Expression and functional assessment of a truncated cardiac troponin T that causes hypertrophic cardiomyopathy: Evidence for a dominant negative action

Journal of Clinical Investigation

Volumn 98, Issue 11, 1996, Pages 2456-2461

  Watkins, Hugh ^a   Seidman, Christine E ^b   Seidman, J G ^c   Feng, H S ^d   Sweeney, H Lee ^d,e  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

cardiac mechanics; cardiac muscle; contractility; hypertrophic cardiomyopathy; troponin T

Indexed keywords

TROPONIN T;

ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CARBOXY TERMINAL SEQUENCE; FUNCTIONAL ASSESSMENT; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; HYPERTROPHIC CARDIOMYOPATHY; MISSENSE MUTATION; MUSCLE FIBER MEMBRANE CONDUCTANCE; MYOTUBE; PRIORITY JOURNAL; PROTEIN STABILITY; SARCOMERE;

EID: 0029804760     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119063     Document Type: Article

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