-
1
-
-
0028006612
-
Separation of oxidant-initiated and redox regulated steps in the NF-kβ signal transduction pathway
-
Anderson MT, Staal FJT, Gitler C, Herzenberg LA, Herzenberg LA. 1994. Separation of oxidant-initiated and redox regulated steps in the NF-kβ signal transduction pathway. Proc Natl Acad Sci USA 91:11527-11531.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11527-11531
-
-
Anderson, M.T.1
Staal, F.J.T.2
Gitler, C.3
Herzenberg, L.A.4
Herzenberg, L.A.5
-
2
-
-
0029878557
-
Mutagenesis of AS52 cells by low concentrations of lead(II) and mercury (II)
-
Ariza ME, Williams, MV. 1996. Mutagenesis of AS52 cells by low concentrations of lead(II) and mercury (II). Environ Mol Mutagen 27:30-33.
-
(1996)
Environ Mol Mutagen
, vol.27
, pp. 30-33
-
-
Ariza, M.E.1
Williams, M.V.2
-
3
-
-
0029039139
-
- in vascular smooth muscle cells
-
- in vascular smooth muscle cells. Circ Res 772:29-36.
-
(1995)
Circ Res
, vol.772
, pp. 29-36
-
-
Baas, A.S.1
Berk, B.C.2
-
4
-
-
0028174061
-
Function and activation of NF-kβ in the immune system
-
Baeuerle PA, Henkel T. 1994. Function and activation of NF-kβ in the immune system. Annu Rev Immunol 12:141-179.
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 141-179
-
-
Baeuerle, P.A.1
Henkel, T.2
-
5
-
-
0030728729
-
The antimutagenic and promutagenic activity of ascorbic acid during oxidative stress
-
Bijur GN, Ariza, ME, Hitchcock CL, Williams MV. 1997. The antimutagenic and promutagenic activity of ascorbic acid during oxidative stress. Environ Mol Mutagen 30:339-345.
-
(1997)
Environ Mol Mutagen
, vol.30
, pp. 339-345
-
-
Bijur, G.N.1
Ariza, M.E.2
Hitchcock, C.L.3
Williams, M.V.4
-
6
-
-
0029981099
-
cdc2 on Thr-14 and Tyr-15 at the prophase/metaphase transition
-
cdc2 on Thr-14 and Tyr-15 at the prophase/metaphase transition. J Biol Chem 271:27847-27854.
-
(1996)
J Biol Chem
, vol.271
, pp. 27847-27854
-
-
Borgne, A.1
Meijer, L.2
-
7
-
-
0028345161
-
Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells
-
Chen Q, Ames BN. 1994. Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. Proc Natl Acad Sci USA 91:4130-4134.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4130-4134
-
-
Chen, Q.1
Ames, B.N.2
-
8
-
-
0029051426
-
Oxidative DNA damage and senescence of human diploid fibroblast cells
-
Chen Q, Fischer A, Regan JD, Yan L-J, Ames BN. 1995. Oxidative DNA damage and senescence of human diploid fibroblast cells. Proc Natl Acad Sci USA 92:4337-4341.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4337-4341
-
-
Chen, Q.1
Fischer, A.2
Regan, J.D.3
Yan, L.-J.4
Ames, B.N.5
-
9
-
-
0029032154
-
Low-level oxidalive stress causes cell-cycle specific arrest in cultured cells
-
Clopton DA, Saltman P. 1995. Low-level oxidalive stress causes cell-cycle specific arrest in cultured cells. Biochem Biophys Res Commun 210:189-196.
-
(1995)
Biochem Biophys Res Commun
, vol.210
, pp. 189-196
-
-
Clopton, D.A.1
Saltman, P.2
-
10
-
-
0014932459
-
Dehydroascorbic acid and cell division
-
Edgar JA. 1970. Dehydroascorbic acid and cell division. Nature 227:24-26.
-
(1970)
Nature
, vol.227
, pp. 24-26
-
-
Edgar, J.A.1
-
11
-
-
0029808466
-
Cell cycle checkpoints: Preventing an identity crisis
-
Elledge SJ. 1996. Cell cycle checkpoints: preventing an identity crisis. Science 274:1664-1672.
-
(1996)
Science
, vol.274
, pp. 1664-1672
-
-
Elledge, S.J.1
-
12
-
-
0031044832
-
Redox regulation of NF-kappa B activation
-
Flohe L, Brigelius-Flohe R, Saliou C, Traber MG, Packer L. 1997. Redox regulation of NF-kappa B activation. Free Radic Biol Med 22: 1115-1126.
-
(1997)
Free Radic Biol Med
, vol.22
, pp. 1115-1126
-
-
Flohe, L.1
Brigelius-Flohe, R.2
Saliou, C.3
Traber, M.G.4
Packer, L.5
-
13
-
-
0026323320
-
Ascorbic acid protects against endogenous oxidative DNA damage in human sperm
-
Fraga CG, Motchnik PA, Shigenaga MK, Helbock HJ, Jacob RA, Ames, BN. 1991. Ascorbic acid protects against endogenous oxidative DNA damage in human sperm. Proc Natl Acad Sci USA 88:11003-11006.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 11003-11006
-
-
Fraga, C.G.1
Motchnik, P.A.2
Shigenaga, M.K.3
Helbock, H.J.4
Jacob, R.A.5
Ames, B.N.6
-
14
-
-
0024239038
-
Antioxidant defenses and lipid peroxidation in human blood plasma
-
Frei B, Stocker R, Ames BN. 1988. Antioxidant defenses and lipid peroxidation in human blood plasma. Proc Natl Acad Sci USA 85: 9748-9752.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 9748-9752
-
-
Frei, B.1
Stocker, R.2
Ames, B.N.3
-
15
-
-
0001218860
-
Ascorbate is an outstanding antioxidant in human blood plasma
-
Frei B, England L, Ames BN. 1989. Ascorbate is an outstanding antioxidant in human blood plasma. Proc Natl Acad Sci USA 86:6377-6381.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 6377-6381
-
-
Frei, B.1
England, L.2
Ames, B.N.3
-
16
-
-
0030768948
-
Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase
-
Furnari B, Rhind N, Russell P. 1997. Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase. Science 277:1495-1497.
-
(1997)
Science
, vol.277
, pp. 1495-1497
-
-
Furnari, B.1
Rhind, N.2
Russell, P.3
-
17
-
-
0018393389
-
Vitamin C is positive in the DNA synthesis inhibition and sister chromatid exchange test
-
Galloway SM, Painter RB. 1979. Vitamin C is positive in the DNA synthesis inhibition and sister chromatid exchange test. Mutat Res 60:321-327.
-
(1979)
Mutat Res
, vol.60
, pp. 321-327
-
-
Galloway, S.M.1
Painter, R.B.2
-
18
-
-
0028348239
-
Distinct effects of glutalhione disulfide on the nuclear transcription factors kβ and the activator protein-1
-
Galter D, Mihm S, Droge W. 1994. Distinct effects of glutalhione disulfide on the nuclear transcription factors kβ and the activator protein-1. Eur J Biochem 221:639-648.
-
(1994)
Eur J Biochem
, vol.221
, pp. 639-648
-
-
Galter, D.1
Mihm, S.2
Droge, W.3
-
19
-
-
0028843145
-
Sites and mechanisms of low-level oxidative stress in cultured cells
-
Gelvan D, Moreno V, Clopton DA, Chen Q, Saltman P. 1995. Sites and mechanisms of low-level oxidative stress in cultured cells. Biochem Biophys Res Commun 206:421-428.
-
(1995)
Biochem Biophys Res Commun
, vol.206
, pp. 421-428
-
-
Gelvan, D.1
Moreno, V.2
Clopton, D.A.3
Chen, Q.4
Saltman, P.5
-
20
-
-
0020444895
-
Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis
-
Griffith OW. 1982. Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis. J Biol Chem 257:13704-13712.
-
(1982)
J Biol Chem
, vol.257
, pp. 13704-13712
-
-
Griffith, O.W.1
-
22
-
-
0027509501
-
Phosphorylation and activation of human cdc25-C by cdc2-cyclin B and its involvement in the self-amplification of MPF at mitosis
-
Hoffmann I, Clarke PR, Marcote MJ, Karsenti E, Draetta G. 1992. Phosphorylation and activation of human cdc25-C by cdc2-cyclin B and its involvement in the self-amplification of MPF at mitosis. EMBO J 11:53-63.
-
(1992)
EMBO J
, vol.11
, pp. 53-63
-
-
Hoffmann, I.1
Clarke, P.R.2
Marcote, M.J.3
Karsenti, E.4
Draetta, G.5
-
23
-
-
0027297641
-
Ascorbic acid enhances forskolin-induced cyclic AMP production and Pro-ANF mRNA expression of hypothalamic neurons in culture
-
Huang W, Yang L, Lee D, Copolov DL, Lim AT. 1993. Ascorbic acid enhances forskolin-induced cyclic AMP production and Pro-ANF mRNA expression of hypothalamic neurons in culture. Endocrinology 132:2271-2273.
-
(1993)
Endocrinology
, vol.132
, pp. 2271-2273
-
-
Huang, W.1
Yang, L.2
Lee, D.3
Copolov, D.L.4
Lim, A.T.5
-
24
-
-
0030980641
-
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
-
Irani K, Xia Y, Zweier JL, Sollott SJ, Der CJ, Fearon JL, Sundaresan M, Finkel T, Goldschmidt-Clermont PJ. 1997. Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science 275: 1649-1652.
-
(1997)
Science
, vol.275
, pp. 1649-1652
-
-
Irani, K.1
Xia, Y.2
Zweier, J.L.3
Sollott, S.J.4
Der, C.J.5
Fearon, J.L.6
Sundaresan, M.7
Finkel, T.8
Goldschmidt-Clermont, P.J.9
-
25
-
-
0027199077
-
Micronutrients and their influence on mutagenicity and malignant transformation
-
Krinsky NI. 1993. Micronutrients and their influence on mutagenicity and malignant transformation. Ann NY Acad Sci 686:229-242.
-
(1993)
Ann NY Acad Sci
, vol.686
, pp. 229-242
-
-
Krinsky, N.I.1
-
26
-
-
0022529472
-
Inhibition of cyclophosphamide and mitomycin C induced sister chromatid exchanges in mice by vitamin C
-
Krishna G, Nath J, Ong T. 1986. Inhibition of cyclophosphamide and mitomycin C induced sister chromatid exchanges in mice by vitamin C. Cancer Res 46:2670-2674.
-
(1986)
Cancer Res
, vol.46
, pp. 2670-2674
-
-
Krishna, G.1
Nath, J.2
Ong, T.3
-
27
-
-
0025980359
-
The cdc25 protein controls tyrosine dephosphorylation of the cdc2 protein in a cell free system
-
Kumugai A, Dunphy WG. 1991. The cdc25 protein controls tyrosine dephosphorylation of the cdc2 protein in a cell free system. Cell 64:903-914.
-
(1991)
Cell
, vol.64
, pp. 903-914
-
-
Kumugai, A.1
Dunphy, W.G.2
-
28
-
-
0024325259
-
Ascorbic acid induces alkaline phosphatase, type X collagen, and calcium deposition in cultured chick chondrocytes
-
Leboy PS, Vaias L, Uschmann B, Golub E, Adams SL, Pacifici M. 1989. Ascorbic acid induces alkaline phosphatase, type X collagen, and calcium deposition in cultured chick chondrocytes. J Biol Chem 264:17281-17286.
-
(1989)
J Biol Chem
, vol.264
, pp. 17281-17286
-
-
Leboy, P.S.1
Vaias, L.2
Uschmann, B.3
Golub, E.4
Adams, S.L.5
Pacifici, M.6
-
29
-
-
0021760872
-
Ascorbate stimulation of PAT cells causes an increase in transcription rates and a decrease in degradation of procollagen mRNA
-
Lyons BL, Schwarz RI. 1984. Ascorbate stimulation of PAT cells causes an increase in transcription rates and a decrease in degradation of procollagen mRNA. Nucleic Acids Res 12:2569-2579.
-
(1984)
Nucleic Acids Res
, vol.12
, pp. 2569-2579
-
-
Lyons, B.L.1
Schwarz, R.I.2
-
30
-
-
0025917804
-
p55cdc25 is a nuclear protein required for the initiation of mitosis in human cells
-
Millar JBA, Blevit J, Gerace L, Sadh K, Featherstone C, Russell P. 1991. p55cdc25 is a nuclear protein required for the initiation of mitosis in human cells. Proc Natl Acad Sci USA 88:10500-10504.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 10500-10504
-
-
Millar, J.B.A.1
Blevit, J.2
Gerace, L.3
Sadh, K.4
Featherstone, C.5
Russell, P.6
-
31
-
-
0028931265
-
Principles of CDK regulation
-
Morgan DO. 1995. Principles of CDK regulation. Nature 374:131-134.
-
(1995)
Nature
, vol.374
, pp. 131-134
-
-
Morgan, D.O.1
-
32
-
-
0025719364
-
Action of ascorbic acid us a scavenger of active and stable oxygen radicals
-
Niki R. 1991. Action of ascorbic acid us a scavenger of active and stable oxygen radicals. Am J Clin Nutr 54:1119S-1124S.
-
(1991)
Am J Clin Nutr
, vol.54
-
-
Niki, R.1
-
33
-
-
0030611095
-
Mitotic and G2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of cdc25C on serine-216
-
Peng C-Y, Graves PR, Thoma RS, Wu Z, Shaw AS, Piwnica-Worms H. 1997. Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of cdc25C on serine-216. Science 277:1501-1505.
-
(1997)
Science
, vol.277
, pp. 1501-1505
-
-
Peng, C.-Y.1
Graves, P.R.2
Thoma, R.S.3
Wu, Z.4
Shaw, A.S.5
Piwnica-Worms, H.6
-
34
-
-
0030665150
-
The role of cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells
-
Poon RYC, Chau MS, Yamaschit, K, Hunter T. 1997. The role of cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells. Cancer Res 57:5168-5178.
-
(1997)
Cancer Res
, vol.57
, pp. 5168-5178
-
-
Poon, R.Y.C.1
Chau, M.S.2
Yamaschit, K.3
Hunter, T.4
-
35
-
-
0018872455
-
Mutagenic activity of ascorbate in mammalian cell cultures
-
Rosin MP, San RHC, Stich HF. 1980. Mutagenic activity of ascorbate in mammalian cell cultures. Cancer Lett 8:299-305.
-
(1980)
Cancer Lett
, vol.8
, pp. 299-305
-
-
Rosin, M.P.1
San, R.H.C.2
Stich, H.F.3
-
36
-
-
0030867582
-
Conservation of the chk1 checkpoint pathway in mammals: Linkage of DNA damage to cdk regulation through cdc25
-
Sanchez, Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, Elledge SJ. 1997. Conservation of the chk1 checkpoint pathway in mammals: linkage of DNA damage to cdk regulation through cdc25. Science 277:1497-1501.
-
(1997)
Science
, vol.277
, pp. 1497-1501
-
-
Sanchez, Y.1
Wong, C.2
Thoma, R.S.3
Richman, R.4
Wu, Z.5
Piwnica-Worms, H.6
Elledge, S.J.7
-
38
-
-
0028344541
-
Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-kβ and AP-1
-
Schenk H, Klein M, Erdbrugger W, Droge W, Schulze-Osthoff K. 1994. Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-kβ and AP-1. Proc Natl Acad Sci USA 91:1672-1676.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 1672-1676
-
-
Schenk, H.1
Klein, M.2
Erdbrugger, W.3
Droge, W.4
Schulze-Osthoff, K.5
-
39
-
-
0029984062
-
Antioxidant and redox regulation of gene transcription
-
Sen CK, Packer L. 1996. Antioxidant and redox regulation of gene transcription. FASEB J 10:709-720.
-
(1996)
FASEB J
, vol.10
, pp. 709-720
-
-
Sen, C.K.1
Packer, L.2
-
40
-
-
0021354607
-
Genetic toxicology of ascorbic acid
-
Shamberger RJ. 1984. Genetic toxicology of ascorbic acid. Mutat Res 133:135-159.
-
(1984)
Mutat Res
, vol.133
, pp. 135-159
-
-
Shamberger, R.J.1
-
41
-
-
0018885770
-
The SCE inducing capacity of vitamin C: Investigations in vitro and in vivo
-
Speit G, Wolf M, Vogel W. 1980. The SCE inducing capacity of vitamin C: investigations in vitro and in vivo. Mutat Res 78:273-278.
-
(1980)
Mutat Res
, vol.78
, pp. 273-278
-
-
Speit, G.1
Wolf, M.2
Vogel, W.3
-
42
-
-
0028053726
-
Modulation of activator protein-21 (AP-1) transcription factor and protein kinase C by hydrogen peroxide and D-tocopherol in vascular smooth muscle cells
-
Stauble B, Boscoboinki D, Tasinato A, Azzi A. 1994. Modulation of activator protein-21 (AP-1) transcription factor and protein kinase C by hydrogen peroxide and D-tocopherol in vascular smooth muscle cells. Eur J Biochem 226:393-402.
-
(1994)
Eur J Biochem
, vol.226
, pp. 393-402
-
-
Stauble, B.1
Boscoboinki, D.2
Tasinato, A.3
Azzi, A.4
-
44
-
-
0018601923
-
Enhancement of the chromosome damaging action of ascorbate by transition metals
-
Stich HF, Wei L, Whiting RF. 1979. Enhancement of the chromosome damaging action of ascorbate by transition metals. Cancer Res 39:4145-4151.
-
(1979)
Cancer Res
, vol.39
, pp. 4145-4151
-
-
Stich, H.F.1
Wei, L.2
Whiting, R.F.3
-
45
-
-
0029810269
-
Cell cycle control of DNA replication
-
Stillman B. 1996. Cell cycle control of DNA replication. Science 274: 1659-1664.
-
(1996)
Science
, vol.274
, pp. 1659-1664
-
-
Stillman, B.1
-
46
-
-
0028021760
-
Ascorbate modulation of chondrocyte gene expression is independent of its role in collagen secretion
-
Sullivan TA, Uschmann B, Hough R, Leboy PS. 1994. Ascorbate modulation of chondrocyte gene expression is independent of its role in collagen secretion. J Biol Chem 269:22500-22506.
-
(1994)
J Biol Chem
, vol.269
, pp. 22500-22506
-
-
Sullivan, T.A.1
Uschmann, B.2
Hough, R.3
Leboy, P.S.4
-
47
-
-
0031050629
-
Effect of antioxidant supplementation on DNA damage and repair in human lymphoblastoid cells
-
Sweetman SF, Strain JJ, McKelvey-Martin VJ. 1997. Effect of antioxidant supplementation on DNA damage and repair in human lymphoblastoid cells. Nutr Cancer 27:122-130.
-
(1997)
Nutr Cancer
, vol.27
, pp. 122-130
-
-
Sweetman, S.F.1
Strain, J.J.2
McKelvey-Martin, V.J.3
-
48
-
-
0027302594
-
Mammalian facilitative hexose transporters mediate the transport of dehydroascorbate
-
Vera JC, Rivas CI, Fischbarg J, Golde DW. 1993. Mammalian facilitative hexose transporters mediate the transport of dehydroascorbate. Nature 364:79-82.
-
(1993)
Nature
, vol.364
, pp. 79-82
-
-
Vera, J.C.1
Rivas, C.I.2
Fischbarg, J.3
Golde, D.W.4
-
49
-
-
0028853597
-
Resolution of the facilitated transport of dehydroascorbic acid from its intracellular accumulation as ascorbic acid
-
Vera JC, Rivas CI, Velasquez FV, Zhang RH, Concha II, Golde DW. 1995. Resolution of the facilitated transport of dehydroascorbic acid from its intracellular accumulation as ascorbic acid. J Biol Chem 270: 23706-23713.
-
(1995)
J Biol Chem
, vol.270
, pp. 23706-23713
-
-
Vera, J.C.1
Rivas, C.I.2
Velasquez, F.V.3
Zhang, R.H.4
Concha, I.I.5
Golde, D.W.6
-
50
-
-
0027248971
-
Ascorbic acid accumulation and transport in human fibroblasts
-
Welch RW, Bergsten P, Butler JD, Levine M. 1993. Ascorbic acid accumulation and transport in human fibroblasts. Biochem J 294:505-510.
-
(1993)
Biochem J
, vol.294
, pp. 505-510
-
-
Welch, R.W.1
Bergsten, P.2
Butler, J.D.3
Levine, M.4
-
51
-
-
0029015720
-
Accumulation of vitamin C (ascorbate) and its oxidized metabolite dehydroascorbic acid occurs by separate mechanisms
-
Welch RW, Wang Y, Crossman A, Park JB, Kirk KL, Levine M. 1995. Accumulation of vitamin C (ascorbate) and its oxidized metabolite dehydroascorbic acid occurs by separate mechanisms. J Biol Chem 270:12584-12592.
-
(1995)
J Biol Chem
, vol.270
, pp. 12584-12592
-
-
Welch, R.W.1
Wang, Y.2
Crossman, A.3
Park, J.B.4
Kirk, K.L.5
Levine, M.6
-
52
-
-
0028825966
-
Cell cycle constraints on peroxide- and radiation-induced inhibitory checkpoint
-
Wharton W. 1995. Cell cycle constraints on peroxide- and radiation-induced inhibitory checkpoint. Cancer Res 55:5069-5074.
-
(1995)
Cancer Res
, vol.55
, pp. 5069-5074
-
-
Wharton, W.1
|