Epicutaneous and transcutaneous immunization using DNA or proteins

European Journal of Dermatology

Volumn 9, Issue 3, 1999, Pages 169-176

  Kaiserlian, Dominique ^a   Etchart, Nathalie ^a  

^a INSERM   (France)

Author keywords

Dendritic cell; DNA; Gene gun; Langerhans cells; Naked DNA; Skin immunization; Vaccination

Indexed keywords

BETA GALACTOSIDASE; CD4 ANTIGEN; CD8 ANTIGEN; CD86 ANTIGEN; CHOLERA TOXIN; CYTOKINE; DNA VACCINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GREEN FLUORESCENT PROTEIN; IMMUNOGLOBULIN; IMMUNOLOGICAL ADJUVANT; INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PLASMID DNA; RECOMBINANT PROTEIN;

ANTIGEN PRESENTATION; CYTOKINE PRODUCTION; DENDRITIC CELL; DNA SEQUENCE; GENE GUN; GENE TARGETING; HUMAN; IMMUNIZATION; IMMUNOGLOBULIN PRODUCTION; IMMUNOLOGICAL MEMORY; IMMUNOMODULATION; INTERFERON PRODUCTION; INTRADERMAL DRUG ADMINISTRATION; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; KERATINOCYTE; LANGERHANS CELL; NONHUMAN; REVIEW; SUBCUTANEOUS DRUG ADMINISTRATION; TOPICAL DRUG ADMINISTRATION; TRANSDERMAL DRUG ADMINISTRATION; VACCINATION;

ADMINISTRATION, CUTANEOUS; ANIMALS; DENDRITIC CELLS; DNA; HUMANS; IMMUNOLOGIC SURVEILLANCE; PLASMIDS; PROTEINS; SKIN ABSORPTION; SKIN DISEASES; VACCINES, DNA;

EID: 0032907610     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (35)

1. 1. Banchereau J, Steinman RM. 1998. Dendritic cells and the control of immunity. Nature 392: 245-52.
2. 2. Caux C. Pathways of development of human dendritic cells. Eur J Dermatol 1998; 6: 375-84.
3. 3. Brossart P, Bevan MJ. Presentation of exogenous protein antigens on major histocompatibility complex class I molecules by dendritic cells: pathway of presentation and regulation by cytokines. Blood 1997; 90: 1594-9.
4. 4. Donnelly JJ, Ulmer JB, Shiver JW, Liu MA. DNA vaccines. Ann Rev Immunol 1997; 15: 617-48.
5. 5. Fynan EF, Webster RG, Fuller DH, Haynes JR, Santoro JC, Robinson HL. DNA vaccines: protective immunizations by parenteral, mucosal and gene-gun inoculations. Proc Natl Acad Sci 1993; 90: 11478-82.
6. 6. Cardoso A, Sixt N, Vallier A, Fayolle J, Buckland R, Wild F. Measles virus DNA vaccination antibody isotype is determined by the method of immunization and by the nature of both the antigen and the coimmunized antigen. J Virol 1998; 72: 2516-8.
7. 7. Pertner TM, Roberts TR, Haynes JR. Influenza virus nucleoprotein-specific immunoglobulin G subclass and cytokine responses elicited by DNA vaccination are dependent on the route of vector DNA delivery. J Virol 1996; 70: 6119-25.
8. 8. Condon C, Watkins SC, Celluzzi CM, Thompson K, Falo LD. DNA-based immunization by in vivo transfection of dendritic cells. Nature Medicine 1997; 2: 1122.
9. 9. Andree C, Swain WF, Page CP, Macklin MD, Slama J, Hatzis D, Eriksson E. In vivo tansfer and expression of a human epidermal growth factor gene accelerates wound repair. Proc Natl Acad Sci 1994; 91: 12188.
10. 10. Barry MA, Johnston SA. Biological features of genetic immunization. Vaccine 1997; 8: 788.
11. 11. Torres CA, Iwasaki A, Baber AH, Robinson HL. Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations. J Immunol 1997; 158: 4529.
12. 12. Iwasaki A, Torres CAT, Ohashi PS, Robinson HL, Barber BH. The dominant role of bone-marrow-derived cells in CTL induction following plasmid DNA immunization at different sites. J Immunol 1997; 155: 2039.
13. 13. Klinman DM, Secgler JMG, Conover J, Gu M, Rosenberg AS. Contribution of cells at the site of DNA vaccination to the generation of antigen specific immunity and memory. J Immunol 1998; 160: 2388-92.
14. + T cells after gene gun immunzation. J Exp Med 1998; 188: 1075-82.
15. 15. Sato Y, Roman M, Tighe H, Lee D, Corr M, Nguyen MD, Silverman GJ, Lotz M, Carson D, Raz E. Immunostimulatory DNA sequences necessary for effective intradermal gene immunization. Science 1996; 273: 352-4.
16. 16. Roman M, Martin-Orozco H, Goodman JS, Nguyen MD, Sato Y, Ronhaghy A, Kornbluth A, Richman DD, Carson D, Raz E. Immunostimulatory DNA sequences function as T helper-1-promoting adjuvants. Nature Medicine 1997; 3: 849-54.
17. 17. Jacob T, Walker PS, Krieg AM, Udey MC, Vogel JC. Activation of cutaneous dendritic cells by CpG-containing oligonucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA. J Immunol 1998; 161: 3042-9.
18. 18. Krieg AM, Wu T, Weeratna R, Efler SM, Love-Homan L, Yang L, Yi AK, Short D, Davis HL. Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs. Proc Natl Acad Sci 1998; 95: 12631-6.
19. 19. Porgador A, Gilboa E. Bone marrow generated dendritic cell pulsed with a class I-restricted peptides are potent inducers of cytotoxic T lymphocytes. J Exp Med 1995; 182: 255-8.
20. 20. Czemick FI, Brezofsky JA, Carbone DP. Induction of cytotoxic T lymphocytes and anti-tumor immunity with DNA vaccines expressing single T cell epitopes. J Immunol 1996; 156: 2369-75.
21. 21. Thompson SA, Sherritt MA, Medveczky J, Elliott SL, Moss DL, Fernando GJ, Brown LE, Suhrbier AA. Delivery of multiple CD8 cytotoxic T cell epitopes by DNA vaccination. J Immunol 1998; 160: 1717-23.
22. 22. Xiang Z, Ertl HCJ. Manipulation of the immune response to a plasmid-encoded viral antigen by co-inoculation with plasmids expressing cytokines. Immunity 1995; 2: 129-35.
23. 23. Boyle JS, Brady JL, Lew AM. Enhanced responses to a DNA vaccine encoding a fusion antigen that is directed to sites of immune induction. Nature 1998; 392: 408-11.
24. 24. Hedley ML, Curley J, Urban R. Microspheres containing plasmid-encoded antigens elicit cytotoxic T cell responses. Nature Medicine 1998; 4: 365-8.
25. 25. Lu B, Federoff HJ, Wang Y, Goldsmith LA, Scott G. Topical application of viral vectors for epidermal gene transfer. J Invest Dermatol 1997; 108: 803-8.
26. 26. Glenn GM, Matyas GR, Alving CR. Skin immunization made possible by cholera toxin. Nature 1998; 391: 851.
27. 27. Glenn GM, Scharton-Kersten T, Vassell R, Mallett CP, Hale TL, Alving CR. Transcutaneous immunization with cholera toxin protects mice against lethal mucosal toxin challenge. J Immunol 1998; 161: 3211-4.
28. 28. Thestrup-Pedersen K. Which factors are of relevance in the pathogenesis of atopic dermatitis? Eur J Dermatol 1997; 7: 549-53.
29. 29. Castelain M. Atopic dermatitis and delayed hypersensitivity to dust mites. Clin Rev Allergy Immunol 1995; 13: 161-72.
30. 30. Wang LF, Lin JY, Hseih KH, Lin RH. Epicutaneous exposure of protein antigen induces a predominant Th2-like response with high IgE production in mice. J Immunol 1996; 156: 4079-82.
31. 31. Spergel JM, Mizoguchi E, Brewer JP, Martin TR, Bhan AK, Geha RS. Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice. J Clin Invest 1998; 101: 1614-22.
32. 32. Musu T, Gregoire C, David B, Dandeu JP. The relationship between the biochemical properties of allergens and their immunogenicity. Clin Rev Allergy Immunol 1997; 15: 485-98.
33. 33. Hengge UR, Walker PS, Vogel JC. Expression of DNA in human, pig and mouse skin. J Clin Invest 1996; 12: 2911-6.
34. 34. Hengge UR Pfutzner W, Williams M, Goos M, Vogel JC. Efficient expression of naked plasmid DNA in mucosal epithelium: prospective for the treatment of skin lesions. J Invest Dermatol 1997; 111: 605-8.
35. 35. Hengge UR, Chan EF, Foster RA, Walker PS, Vogel JC. Cytokine gene expression in epidermis with biological effects following injection of naked DNA. Nature Genetics 1995; 10: 161-6.