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Volumn 30, Issue 3, 1999, Pages 536-550

Antiviral chemotherapy for chronic hepatitis B infection: Lessons learned from treating HIV-infected patients

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; AMPRENAVIR; DELAVIRDINE; DIDANOSINE; EFAVIRENZ; INDINAVIR; LAMIVUDINE; NELFINAVIR; NEVIRAPINE; NUCLEOSIDE ANALOG; RITONAVIR; SAQUINAVIR; STAVUDINE; ZALCITABINE; ZIDOVUDINE;

EID: 0032956306     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(99)80118-4     Document Type: Review
Times cited : (62)

References (127)
  • 1
    • 0030057089 scopus 로고    scopus 로고
    • HIV therapeutics
    • Richman DD. HIV therapeutics. Science. 272:1996;1886-1888.
    • (1996) Science , vol.272 , pp. 1886-1888
    • Richman, D.D.1
  • 2
    • 0031407309 scopus 로고    scopus 로고
    • Review: Present and future directions in the treatment of chronic hepatitis B infection
    • Nicoll A, Locarnini S. Review: present and future directions in the treatment of chronic hepatitis B infection. J Gastroenterol Hepatol. 12:1997;843-854.
    • (1997) J Gastroenterol Hepatol , vol.12 , pp. 843-854
    • Nicoll, A.1    Locarnini, S.2
  • 3
    • 0032125193 scopus 로고    scopus 로고
    • Review: Drug therapy for chronic hepatitis B: Antiviral efficacy and influence of hepatitis B virus polymerase mutations on the outcome of therapy
    • Zoulim F, Trepo C. Review: drug therapy for chronic hepatitis B: antiviral efficacy and influence of hepatitis B virus polymerase mutations on the outcome of therapy. J Hepatol. 29:1998;151-168.
    • (1998) J Hepatol , vol.29 , pp. 151-168
    • Zoulim, F.1    Trepo, C.2
  • 4
    • 84920307190 scopus 로고    scopus 로고
    • Significance of mutations in the hepatitis B vírus polymerase selected by nucleoside analogues and implications for controlling chronic disease
    • in press
    • Bartholomeusz, A, Schinazi, RF and Locarnini, SA, Significance of mutations in the hepatitis B vírus polymerase selected by nucleoside analogues and implications for controlling chronic disease, Viral Hep Rev, in press.
    • Viral Hep Rev
    • Bartholomeusz, A.1    Schinazi, R.F.2    Locarnini, S.A.3
  • 5
    • 0030603841 scopus 로고    scopus 로고
    • Changing the natural history of HIV disease
    • Feinberg MB. Changing the natural history of HIV disease. Lancet. 348:1996;239-246.
    • (1996) Lancet , vol.348 , pp. 239-246
    • Feinberg, M.B.1
  • 8
    • 0024273119 scopus 로고
    • The accuracy of reverse transcriptase from HIV-1
    • Roberts JD, Bebenek K, Kunkel TA. The accuracy of reverse transcriptase from HIV-1. Science. 242:1988;1171-1173.
    • (1988) Science , vol.242 , pp. 1171-1173
    • Roberts, J.D.1    Bebenek, K.2    Kunkel, T.A.3
  • 9
    • 15844378825 scopus 로고    scopus 로고
    • Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays
    • Kozal MJ, Shah N, Shen N, Yang R, Fucini R, Merigan TC, et al. Extensive polymorphisms observed in HIV-1 clade B protease gene using high-density oligonucleotide arrays. Nat Med. 2:1996;753-759.
    • (1996) Nat Med , vol.2 , pp. 753-759
    • Kozal, M.J.1    Shah, N.2    Shen, N.3    Yang, R.4    Fucini, R.5    Merigan, T.C.6
  • 10
    • 0028952146 scopus 로고
    • HIV population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy
    • Coffin JM. HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy. Science. 267:1995;483-489.
    • (1995) Science , vol.267 , pp. 483-489
    • Coffin, J.M.1
  • 11
    • 0028916425 scopus 로고
    • Hepatitis B virus immunopathogenesis
    • Chisari FV, Ferrari C. Hepatitis B virus immunopathogenesis. Ann Rev Immunol. 13:1995;29-60.
    • (1995) Ann Rev Immunol , vol.13 , pp. 29-60
    • Chisari, F.V.1    Ferrari, C.2
  • 13
    • 1842291578 scopus 로고    scopus 로고
    • The treatment of chronic viral hepatitis
    • Hoofnagle JH. The treatment of chronic viral hepatitis. Drug Ther. 336:1997;347-356.
    • (1997) Drug Ther , vol.336 , pp. 347-356
    • Hoofnagle, J.H.1
  • 15
    • 0031297181 scopus 로고    scopus 로고
    • Influence of T-helper cell subsets and cross regulation in hepatitis B virus infection
    • Milich DR. Influence of T-helper cell subsets and cross regulation in hepatitis B virus infection. J Viral Hepat. 4:(suppl 2):1997;48-59.
    • (1997) J Viral Hepat , vol.4 , Issue.SUPPL. 2 , pp. 48-59
    • Milich, D.R.1
  • 16
    • 0027979128 scopus 로고
    • Interleukin-2 and alpha/beta interferon down-regulate hepatitis B virus gene expression in vivo by tumour necrosis factor-dependent and independent pathways
    • Guidotti LG, Guilot S, Chisari FV. Interleukin-2 and alpha/beta interferon down-regulate hepatitis B virus gene expression in vivo by tumour necrosis factor-dependent and independent pathways. J Virol. 68:1994;1265-1270.
    • (1994) J Virol , vol.68 , pp. 1265-1270
    • Guidotti, L.G.1    Guilot, S.2    Chisari, F.V.3
  • 17
    • 14444273439 scopus 로고    scopus 로고
    • Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy
    • Finzi D, Hermankova M, Pierson T, Carruth LM, Buck C, Chaisson RE, et al. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science. 278:1997;1295-1300.
    • (1997) Science , vol.278 , pp. 1295-1300
    • Finzi, D.1    Hermankova, M.2    Pierson, T.3    Carruth, L.M.4    Buck, C.5    Chaisson, R.E.6
  • 18
    • 0030712305 scopus 로고    scopus 로고
    • Recovery of replication-competent HIV despite prolonged suppression of plasma viremia
    • Wong JK, Hezareh M, Gunthard HF, Havlir DV, Ignacio CC, Spina CA, et al. Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science. 278:1997;1291-1295.
    • (1997) Science , vol.278 , pp. 1291-1295
    • Wong, J.K.1    Hezareh, M.2    Gunthard, H.F.3    Havlir, D.V.4    Ignacio, C.C.5    Spina, C.A.6
  • 19
    • 0032492398 scopus 로고    scopus 로고
    • CD4-cell count in HIV-1-infected individuals remaining viraemic with highly active antiretroviral therapy (HAART)
    • Kaufman D, Pantaleo G, Sudre P, Telenti A. CD4-cell count in HIV-1-infected individuals remaining viraemic with highly active antiretroviral therapy (HAART). Lancet. 351:1998;723-724.
    • (1998) Lancet , vol.351 , pp. 723-724
    • Kaufman, D.1    Pantaleo, G.2    Sudre, P.3    Telenti, A.4
  • 20
    • 0028679793 scopus 로고
    • Treament of chronic hepatitis B
    • Lok ASF. Treament of chronic hepatitis B. J Viral Hepat. 1:1994;105-124.
    • (1994) J Viral Hepat , vol.1 , pp. 105-124
    • Lok Asf1
  • 21
    • 0032539436 scopus 로고    scopus 로고
    • Effect of interferon on hepatitis B
    • Carithers RL. Effect of interferon on hepatitis B. Lancet. 351:1998;157.
    • (1998) Lancet , vol.351 , pp. 157
    • Carithers, R.L.1
  • 22
    • 1842291578 scopus 로고    scopus 로고
    • The treatment of chronic viral hepatitis
    • Hoofnagle JH, DiBisceglie AM. The treatment of chronic viral hepatitis. N Engl J Med. 336:1997;347-356.
    • (1997) N Engl J Med , vol.336 , pp. 347-356
    • Hoofnagle, J.H.1    Dibisceglie, A.M.2
  • 23
    • 10144241676 scopus 로고    scopus 로고
    • 1, versus interferon alfa treatment in patients with hepatitis Be antigen antibody- And hepatitis B virus DNA-positive chronic hepatitis B
    • 1, versus interferon alfa treatment in patients with hepatitis Be antigen antibody- and hepatitis B virus DNA-positive chronic hepatitis B. Hepatology. 24:1996;774-777.
    • (1996) Hepatology , vol.24 , pp. 774-777
    • Andreone, P.1    Cursaro, C.2    Gramenzi, A.3    Zavaglia, C.4    Rezakovic, I.5    Altomare, E.6
  • 24
    • 0031596591 scopus 로고    scopus 로고
    • 1 in patients with chronic hepatitis B: A randomised controlled trial
    • 1 in patients with chronic hepatitis B: a randomised controlled trial. Hepatology. 27:1998;1383-1387.
    • (1998) Hepatology , vol.27 , pp. 1383-1387
    • Chien R-N1    Liaw Y-F2    Chen T-C3    Yeh C-T4    Sheen I-S5
  • 26
    • 0001242733 scopus 로고    scopus 로고
    • Efficacy of famciclovir in chronic hepatitis B: Results of a dose finding study
    • Trepo C, Jezek P, Atkinson G, Boon R. Efficacy of famciclovir in chronic hepatitis B: results of a dose finding study. [abstract] Hepatology. 24:1996;1881A.
    • (1996) Hepatology , vol.24
    • Trepo, C.1    Jezek, P.2    Atkinson, G.3    Boon, R.4
  • 27
    • 0000460551 scopus 로고    scopus 로고
    • A placebo-controlled phase I/II study of Adefovir Dipivoxil (bis-POM PMEA) in patients with chronic hepatitis B infection
    • Gilson R, Chopra K, Murray-Lyon I, Newell A, Nelson M, Tedder R, et al. A placebo-controlled phase I/II study of Adefovir Dipivoxil (bis-POM PMEA) in patients with chronic hepatitis B infection. [abstract] Hepatology. 24:1996;281A.
    • (1996) Hepatology , vol.24
    • Gilson, R.1    Chopra, K.2    Murray-Lyon, I.3    Newell, A.4    Nelson, M.5    Tedder, R.6
  • 28
    • 0009138689 scopus 로고    scopus 로고
    • A preliminary study of lobucavir for chronic hepatitis B
    • Bloomer J, Chan R, Sherman M, Ingraham P, DeHertogh D, the -008 study group. A preliminary study of lobucavir for chronic hepatitis B. [abstract] Hepatology. 26:(4 Pt2):1997;428A.
    • (1997) Hepatology , vol.26 , Issue.4 PART 2
    • Bloomer, J.1    Chan, R.2    Sherman, M.3    Ingraham, P.4    Dehertogh, D.5
  • 29
    • 0029037074 scopus 로고
    • The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes
    • Newbold JE, Xin H, Tencza M, Sherman G, Dean J, Bowden S, et al. The covalently closed duplex form of the hepadnavirus genome exists in situ as a heterogeneous population of viral minichromosomes. J Virol. 69:1995;3350-3357.
    • (1995) J Virol , vol.69 , pp. 3350-3357
    • Newbold, J.E.1    Xin, H.2    Tencza, M.3    Sherman, G.4    Dean, J.5    Bowden, S.6
  • 30
    • 0021934431 scopus 로고
    • Changes of hepatitis B virus DNA in liver and serum caused by recombinant leukocyte interferon treatment: Analysis of intrahepatic replicative hepatitis B virus DNA
    • Yokosuka O, Omata A, Imazeki F, Okuda K, Summers J. Changes of hepatitis B virus DNA in liver and serum caused by recombinant leukocyte interferon treatment: analysis of intrahepatic replicative hepatitis B virus DNA. Hepatology. 5:1985;728-734.
    • (1985) Hepatology , vol.5 , pp. 728-734
    • Yokosuka, O.1    Omata, A.2    Imazeki, F.3    Okuda, K.4    Summers, J.5
  • 31
    • 0029062327 scopus 로고
    • Reversion of duck hepatitis B virus DNA in vivo following cessation of treatment with the nucleoside analogue ganciclovir
    • Dean J, Bowden S, Locarnini S. Reversion of duck hepatitis B virus DNA in vivo following cessation of treatment with the nucleoside analogue ganciclovir. Antiviral Res. 27:1995;171-178.
    • (1995) Antiviral Res , vol.27 , pp. 171-178
    • Dean, J.1    Bowden, S.2    Locarnini, S.3
  • 32
    • 0030776176 scopus 로고    scopus 로고
    • Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular DNA of woodchuck hepatitis virus
    • Moraleda G, Saputelli J, Aldrich CE, Averett D, Condreay L, Mason WS. Lack of effect of antiviral therapy in nondividing hepatocyte cultures on the closed circular DNA of woodchuck hepatitis virus. J Virol. 71:1997;9392-9399.
    • (1997) J Virol , vol.71 , pp. 9392-9399
    • Moraleda, G.1    Saputelli, J.2    Aldrich, C.E.3    Averett, D.4    Condreay, L.5    Mason, W.S.6
  • 34
    • 0028024340 scopus 로고
    • The half-life of duck hepatitis B virus supercoiled DNA in congenitally infected primary hepatocyte cultures
    • Civitico G, Locarnini S. The half-life of duck hepatitis B virus supercoiled DNA in congenitally infected primary hepatocyte cultures. Virology. 203:1994;81-89.
    • (1994) Virology , vol.203 , pp. 81-89
    • Civitico, G.1    Locarnini, S.2
  • 35
    • 0028053046 scopus 로고
    • Characterization of the antiviral effects of 2′-carbodeoxy-guanosine in ducks chronically infected with duck hepatitis B virus
    • Mason WS, Cullen J, Saputelli J, Wu T-T, Liu C, London WT, et al. Characterization of the antiviral effects of 2′-carbodeoxy-guanosine in ducks chronically infected with duck hepatitis B virus. Hepatology. 19:1994;398-411.
    • (1994) Hepatology , vol.19 , pp. 398-411
    • Mason, W.S.1    Cullen, J.2    Saputelli, J.3    Wu T-T4    Liu, C.5    London, W.T.6
  • 36
    • 0029786431 scopus 로고    scopus 로고
    • Long-term ganciclovir chemotherapy for congenital duck hepatitis B virus infection in vivo: Effect on intrahepatic viral DNA, RNA, and protein expression
    • Luscombe C, Pedersen J, Uren E, Locarnini S. Long-term ganciclovir chemotherapy for congenital duck hepatitis B virus infection in vivo: effect on intrahepatic viral DNA, RNA, and protein expression. Hepatology. 24:1996;766-773.
    • (1996) Hepatology , vol.24 , pp. 766-773
    • Luscombe, C.1    Pedersen, J.2    Uren, E.3    Locarnini, S.4
  • 37
    • 0030061124 scopus 로고    scopus 로고
    • The guanine nucleoside analogue penciclovir is active against chronic duck hepatitis B virus infection in vivo
    • Lin E, Luscombe C, Wang Y, Shaw T, Locarnini S. The guanine nucleoside analogue penciclovir is active against chronic duck hepatitis B virus infection in vivo. Antimicrob Agents Chemother. 40:1996;413-418.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 413-418
    • Lin, E.1    Luscombe, C.2    Wang, Y.3    Shaw, T.4    Locarnini, S.5
  • 38
    • 0031879931 scopus 로고    scopus 로고
    • Long-term therapy with the guanine nucleoside analog penciclovir controls chronic duck hepatitis B virus infection in vivo
    • Lin E, Luscombe C, Colledge D, Wang YY, Locarnini SA. Long-term therapy with the guanine nucleoside analog penciclovir controls chronic duck hepatitis B virus infection in vivo. Antimicrob Agents Chemother. 42:1998;2132-2137.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 2132-2137
    • Lin, E.1    Luscombe, C.2    Colledge, D.3    Wang, Y.Y.4    Locarnini, S.A.5
  • 39
    • 0039144738 scopus 로고
    • Evaluation of drugs for antiviral activity against hepatitis B virus
    • Averett DR, Mason WS. Evaluation of drugs for antiviral activity against hepatitis B virus. Viral Hepatitis Reviews. 1:1995;129-142.
    • (1995) Viral Hepatitis Reviews , vol.1 , pp. 129-142
    • Averett, D.R.1    Mason, W.S.2
  • 40
    • 0000557449 scopus 로고    scopus 로고
    • Human immunodeficiency viruses and their replication
    • BN Fields, DM Knipe, & PM Howley. Philadelphia: Lippincott-Raven
    • Luciw P. Human immunodeficiency viruses and their replication. Fields BN, Knipe DM, Howley PM, . Fields Virology, 3rd ed. 1996;2703-2738 Lippincott-Raven, Philadelphia.
    • (1996) Fields Virology, 3rd Ed. , pp. 2703-2738
    • Luciw, P.1
  • 41
    • 0001435504 scopus 로고    scopus 로고
    • Hepadnaviridae: The viruses and their replication
    • BN Fields, DM Knipe, & PM Howley. Philadelphia: Lippincott-Raven
    • Ganem D. Hepadnaviridae: the viruses and their replication. Fields BN, Knipe DM, Howley PM, . Fields Virology, 3rd ed. 1996;2703-2738 Lippincott-Raven, Philadelphia.
    • (1996) Fields Virology, 3rd Ed. , pp. 2703-2738
    • Ganem, D.1
  • 42
    • 0029075130 scopus 로고
    • Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase
    • Mansby LM, Temin HM. Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase. J Virol. 69:1995;5087-5094.
    • (1995) J Virol , vol.69 , pp. 5087-5094
    • Mansby, L.M.1    Temin, H.M.2
  • 43
    • 0031612751 scopus 로고    scopus 로고
    • Hepatitis B virus surface antigen and polymerase gene variants: Potential virological and clinical significance
    • Locarnini S. Hepatitis B virus surface antigen and polymerase gene variants: potential virological and clinical significance. Hepatology. 27:1998;294-297.
    • (1998) Hepatology , vol.27 , pp. 294-297
    • Locarnini, S.1
  • 44
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamics in vivo: Virion clearance rate, infected cell life span, and viral generation time
    • Perelson AS, Neumann AU, Markowitz M, Leonard JM, Ho DD. HIV-1 dynamics in vivo: virion clearance rate, infected cell life span, and viral generation time. Science. 271:1996;1582-1585.
    • (1996) Science , vol.271 , pp. 1582-1585
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 48
    • 0029024089 scopus 로고
    • Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug resistant virus populations in persons treated with lamivudine (3TC)
    • Schuurman R, Nijhuis M, van Leeuwen R, Schipper P, de Jong D, Collis P, et al. Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug resistant virus populations in persons treated with lamivudine (3TC). J Infect Dis. 171:1995;1411-1419.
    • (1995) J Infect Dis , vol.171 , pp. 1411-1419
    • Schuurman, R.1    Nijhuis, M.2    Van Leeuwen, R.3    Schipper, P.4    De Jong, D.5    Collis, P.6
  • 49
    • 0028918674 scopus 로고
    • Development of HIV-1 resistance to (-) 2′-deoxy-3′-thiacytidine in patients with AIDS or advanced AIDS-related complex
    • Wainberg MA, Salomon H, Gu Z, Montaner JS, Cooley TP, MacCaffey R, et al. Development of HIV-1 resistance to (-) 2′-deoxy-3′-thiacytidine in patients with AIDS or advanced AIDS-related complex. AIDS. 9:1995;351-357.
    • (1995) AIDS , vol.9 , pp. 351-357
    • Wainberg Ma1    Salomon, H.2    Gu, Z.3    Montaner, J.S.4    Cooley, T.P.5    MacCaffey, R.6
  • 50
    • 0028988479 scopus 로고
    • Pol gene quasispecies of human immunodeficiency virus mutations associated with drug resistance in virus from patients undergoing no drug therapy
    • Najera I, Holguin A, Quinones-Mateu ME, Monoz-Fernandez MA, Najera R, Lopez-Galindez C, et al. Pol gene quasispecies of human immunodeficiency virus mutations associated with drug resistance in virus from patients undergoing no drug therapy. J Virol. 69:1995;23-31.
    • (1995) J Virol , vol.69 , pp. 23-31
    • Najera, I.1    Holguin, A.2    Quinones-Mateu, M.E.3    Monoz-Fernandez Ma4    Najera, R.5    Lopez-Galindez, C.6
  • 51
    • 0031938029 scopus 로고    scopus 로고
    • Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective
    • Melegari M, Scaglioni PP, Wands JR. Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective. Hepatology. 27:1998;628-633.
    • (1998) Hepatology , vol.27 , pp. 628-633
    • Melegari, M.1    Scaglioni, P.P.2    Wands Jr3
  • 54
    • 0030317890 scopus 로고    scopus 로고
    • Viral dynamics of HIV: Implications for drug development and therapeutie strategies
    • Havlir DV, Richman DD. Viral dynamics of HIV: implications for drug development and therapeutie strategies. Ann Intern Med. 124:1996;984-994.
    • (1996) Ann Intern Med , vol.124 , pp. 984-994
    • Havlir, D.V.1    Richman, D.D.2
  • 55
    • 0022996630 scopus 로고
    • Phosphorylation of 3′-azido-3′-deoxythymidine and selective interaction of the 5′-triphosphate with human immunodeficiency virus reverse transcriptase
    • Furman P, Fyfe JA, St Clair M, Weinhold K, Ridcout JL, Freeman GA, et al. Phosphorylation of 3′-azido-3′-deoxythymidine and selective interaction of the 5′-triphosphate with human immunodeficiency virus reverse transcriptase. Proc Natl Acad Sci USA. 83:1986;8333-8337.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 8333-8337
    • Furman, P.1    Fyfe, J.A.2    St Clair, M.3    Weinhold, K.4    Ridcout, J.L.5    Freeman, G.A.6
  • 56
    • 0344624573 scopus 로고
    • Structure of HIV-1 reverse transcriptase complexed with a double-stranded DNA template-primer: Inplications for catalysis by and evolution of DNA polymerases
    • Arnold E, Jacobo-Molina A, Nanni RG, Williams RL, Lu X, Ding S, et al. Structure of HIV-1 reverse transcriptase complexed with a double-stranded DNA template-primer: inplications for catalysis by and evolution of DNA polymerases. Int Antiviral News. 1:1992;3-4.
    • (1992) Int Antiviral News , vol.1 , pp. 3-4
    • Arnold, E.1    Jacobo-Molina, A.2    Nanni, R.G.3    Williams, R.L.4    Lu, X.5    Ding, S.6
  • 57
    • 0031015475 scopus 로고    scopus 로고
    • Impaired fitness of human immunodeficiency virus type 1 variants with high-level resistance to protease inhibitors
    • Croteau G, Doyon L, Thibeault D, McKercher G, Pilote L, Lamarre D, et al. Impaired fitness of human immunodeficiency virus type 1 variants with high-level resistance to protease inhibitors. J Virol. 71:1997;1089-1096.
    • (1997) J Virol , vol.71 , pp. 1089-1096
    • Croteau, G.1    Doyon, L.2    Thibeault, D.3    McKercher, G.4    Pilote, L.5    Lamarre, D.6
  • 58
    • 10344263394 scopus 로고    scopus 로고
    • Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor
    • Condra J, Holder DJ, Schleif WA, Blahy OM, Danovich RM, Gabryelski W, et al. Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. J Virol. 70:1996;8270-8276.
    • (1996) J Virol , vol.70 , pp. 8270-8276
    • Condra, J.1    Holder, D.J.2    Schleif, W.A.3    Blahy, O.M.4    Danovich, R.M.5    Gabryelski, W.6
  • 59
    • 0030769354 scopus 로고    scopus 로고
    • Drug resistance during indinavir therapy is caused by mutations in the protease gene and its gag substrate cleavage sites
    • Zhang YM, Imamichi H, Imamichi T, Lane HC, Falloar J, Casudevachari MB, et al. Drug resistance during indinavir therapy is caused by mutations in the protease gene and its gag substrate cleavage sites. J Virol. 71:1997;6662-6670.
    • (1997) J Virol , vol.71 , pp. 6662-6670
    • Zhang, Y.M.1    Imamichi, H.2    Imamichi, T.3    Lane, H.C.4    Falloar, J.5    Casudevachari, M.B.6
  • 60
    • 0023268502 scopus 로고
    • The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex
    • Fischl MA, Richman DD, Grieco MH, Gottleib MS, Volberding PA, Laskin OL, et al. The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. N Engl J Med. 317:1987;185-191.
    • (1987) N Engl J Med , vol.317 , pp. 185-191
    • Fischl Ma1    Richman, D.D.2    Grieco, M.H.3    Gottleib, M.S.4    Volberding, P.A.5    Laskin, O.L.6
  • 61
    • 0029798237 scopus 로고    scopus 로고
    • Nevirapine-resistant human immunodeficiency virus: Kinetics of replication and estimated prevalence in untreated patients
    • Havlir DV, Eastman S, Gamst A, Richman DD. Nevirapine-resistant human immunodeficiency virus: kinetics of replication and estimated prevalence in untreated patients. J Virol. 70:1996;7894-7899.
    • (1996) J Virol , vol.70 , pp. 7894-7899
    • Havlir, D.V.1    Eastman, S.2    Gamst, A.3    Richman, D.D.4
  • 62
    • 0024508058 scopus 로고
    • HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy
    • Larder BA, Darby G, Richman DD. HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy. Science. 243:1989;1731-1734.
    • (1989) Science , vol.243 , pp. 1731-1734
    • Larder, B.A.1    Darby, G.2    Richman, D.D.3
  • 63
    • 0027957791 scopus 로고
    • Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during drug therapy
    • Richman DD, Havlir D, Corbeil J, Looney D, Ignacio C, Spector SA, et al. Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during drug therapy. J Virol. 68:1994;1660-1666.
    • (1994) J Virol , vol.68 , pp. 1660-1666
    • Richman, D.D.1    Havlir, D.2    Corbeil, J.3    Looney, D.4    Ignacio, C.5    Spector, S.A.6
  • 64
    • 0026705125 scopus 로고
    • Incidence of zidovudine-resistant human immunodeficiency virus isolated from patients before, during, and after therapy
    • Land S, McGavin C, Lucas R, Birch C. Incidence of zidovudine-resistant human immunodeficiency virus isolated from patients before, during, and after therapy. J Infect Dis. 166:1992;1139-1142.
    • (1992) J Infect Dis , vol.166 , pp. 1139-1142
    • Land, S.1    McGavin, C.2    Lucas, R.3    Birch, C.4
  • 65
    • 0028785708 scopus 로고
    • L-743,726 (DMP-266): A novel, highly potent nonnucleoside inhibitor of the human immunodeficiency virus type 1 reverse transcriptase
    • Young SD, Britcher SF, Tran LO, Payne LS, Lumma C, Lyle TA, et al. L-743,726 (DMP-266): a novel, highly potent nonnucleoside inhibitor of the human immunodeficiency virus type 1 reverse transcriptase. Antimicrob Agents Chemother. 39:1995;2602-2605.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 2602-2605
    • Young, S.D.1    Britcher, S.F.2    Tran, L.O.3    Payne, L.S.4    Lumma, C.5    Lyle, T.A.6
  • 66
    • 0029838243 scopus 로고    scopus 로고
    • Mutations in retroviral genes associated with drug resistance
    • Schinazi RF, Larder BA, Mellors JW. Mutations in retroviral genes associated with drug resistance. Int Antiviral News. 4:1996;95-107.
    • (1996) Int Antiviral News , vol.4 , pp. 95-107
    • Schinazi, R.F.1    Larder, B.A.2    Mellors, J.W.3
  • 69
    • 0026469165 scopus 로고
    • The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1- (2-(hydroxymethyl)-1.3-oxathiolan-5-yl)cytosine
    • Furman PA, Davis M, Liotta DC, Paff M, Frick JW, Nelson DJ, et al. The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1- (2-(hydroxymethyl)-1.3-oxathiolan-5-yl)cytosine. Antimicrob Agents Chemother. 36:1992;2686-2692.
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 2686-2692
    • Furman, P.A.1    Davis, M.2    Liotta, D.C.3    Paff, M.4    Frick, J.W.5    Nelson, D.J.6
  • 70
    • 0002228845 scopus 로고    scopus 로고
    • The mechanism of action of antiviral agents in chronic hepatitis B
    • Luscombe CA, Locarnini SA. The mechanism of action of antiviral agents in chronic hepatitis B. Viral Hepatitis Reviews. 2:1996;1-35.
    • (1996) Viral Hepatitis Reviews , vol.2 , pp. 1-35
    • Luscombe, C.A.1    Locarnini, S.A.2
  • 71
    • 0029047348 scopus 로고
    • Hepatic purine and pyrimidine metabolism: Implications for the design of antiviral agents
    • Shaw T, Locarnini S. Hepatic purine and pyrimidine metabolism: implications for the design of antiviral agents. Liver. 15:1995;169-184.
    • (1995) Liver , vol.15 , pp. 169-184
    • Shaw, T.1    Locarnini, S.2
  • 72
    • 2642651109 scopus 로고    scopus 로고
    • Acyclic nucleoside phosphonates in the chemotherapy of DNA virus and retrovirus infections
    • DeClercq E. Acyclic nucleoside phosphonates in the chemotherapy of DNA virus and retrovirus infections. Invervirology. 40:1997;295-303.
    • (1997) Invervirology , vol.40 , pp. 295-303
    • Declercq, E.1
  • 74
    • 0030997139 scopus 로고    scopus 로고
    • Interleukin 12 inhibits hepatitis B virus replication in transgenic mice
    • Cavanagh VJ, Guidotti LG, Chisari FV. Interleukin 12 inhibits hepatitis B virus replication in transgenic mice. J Virol. 71:1997;3236-3243.
    • (1997) J Virol , vol.71 , pp. 3236-3243
    • Cavanagh, V.J.1    Guidotti, L.G.2    Chisari, F.V.3
  • 76
    • 0023639047 scopus 로고
    • Modulation of human natural killer cytotoxic activity, lymphokine production and interleukin 2 receptor expression by thymic hormones
    • Scrrate SA, Schulof RS, Leondaridis L, Goldstcin AL, Sztein MB. Modulation of human natural killer cytotoxic activity, lymphokine production and interleukin 2 receptor expression by thymic hormones. J Immunol. 139:1987;2338-2343.
    • (1987) J Immunol , vol.139 , pp. 2338-2343
    • Scrrate, S.A.1    Schulof, R.S.2    Leondaridis, L.3    Goldstcin, A.L.4    Sztein, M.B.5
  • 77
    • 0026533139 scopus 로고
    • Frequent and rapid emergence of mutated pre-C sequences in HBV from e-antigen positive carriers who seroconvert to anti-HBe during interferon treatment
    • Gunther S, Meisel H, Reip A, Miska S, Kruger DH, Will H. Frequent and rapid emergence of mutated pre-C sequences in HBV from e-antigen positive carriers who seroconvert to anti-HBe during interferon treatment. Virology. 187:1992;271-279.
    • (1992) Virology , vol.187 , pp. 271-279
    • Gunther, S.1    Meisel, H.2    Reip, A.3    Miska, S.4    Kruger, D.H.5    Will, H.6
  • 78
    • 0029817898 scopus 로고    scopus 로고
    • Mutation in HBV-RNA-dependent DNA polymerase confers resistance to lamivudine in vivo
    • Tipples GA, Ma MM, Fischer KP, Bain VG, Kneteman NM, Tyrrell DLJ. Mutation in HBV-RNA-dependent DNA polymerase confers resistance to lamivudine in vivo. Hepatology. 24:1996;714-717.
    • (1996) Hepatology , vol.24 , pp. 714-717
    • Tipples, G.A.1    Ma, M.M.2    Fischer Kp3    Bain, V.G.4    Kneteman, N.M.5    Tyrrell Dlj6
  • 79
    • 0030905343 scopus 로고    scopus 로고
    • Hepatitis B virus polymerase mutations during antiviral therapy in a patient following liver transplantation
    • Aye TT, Bartholomeusz A, Shaw T, Bowden S, Breschkin A, McMillan J, et al. Hepatitis B virus polymerase mutations during antiviral therapy in a patient following liver transplantation. J Hepatol. 26:1997;1148-1153.
    • (1997) J Hepatol , vol.26 , pp. 1148-1153
    • Aye, T.T.1    Bartholomeusz, A.2    Shaw, T.3    Bowden, S.4    Breschkin, A.5    McMillan, J.6
  • 80
    • 0031037065 scopus 로고    scopus 로고
    • Hepatitis B virus resistance to lamivudine given for recurrent infection after orthotopic liver transplantation
    • Bartholomew MM, Jansen RW, Jeffers LJ, Reddy KR, Johnson CC, Bunzendahl H, et al. Hepatitis B virus resistance to lamivudine given for recurrent infection after orthotopic liver transplantation. Lancet. 349:1997;20-22.
    • (1997) Lancet , vol.349 , pp. 20-22
    • Bartholomew, M.M.1    Jansen, R.W.2    Jeffers, L.J.3    Reddy, K.R.4    Johnson, C.C.5    Bunzendahl, H.6
  • 81
    • 0027285372 scopus 로고
    • Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of the reverse transcriptase
    • Tisdale M, Kemp SD, Parry NR, Larder BA. Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of the reverse transcriptase. Proc Natl Acad Sci USA. 90:1993;5653-5656.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5653-5656
    • Tisdale, M.1    Kemp, S.D.2    Parry, N.R.3    Larder, B.A.4
  • 83
    • 0029151329 scopus 로고
    • Penciclovir resistance mutations in the herpes simplex virus DNA polymerase gene
    • Chiou HC, Kumura K, Hu A, Kerns KM, Coen DM. Penciclovir resistance mutations in the herpes simplex virus DNA polymerase gene. Antiviral Chem Chemother. 6:1995;281-288.
    • (1995) Antiviral Chem Chemother , vol.6 , pp. 281-288
    • Chiou, H.C.1    Kumura, K.2    Hu, A.3    Kerns, K.M.4    Coen, D.M.5
  • 84
    • 0029815110 scopus 로고    scopus 로고
    • Selection of mutations in the hepatitis B virus polymerase during therapy of transplant recipients with lamivudine
    • Ling R, Mutimer D, Ahmed M, Boxall E, Elias E, Dusheiko M, et al. Selection of mutations in the hepatitis B virus polymerase during therapy of transplant recipients with lamivudine. Hepatology. 24:1996;711-713.
    • (1996) Hepatology , vol.24 , pp. 711-713
    • Ling, R.1    Mutimer, D.2    Ahmed, M.3    Boxall, E.4    Elias, E.5    Dusheiko, M.6
  • 85
    • 0001401439 scopus 로고    scopus 로고
    • Emergence and characterization of lamivudine resistant hepatitis B virus variant
    • Naoumov NV, Chokski S, Smith HM, Williams R. Emergence and characterization of lamivudine resistant hepatitis B virus variant. [abstract] Hepatology. 24:1996;282A.
    • (1996) Hepatology , vol.24
    • Naoumov, N.V.1    Chokski, S.2    Smith, H.M.3    Williams, R.4
  • 86
    • 0344212334 scopus 로고    scopus 로고
    • The occurrence of sequential viral mutations in a liver transplant recipient re-infected with hepatitis B: Primary famciclovir resistance followed by a lethal hepatitis acquired during lamivudine resistance
    • de Man RA, Bartholomeusz A, Locarnini S, Niesters HGM, Zondervan PE. The occurrence of sequential viral mutations in a liver transplant recipient re-infected with hepatitis B: primary famciclovir resistance followed by a lethal hepatitis acquired during lamivudine resistance. J Hepatol. 26:(Suppl 1):1997;79.
    • (1997) J Hepatol , vol.26 , Issue.SUPPL. 1 , pp. 79
    • De Man, R.A.1    Bartholomeusz, A.2    Locarnini, S.3    Niesters Hgm4    Zondervan, P.E.5
  • 87
    • 0003069317 scopus 로고    scopus 로고
    • A 12 month course of lamivudine (100 mg od) therapy improves liver histology: Results from a placebo controlled multicenter study in Asia
    • Lai CL, Liaw YF, Leung NWY, Chang TT, Guan R, Tai DI, et al. A 12 month course of lamivudine (100 mg od) therapy improves liver histology: results from a placebo controlled multicenter study in Asia. J Hepatol. 26:(Suppl 1):1997;79.
    • (1997) J Hepatol , vol.26 , Issue.SUPPL. 1 , pp. 79
    • Lai, C.L.1    Liaw, Y.F.2    Leung Nwy3    Chang, T.T.4    Guan, R.5    Tai Di6
  • 88
    • 0030875066 scopus 로고    scopus 로고
    • Lamivudine resistance in immunocompetent chronic hepatitis B: Incidence and patterns
    • Honkoop P, Niesters HGM, deMan RAM, Osterhaus ADME, Schalm SW. Lamivudine resistance in immunocompetent chronic hepatitis B: incidence and patterns. J Hepatol. 26:1997;1393-1395.
    • (1997) J Hepatol , vol.26 , pp. 1393-1395
    • Honkoop, P.1    Niesters Hgm2    Deman Ram3    Osterhaus Adme4    Schalm, S.W.5
  • 89
    • 0008384291 scopus 로고    scopus 로고
    • Response and mutations in patients sequentially treated with lamivudine and famciclovir for recurrent hepatitis B after liver transplantation
    • Tillman HL, Trautwein C, Bock T, Glowenka M, Kruger M, Boker K, et al. Response and mutations in patients sequentially treated with lamivudine and famciclovir for recurrent hepatitis B after liver transplantation. [abstract] Hepatology. 26:(4Pt2):1997;A1202.
    • (1997) Hepatology , vol.26 , Issue.4 PART 2
    • Tillman, H.L.1    Trautwein, C.2    Bock, T.3    Glowenka, M.4    Kruger, M.5    Boker, K.6
  • 90
    • 2642679257 scopus 로고    scopus 로고
    • Clinical experience with famciclovir against hepatitis B virus and development of resistance
    • Bartholomeusz A, Groenen LC, Locarnini SA. Clinical experience with famciclovir against hepatitis B virus and development of resistance. Intervirology. 40:1997;337-342.
    • (1997) Intervirology , vol.40 , pp. 337-342
    • Bartholomeusz, A.1    Groenen, L.C.2    Locarnini, S.A.3
  • 91
    • 0000987382 scopus 로고    scopus 로고
    • The emergence of famciclovir resistance mutations in the hepatitis B virus polymerase during therapy following liver transplantation
    • Locarnini SA, Aye TT, Shaw T, deMan R, Angus PW, McCaughan GW. The emergence of famciclovir resistance mutations in the hepatitis B virus polymerase during therapy following liver transplantation. [abstract] Hepatology. 26:(4 pt2):1997;A958.
    • (1997) Hepatology , vol.26 , Issue.4 PART 2
    • Locarnini, S.A.1    Aye, T.T.2    Shaw, T.3    Deman, R.4    Angus, P.W.5    McCaughan, G.W.6
  • 92
    • 0000076031 scopus 로고    scopus 로고
    • Lack of cross-resistance to PMEA for human hepatitis B DNA polymerases which express Lamivudine resistance codons
    • Xiong X, Flores C, Gibbs C, Toole J. Lack of cross-resistance to PMEA for human hepatitis B DNA polymerases which express Lamivudine resistance codons. [abstract] Hepatology. 26:(4Pt2):1997;A1211.
    • (1997) Hepatology , vol.26 , Issue.4 PART 2
    • Xiong, X.1    Flores, C.2    Gibbs, C.3    Toole, J.4
  • 93
    • 0031780935 scopus 로고    scopus 로고
    • Identification and characterization of mutations in hepatitis B virus resistant to lamivudine
    • Allen MI, Deslauriers M, Andrews CW, Tipples GA, Walters K, Tyrrell DLJ, et al. Identification and characterization of mutations in hepatitis B virus resistant to lamivudine. Hepatology. 27:1998;1670-1677.
    • (1998) Hepatology , vol.27 , pp. 1670-1677
    • Allen, M.I.1    Deslauriers, M.2    Andrews, C.W.3    Tipples, G.A.4    Walters, K.5    Tyrrell Dlj6
  • 96
    • 0028948198 scopus 로고
    • Evaluation of safety and efficacy of 3TC (lamivudine) in patients with asymptomatic or mildly symptomatic human immunodeficiency virus infection: A phase I/II study
    • van Leeuwen R, Katlama C, Kitchen V, Boucher CA, Tubiana R, McBride M, et al. Evaluation of safety and efficacy of 3TC (lamivudine) in patients with asymptomatic or mildly symptomatic human immunodeficiency virus infection: a phase I/II study. J Infect Dis. 171:1995;1166-1171.
    • (1995) J Infect Dis , vol.171 , pp. 1166-1171
    • Van Leeuwen, R.1    Katlama, C.2    Kitchen, V.3    Boucher, C.A.4    Tubiana, R.5    McBride, M.6
  • 97
    • 0028841148 scopus 로고
    • Study on didanosine concentrations in cerebrospinal fluid. Implications for the treatment and prevention of AIDS demential complex
    • Burger DM, Kraayeveld CL, Meenhorst PL, Mulder JW, Hoetelmans RM, Koks CH, et al. Study on didanosine concentrations in cerebrospinal fluid. Implications for the treatment and prevention of AIDS demential complex. Pharm World Sci. 17:1995;218-221.
    • (1995) Pharm World Sci , vol.17 , pp. 218-221
    • Burger, D.M.1    Kraayeveld, C.L.2    Meenhorst, P.L.3    Mulder, J.W.4    Hoetelmans, R.M.5    Koks Ch6
  • 98
    • 0031946993 scopus 로고    scopus 로고
    • In vitro blood-brain permeability of nevirapine compared to other antiretroviral agents
    • Glynn SL, Yazdanian M. In vitro blood-brain permeability of nevirapine compared to other antiretroviral agents. J Pharm Sci. 87:1998;306-310.
    • (1998) J Pharm Sci , vol.87 , pp. 306-310
    • Glynn, S.L.1    Yazdanian, M.2
  • 99
    • 0031475151 scopus 로고    scopus 로고
    • The entry of antiviral and antiretroviral drugs into the central nervous system
    • Grootis DR, Levy RM. The entry of antiviral and antiretroviral drugs into the central nervous system. J Neurovirol. 3:1997;387-400.
    • (1997) J Neurovirol , vol.3 , pp. 387-400
    • Grootis, D.R.1    Levy, R.M.2
  • 100
    • 0025003572 scopus 로고
    • Significance of extrahepatic replication of hepatitis B virus
    • Omata M. Significance of extrahepatic replication of hepatitis B virus. Hepatology. 12:1991;364-366.
    • (1991) Hepatology , vol.12 , pp. 364-366
    • Omata, M.1
  • 101
    • 0028111969 scopus 로고
    • Alterations in intrahepatic expression of duck hepatitis B viral markers with ganciclovir chemotherapy
    • Luscombe C, Pedersen J, Bowden S, Locarnini S. Alterations in intrahepatic expression of duck hepatitis B viral markers with ganciclovir chemotherapy. Liver. 14:1994;182-192.
    • (1994) Liver , vol.14 , pp. 182-192
    • Luscombe, C.1    Pedersen, J.2    Bowden, S.3    Locarnini, S.4
  • 102
    • 0001765014 scopus 로고
    • Hepatitis Be antigen negative chronic hepatitis B: From clinical recognition to pathogenesis and treatment
    • Hadziyannis S. Hepatitis Be antigen negative chronic hepatitis B: from clinical recognition to pathogenesis and treatment. Viral Hep Rev. 1:1995;7-36.
    • (1995) Viral Hep Rev , vol.1 , pp. 7-36
    • Hadziyannis, S.1
  • 103
    • 0011102859 scopus 로고    scopus 로고
    • Pathogenic effects of antiviral therapy in chronic hepatitis B virus infection
    • RF Schinazi, JP Sommadossi, & HC Thomas. London: International Medical Press
    • Lee J-Y, Colledge D, Locarnini S. Pathogenic effects of antiviral therapy in chronic hepatitis B virus infection. Schinazi RF, Sommadossi JP, Thomas HC, . Therapies for Viral Hepatitis. 1998;9-26 International Medical Press, London.
    • (1998) Therapies for Viral Hepatitis , pp. 9-26
    • Lee J-Y1    Colledge, D.2    Locarnini, S.3
  • 104
    • 0031728650 scopus 로고    scopus 로고
    • Inhibition of duck hepatitis B virus replication by 9-(2-phosphonyl-methoxyethyl)adenine (PMEA), an acyclic phosphonate nucleoside analogue
    • in press
    • Nicoll A, Colledge DL, Toole JJ, Angus PW, Smallwood R, Locarnini S. Inhibition of duck hepatitis B virus replication by 9-(2-phosphonyl-methoxyethyl)adenine (PMEA), an acyclic phosphonate nucleoside analogue. Antimicrob Agents Chemother. 1998;. (in press).
    • (1998) Antimicrob Agents Chemother
    • Nicoll, A.1    Colledge, D.L.2    Toole, J.J.3    Angus, P.W.4    Smallwood, R.5    Locarnini, S.6
  • 106
    • 0029777564 scopus 로고    scopus 로고
    • Therapy for human immunodeficiency virus infection: What have we learned?
    • Corey L, Holmes KK. Therapy for human immunodeficiency virus infection: what have we learned? N Engl J Med. 335:1996;1142-1144.
    • (1996) N Engl J Med , vol.335 , pp. 1142-1144
    • Corey, L.1    Holmes, K.K.2
  • 107
    • 0005150171 scopus 로고    scopus 로고
    • The relation of virologic and immunologic markers to clinical outcomes after nucleside therapy in HIV-infected adults with 200 to 500 CD4 cells per cubic millimeter
    • Katzenstein DA, Hammer SM, Hughes MD. The relation of virologic and immunologic markers to clinical outcomes after nucleside therapy in HIV-infected adults with 200 to 500 CD4 cells per cubic millimeter. N Engl J Med. 335:1996;1091-1098.
    • (1996) N Engl J Med , vol.335 , pp. 1091-1098
    • Katzenstein, D.A.1    Hammer, S.M.2    Hughes, M.D.3
  • 108
    • 0029940354 scopus 로고    scopus 로고
    • Viral Counts count in HIV infection
    • Ho DD. Viral Counts count in HIV infection. Science. 272:1996;1124-1125.
    • (1996) Science , vol.272 , pp. 1124-1125
    • Ho, D.D.1
  • 109
    • 0031046755 scopus 로고    scopus 로고
    • Line Probe Assay for rapid detection of drugselected mutations in the human immunodeficiency virus type 1 reverse transcriptase gene
    • Stuyver L, Wyseur A, Rombout A, Louwagie J, Scarcez T, Verhofstede C, et al. Line Probe Assay for rapid detection of drugselected mutations in the human immunodeficiency virus type 1 reverse transcriptase gene. Antimicrob Agents Chemother. 41:1997;284-291.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 284-291
    • Stuyver, L.1    Wyseur, A.2    Rombout, A.3    Louwagie, J.4    Scarcez, T.5    Verhofstede, C.6
  • 110
    • 0031006111 scopus 로고    scopus 로고
    • Changes in plasma HIV RNA levels and CD4+lymphocyte counts predict both response to antiretroviral therapy and therapeutic failure
    • O'Brien WA, Hartigan PM, Daar ES, Simberkoff MS, Hamilton JD. Changes in plasma HIV RNA levels and CD4+lymphocyte counts predict both response to antiretroviral therapy and therapeutic failure. Ann Intern Med. 126:1997;939-945.
    • (1997) Ann Intern Med , vol.126 , pp. 939-945
    • O'Brien, W.A.1    Hartigan, P.M.2    Daar, E.S.3    Simberkoff, M.S.4    Hamilton, J.D.5
  • 111
    • 84920305210 scopus 로고    scopus 로고
    • Multi-measurement method (MMM)-based assessment of commercial HBV DNA assays and the Roche Amplicor HBV Monitor™ test
    • Krajden M, Minor J, Zhao J, Comanor L. Multi-measurement method (MMM)-based assessment of commercial HBV DNA assays and the Roche Amplicor HBV Monitor™ test. [abstract] Hepatology. 26:(4Pt2):1997;317A.
    • (1997) Hepatology , vol.26 , Issue.4 PART 2
    • Krajden, M.1    Minor, J.2    Zhao, J.3    Comanor, L.4
  • 112
    • 0031829786 scopus 로고    scopus 로고
    • Statistical models for predicting a beneficial response to interferon alpha in patients with chronic hepatitis B
    • Lau DT, Comanor L, Minor JM, Everhart JE, Wuestehube LJ, Hoofnagle JH. Statistical models for predicting a beneficial response to interferon alpha in patients with chronic hepatitis B. J Viral Hep. 5:1998;105-114.
    • (1998) J Viral Hep , vol.5 , pp. 105-114
    • Lau, D.T.1    Comanor, L.2    Minor, J.M.3    Everhart, J.E.4    Wuestehube, L.J.5    Hoofnagle, J.H.6
  • 113
    • 0344192816 scopus 로고    scopus 로고
    • Development of quantitative PCR to detect hepatitis B virus covalently closed circular DNA molecules in liver biopsy specimens
    • in press
    • Dean J, Bowden DS, Angus P, Locarnini S. Development of quantitative PCR to detect hepatitis B virus covalently closed circular DNA molecules in liver biopsy specimens. Hepatology. 28:(4Pt2):1998;. in press.
    • (1998) Hepatology , vol.28 , Issue.4 PART 2
    • Dean, J.1    Bowden, D.S.2    Angus, P.3    Locarnini, S.4
  • 114
    • 0028990381 scopus 로고
    • Mitochondrial toxicity of antiviral drugs
    • Lewis W, Dalakas MC. Mitochondrial toxicity of antiviral drugs. Nat Med. 1:1995;417-422.
    • (1995) Nat Med , vol.1 , pp. 417-422
    • Lewis, W.1    Dalakas, M.C.2
  • 115
    • 0028817865 scopus 로고
    • Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B
    • McKenzie R, Fried MW, Sallie R, Conjeevaram H, DiBisceglie AM, Park Y, et al. Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B. N Engl J Med. 333:1995;1099-1105.
    • (1995) N Engl J Med , vol.333 , pp. 1099-1105
    • McKenzie, R.1    Fried, M.W.2    Sallie, R.3    Conjeevaram, H.4    Dibisceglie, A.M.5    Park, Y.6
  • 116
    • 0030986887 scopus 로고    scopus 로고
    • Effect of lamikvudine on morphology and function of mitochondria in patients with chronic hepatitis B
    • Honkoop P, deMan RA, Scholte HR, Zondervan PE, Van Den Berg JWO, Rademekers LHPM, et al. Effect of lamikvudine on morphology and function of mitochondria in patients with chronic hepatitis B. Hepatology. 26:1997;211-215.
    • (1997) Hepatology , vol.26 , pp. 211-215
    • Honkoop, P.1    Deman, R.A.2    Scholte, H.R.3    Zondervan, P.E.4    Van Den Berg Jwo5    Rademekers Lhpm6
  • 117
    • 0032499913 scopus 로고    scopus 로고
    • A one-year trial of lamivudine for chronic hepatitis B
    • Lai C-L, Chien R-N, Leung NWY, Chang T-T, Guan R, Tai D-I, et al. A one-year trial of lamivudine for chronic hepatitis B. N Engl J Med. 339:1998;61-68.
    • (1998) N Engl J Med , vol.339 , pp. 61-68
    • Lai C-L1    Chien R-N2    Leung Nwy3    Chang T-T4    Guan, R.5    Tai D-I6
  • 118
    • 0029095483 scopus 로고
    • Time to hit HIV, early and hard
    • Ho DD. Time to hit HIV, early and hard. N Engl J Med. 333:1995;450-451.
    • (1995) N Engl J Med , vol.333 , pp. 450-451
    • Ho, D.D.1
  • 120
    • 0021999466 scopus 로고
    • Acute AIDS retrovirus infection: Definition of a clinical illness associated with seroconversion
    • Cooper DA, Gold J, Maclean P, Donovan B, Finlayson R, Barnes TG, et al. Acute AIDS retrovirus infection: definition of a clinical illness associated with seroconversion. Lancet. i:1985;537-540.
    • (1985) Lancet , vol.1 , pp. 537-540
    • Cooper, D.A.1    Gold, J.2    MacLean, P.3    Donovan, B.4    Finlayson, R.5    Barnes, T.G.6
  • 121
    • 0025980126 scopus 로고
    • Primary HIV infection: Host responses and intervention strategies
    • Tindall B, Cooper DA. Primary HIV infection: host responses and intervention strategies. AIDS. 5:1991;1-14.
    • (1991) AIDS , vol.5 , pp. 1-14
    • Tindall, B.1    Cooper, D.A.2
  • 122
    • 0344624567 scopus 로고    scopus 로고
    • Analysis of hepatitis B virus DNA isolated from liver and serum pre and post liver transplantion during the emergence of HBIG escape mutants
    • in press
    • Locarnini SA, Ayres A, Dean J, Angus P, Bartholomeusz A. Analysis of hepatitis B virus DNA isolated from liver and serum pre and post liver transplantion during the emergence of HBIG escape mutants. Hepatology. 28:(4, Pt2):1998;. in press.
    • (1998) Hepatology , vol.28 , Issue.4 PART 2
    • Locarnini, S.A.1    Ayres, A.2    Dean, J.3    Angus, P.4    Bartholomeusz, A.5
  • 123
    • 0030926706 scopus 로고    scopus 로고
    • Synergistic inhibition of hepadnaviral replication by lamivudine in combination with penciclovir in vitro
    • Colledge D, Locarnini S, Shaw T. Synergistic inhibition of hepadnaviral replication by lamivudine in combination with penciclovir in vitro. Hepatology. 26:197;216-225.
    • Hepatology , vol.197 , Issue.26 , pp. 216-225
    • Colledge, D.1    Locarnini, S.2    Shaw, T.3
  • 124
    • 0030949106 scopus 로고    scopus 로고
    • Combination therapy for chronic hepatitis B
    • Fontana RJ, Lok ASF. Combination therapy for chronic hepatitis B. Hepatology. 26:1997;234-237.
    • (1997) Hepatology , vol.26 , pp. 234-237
    • Fontana, R.J.1    Lok Asf2
  • 125
    • 0342506489 scopus 로고    scopus 로고
    • Treatment of hepatitis B-related polyartcritis nodosa with famciclovir and interferon alfa-2b
    • Kruger M, Baker KHW, Zeidler H, Manns MP. Treatment of hepatitis B-related polyartcritis nodosa with famciclovir and interferon alfa-2b. J Hepatol. 26:1997;935-939.
    • (1997) J Hepatol , vol.26 , pp. 935-939
    • Kruger, M.1    Baker Khw2    Zeidler, H.3    Manns, M.P.4
  • 126
    • 0002238052 scopus 로고    scopus 로고
    • Lamivudine and intron A combination treatment in patients with chronic hepatitis B infection
    • Heathcote J, Schalm SW, Cianciara J, Farrell G, Feinmann V, Shermann M, et al. Lamivudine and intron A combination treatment in patients with chronic hepatitis B infection. J Hepatol. 28:(Suppl 1):1998;43.
    • (1998) J Hepatol , vol.28 , Issue.SUPPL. 1 , pp. 43
    • Heathcote, J.1    Schalm, S.W.2    Cianciara, J.3    Farrell, G.4    Feinmann, V.5    Shermann, M.6
  • 127
    • 0344624566 scopus 로고    scopus 로고
    • Mutations in"B domain" of polymerase gene during combination therapy of thymosin α-1 and famciclovir in immunotolerant Chinese chronic HBV carriers
    • In press
    • Lau GKK, Hou JL, Bartholomeusz A, Wang ZH, Sun J, Locarnini S. Mutations in"B domain" of polymerase gene during combination therapy of thymosin α-1 and famciclovir in immunotolerant Chinese chronic HBV carriers. Hepatology. 28:(4Pt2):1998;. In press.
    • (1998) Hepatology , vol.28 , Issue.4 PART 2
    • Lau Gkk1    Hou, J.L.2    Bartholomeusz, A.3    Wang Zh4    Sun, J.5    Locarnini, S.6


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