메뉴 건너뛰기




Volumn 18, Issue 11, 1996, Pages 919-923

The vagaries of variegating transgenes

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; MUS MUSCULUS;

EID: 0030298416     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.950181111     Document Type: Review
Times cited : (143)

References (46)
  • 1
    • 0022965278 scopus 로고
    • Germ-line transformation of mice
    • Palmiter, R.D. and Brinster, R.L. (1986). Germ-line transformation of mice. Ann. Rev. Genet. 20, 465-499.
    • (1986) Ann. Rev. Genet. , vol.20 , pp. 465-499
    • Palmiter, R.D.1    Brinster, R.L.2
  • 2
    • 0023663887 scopus 로고
    • Position-independent, high-level expression of the human β-globin gene in transgenic mice
    • Grosveld, F., van Assendelft, G.B., Greaves, D. and Kollias, G. (1987). Position-independent, high-level expression of the human β-globin gene in transgenic mice. Cell 51, 975-985.
    • (1987) Cell , vol.51 , pp. 975-985
    • Grosveld, F.1    Van Assendelft, G.B.2    Greaves, D.3    Kollias, G.4
  • 3
    • 0027014049 scopus 로고
    • Position effect and related phenomena
    • Henikoff, S. (1992). Position effect and related phenomena. Curr. Opin. Genet. Dev. 2, 907-912.
    • (1992) Curr. Opin. Genet. Dev. , vol.2 , pp. 907-912
    • Henikoff, S.1
  • 4
    • 0002434883 scopus 로고
    • The phenomenon of position effect
    • Lewis, E.B. (1950) The phenomenon of position effect. Adv. Genet. 3, 73-115.
    • (1950) Adv. Genet. , vol.3 , pp. 73-115
    • Lewis, E.B.1
  • 5
    • 0026004634 scopus 로고
    • Mosaic expression of a tyrosinase fusion gene in albino mice yields a heritable striped coat color pattern in transgene homozygotes
    • Mintz, B. and Bradl, M. (1991). Mosaic expression of a tyrosinase fusion gene in albino mice yields a heritable striped coat color pattern in transgene homozygotes Proc. Natl Acad. Sci. USA 88, 9643-9647.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 9643-9647
    • Mintz, B.1    Bradl, M.2
  • 6
    • 0023770931 scopus 로고
    • Conversion of normal behavior to shiverer by myelin basic protein antisense cDNA in transgenic mice
    • Katsuki, M., Sato, M., Kimura, M., Yokoyama, K., Kobayashi, K. and Nomura, T. (1988). Conversion of normal behavior to shiverer by myelin basic protein antisense cDNA in transgenic mice. Science 241, 593-595.
    • (1988) Science , vol.241 , pp. 593-595
    • Katsuki, M.1    Sato, M.2    Kimura, M.3    Yokoyama, K.4    Kobayashi, K.5    Nomura, T.6
  • 7
    • 0004341822 scopus 로고
    • Transgenic mice containing intestinal fatty acid-binding protein-human growth hormone fusion genes exhibit correct regional and cell-specific expression of the reporter gene in their small intestine
    • Sweetser, D., Hauft, S., Hoppe, P., Birkenmeir, E. and Gordon, J. (1988). Transgenic mice containing intestinal fatty acid-binding protein-human growth hormone fusion genes exhibit correct regional and cell-specific expression of the reporter gene in their small intestine. Proc. Natl Acad. Sci. USA 85, 9611-9615.
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 9611-9615
    • Sweetser, D.1    Hauft, S.2    Hoppe, P.3    Birkenmeir, E.4    Gordon, J.5
  • 8
    • 0029912235 scopus 로고    scopus 로고
    • Locus control region function and heterochromatin-induced position effect variegation
    • Festenstein, R. et al. (1996). Locus control region function and heterochromatin-induced position effect variegation. Science 271, 1123-1125.
    • (1996) Science , vol.271 , pp. 1123-1125
    • Festenstein, R.1
  • 9
    • 0024758382 scopus 로고
    • Cellular mosaicism in the methylation and expression of hemizygous loci in the mouse
    • McGowan, R., Campbell, B., Peterson, A. and Sapienza, C. (1989). Cellular mosaicism in the methylation and expression of hemizygous loci in the mouse. Genes Dev. 3, 1669-1676.
    • (1989) Genes Dev. , vol.3 , pp. 1669-1676
    • McGowan, R.1    Campbell, B.2    Peterson, A.3    Sapienza, C.4
  • 10
    • 0028430999 scopus 로고
    • Mosaic expression of an HPRT transgene integrated in a region of Y heterochromatin
    • Pravtcheva, D.D., Wise, T.L., Ensor, N.J. and Ruddle, F.H. (1994). Mosaic expression of an HPRT transgene integrated in a region of Y heterochromatin. J. Exp. Zool. 268, 452-468.
    • (1994) J. Exp. Zool. , vol.268 , pp. 452-468
    • Pravtcheva, D.D.1    Wise, T.L.2    Ensor, N.J.3    Ruddle, F.H.4
  • 12
    • 0024281345 scopus 로고
    • DNA methylation and gene activity
    • Cedar, H. (1988). DNA methylation and gene activity. Cell 53, 3-4.
    • (1988) Cell , vol.53 , pp. 3-4
    • Cedar, H.1
  • 13
    • 0016299216 scopus 로고
    • Position effect variegation in the mouse
    • Cattanach, B.M. (1974). Position effect variegation in the mouse. Genet. Res., Camb. 23, 291-306.
    • (1974) Genet. Res., Camb. , vol.23 , pp. 291-306
    • Cattanach, B.M.1
  • 14
    • 0027312789 scopus 로고
    • Polyhomeotic regulatory sequences induce developmental regulator-dependent variegation and targeted P-element insertion in Drosophila
    • Fauvarque, M.-O. and Dura, J.-M. (1993). Polyhomeotic regulatory sequences induce developmental regulator-dependent variegation and targeted P-element insertion in Drosophila. Genes Dev. 7, 1508-1520.
    • (1993) Genes Dev. , vol.7 , pp. 1508-1520
    • Fauvarque, M.-O.1    Dura, J.-M.2
  • 15
    • 0028881923 scopus 로고
    • A developmentally regulated position effect at a telomeric locus in Trypanosoma brucei
    • Horn, D. and Cross, G.A.M. (1995). A developmentally regulated position effect at a telomeric locus in Trypanosoma brucei. Cell 83, 555-561.
    • (1995) Cell , vol.83 , pp. 555-561
    • Horn, D.1    Cross, G.A.M.2
  • 16
    • 0028485216 scopus 로고
    • White gene expression, repressive chromatin domains and homeotic gene regulation in Drosophila
    • Pirrotta, V. and Rastelli, L. (1994). White gene expression, repressive chromatin domains and homeotic gene regulation in Drosophila. BioEssays 16, 549-556.
    • (1994) BioEssays , vol.16 , pp. 549-556
    • Pirrotta, V.1    Rastelli, L.2
  • 17
    • 0026845839 scopus 로고
    • Silencing: The establishment and inheritance of stable, repressed transcriptional states
    • Rivier, D.H. and Rine, J. (1992). Silencing: the establishment and inheritance of stable, repressed transcriptional states. Curr. Opin. Genet. Dev. 2, 286-292.
    • (1992) Curr. Opin. Genet. Dev. , vol.2 , pp. 286-292
    • Rivier, D.H.1    Rine, J.2
  • 18
    • 0028809565 scopus 로고
    • A ribosomal DNA promoter replacing the promoter of a telomeric VSG gene expression site can be efficiently switched on and off in T. brucei
    • Rudenko, G., Blundell, P.A., Dirks-Mulder, A., Kieft, R. and Borst, P. (1995). A ribosomal DNA promoter replacing the promoter of a telomeric VSG gene expression site can be efficiently switched on and off in T. brucei. Cell 83, 547-553.
    • (1995) Cell , vol.83 , pp. 547-553
    • Rudenko, G.1    Blundell, P.A.2    Dirks-Mulder, A.3    Kieft, R.4    Borst, P.5
  • 19
    • 0028011256 scopus 로고
    • Position effect variegation at fission yeast centromeres
    • Allshire, R.C., Javerzat, J.-P., Redhead, N.J. and Cranston, G. (1994). Position effect variegation at fission yeast centromeres. Cell 76, 157-169.
    • (1994) Cell , vol.76 , pp. 157-169
    • Allshire, R.C.1    Javerzat, J.-P.2    Redhead, N.J.3    Cranston, G.4
  • 20
    • 0029130085 scopus 로고
    • Propagating memory of transcriptional states
    • Paro, R. (1995). Propagating memory of transcriptional states. Trends Genet. 118, 295-297.
    • (1995) Trends Genet. , vol.118 , pp. 295-297
    • Paro, R.1
  • 21
    • 0027184524 scopus 로고
    • Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage
    • Renauld, H. et al. (1993) Silent domains are assembled continuously from the telomere and are defined by promoter distance and strength, and by SIR3 dosage. Genes Dev. 7, 1133-1145.
    • (1993) Genes Dev. , vol.7 , pp. 1133-1145
    • Renauld, H.1
  • 22
    • 0030028985 scopus 로고    scopus 로고
    • Transcriptional enhancers act in cis to suppress position-effect variegation
    • Walters, M.C. et al. (1996). Transcriptional enhancers act in cis to suppress position-effect variegation. Genes Dev. 10, 185-195.
    • (1996) Genes Dev. , vol.10 , pp. 185-195
    • Walters, M.C.1
  • 23
    • 0029937208 scopus 로고    scopus 로고
    • Genetic modification of heterochromatic association and nuclear organization in Drosophila
    • Csink, A.K. and Henikoff, S. (1996). Genetic modification of heterochromatic association and nuclear organization in Drosophila. Nature 381, 529-531.
    • (1996) Nature , vol.381 , pp. 529-531
    • Csink, A.K.1    Henikoff, S.2
  • 24
    • 0022820777 scopus 로고
    • Varied interactions between proviruses and adjacent host chromatin
    • Conklin, K.F. and Groudine, M. (1986). Varied interactions between proviruses and adjacent host chromatin. Mol. Cell. Biol. 6, 3999-4007.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 3999-4007
    • Conklin, K.F.1    Groudine, M.2
  • 25
    • 0020404925 scopus 로고
    • Modulation of transfected gene expression mediated by changes in chromatin structure
    • Davies, R.L., Fuhrer-Krusi, S. and Kucherlapati, R.S. (1982). Modulation of transfected gene expression mediated by changes in chromatin structure. Cell 31, 521-529.
    • (1982) Cell , vol.31 , pp. 521-529
    • Davies, R.L.1    Fuhrer-Krusi, S.2    Kucherlapati, R.S.3
  • 26
    • 0020328341 scopus 로고
    • Chromosomal position effects determine transcriptional potential of integrated mammary tumor virus DNA
    • Feinstein, S.C., Ross, S.R. and Yamamoto, K.R. (1982). Chromosomal position effects determine transcriptional potential of integrated mammary tumor virus DNA. J. Mol. Biol. 156, 549-565.
    • (1982) J. Mol. Biol. , vol.156 , pp. 549-565
    • Feinstein, S.C.1    Ross, S.R.2    Yamamoto, K.R.3
  • 27
    • 0028321783 scopus 로고
    • A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression
    • Chan, C.-S., Rastelli, L. and Pirotta, V. (1994). A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression. EMBO J. 13, 2553-2564.
    • (1994) EMBO J. , vol.13 , pp. 2553-2564
    • Chan, C.-S.1    Rastelli, L.2    Pirotta, V.3
  • 28
    • 0025294924 scopus 로고
    • Epigenetic changes in the expression of the maize A1 gene of Petunia hybrida: Role of numbers of integrated gene copies and state of methylation
    • Linn, E., Heidmann, I., Saedler, H. and Meyer, P. (1990). Epigenetic changes in the expression of the maize A1 gene of Petunia hybrida: role of numbers of integrated gene copies and state of methylation. Mol. Gen. Genet. 222, 329-336.
    • (1990) Mol. Gen. Genet. , vol.222 , pp. 329-336
    • Linn, E.1    Heidmann, I.2    Saedler, H.3    Meyer, P.4
  • 29
    • 0028286165 scopus 로고
    • Expansions of transgene repeats cause heterochromatin formation and gene silencing in Drosophila
    • Dorer, D.R. and Henikoff, S. (1994). Expansions of transgene repeats cause heterochromatin formation and gene silencing in Drosophila. Cell 77, 1-20.
    • (1994) Cell , vol.77 , pp. 1-20
    • Dorer, D.R.1    Henikoff, S.2
  • 30
    • 85035184581 scopus 로고    scopus 로고
    • Do transgene arrays form heterochromatin in vertebrates?
    • in press
    • Dorer, D. (1996). Do transgene arrays form heterochromatin in vertebrates? Transgene Res. (in press).
    • (1996) Transgene Res.
    • Dorer, D.1
  • 31
    • 0023673729 scopus 로고
    • Limited transcription of rat elastase I transgene repeats in transgenic mice
    • Davis, B. and McDonald, R.J. (1988). Limited transcription of rat elastase I transgene repeats in transgenic mice. Genes Dev. 2, 13-22.
    • (1988) Genes Dev. , vol.2 , pp. 13-22
    • Davis, B.1    McDonald, R.J.2
  • 32
    • 0028029838 scopus 로고
    • Analysis of a 70 kb segment of DNA containing the human z and a globin genes linked to their regulatory element (HS-40) in transgenic mice
    • Gourdon, G., Sharpe, J., Wells, D., Wood, W. and Higgs, D. (1994). Analysis of a 70 kb segment of DNA containing the human z and a globin genes linked to their regulatory element (HS-40) in transgenic mice. Nucl. Acids Res. 22, 4139-4147.
    • (1994) Nucl. Acids Res. , vol.22 , pp. 4139-4147
    • Gourdon, G.1    Sharpe, J.2    Wells, D.3    Wood, W.4    Higgs, D.5
  • 34
    • 0029874533 scopus 로고    scopus 로고
    • Age-dependent silencing of globin transgene expresion in the mouse
    • Robertson, G., Garrick, D., Wilson, M., Martin, D. and Whitelaw, E. (1996). Age-dependent silencing of globin transgene expresion in the mouse. Nucl. Acids Res. 24, 1465-1471.
    • (1996) Nucl. Acids Res. , vol.24 , pp. 1465-1471
    • Robertson, G.1    Garrick, D.2    Wilson, M.3    Martin, D.4    Whitelaw, E.5
  • 35
    • 0028260976 scopus 로고
    • Overcoming telomeric silencing: A trans-activator competes to establish gene expression in a cell cycle-dependent way
    • Aparicio, O.M. and Gottschling, D.E. (1994). Overcoming telomeric silencing: a trans-activator competes to establish gene expression in a cell cycle-dependent way. Genes Dev. 8, 1133-1146.
    • (1994) Genes Dev. , vol.8 , pp. 1133-1146
    • Aparicio, O.M.1    Gottschling, D.E.2
  • 36
    • 0001823437 scopus 로고
    • The biology of heterochromatin
    • (ed. R. S. Verma), Cambridge, Cambridge University Press
    • John, B. (1988). The biology of heterochromatin. In Heterochromatin: Molecular and Structural Aspects (ed. R. S. Verma), pp. 1-147. Cambridge, Cambridge University Press.
    • (1988) Heterochromatin: Molecular and Structural Aspects , pp. 1-147
    • John, B.1
  • 37
    • 0023118991 scopus 로고
    • Macromolecular synthesis and degradation during terminal erythroid cell development
    • Bonanou-Tzedaki, S.A. and Arnstein, H.R.V. (1987). Macromolecular synthesis and degradation during terminal erythroid cell development. Biomed. Biochim. Act. 46, 121-149.
    • (1987) Biomed. Biochim. Act. , vol.46 , pp. 121-149
    • Bonanou-Tzedaki, S.A.1    Arnstein, H.R.V.2
  • 38
    • 0027944303 scopus 로고
    • Analysis of the developmental and transcriptional potentiation functions of 5′ HS2 of the murine β-globin locus control region in transgenic mice
    • Enver T. et al. (1994). Analysis of the developmental and transcriptional potentiation functions of 5′ HS2 of the murine β-globin locus control region in transgenic mice. Devel. Biol. 165, 574-584.
    • (1994) Devel. Biol. , vol.165 , pp. 574-584
    • Enver, T.1
  • 39
    • 0027367941 scopus 로고
    • Developmental regulation of human gamma-globin genes in transgenic mice
    • Stamatoyannopoulos, G., Josephson, B., Zhang, J.W. and Li, Q. (1993). Developmental regulation of human gamma-globin genes in transgenic mice. Mol. Cell. Biol. 13, 7636-7644.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7636-7644
    • Stamatoyannopoulos, G.1    Josephson, B.2    Zhang, J.W.3    Li, Q.4
  • 40
    • 0026928683 scopus 로고
    • Position effect variegation and chromatin proteins
    • Reuter, G. and Spierer, P. (1992). Position effect variegation and chromatin proteins. BioEssays 14, 605-612.
    • (1992) BioEssays , vol.14 , pp. 605-612
    • Reuter, G.1    Spierer, P.2
  • 41
    • 0030136596 scopus 로고    scopus 로고
    • Dosage-dependent modification of position-effect variegation in Drosophila
    • Henikoff, S. (1996). Dosage-dependent modification of position-effect variegation in Drosophila. BioEssays 18, 401-409.
    • (1996) BioEssays , vol.18 , pp. 401-409
    • Henikoff, S.1
  • 42
    • 0028847640 scopus 로고
    • Random inactivation of a transgene under the control of a hybrid hCD2 locus control region/Ig enhancer regulatory element
    • Elliot, J.I., Festenstein, R., Tolalni, M. and Kioussis, D. (1995). Random inactivation of a transgene under the control of a hybrid hCD2 locus control region/Ig enhancer regulatory element. EMBO J. 14, 575-584.
    • (1995) EMBO J. , vol.14 , pp. 575-584
    • Elliot, J.I.1    Festenstein, R.2    Tolalni, M.3    Kioussis, D.4
  • 43
    • 0026093253 scopus 로고
    • A sequence motif found in a Drosophila heterochromatin protein is conserved in animals and plants
    • Singh, P.B. et al. (1991). A sequence motif found in a Drosophila heterochromatin protein is conserved in animals and plants. Nucl. Acids Res. 19, 789-794.
    • (1991) Nucl. Acids Res. , vol.19 , pp. 789-794
    • Singh, P.B.1
  • 44
    • 0026594541 scopus 로고
    • The mouse has a Polycomb-like chromobox gene
    • Pearce, J.J.H., Singh, P.B. and Gaunt, S.J. (1992). The mouse has a Polycomb-like chromobox gene. Devetopment 114, 921-929.
    • (1992) Devetopment , vol.114 , pp. 921-929
    • Pearce, J.J.H.1    Singh, P.B.2    Gaunt, S.J.3
  • 46
    • 0027490840 scopus 로고
    • Paramutation, an allelic interaction, is associated with a stable and heritable reduction of transcription of the maize b regulatory gene
    • Patterson, G.I., Thorpe, C.J. and Chandler, V.L. (1993). Paramutation, an allelic interaction, is associated with a stable and heritable reduction of transcription of the maize b regulatory gene. Genetics 135, 881-894.
    • (1993) Genetics , vol.135 , pp. 881-894
    • Patterson, G.I.1    Thorpe, C.J.2    Chandler, V.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.