Generation of a library of 4-thiazolidinones utilizing Polymer Supported Quench (PSQ) reagent methodology

Biotechnology and Bioengineering

Volumn 61, Issue 1, 1998, Pages 17-22

  Ault Justus, Stephanie E ^a   Hodges, John C ^a   Wilson, Michael W ^a  

^a PFIZER INC   (United States)

Author keywords

4 thiazolidinones; Combinatorial library; Polymer supported quench

Indexed keywords

AGENTS; AMINES; AROMATIC COMPOUNDS; BIOSYNTHESIS; COPOLYMERS; FILTRATION; KETONES; POLYSTYRENES; SULFUR COMPOUNDS; VINYL RESINS;

BIOFILTRATION; SOLUTION PHASE SYNTHESIS; THIAZOLIDINONES;

DRUG PRODUCTS;

4 THIAZOLIDINONE DERIVATIVE; MERCAPTAMINE; POLY(STYRENE CO DIVINYLBENZENE); POLYMER; TRIS(2 AMINOETHYL)AMINE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHODOLOGY; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0032403246     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(199824)61:1<17::AID-BIT6>3.0.CO;2-1     Document Type: Article

References (22)

1. Armstrong, R. W.; Keating, T. A. J. Am. Chem. Soc. 1996, 118, 2574-2581.
2. Boger, D. L.; Tarby, C. M.; Myers, P. L.; Caporale, L. H. J. Am. Chem. Soc. 1996, 118, 2109-2110.
3. Brown, F. C.; Jones, R. S.; Kent, M. Can. J. Chem. 1963, 41, 817-820.
4. Curran, D. P. Org. Chem. 1996, 9, 75-87.
5. Ellman, J. A.; Bunin, B. A. J. Am. Chem. Soc. 1992, 114, 10997-10998.
6. Ellman, J. A.; Bunin, B. A.; Plunkett, M. J. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 4708-4712.
7. Ellman, J. A.; Plunkett, M. J. J. Am. Chem. Soc. 1995, 117, 3306-3307.
8. Ellman, J. A.; Plunkett, M. J. J. Org. Chem. 1995, 60, 6006-6007.
9. Ellman, J. A.; Thompson, L. A. Chem. Rev. 1996, 96, 555-600. And references therein.
10. Flynn, D. L.; Crich, J. Z.; Devraj, R. V.; Hockerman, S. L.; Parlow, J. J.; South, M. S.; Woodard, S. J. Am. Chem. Soc. 1997, 119, 4874-4881.
11. Gallop, M. A.; Barrett, R. W.; Dower, W. J.; Fodor, S. P. A.; Gordon, E. M. J. Med. Chem. 1994, 37, 1233-1251.
12. Gordon, E. M.; Barrett, R. W.; Dower, W. J.; Fodor, S. P. A.; Gallop, M. A. J. Med. Chem. 1994, 37, 1385-1400.
13. Hobbs DeWitt, S.; Kiely, J. S.; Stankovic, C. J.; Schroeder, M. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 6909-6913.
14. Hodges, J. C.; Booth, R. J. J. Am. Chem. 1997, 119, 4882-4886.
15. Holmes, C. P.; Chinn, J. P.; Look, G. C.; Gordon, E. M.; Gallop, M. A. J. Org. Chem. 1995, 60, 7328-7333.
16. Houghten, R. A.; Ostresh, J. M.; Husar, G. M.; Dorner, B.; Blondelle, S. E. Proc. Eur. Pept. Symp. 23rd: Leiden, The Netherlands, 1995, pp 459-460.
17. Hughes, I. Tetrahedron Lett. 1996, 37, 7595-7598.
18. Kaldor S.W.; Siegel, M. G.; Fritz, J. E.; Dressman, B. A.; Hahn, P. J. Tetrahedron Lett. 1996, 37, 7193-7196.
19. Rapoport, H.; Crowley, J. I. Acc. Chem. Res. 1976, 9, 135-144.
20. Rebek Jr., J.; Carell, T.; Winter, E. A.; Bashir-Hashemi, A. Angew. Chem. Int. Ed. Engl. 1994, 33, 2059-2061.
21. Suto, M. J.; Gayo, L. M. Tetrahedron Lett. 1997, 38, 513-516.
22. Veber, D. F.; Chenera, C.; Finkelstein, J. A. J. Am. Chem. Soc. 1995, 117, 11999-12000.