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Volumn 111, Issue 1, 1999, Pages 45-56

In vivo short-term expression of a hypertrophic cardiomyopathy mutation in adult rabbit myocardium: Myofibrillar incorporation without early disarray

Author keywords

Gene transfer; Myofibrils; Recombinant adenovirus; Sarcomere; Troponin T

Indexed keywords

ANIMAL TISSUE; CONFERENCE PAPER; GENE MUTATION; GENE TRANSFER; HEART MUSCLE; HYPERTROPHIC CARDIOMYOPATHY; MALE; NONHUMAN; PATHOGENESIS; RABBIT; SARCOMERE;

EID: 0032906957     PISSN: 1081650X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1525-1381.1999.09416.x     Document Type: Conference Paper
Times cited : (4)

References (42)
  • 1
    • 0029166817 scopus 로고
    • Recent advances in the molecular genetics of hypertrophic cardiomyopathy
    • 1 Marian A.J. & Roberts R. Recent advances in the molecular genetics of hypertrophic cardiomyopathy.   Circulation 92: 1336 1347, 1995.
    • (1995) Circulation , vol.92 , pp. 1336-1347
    • Marian, A.J.1    Roberts, R.2
  • 2
    • 0018378062 scopus 로고
    • Quantitative analysis of cardiac muscle cell disorganization in the ventricular septum of patients with hypertrophic cardiomyopathy
    • 2 Maron B.J. & Roberts W.C. Quantitative analysis of cardiac muscle cell disorganization in the ventricular septum of patients with hypertrophic cardiomyopathy. Circulation. 59: 689 706, 1978.
    • (1978) Circulation. , vol.59 , pp. 689-706
    • Maron, B.J.1    Roberts, W.C.2
  • 3
    • 0028178083 scopus 로고
    • α‐Tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: A disease of the sarcomere
    • 3 Thierfelder L., Watkins H., MacRae C., et al. α‐Tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: A disease of the sarcomere. Cell 77: 701 712, 1994.
    • (1994) Cell , vol.77 , pp. 701-712
    • Thierfelder, L.1    Watkins, H.2    MacRae, C.3
  • 4
    • 0025040392 scopus 로고
    • A molecular basis for familial hypertrophic cardiomyopathy: A β‐cardiac myosin heavy chain gene missense mutation
    • 4 Geisterfer‐Lowrance A.A., Kass S., Tanigawa G., et al. A molecular basis for familial hypertrophic cardiomyopathy: A β‐cardiac myosin heavy chain gene missense mutation. Cell 62: 999 1006, 1990.
    • (1990) Cell , vol.62 , pp. 999-1006
    • Geisterfer‐Lowrance, A.A.1    Kass, S.2    Tanigawa, G.3
  • 5
    • 0028844204 scopus 로고
    • Mutations in the cardiac myosin binding protein‐C gene on chromosome 11 cause familial hypertrophic cardiomyopathy
    • 5 Watkins H., Conner D., Thierfelder L., et al. Mutations in the cardiac myosin binding protein‐C gene on chromosome 11 cause familial hypertrophic cardiomyopathy. Nat. Genet. 11: 434  –437, 1995.
    • (1995) Nat. Genet. , vol.11 , pp. 434-437
    • Watkins, H.1    Conner, D.2    Thierfelder, L.3
  • 6
    • 0028886136 scopus 로고
    • Cardiac myosin binding protein‐C gene splice acceptor site mutation is associated with familial hypertrophic cardiomyopathy
    • 6 Bonne G., Carrier L., Bercovici J., et al. Cardiac myosin binding protein‐C gene splice acceptor site mutation is associated with familial hypertrophic cardiomyopathy. Nat. Genet. 11: 438 440, 1995.
    • (1995) Nat. Genet. , vol.11 , pp. 438-440
    • Bonne, G.1    Carrier, L.2    Bercovici, J.3
  • 7
    • 15844400653 scopus 로고    scopus 로고
    • Mutations in either the essential or regulatory light chains of myosin are associated with a rate myopathy in human heart and skeletal muscle
    • 7 Poetter K., Jiang H., Hassanzadeh S., et al. Mutations in either the essential or regulatory light chains of myosin are associated with a rate myopathy in human heart and skeletal muscle. Nat. Genet. 13: 63 69, 1996.
    • (1996) Nat. Genet. , vol.13 , pp. 63-69
    • Poetter, K.1    Jiang, H.2    Hassanzadeh, S.3
  • 8
    • 0030765610 scopus 로고    scopus 로고
    • Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy
    • 8 Kimura A., Harada H., Park J.‐E., et al. Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy. Nat. Genet. 16: 379 382, 1997.
    • (1997) Nat. Genet. , vol.16 , pp. 379-382
    • Kimura, A.1    Harada, H.2    Park, J.‐E.3
  • 9
    • 0028902929 scopus 로고
    • Mutations in the genes for cardiac troponin T and α‐tropomyosin in hypertrophic cardiomyopathy
    • 9 Watkins H., McKenna W.J., Thierfelder L., et al. Mutations in the genes for cardiac troponin T and α‐tropomyosin in hypertrophic cardiomyopathy. N. Engl. J. Med. 332: 1058 1064, 1995.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1058-1064
    • Watkins, H.1    McKenna, W.J.2    Thierfelder, L.3
  • 10
    • 0029804760 scopus 로고    scopus 로고
    • Expression and functional assessment of a truncated cardiac troponin T that causes hypertrophic cardiomyopathy. Evidence for a dominant negative action
    • 10 Watkins H., Seidman C.E., Seidman J.G., et al. Expression and functional assessment of a truncated cardiac troponin T that causes hypertrophic cardiomyopathy. Evidence for a dominant negative action.   J. Clin. Invest. 98: 2456 2461, 1996.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2456-2461
    • Watkins, H.1    Seidman, C.E.2    Seidman, J.G.3
  • 11
    • 0030611676 scopus 로고    scopus 로고
    • Expression of a mutant (Arg92Gln) human cardiac troponin T, known to cause hypertrophic cardiomyopathy, impairs adult cardiac myocytes contractility
    • 11 Marian A.J., Zhao G., Seta Y., et al. Expression of a mutant (Arg 92 Gln) human cardiac troponin T, known to cause hypertrophic cardiomyopathy, impairs adult cardiac myocytes contractility. Cir. Res. 81: 76 85, 1997.
    • (1997) Cir. Res. , vol.81 , pp. 76-85
    • Marian, A.J.1    Zhao, G.2    Seta, Y.3
  • 12
    • 0029807438 scopus 로고    scopus 로고
    • Mice expressing mutant myosin heavy chains are a model for familial hypertrophic cardiomyopathy
    • 12 Vikstrom K.L., Factor S.M., Leinwand L.A. Mice expressing mutant myosin heavy chains are a model for familial hypertrophic cardiomyopathy. Mol. Med. 2: 556 567, 1996.
    • (1996) Mol. Med. , vol.2 , pp. 556-567
    • Vikstrom, K.L.1    Factor, S.M.2    Leinwand, L.A.3
  • 13
    • 0030067394 scopus 로고    scopus 로고
    • A mouse model for familial hypertrophic cardiomyopathy
    • 13 Geisterfer‐Lowrance A.A.T., Christe M., Conner D.A., et al. A mouse model for familial hypertrophic cardiomyopathy. Science 272: 731 734, 1996.
    • (1996) Science , vol.272 , pp. 731-734
    • Geisterfer‐Lowrance, A.A.T.1    Christe, M.2    Conner, D.A.3
  • 14
    • 0002855734 scopus 로고    scopus 로고
    • Dominant‐negative effect of a mutant cardiac troponin T, known to cause hypertrophic cardiomyopathy in man, on myofibrillar structure in transgenic mice
    • 14 Marian A.J., Oberst L., Nyhm H., et al. Dominant‐negative effect of a mutant cardiac troponin T, known to cause hypertrophic cardiomyopathy in man, on myofibrillar structure in transgenic mice.    J. Invest. Med. 46: 235A, 1998.
    • (1998) J. Invest. Med. , vol.46 , pp. 235A
    • Marian, A.J.1    Oberst, L.2    Nyhm, H.3
  • 15
    • 0024323295 scopus 로고
    • A general method of site‐specific mutagenesis using a modification of the Thermus aquaticus polymerase chain reaction
    • 15 Nelson R.M. & Long G.L. A general method of site‐specific mutagenesis using a modification of the Thermus aquaticus polymerase chain reaction. Anal. Biochem. 180: 147 151, 1989.
    • (1989) Anal. Biochem. , vol.180 , pp. 147-151
    • Nelson, R.M.1    Long, G.L.2
  • 16
    • 0028559768 scopus 로고
    • An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3
    • 16 Bett A.J., Haddara W., Prevec L., Graham F.L. An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3. Proc. Natl. Acad. Sci. U.S.A. 91: 8802 8806, 1994.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 8802-8806
    • Bett, A.J.1    Haddara, W.2    Prevec, L.3    Graham, F.L.4
  • 17
    • 0029029473 scopus 로고
    • Expression of the mutation causing hypertrophic cardiomyopathy disrupts sarcomere assembly in adult feline cardiac myocytes
    • 17 Marian A.J., Yu Q.‐T., Mann D., et al. Expression of the mutation causing hypertrophic cardiomyopathy disrupts sarcomere assembly in adult feline cardiac myocytes. Circ. Res. 77: 98 106, 1995.
    • (1995) Circ. Res. , vol.77 , pp. 98-106
    • Marian, A.J.1    Yu, Q.‐T.2    Mann, D.3
  • 18
    • 85120519352 scopus 로고    scopus 로고
    • 18 Graham F.L. and Prevec L. Manipulation of adenovirus vectors. In: E.J. Murray (ed). Methods in Molecular Biology, vol. 7: Gene Transfer and Expression Protocols. Clifton, NJ: Humana Press, 1991. Pp. 109–127.
  • 19
    • 0023277545 scopus 로고
    • Single‐step method of RNA isolation by acid guanidinium thiocyanate‐phenol‐chloroform extraction
    • 19 Chomczynski P. & Sacchi N. Single‐step method of RNA isolation by acid guanidinium thiocyanate‐phenol‐chloroform extraction. Anal. Biochem. 162: 156 169, 1987.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-169
    • Chomczynski, P.1    Sacchi, N.2
  • 20
    • 0028302366 scopus 로고
    • Human cardiac troponin T. Identification of fetal isoforms and assignment of the TNNT2 locus to chromosome 1q
    • 20 Townsend P.J., Farza H., MacGeon C., et al. Human cardiac troponin T. Identification of fetal isoforms and assignment of the TNNT2 locus to chromosome 1q. Genomics 21: 311 316, 1994.
    • (1994) Genomics , vol.21 , pp. 311-316
    • Townsend, P.J.1    Farza, H.2    MacGeon, C.3
  • 21
    • 0028057433 scopus 로고
    • Molecular basis of cardiac troponin T isoform heterogeneity in rabbit heart
    • 21 Greig A., Hirschberg Y., Anderson P.A., et al. Molecular basis of cardiac troponin T isoform heterogeneity in rabbit heart. Circ. Res. 74: 41 47, 1994.
    • (1994) Circ. Res. , vol.74 , pp. 41-47
    • Greig, A.1    Hirschberg, Y.2    Anderson, P.A.3
  • 22
    • 0020793569 scopus 로고
    • A technique for radiolabelling DNA restriction nuclease fragments to high specific activity
    • 22 Feinberg A.P. & Vogelstein B. A technique for radiolabelling DNA restriction nuclease fragments to high specific activity. Anal. Biochem. 132: 6 13, 1983.
    • (1983) Anal. Biochem. , vol.132 , pp. 6-13
    • Feinberg, A.P.1    Vogelstein, B.2
  • 23
    • 0027496356 scopus 로고
    • Thick filament substructures in Caenorhabditis elegans: Evidence for two population of paramyosin
    • 23 Deitiker P.R. & Epstein H.F. Thick filament substructures in Caenorhabditis elegans: Evidence for two population of paramyosin. J. Cell Biol. 123: 303 311, 1993.
    • (1993) J. Cell Biol. , vol.123 , pp. 303-311
    • Deitiker, P.R.1    Epstein, H.F.2
  • 24
    • 0024296745 scopus 로고
    • Rpaaid purification of mammalian cardiac troponin T and its isoform switching in rat heart during development
    • 24 Jin J.P. & Lin J.J. Rpaaid purification of mammalian cardiac troponin T and its isoform switching in rat heart during development. J. Biol. Chem. 263: 7309 7315, 1988.
    • (1988) J. Biol. Chem. , vol.263 , pp. 7309-7315
    • Jin, J.P.1    Lin, J.J.2
  • 25
    • 0014143313 scopus 로고
    • Procedure for embedding in situ selected cells in vitro
    • 25 Brinkley B.R., Murphy P., Richardson L.C. Procedure for embedding in situ selected cells in vitro.   J. Cell Biol. 35: 279 283, 1967.
    • (1967) J. Cell Biol. , vol.35 , pp. 279-283
    • Brinkley, B.R.1    Murphy, P.2    Richardson, L.C.3
  • 26
    • 9244220682 scopus 로고    scopus 로고
    • Immune response to viral antigens versus transgene product in the elimination of recombinant adenovirus‐infected hepatocytes in vivo
    • 26 Yang Y., Jooss K.U., Su Q., et al. Immune response to viral antigens versus transgene product in the elimination of recombinant adenovirus‐infected hepatocytes in vivo. Gene Ther. 3: 137 144, 1996.
    • (1996) Gene Ther. , vol.3 , pp. 137-144
    • Yang, Y.1    Jooss, K.U.2    Su, Q.3
  • 27
    • 0028832360 scopus 로고
    • Transient expression of genes transferred in vivo into heart using first‐generation adenoviral vectors: Role of the immune response
    • 27 Gilgenkrantz H., Duboc D., Juillard V., et al. Transient expression of genes transferred in vivo into heart using first‐generation adenoviral vectors: Role of the immune response. Hum. Gene Ther. 6: 1265 1274, 1995.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 1265-1274
    • Gilgenkrantz, H.1    Duboc, D.2    Juillard, V.3
  • 28
    • 0029839669 scopus 로고    scopus 로고
    • Avoidance of immune response prolongs expression of genes delivered to the adult rat myocardium by replication‐defective adenovirus
    • 28 Quinones M.J., Leor J., Kloner R.A., et al. Avoidance of immune response prolongs expression of genes delivered to the adult rat myocardium by replication‐defective adenovirus. Circulation 94: 1394  –1401, 1996.
    • (1996) Circulation , vol.94 , pp. 1394-1401
    • Quinones, M.J.1    Leor, J.2    Kloner, R.A.3
  • 29
    • 0027944524 scopus 로고
    • Direct in vivo gene transfer into porcine myocardium using replication‐deficient adenoviral vectors
    • 29 French B.A., Mazur W., Geske R.S., Bolli R. Direct in vivo gene transfer into porcine myocardium using replication‐deficient adenoviral vectors. Circulation 90: 2414  –2424, 1994.
    • (1994) Circulation , vol.90 , pp. 2414-2424
    • French, B.A.1    Mazur, W.2    Geske, R.S.3    Bolli, R.4
  • 30
    • 0019431847 scopus 로고
    • Turnover of cardiac troponin subunits: Kinetic evidence for a precursor pool of troponin‐I
    • 30 Martin A.F. Turnover of cardiac troponin subunits: Kinetic evidence for a precursor pool of troponin‐I. J. Biol. Chem. 256: 964 968, 1981.
    • (1981) J. Biol. Chem. , vol.256 , pp. 964-968
    • Martin, A.F.1
  • 31
    • 0030958086 scopus 로고    scopus 로고
    • Point mutations in human cardiac myosin heavy chain have differential effects on sarcomeric structure and assembly: An ATP binding site change disrupts both thick and thin filaments, whereas hypertrophic cardiomyopathy mutations display normal assembly
    • 31 Becker D.K., Gottshall K.R., Hickey R., et al. Point mutations in human cardiac myosin heavy chain have differential effects on sarcomeric structure and assembly: An ATP binding site change disrupts both thick and thin filaments, whereas hypertrophic cardiomyopathy mutations display normal assembly.   J. Cell Biol. 137: 131 140, 1997.
    • (1997) J. Cell Biol. , vol.137 , pp. 131-140
    • Becker, D.K.1    Gottshall, K.R.2    Hickey, R.3
  • 32
    • 0022498091 scopus 로고
    • Development and progression of left ventricular hypertrophy in children with hypertrophic cardiomyopathy
    • 32 Maron B.J., Spirito P., Wesley Y., Arce J. Development and progression of left ventricular hypertrophy in children with hypertrophic cardiomyopathy.   N. Engl. J. Med. 315: 610 614, 1986.
    • (1986) N. Engl. J. Med. , vol.315 , pp. 610-614
    • Maron, B.J.1    Spirito, P.2    Wesley, Y.3    Arce, J.4
  • 33
    • 0032580520 scopus 로고    scopus 로고
    • Mutations in the gene for cardiac myosin binding protein C and late‐onset familial hypertrophic cardiomyopathy
    • 33 Nimura H., Bachinski L.L., Sangwatanaroj S., et al. Mutations in the gene for cardiac myosin binding protein C and late‐onset familial hypertrophic cardiomyopathy. N. Engl. J. Med. 338: 1248 1257, 1998.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 1248-1257
    • Nimura, H.1    Bachinski, L.L.2    Sangwatanaroj, S.3
  • 34
    • 0026455138 scopus 로고
    • Plasma levels of atrial natriuretic peptide in hypertrophic cardiomyopathy
    • 34 Derchi G., Bellone P., Chiarella F., et al. Plasma levels of atrial natriuretic peptide in hypertrophic cardiomyopathy. Am. J. Cardiol. 70: 1502 1504, 1992.
    • (1992) Am. J. Cardiol. , vol.70 , pp. 1502-1504
    • Derchi, G.1    Bellone, P.2    Chiarella, F.3
  • 35
    • 0027255523 scopus 로고
    • Ventricular expression of brain natriuretic peptide in hypertrophic cardiomyopathy
    • 35 Hasegawa K., Fujiwara H., Doyama K., et al. Ventricular expression of brain natriuretic peptide in hypertrophic cardiomyopathy. Circulation 88: 372 380, 1993.
    • (1993) Circulation , vol.88 , pp. 372-380
    • Hasegawa, K.1    Fujiwara, H.2    Doyama, K.3
  • 36
    • 0030877545 scopus 로고    scopus 로고
    • Overexpression of transforming growth factor‐β1 and insulin‐like growth factor‐1 in patients with idiopathic hypertrophic cardiomyopathy
    • 36 Li R.‐K., Li G., Mickle D.A.G., et al. Overexpression of transforming growth factor‐β1 and insulin‐like growth factor‐1 in patients with idiopathic hypertrophic cardiomyopathy. Circulation 96: 874  –881, 1997.
    • (1997) Circulation , vol.96 , pp. 874-881
    • Li, R.‐K.1    Li, G.2    Mickle, D.A.G.3
  • 37
    • 0030217906 scopus 로고    scopus 로고
    • Direct in vivo gene transfer to canine myocardium using a replication‐deficient adenovirus vector
    • 37 Magovern C.J., Mack C.A., Zhang J., et al. Direct in vivo gene transfer to canine myocardium using a replication‐deficient adenovirus vector. Ann. Thorac. Surg. 62: 425 433, 1996.
    • (1996) Ann. Thorac. Surg. , vol.62 , pp. 425-433
    • Magovern, C.J.1    Mack, C.A.2    Zhang, J.3
  • 38
    • 0029111553 scopus 로고
    • Percutaneous transluminal gene transfer into canine myocardium in vivo by replication‐defective adenovirus
    • 38 Li J.J., Ueno H., Pan Y., et al. Percutaneous transluminal gene transfer into canine myocardium in vivo by replication‐defective adenovirus. Cardiovasc. Res. 30: 97 105, 1995.
    • (1995) Cardiovasc. Res. , vol.30 , pp. 97-105
    • Li, J.J.1    Ueno, H.2    Pan, Y.3
  • 39
    • 0027527177 scopus 로고
    • Efficient gene transfer into myocardium by direct injection of adenovirus vectors
    • 39 Guzman R.J., Lembatchard P., Crystal R.G., et al. Efficient gene transfer into myocardium by direct injection of adenovirus vectors. Circ. Res. 73: 1202 1207, 1993.
    • (1993) Circ. Res. , vol.73 , pp. 1202-1207
    • Guzman, R.J.1    Lembatchard, P.2    Crystal, R.G.3
  • 40
    • 0030878260 scopus 로고    scopus 로고
    • Gene recombination in postmitotic cells: Targeted expression of Cre Recombinase provokes cardiac‐restricted, site specific rearrangement in adult ventricular muscle in vivo
    • 40 Agah R., Frenkel P.A., French B.A., et al. Gene recombination in postmitotic cells: Targeted expression of Cre Recombinase provokes cardiac‐restricted, site specific rearrangement in adult ventricular muscle in vivo. J. Clin. Invest. 100: 169 179, 1997.
    • (1997) J. Clin. Invest. , vol.100 , pp. 169-179
    • Agah, R.1    Frenkel, P.A.2    French, B.A.3
  • 41
    • 0030271599 scopus 로고    scopus 로고
    • Adenovirus‐mediated gene transfer into infarcted myocardium: Feasibility, timing, and location of expression
    • 41 Leor J., Quinones M.J., Patterson M., et al. Adenovirus‐mediated gene transfer into infarcted myocardium: Feasibility, timing, and location of expression.   J. Mol. Cell Cardiol. 28: 2057 2067, 1996.
    • (1996) J. Mol. Cell Cardiol. , vol.28 , pp. 2057-2067
    • Leor, J.1    Quinones, M.J.2    Patterson, M.3
  • 42
    • 0029834848 scopus 로고    scopus 로고
    • Muscle differentiation during repair of myocardial necrosis in rats via gene transfer with MyoD
    • 42 Murray C.E., Kay M.A., Bartosek T., et al. Muscle differentiation during repair of myocardial necrosis in rats via gene transfer with MyoD.    J. Clin. Invest. 98: 2209 2217, 1996.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2209-2217
    • Murray, C.E.1    Kay, M.A.2    Bartosek, T.3


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