-642.
34. van Molenaar M, de Wetering M, Oosterwegel M, Peterson-Maduro J, Godsave S, Korinek V, Roose J, Destree O, Clevers H 1996 XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. Cell 86:391-399.
35. Mege RM, Goudou D, Diaz C, Nicolet M, Garcia L, Geraud G, Rieger F 1992 N-cadherin and N-CAM in myoblast fusion: Compared localization and effect of blockade by peptides and antibodies. J Cell Sci 103:897-906.
36. Mbalaviele G, Chen H, Boyce BF, Mundy GR, Yoneda T 1995 The role of cadherin in the generation of multinucleated osteoclasts from mononuclear precursors in murine marrow. J Clin Invest 95:2757-2765.
37. Kimura Y, Matsunami H, Inoue T, Shimamura K, Uchida N, Ueno T, Miyazaki T, Takeichi M 1995 Cadherin-11 expressed in association with mesenchymal morphogenesis in the head, somite, and limb bud of early mouse embryos. Dev Biol 169: 347-358.
38. Hoffmann I, Balling R 1995 Cloning and expression analysis of a novel mesodermally expressed cadherin. Dev Biol 169:337-346.
39. Yamaguchi A, Katagiri T, Ikeda T, Wozney JM, Rosen V, Wang EA, Kahn AJ, Suda T, Yoshiki S 1991 Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro. J Cell Biol 113:681-687.
40. Hutton JC, Christofori G, Chi WY, Edman U, Guest PC, Hanahan D, Kelly RB 1993 Molecular cloning of mouse pancreatic islet R-cadherin: Differential expression in endocrine and exocrine tissue. Mol Endocrinol 7:1151-1160.
41. Inuzuka H, Redies C, Takeichi M 1991 Differential expression of R- and N-cadherin in neural and mesodermal tissues during early chicken development. Development 113:959-967.
42. Blaschuk OW, Pouliot Y, Holland PC 1990 Identification of a conserved region common to cadherins and influenza strain A hemagglutinins. J Mol Biol 211:679-682.
43. Udagawa N, Takahashi N, Akatsu T, Sasaki T, Yamaguchi A, Kodama H, Martin TJ, Suda T 1989 The bone marrow-derived stromal cell lines MC3T3-G2, PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cells. Endocrinology 125:1805-1813.
44. Wesolowski G, Duong LT, Lakkakorpi PT, Nagy RM, Tezuka K, Tanaka H, Rodan GA, Rodan SB 1995 Isolation and characterization of highly enriched, prefusion mouse osteoclastic cells. Exp Cell Res 219:679-686.
45. Civitelli R, Beyer EC, Warlow PM, Robertson AJ, Geist ST, Steinberg TH 1993 Connexin43 mediates direct intercellular communication in human osteoblastic cell networks. J Clin Invest 91:1888-1896.
46. Yamaguchi DT, Ma D, Lee A, Huang JT, Gruber HE 1994 Isolation and characterization of gap junctions in the osteoblastic MC3T3-E1, cell line. J Bone Miner Res 9:791-803.
47. 2+ in mouse epidermal cells is controlled by cadherin. J Cell Biol 114:545-555.
48. Meyer RA, Laird DW, Revel J-P, Johnson RG 1992 Inhibition of gap junction and adherens junction assembly by connexin and A-CAM antibodies. J Cell Biol 119:179-189.