Adaptor proteins and T-cell antigen receptor signaling

Progress in Biophysics and Molecular Biology

Volumn 71, Issue 3-4, 1999, Pages 393-403

  Samelson, Lawrence E ^a  

^a Arthr Rheumatism Br Natl I   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN TYROSINE KINASE; T LYMPHOCYTE ANTIGEN;

ANIMAL; ARTICLE; CAENORHABDITIS ELEGANS; CELL COMMUNICATION; DROSOPHILA; HUMAN; IMMUNOLOGY; METABOLISM; NONHUMAN; PHYSIOLOGY; RECEPTOR BINDING; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE;

ANIMALIA; CAENORHABDITIS ELEGANS;

EID: 0032917990     PISSN: 00796107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0079-6107(98)00050-9     Document Type: Review

References (53)

1. Boussiotis V.A., Freeman G.J., Berezovskaya A., Barber D.L., Nadler L.M. Maintenance of human T-cell anergy: blocking of IL-2 gene transcription by activated Rap1. Science. 278:1997;124-128.
2. Buday L., Egan S.E., Rodriguez Viciana P., Cantrell D.A., Downward J. A complex of Grb2 adaptor protein, Sos exchange factor, and a 36-kDa membrane-bound tyrosine phosphoprotein is implicated in ras activation in T-cells. J. Biol. Chem. 269:1994;9019-9023.
3. Cantrell D. T-cell antigen receptor signal transduction pathways. Annu. Rev. Immunol. 14:1996;259-274.
4. Cantrell D. A coordinating role for Vav? Curr. Biol. 8:1998;R535-R538.
5. Chan A.C., Shaw A.S. Regulation of antigen receptor signal transduction by protein tyrosine kinases. Curr. Opin. Immunol. 8:1996;394-401.
6. Clements J.L., Yang B., Ross-Barta S.E., Eliason S.L., Hrstka R.F., Williamson R.A., Koretzky G.A. Requirement for the leukocyte-specific adapter protein SLP-76 for normal T-cell development. Science. 281:1998;416-419.
7. Crespo P., Schuebel K.E., Ostrom A.A., Gutkind J.S., Bustelo X.R. Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product. Nature. 385:1997;169-172.
8. cbl with Grb2 in Jurkat T-cells. J. Biol. Chem. 271:1996;26369-26374.
9. Egan S.E., Giddings B.W., Brooks M.W., Buday L., Sizeland A.M., Weinberg R.A. Association of Sos Ras exchange factor with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature. 363:1993;45-51.
10. Fukazawa T., Reedquist K.A., Trub T., Soltoff S., Panchamoorthy G., Druker B., Cantley L., Shoelson S.E., Band H. The SH3 domain-binding T-cell tyrosyl phosphoprotein p120: demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2 and phosphatidylinositol 3-kinase. J. Biol. Chem. 270:1995;19141-19150.
11. Garboczi D.N., Ghosh P., Utz U., Fan Q.R., Biddison W.E., Wiley D.C. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature. 384:1996;134-141.
12. Garcia K.C., Degano M., Stanfield R.L., Brunmark A., Jackson M.R., Peterson P.A., Teyton L., Wilson I.A. An alpha beta T-cell receptor structure at 2.5 Å and its orientation in the TCR-MHC complex. Science. 274:1996;209-219.
13. Harrison S.C. Peptide-surface association: the case of PDZ and PTB domains. Cell. 86:1996;341-343.
14. Hartley D., Meisner H., Corvera S. Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cbl. J. Biol. Chem. 270:1995;18260-18263.
15. Hutchcroft J.E., Bierer B.E. Signaling through CD28/CTLA-4 family receptors: puzzling participation of phosphatidylinositol-3 kinase. J. Immunol. 156:1996;4071-4074.
16. Jackman J.K., Motto D.G., Sun Q., Tanemoto M., Turck C.W., Peltz G.A., Koretzky G.A., Findell P.R. Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T-cells. J. Biol. Chem. 270:1995;7029-7032.
17. Keane M.M., Rivero-Lezcano O.M., Mitchell J.A., Robbins K.C., Lipkowitz S. Cloning and characterization of cbl-b: a SH3 binding protein with homology to the c-cbl proto-oncogene. Oncogene. 10:1995;2367-2377.
18. Koretzky G.A. The role of Grb2-associated proteins in T-cell activation. Immunol. Today. 18:1997;401-406.
19. Kuriyan J., Cowburn D. Modular peptide recognition domains in eukaryotic signaling. Annu. Rev. Biophys. Biomol. Struct. 26:1997;259-288.
20. Lemmon M.A., Ferguson K.M., Schlessinger J. PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface. Cell. 85:1996;621-624.
21. 2+-stimulated activation of nuclear factor of activated T-cells by a constitutively active Cbl mutant in T-cells. J. Biol. Chem. 272:1997;168-173.
22. Liu Y.C., Liu Y., Elly C., Yoshida H., Lipkowitz S., Altman A. Serine phosphorylation of Cbl induced by phorbol ester enhances its association with 14-3-3 proteins in T-cells via a novel serine-rich 14-3-3-binding motif. J. Biol. Chem. 272:1997;9979-9985.
23. Lowenstein E.J., Daly R.J., Batzer A.G., Li W., Margolis B., Lammers R., Ullrich A., Skolnick D., Bar-Sagi D., Schlessinger J. The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinses to ras signalling. Cell. 70:1992;431-442.
24. Lupher M. Jr., Reedquist K.A., Miyake S., Langdon W.Y., Band H. A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T-cells. J. Biol. Chem. 271:1996;24063-24068.
25. Mayer B.J., Eck M.J. SH3 domains: minding your p's and q's. Curr. Biol. 5:1995;364-367.
26. Meisner H., Conway B.R., Hartley D., Czech M.P. Interactions of Cbl with Grb2 and phosphatidylinositol 3′-kinase in activated Jurkat cells. Mol. Cell. Biol. 15:1995;3571-3578.
27. Motto D.G., Ross S.E., Jackman J.K., Sun Q., Olson A.L., Findell P.R., Koretzky G.A. In vivo association of Grb2 with pp116, a substrate of the T-cell antigen receptor-activated protein tyrosine kinase. J. Biol. Chem. 269:1994;21608-21613.
28. Murphy M.A., Schnall R.G., Venter D.J., Barnett L., Bertoncello I., Thien C.B.F., Langdon W.Y., Bowtell D.D.L. Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice. Mol. Cell. Biol. 18:1998;4872-4882.
29. Musci M.A., Hendricks-Taylor L.R., Motto D.G., Paskind M., Kamens J., Turck C.W., Koretzky G.A. Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T-cell antigen receptor-stimulated protein tyrosine kinases. J. Biol. Chem. 272:1997;11674-11677.
30. Neumeister E.N., Zhu Y., Richard S., Terhorst C., Chan A.C., Shaw A.S. Binding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins. Mol. Cell. Biol. 15:1995;3171-3178.
31. Ota Y., Samelson L.E. The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase. Science. 276:1997;418-420.
32. Pawson T. Protein modules and signalling networks. Nature. 373:1995;573-580.
33. Perlmutter R.M., Levin S.D., Appleby M.W., Anderson S.J., Alberola-Ila J. Regulation of lymphocyte function by protein phosphorylation. Annu. Rev. Immunol. 11:1993;451-499.
34. Peterson E.J., Clements J.L., Fang N., Koretzky G.A. Adaptor proteins in lymphocyte antigen-receptor signaling. Curr. Opin. Immunol. 10:1998;337-344.
35. Pivniouk V., Tsitsikov E., Swinton P., Rathbun G., Alt F.W., Geha R.S. Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76. Cell. 94:1998;229-238.
36. Pleiman C.M., Hertz W.M., Cambier J.C. Activation of phosphatidylinositol-3′ kinase by Src-family kinase SH3 binding to the p85 subunit. Science. 263:1994;1609-1612.
37. Reif K., Buday L., Downward J., Cantrell D.A. SH3 domains of the adapter molecule Grb2 complex with two proteins in T-cells: the guanine nucleotide exchange protein Sos and a 75-kDa protein that is a substrate for T-cell antigen receptor-activated tyrosine kinases. J. Biol. Chem. 269:1994;14081-14087.
38. Scharenberg A.M., Kinet J.P. PtdIns-3,4,5-P3: a regulatory nexus between tyrosine kinases and sustained calcium signals. Cell. 94:1998;5-8.
39. Schuebel K.E., Bustelo X.R., Nielsen D.A., Song B.J.B.M., Goldman D., Lee I.J. Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes. Oncogene. 13:1996;363-371.
40. da Silva A.J., Li Z., de Vera C., Canto E., Findell P., Rudd C.E. Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production. Proc. Natl. Acad. Sci. USA. 94:1997;7493-7498.
41. Tarakhovsky A., Turner M., Schaal S., Mee P.J., Duddy L.P., Rajewsky K., Tybulewicz V.L. Defective antigen receptor-mediated proliferation of B- and T-cells in the absence of Vav. Nature. 374:1995;467-470.
42. Trub T., Frantz J.D., Miyazaki M., Band H., Shoelson S.E. The role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T-cell receptor signaling. J. Biol. Chem. 272:1997;894-902.
43. Tuosto L., Michel F., Acuto O. p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T-cells. J. Exp. Med. 184:1996;1161-1166.
44. Wange R.L., Samelson L.E. Complex complexes: signaling at the TCR. Immunity. 5:1996;197-205.
45. Weiss A., Littman D.R. Signal transduction by lymphocyte antigen receptors. Cell. 76:1994;263-274.
46. Weissman A.M. The T-cell antigen receptor: a multisubunit signaling complex. Chem. Immunol. 59:1994;1-18.
47. Wu J., Motto D.G., Koretzky G.A., Weiss A. Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation. Immunity. 4:1996;593-602.
48. Xavier R., Brennan T., Li Q., McCormack C., Seed B. Membrane compartmentation is required for efficient T-cell activation. Immunity. 8:1998;723-732.
49. Yablonski D., Kuhne M.R., Kadlecek T., Weiss A. Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T-cell. Science. 281:1998;413-416.
50. Zhang R., Alt F.W., Davidson L., Orkin S.H., Swat W. Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene. Nature. 374:1995;470-473.
51. Zhang W., Sloan-Lancaster J., Kitchen J., Trible R.P., Samelson L.E. LAT: the ZAP-70 tyrosine kinase substrate that links T-cell receptor to cellular activation. Cell. 92:1998;83-92.
52. Zhang, W., Trible, R.P., Samelson, L.E., 1998b. LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T-cell activation. Immunity, 9, 239-246.
53. Zhao H., Li Y.Y., Fucini R.V., Ross S.E., Pessin J.E., Koretzky G.A. T-cell receptor-induced phosphorylation of Sos requires activity of CD45, Lck and protein kinase C, but not ERK. J. Biol. Chem. 272:1997;21625-21634.